• 제목/요약/키워드: Partial response

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A Case of Pulmonary Tuberculosis with Delayed Diagnosis Due to the Temporary Clinical Improvement After Use of Levofloxacin and Amikacin Under the Impression of Community Acquired Pneumonia (폐렴을 의심하여 Levofloxacin과 Amikacin을 사용 후 일시적 호전을 보여 진단이 늦어진 폐결핵 1예)

  • Lee, Hee Seok;Kang, Young Ae;Oh, Jin Young;Lee, Jae Ho;Yoo, Chul Gyu;Lee, Choon-Taek;Kim, Young Whan;Han, Sung Koo;Shim, Young-Soo;Yim, Jae-Joon
    • Tuberculosis and Respiratory Diseases
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    • v.55 no.4
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    • pp.395-401
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    • 2003
  • Fluoroquinolone is one of the first-line antibiotics recommended for treating community-acquired pneumonia. However, using fluroquinolones for presumptive community-acquired pneumonia can delay the diagnosis and the treatment of pulmonary tuberculosis because of its strong activity against mycobacteria. Here, we report a case of a 54-year-old female taking immunosuppressants after a renal transplant whose diagnosis of pulmonary tuberculosis was delayed as a result of the use of levofloxacin and amikacin under the original impression of community-acquired pneumonia. This case suggests that clinicians should consider the possibility of pulmonary tuberculosis in the case of a partial response of the pneumonia to flouroquinolones and/or aminoglycosides.

Analysis of the Korean Real Estate Market and Boosting Policies Focusing on Mortgage Loans: Using System Dynamics (주택담보대출 규제 완화에 따른 부동산시장 영향 분석: 시스템다이내믹스 모형 개발)

  • Hwang, Sung-Joo;Park, Moon-Seo;Lee, Hyun-Soo;Yoon, You-Sang
    • Korean Journal of Construction Engineering and Management
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    • v.11 no.1
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    • pp.101-112
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    • 2010
  • The Korean real estate market currently is experiencing a slowdown due to the global economic crisis which has resulted from subprime mortgage lending practices. In response, the Korean government has enforced various policies, based on intend to deregulate real estate speculation, such as increasing the Loan to value ratio (LTV) in order to stimulate housing supply, demand and accompanying housing transactions. However, these policies have appeared to result in deep confusion in the Korean housing market. Furthermore, analyses for housing market forecasting particularly those which examine the impact of the international financial crisis on the Korean real estate market have been partial and fragmentary. Therefore, a comprehensive and systematical approach is required to analyze the real estate financial market and the causal nexus between market determining factors. Thus, with an integrated perspective and applying a system dynamics methodology, this paper proposes Korean Real Estate and Mortgage Market dynamics models based on the fundamental principles of housing markets, which are determined by supply and demand. As well, the potential effects of the Korean government's deregulation policies are considered by focusing on the main factor of these policies: the mortgage loan.

Evaluation of Seismic Behavior for RC Moment Resisting Frame with Masonry Infill Walls (비내력벽을 가진 RC모멘트저항골조의 지진거동 평가)

  • Ko, Hyun;Kim, Hyun-Su;Park, Yong-Koo;Lee, Dong-Guen
    • Journal of the Earthquake Engineering Society of Korea
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    • v.14 no.5
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    • pp.13-22
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    • 2010
  • Masonry infill walls are frequently used as interior partitions and exterior walls in low- or middle- rise RC buildings. In the design and assessment of buildings, the infill walls are usually treated as non-structural elements and they are ignored in analytical models because they are assumed to be beneficial to the structural responses. Therefore, their influences on the structural response are ignored. In the case of buildings constructed in the USA in highly seismic regions, infill walls have a lower strength and stiffness than the boundary frames or they are separated from the boundary frames. Thus, the previously mentioned assumptions may be reasonable. However, these systems are not usually employed in most other countries. Therefore, the differences in the seismic behaviors of RC buildings with/without masonry infill walls, which are ignored in structural design, need to be investigated. In this study, structural analyses were performed for a masonry infilled low-rise RC moment-resisting frame. The infill walls were modeled as equivalent diagonal struts. The seismic behaviors of the RC moment-resisting frame with/without masonry infill walls were evaluated. From the analytical results, masonry infill walls can increase the global strength and stiffness of a structure. Consequently, the interstory drift ratio will decrease but seismic forces applied to the structure will increase more than the design seismic load because the natural period of the structure decreases. Partial damage of the infill walls by the floor causes vertical irregularity of the strength and stiffness.

Changes in Growth and Yield of Strawberry (cv. Maehyang and Seolhyang) in Response to Defoliation during Nursery Period (딸기 '매향'과 '설향'의 육묘기 자묘 적엽이 생육 및 수량에 미치는 영향)

  • Kim, Dae-Young;Kim, Tae-Il;Kim, Woon-Seop;Kang, Yun-Im;Yun, Hyung-Kweon;Choi, Jong-Myung;Yoon, Moo-Kyung
    • Journal of Bio-Environment Control
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    • v.20 no.4
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    • pp.283-289
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    • 2011
  • This study was conducted to examine the effects of defoliation treatment on the growth and yield of strawberry ($Fragaria{\times}ananassa$ cv. Maehyang and Seolhyang) during nursery period. Leaves of strawberry plantlet had been removed except two, three and four fully expanded leaves until planting date. As the intensity of defoliation was strong, the petiole length was reduced and overgrowth of strawberry plantlet was suppressed. Outer diameter of crown in defoliation treatments significantly decreased but inner diameter of crown was not significant. Number of primary roots of the 3 leaves or 4 leaves defoliation treatment generally tended to increase, but there was not significantly different among treatments. Fresh weight and leaf area in the defoliation treatments significantly decreased and the root weight were higher in partial 3 leaves or 4 leaves defoliation treatment but was not significantly different among treatments. Because T/R ratio decreased significantly as growth inhibition of above-ground part compared to underground part, it is considered easy to take rooting after plantlet plating. As the intensity of defoliation was strong, chlorophyll contents tended to decrease significantly. Reduction of the endogenous nitrogen by defoliation effectively led to promote floral differentiation at low temperature and short day condition. This promoted timing of budding and flowering and also induced uniform flowering after plantlet planting. Marketable fruit yield of 3 leaves defoliation treatment tended to be higher than the control.

Development and Performance Evaluation of Anti-cavitation Paint with a Lamella Glass-flake (판상형 Glass-flake를 이용한 내캐비테이션 도료 개발 및 성능평가)

  • Park, Hyeyoung;Kim, Sung-gil;Kim, Sang-suk;Choi, I-chan;Kim, Byungwoo;Kim, Seung-jin
    • Korean Chemical Engineering Research
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    • v.54 no.2
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    • pp.145-151
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    • 2016
  • In response to the cavitation caused by the partial vacuum caused by the fluid flow, a paint was developed by dispersing the lamella-shaped glass-flake in resin for anti-cavitation. This composite paint was developed by using the inorganic filler (lamella shaped glass-flake) and the NBR (Acrylonitrile-butadiene rubber) which was modified epoxy resin. Especially, the glass-flake was a thin film with a thickness of about 100~200 nm and length of about $20{\sim}30{\mu}m$, the aspect ratio was about 200 to 300 times that of the plate-shaped. So the paint for anti-cavitation have shown excellent performance in corrosion resistance. The results of evaluating anti-cavitation performance was below, tensile strength $4.8{\sim}6N/mm^2$ or more, rupture elongation 30% or higher, abrasive speed $10mm^2/h$ or less. In particular, it showed more than twice the superior performance compared to existing advanced foreign products in anti-cavitation performance evaluation.

A Study on the Safety Distance of Benzene and Acrylonitrile Releases in Sccordance with Dike and Hole Size (벤젠 및 아크릴로나이트릴 누출시 방류벽 유무 및 누출공에 따른 피해 영향범위 산정에 관한 연구)

  • Kawg, Youngmin;Oak, Jaemin;Yoon, Sukyoung;Jung, Seungho
    • Journal of the Korean Institute of Gas
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    • v.22 no.1
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    • pp.18-25
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    • 2018
  • As the industries become more developed, the amounts of hazardous materials have been increased. Because of that, the possibility of accidents in plants is expected to increase. Especially, the dispersions of toxic materials cause serious effect to human life and environment, So it is very important to confirm safety distance of discharge accident. For this paper, we proposed new algorithms for toxic liquid, such as benzene and acrylonitrile. and using this argorithm, we are going to predict safety distance. The scenario of accidental release was assumed to be the release of entire quantity in 10 minutes is defined as worst-case scenario and Instantaneous release. Also the release from a partial rupture of line is used as an alternative case scenarios as NICS(National Institute of Chemical Safety) guidelines. Using ALOHA program and the algorithm for liquid toxic materials and suggested the graph, as well as correlated equations which can utilize emergency responders.

Application of Modified Mupit for the Recurrent Vulva Cancer in Brachytherapy

  • Kim, Jong-Sik;Jung, Chun-Young;Oh, Dong-Gyoon;Song, Ki-Won;Park, Young-Hwan
    • 대한방사선치료학회:학술대회논문집
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    • 2005.06a
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    • pp.23-26
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    • 2005
  • Introduction: To evaluate whether modified MUPIT applicator can effectively eradicate recurrent tumor in uterine cervix cancer and reduce rectal complication after complete radiation treatment. Methods and Materials: Modified MUPIT applicator basically consists of an acrylic cylinder with flexible brain applicator , an acrylic template with a predrilled array of holes that serve as guides for interstitial needles and interstitial needles. CT scan was performed to determine tumor volume and the position of interstitial needles. Modified MUPIT applicator was applied to patient in operation room and the accuracy for position of interstitial needles in tumor volume was confirmed by CTscan. Brachytherapy was delivered using modified MUPIT applicator and RALS (192-Ir HDR) after calculated computer planning by orthogonal film. The daily dose was 600cGy and the total dose was delivered 3000cGy in tumor volume by BID. Rectal dose was measured by TLD at 5 points so that evaluated the risk of rectal complication. Result: The application of modified MUPIT applicator improved dramatically dose distributions in tumor volume and follow-up of 3 month for this patient was clinically partial response without normal tissue complication, Rectal dose was measured 34.1cGy, 57.1cGy, 103.8cGy, 162.7cGy, 165.7cGy at each points, especially the rectal dose including previous EBRT and ICR was 34.1cGy, 57.1cGy Conclusion: Patients with locally recurrent tumor in uterine cervix cancer treated with modified MIUPIT applicator can expect reasonable rates of local control. The advantages of the system are the fixed geometry Provided by the template and cylinders, and improved dose distributions in irregular tumor volume without rectal complication

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Tides and Currents of Kamag Bay in July-August 1994 (1994년 7-8월 가막만의 조석 및 해류)

  • LEE Jae Chul;CHOO Hyo Sang;LEE Kyu Hyong;CHO Kyu Dae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.5
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    • pp.624-634
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    • 1995
  • Tides at both of northern and southern entrances of Kamag Bay were compared by deploying tide gauges for 18 days during July-August 1994. To examine the response of the inner bay to the tidal waves through both entrances, a current meter was moored at the eastern pan of the inner bay. Current meter mooring failed at the northern entrance (Yosu) while the current data was collected for only 5 days at the southern site (Songdo). Maximum range was 357 and 352 cm at Yosu and Songdo, respectively. Respective amplitudes for M2, S2 Kl O1 tides of 95.5, 48.8, 20.5, 14.0cm at Yosu and 93.6, 47.2, 21.3, 13.1cm at Songdo yielded the form numbers of 0.23 and 0.24, respectively, both of which belong to the predominantly semidiurnal tide, Contributions from the overtides and compound tides were less than $4\%^ at both sites. Differences in Greenwich phase of major partial tides between two sites were negligible. Maximum speed of tidal current was about 100cm/sec at the southern entrance and about 40cm/sec at the inner bay. Residual current speed was 17cm/sec southwestward at the southern entrance and 0.9cm/sec southeastward at the inner bay. Temporal change in current at the inner bay showed that the wind had a significant influence upon the circulation in Kamag Bay.

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Efficacy of Nab-Paclitaxel Plus Gemcitabine and Prognostic Value of Peripheral Neuropathy in Patients with Metastatic Pancreatic Cancer

  • You, Min Su;Ryu, Ji Kon;Choi, Young Hoon;Choi, Jin Ho;Huh, Gunn;Paik, Woo Hyun;Lee, Sang Hyub;Kim, Yong-Tae
    • Gut and Liver
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    • v.12 no.6
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    • pp.728-735
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    • 2018
  • Background/Aims: The combination of nab-paclitaxel and gemcitabine (nab-P/Gem) is widely used for treating metastatic pancreatic cancer (MPC). We aimed to evaluate the therapeutic outcomes and prognostic role of treatment-related peripheral neuropathy in patients with MPC treated with nab-P/Gem in clinical practice. Methods: MPC patients treated with nab-P/Gem as the first-line chemotherapy were included. All 88 Korean patients underwent at least two cycles of nab-P/Gem combination chemotherapy (125 and $1,000mg/m^2$, respectively). Treatment-related adverse events were monitored through periodic follow-ups. Overall survival and progression-free survival were estimated by the Kaplan-Meier method, and the Cox proportional hazards regression linear model was applied to assess prognostic factors. To evaluate the prognostic value of treatment-related peripheral neuropathy, the landmark point analysis was used. Results: Patients underwent a mean of $6.7{\pm}4.2$ cycles during $6.3{\pm}4.4$ months. The median overall survival and progression-free survival rates were 14.2 months (95% confidence interval [CI], 11.8 to 20.3 months) and 8.4 months (95% CI, 7.1 to 13.2 months), respectively. The disease control rate was 84.1%; a partial response and stable disease were achieved in 30 (34.1%) and 44 (50.0%) patients, respectively. Treatment-related peripheral neuropathy developed in 52 patients (59.1%), and 13 (14.8%) and 16 (18.2%) patients experienced grades 2 and 3 neuropathy, respectively. In the landmark model, at 6 months, treatment-related peripheral neuropathy did not have a significant correlation with survival (p=0.089). Conclusions: Nab-P/Gem is a reasonable choice for treating MPC, as it shows a considerable disease control rate while the treatment-related peripheral neuropathy was tolerable. The prognostic role of treatment-related neuropathy was limited.

Sudden Deafness (돌발적난청)

  • 조중환;류태현
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1976.06a
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    • pp.85.3-86
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    • 1976
  • Sudden deafness requires immediate investigation and treat if there is to be any prospect of salvaging the hearing. It present an otological emergency and a diagnostic challenge. Sn Sudden sensorineural deafness can be caused by a wide variety of pathologies. A battery of tests and investigations must be performed forthwith if treatment is to be started without further delay. The concept that nothing can be done for the patient with sensori-neural deafness must be abandoned. Some pathologies causing sudden deafness are not amenable to therapy or can show only partial reversibility. But there are several causes, showing little or no spontaneous recovery, which do responed to appropriate treatment. It is important to identify them and concentrate on their management. The age and sex ratios and the unilaterral or bilateral nature of the lesion are related to the etiology and depend upon which type of case is included in the series. Though individually rare, collecting for about 2.5 per cent of new otoloical patients. Some 70 per cent of cases are unilateral. Viral, bacterial and treponemal infections accounted for about 30 per cent of the cases. Some 16 per cent were due to vascular lesions of the cochlea. In almost 22 per cent there was no obvious cause (idiopathic), they occurred in young adult and were either sensory or neural. About 12 per cent were traumatic and 9 per cent were ototoxic in origin. The remaining 11 per cent were due to a group of rarities. The two vital factors are the site of the lesion and the duration of the hearing loss. The earlier these are diagnosed and treated the better the response. The etiology, pathology and treatment are reviewed.

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