• Title/Summary/Keyword: Particle Transition

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Enhancement of Dissolution Properties of Poorly Soluble Drugs(IV) -Micronization of Furosemide by Recrystallization Method- (난용성 약물의 용출 증가(제4보) -재결정법에 의한 푸로세미드의 미세화-)

  • Koh, Ik-Bae;Shin, Sang-Chul;Oh, In-Joon
    • Journal of Pharmaceutical Investigation
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    • v.18 no.2
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    • pp.55-59
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    • 1988
  • The size of furosemide was reduced by the recrystallization method in order to increase the dissolution rate of the drug. Surfactants or hydrophilic polymers were used to suppress the aggregation in the crystal formation-growth process of microparticles by dispersing action. Dissolution rate of microparticles increased remarkably due to the size reduction of microparticle. The particle size decreased with increasing the concentration of the drug and the dispersing agents, i.e., surfactants or hydrophilic polymers. No polymorphic transition occurred during the microcrystallization process, but the habit of crystal formation was altered in the case of anionic surfactant.

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Flow Visualization of Turbulent Flow around a Sphere (구(球) 주위 난류유동의 정량적 가시화)

  • Jang, Young-Il;Lee, Sang-Joon
    • 한국가시화정보학회:학술대회논문집
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    • 2005.12a
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    • pp.50-53
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    • 2005
  • The turbulent flow around a sphere was investigated in a streamwise meridian plane using two experimental techniques: smoke-wire flow visualization in wind tunnel at Re=5,300 and PIV measurements in a circulating water channel at Re=7,400. The smoke-wire visualization shows flow separation points near an azimuthal angle of $90^{\circ}$, recirculating flow, transition from laminar to turbulent shear layer, evolving vortex roll-up and fully turbulent eddies in the sphere wake. In addition, the mean flow pattern extracted by particle tracing method in water tunnel at Re= 14,500 reveals two distinct comparable toroidal(not closed) vortices in the recirculation region. The mean velocity field measured using a PIV technique demonstrates the detailed wake configuration of close symmetric recirculation and near-wake configuration with two toroidal vortices, reversed velocity zone and vorticity contours.

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Numerical Analysis on Flow Field Around a Bluff Body by LES(I) (LES에 의한 사각형 Bluff Body 주위 유동장 수치해석(I))

  • Jang, D.S.;Lee, Y.W.;Doh, D.H.;Bae, D.S.;Kim, N.S.
    • Journal of Power System Engineering
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    • v.4 no.3
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    • pp.40-47
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    • 2000
  • The turbulent flow with wake, reattachment and recirculation flow is very important from the viewpoint of engineering. But that is still difficult because of especially the unsteady problems which are related with the vehicle dynamics and the aerodynamics noise. This paper evaluate LES that can analyze about all fluid flow region including the laminar, transition and turbulent. So we compare the results of LES with those of PIV measurement and Reynolds averaging models. In conclusion, LES predicts flow behavior better than Reynolds averaging models.

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Synthesis of MnFeP1-xAsx Nanocrystalline Powders by High-Energy Ball Milling (고에너지볼밀링을 이용한 MnFeP1-xAsx 나노분말의 합성)

  • 조영환
    • Journal of Powder Materials
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    • v.10 no.2
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    • pp.129-135
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    • 2003
  • Nanocrystalline powders of $MnFeP_{1-x}As_x$(x=0.45-0.6) have been synthesized by mechanochemical reaction at room temperature using high-energy ball milling from mixtures of Mn, Fe, P, and As Powders. It has been found that a mechanically induced self-propagating reaction (MSR) occurs within 2 hours of milling and it produces very fine polycrystalline powder having a hexagonal $Fe_2P$ structure. Further milling up to 24 hours did not change the crystalline and average particle sizes or the phase composition of the milling product. When x is 0.65, no reaction among the reactants has been observed even after 24 hours of milling. As the P content decreases in $MnFeP_{1-x}As_x$, the incubation time for the MSR has increased and the lattice constants in both a and c axes have changed.

Spider Invasion Across the Galaxy

  • Hui, Chung-Yue
    • Journal of Astronomy and Space Sciences
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    • v.31 no.2
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    • pp.101-120
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    • 2014
  • The nature of the exotic stellar corpses which reincarnate by consuming their companion is reviewed. Apart from sucking life from their partners, they are actually eating the doomed companions away by their deadly and powerful particle/radiation beams. Such situation resembles that a female "black widow" spider that eats its mate after mating. These celestial zombies are called - Millisecond pulsars (MSPs). In this review article, I will focus on the effort of Fermi Asian Network (FAN) in exploring these intricating objects over the last five years. Two special classes of MSPs are particularly striking. Since Fermi Gamma-ray Space Telescope has started surveying the gamma-ray sky, the population of "black widows" has been boosted. Another dramatic class is so-called "redbacks" (Australian cousin of "black widows") which has just emerged in the last few years. These MSPs provide us with a long-sought missing link in understanding the transition between accretion-powered and rotation-powered systems. The strategy of hunting MSPs through mulitwavelength observations of the unidentified Fermi objects is also reviewed.

Effect of pH on the Luminescence of $(Y,Gd)BO_3:Eu^{3+}$ Phosphor Prepared by the Coprecipitation Method

  • Lee, Gwan-Hyoung;Kang, Shin-Hoo
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1514-1517
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    • 2005
  • The $(Y,Gd)BO_3:Eu^{3+}$ phosphor was made by coprecipitation method. The precipitated powders were amorphous. The value of pH in the process of coprecipitation was critical for the luminescence of phosphors. The particle size and morphology were influenced by pH value. The lower calcination temperature and hydrothermal synthesis leads to the distortion of lattices. The distorted lattices changed the symmetry of $Eu^{3+}$ site. The broken inversion symmetry in the distorted lattice caused the increased emission of $^5D_0{\rightarrow}^7D_2$ transition.

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Fine YBaCuO Powder Prepared by Sol-gel Method

  • Soh, Deawha;Li, Fenghua;Wang, Jue;Fan, Zhanguo
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07a
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    • pp.470-473
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    • 2002
  • In order to get proper original suspension for the electrophoresis process of making YBaCuO films, YBaCuO superconductor powder was prepared with the Sol-gel method. The composition of the powder was analyzed by X-ray diffraction, which was identified as YBa$_2$Cu$_3$O$\sub$7-x/(Yl23) phase. The form of YBaCuO single particle was showed to be spherical by scanning electronic microscope and its size was among 0.2-1 $\mu\textrm{m}$. The critical transition temperature (T$\sub$c/) and the critical current density (J$\sub$c/) were measured with the four-probe, method. The T$\sub$c/ was about 91 K, and the J$\sub$c/ was 5-30 A/$\textrm{cm}^2$.

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Effect of Silica Addition on Phase Transformation Characteristics of Heat-Treated Combustion-Synthesized TiO2 Nanoparticles (실리카가 첨가된 연소합성 TiO2 나노입자의 열처리에 따른 상변환 특성)

  • Kim, Min-Su;Lee, Gyo-Woo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.33 no.3
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    • pp.186-193
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    • 2009
  • In this article, the effect of silica addition on the phase transformation characteristics of $TiO_2$ nanoparticles synthesized by using an $O_2$-enriched coflow, hydrogen, diffusion flame was investigated. TTIP(titanium tetra-isopropoxide) and TEOS(tetraethyl-orthosilicate) were used as precursors for $TiO_2$ and $SiO_2$ nanoparticles, respectively. Based on the results from TEM and XRD analysis, it is believed that the silica addition on the flame synthesis of $TiO_2$ nanoparticles reduces the particle size distribution and raises the temperature of the phase transition from anatase to rutile. But the reduced sizes of the synthesized particles due to the silica addition made the sintering and phase transformation of particles more easily.

A Fundamental Study on the Workability of High Strength Concrete according to Kinds of Aggregate (골재의 종류에 따른 고강도 콘크리트의 시공 특성에 관한 기초적 연구)

  • 최희용;김규용;최민수;김진만;심옥진;김무한
    • Proceedings of the Korea Concrete Institute Conference
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    • 1996.04a
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    • pp.12-17
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    • 1996
  • It is true that aggregate strength is usually not a factor in normal concrete strength because, the aggregate particle is several times stronger than the matrix and the transition zone in concrete. In other words, with most natural aggregates the strength of the aggregate is hardly utilized because the failure is determined by the other two phases. But aggregate characteristics that are significant to concrete technology include porosity, grading or size distribution, moisture absorption, shape and surface texture, crushing strength, elastic modulus, and the type of deleterious substances present. Therefore, in the area of high strength concrete, concrete is much more influenced by properties of aggregate. This experiment is performed to investigate how kinds of aggregare influence on the workability of high strength concrete. In this experiment, four types of aggregate is used, that is crushed river aggregate, crushed stone, recycled aggregate of low strength and recycled aggregate of high strength. In this study, we scrutinize a fundmental study on the workability of high strength concrete according to kinds of aggregate.

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A Fundamental Study on the Engineering Properties of High Strength Concrete addording to Kinds of Aggregate (골재의 종류에 따른 고강도 콘크리트의 공학적 특성에 관한 기초적 연구)

  • 김규용;최희용;김진만;남상일;심옥진;김무한
    • Proceedings of the Korea Concrete Institute Conference
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    • 1996.04a
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    • pp.18-23
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    • 1996
  • Since at least three-quarters of the volume of concrete is occupied by aggregate, it is not surprising that its quality is considerable importance. Not only may the aggregate limit the strength of concrete, as weak aggregate cannot porduce strong concrete, but the properties of aggregate greatly affect the durability and sructural performance of concrete. But, it is ture that aggregate strength is usually not a factor in normal concrete strength because the aggregate particle is several times stronger than the matrix and the transition zone in concrete. This study is to consider the influence the strength of concrete according to the kinds of aggregate, such as crushed river rocks, curshed rocks, high strength recycled aggregate, low strength recycled aggregate at water cement ratio 0.25. It is possible to concern the important of the mechanical role of aggegate for the high strength concrete.

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