• Journal of the Korean Data and Information Science Society
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• 제14권3호
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• pp.707-714
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• 2003

Because of complex aliasing, nonregular designs have traditionally been used for screening only main effects. However, complex aliasing actually may allow some interactions entertained and estimated without making additional runs. According to hierarchical principle, the minimum aberration has been used as an important criterion for selecting regular fractional factorial designs. The criterion is not applicable to nonregular designs. In this paper, we give a criterion for choosing fractional factorial designs based on the fan theory. The criterion is focused on the partial ordering given by set inclusion on estimable sets which is called leaves.

• 약학회지
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• 제42권6호
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• pp.545-551
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• 1998

Near Infrared transmittance Spectroscopy (NIRS) was used to evaluate and quantify the pharmaceutical active compounds. In the paper, taurine (2-Aminoethanesulfonic acid) was quantitatively analyzed in commercial pharmaceutical preparations. For calibration a central composite factorial design was used to determine concentrations of ingredients in reference samples. For the quantitative analysis of taurine, the most suitable data analysis method includes the calculation of second derivatives and a partial least squares regression (PLSR) model. By NIR spectrometry, combined with PLSR, the taurine concentration was successfully predicted with a relative standard error of prediction (SEP) lower than 1.04%.

• Journal of Advanced Marine Engineering and Technology
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• 제39권1호
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• pp.8-12
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• 2015

비에스테르화 바이오 디젤유는 에스테르화 공정을 거치지 않기 때문에 공정에 드는 비용이 절감되며 경유에 5%로 혼합하여 전자제어 분사식 디젤엔진에 사용할 경우 에스테르화 바이오 디젤유보다 경유에 더 유사한 성능을 나타내었다. 이러한 연구를 바탕으로 경유에 5% 혼합된 비에스테르화 바이오 디젤유를 전자제어 분사식 디젤엔진에 적용하기 위해서는 성능 최적화가 필요하다. 본 연구에서는 비에스테르화 바이오 디젤유의 성능 최적화를 위한 기초 실험으로 연료소비율, 질소산화물 및 도시평균유효압력을 반응치로 정하고 제어 가능한 6가지 인자에 대해서 그 영향력을 평가하고자 부분요인배치법을 이용하여 25%와 50%의 부분 부하에서 실험을 수행하였다. 그 결과 6가지 인자 중 분사시기 및 커먼레일압력이 가장 큰 영향을 미쳤고 각 부하에서 영향의 크기는 다르게 나타났다.

• 전기학회논문지
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• 제59권1호
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• pp.108-112
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• 2010

Design of experiment (DOE) method is employed for a systematic and highly efficient optimization of Ga-doped ZnO thin films synthesized by pulsed laser deposition (PLD) process. We sequentially adopted fractional-factorial design (FD) and central composite design (CCD) of the DOE methods. In fractional-FD stage, significant factors to make conductive electrode are found to target-substrate (T-S) distance and oxygen partial pressure. Moreover, correlation among the process factors is elucidated using surface profile modeling. Electrical properties of the GZO films grown on a glass substrate had been optimized to find that the lowest electrical resistivity of about $1.8'10^{-4}Wcm$ which was acquired with the T-S distance and the oxygen pressure of 4 cm and 7 mTorr, respectively. During the DOE-fueled optimization process, the transparency of the GZO films is ensured higher than 85 %.

• 한국의류학회지
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• 제43권4호
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• pp.506-520
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• 2019

This study first investigates relationships among fashion consumer's positive emotion toward social value seeking activities (SVSA), enterprise image (EI), enterprise-perceived quality (EPQ), and purchase intention. Additionally, it demonstrates if the confirmed relationships are different in similar SVSA between social enterprise and cause-related marketing (CRM). An online experiment using a 2 (the implementation organization of social values: social enterprise vs CRM) ${\times}2$ (SVSA: support of vulnerable group vs environmental protection) factorial design was conducted to test the established hypotheses. Participants were randomly assigned to one of four conditions, and the collected data were analyzed using a partial least squares structure equation modeling (PLS-SEM) and partial least squares multi-group analysis (PLS-MGA). The results revealed that positive emotion toward SVSA directly influenced EI and purchase intention. EI and EPQ were identified as sequential mediators linking positive emotion toward SVSA and purchase intention. A finding for similarity in consumer response paths between social enterprises and CRM highlights that social enterprises need to develop a marketing strategy distinguished from CRM.

• Journal of Ginseng Research
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• 제24권3호
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• pp.118-122
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• 2000

식물조직배양기술을 이용하석 인삼의 주요약리성분인 사포닌을 생산하고자, 식물생장조절물질로 유도된 인삼 root를 사용하여 사포닌 생산을 위한 최적액체배양조건을 RSM으로 조사하였다. 최적액체배양조건을 배지의 pH, sucrose 농도,nitrogen 농도, phosphate 농도의 3 level-4 factor의 fractional factorial design에 의하여 조사한 결과, 인삼 root의 사포닌 함량은 최저 0.174%에서 최고 0.303울까지 나타났다. 다중회귀분석으로 구한 model식을 가지고 등고분석과 3차원분석을 수행한 후 독립변수의 최저 또는 최고수준에서 종속변수가 최대치를 나타내지 않는 phosphate농도 변수에 대하여 model식을 편미분한 결과 인삼 roe떠 사포닌 함량이 최고치를 나타내는 액체배양조건은 pH 5.5, sucrose 5%, nitrogen 50 mg/L, phosphate 93 mg/L 예측되었다. 이렇게 결정된 조건값들을 model식에 대입하여 얻은 예상치는0.308%였다.

• Journal of Ginseng Research
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• 제24권2호
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• pp.58-63
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• 2000

식물조직배양기술을 이용하여 인삼 root를 생산하고자, 식물생장조절물질로 유도된 인삼 root를 사용하여 최적액체배양조건을 RSM을 이용하여 조사하였다. 최적액체배양조건을 배지의 pH, sucrose 농도, nitrogen 농도, phosphate 농도의 3 level-4factor의 fractional factorial design에 의하여 조사한 결과, 인삼 root의 생장율은 최저 1.00g에서 최고 2.33g까지 나타났다. 다중회기분석으로 구한 model식을 가지고 등고분석과 3차원분석을 수행한 후 독립변수의 최저 또는 최고수준에서 조속변수가 최대치를 나타내지 않는 배지의 pH와 sucrose농도의 변수에 대하여 model식을 편미분한 결과 인삼 root의 최적액체배양조건은 pH5.6, sucrose 3.8%, nitrogen 50mg/L, phosphate 80.7mg/L로 예측되었다. 이렇게 결정된최적조건값들을 model식에 대입하여 얻은 예상치는 2.36g 이었다.

• Archives of Pharmacal Research
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• 제11권3호
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• pp.185-196
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• 1988

The inflence of hydrophilic vehicles on percutaneous absorption rate of griseofulvin was studied using intact skin of full thickness of hairless rat. The in vitro absorption rates were used as the characteristics for deciding the optimum formula of ointment vehicles. The optimum formula of vehicle compositions for maximum absorption rate was obtained from the polynomial regression equation and the two graphical techniques, contour graph and partial derivative graph. It was composed of sodium lauryl sulfate (1.65 W /W%), white petrolatum (16.5 W /W%), propylene glycol (12.0 W /W%), and stearyl alcohol (19.6W /W%). The experimental value obtained from the optimum formula and the prediction value were 33.99 and 33.87 ${\mu}g/\sqrt{min}$, respectively. From these results, it was believed that optimum formula for semisolid dosage forms could be obtained from the application of the optimization technique used in this study.

• Journal of Ginseng Research
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• 제18권1호
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• pp.53-59
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• 1994

To develop the methodology of the quantitative analysis of saponin in ginseng milk, conditions of the saponin extraction were optimized using the fractional factorial design with 3 variables and 3 levels by a RSM computer program. The extraction of saponin increased with an increase in extraction temperature up to $90^{\circ}C$ and then decreased significantly at $100^{\circ}C$. Extraction time affected the saponin yield in a similar trend. On the other hand, decreasing cooling temperature increased the amount of the saponin extracted. Recovery yield of the saponin from ginseng milk varied from 70.0% to 92.9%. The optimum extraction temperature, time and cooling temperature determined by partial differentiation of the model equation were $86^{\circ}C$, 2.83 hrs and $4^{\circ}C$, respectively. Key words Ginseng milk, saponin, response surface methodology.

• Advances in concrete construction
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• 제6권6호
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• pp.611-629
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• 2018

The objective of present study is to investigate the effect of granulated blast furnace slag (GBS) as partial substitution of natural sand on behaviour of cement mortar. For this, the methods of factorial design with water cement (w/c) ratio and incorporation percentages of GBS as replacement of natural fine aggregate i.e., GBS(%) as factors are followed. The levels of factor w/c ratio are fixed at 0.4, 0.45, and 0.5 and the levels of factor GBS(%) are kept fixed as 0%, 20%, 40%, 60%, 80% and 100%. The compressive strength (CS) of mortar after 3, 7, 14, 28, 56 and 90 days, and water absorption (WA) are chosen as responses of the study. Analysis of variance (ANOVA) of experimental results has been carried out and those are illustrated by ANOVA tables, main effect and interaction plots. The results of study depict that the selected factors have substantial influence on the strength and WA of mortar. However, the interaction of factors has no substantial impact on CS and WA of mixes.