• Korean Journal of Biological Psychiatry
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• v.7 no.1
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• pp.14-20
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• 2000

Recently atypical antipsychotics have been used as first line agent in the treatment of schizophrenia, and also played a significant role in the treatment of many kinds of psychiatric disorders. The pharmacokinetic and pharmacodynamic properties of these newer antipsychotics are well known through preclinical and early clinical trials. However, it is important to note the limitations of the results due to its relatively short experience. Clozapine is eliminated principally by the hepatic P450 1A2 and 3A4 cytochrome enzymes. 1A2 inducers such as carbamazepine and smoking can reduce its half-life, while 1A2 inhibitors such as SSRIs, especially fluvoxamine can increase its duration of action. Carbamazepine should be avoided in a patient on clozapine because of carbamazepine's potential effects on bone marrow. Benzodiazepines tend to increase the chances of sedation, delirium and respiratory depression. Risperidone is metabolized to 9-hydroxyriperidone by the hepatic P450 2D6 cytochrome enzymes. Fluoxetine and paroxetine, 2D6 inhibitors interfere with metabolism, but 9-hydroxyrisperidone has similar biological activity as parental drug, so it has little affect on the outcome. Olanzapine shows minimal capacity to inhibit cytochrome P450 isoenzymes and shows minimal chance of drug interaction. It is eliminated principally by the hepatic P450 1A2 and 2D6 cytochrome enzymes.

• International Journal of Human Ecology
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• v.12 no.2
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• pp.95-107
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• 2011

Recent intervention studies document that mother-child dyads with higher levels of Emotional Availability (EA) report fewer child behavior problems than dyads with lower EA. This study examines possible mechanisms that lead to this result by looking at the parent-child micro-system as a whole, with multi-dimensional relationships that include individual differences in the child's cognitive level, parental stress and parent-child interaction. A total 67 children ($1{\frac{1}{2}}$ to $5\;{\frac{1}{2}}$ years of age) and their mothers were videotaped during 30-min play interactions. Interactions were coded using the Emotional Availability (EA) Scales (Biringen, Robinson, & Emde, 1998). Mothers completed Parenting Stress Index-Short Form, Child Behavior Checklist/$1\;{\frac{1}{2}}$ - 5, and the Ages Stages Questionnaire. The findings showed that mothers with higher levels of parenting stress were more likely to be intrusive, hostile, insensitive, and had a tendency to do less structuring in play. The children of stressed and depressed mothers demonstrated less involvement and responsiveness towards their mothers. Children who have higher dyadic EA scores experienced fewer externalizing and internalizing problems. SEM analyses results showed a mediation effect of EA on the association between maternal psychological well-being and child behavior problems. Fewer deficits in child communication skills and problem solving skills that were related with lower parenting stress and depression were associated with higher maternal non-intrusiveness. Higher non-intrusiveness was related to less internalizing and externalizing problems that indicated the indirect effect of child cognitive competence. Possible interpretations and implications of the study findings are discussed.

• Korean Journal of Social Welfare
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• v.64 no.4
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• pp.5-29
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• 2012

This study aimed to express the experiences of the parents who lost their children by suicides in their own words from their own perspectives by van Manen(2000)'s hermeneutic phenomenological approach. The analysis of the words expressed by the research participants led to the following five fundamental themes. These are 'broken heart, sinner's grief, land of exile and time stood still, pains to be comforted, and days ahead with half-stitched wounds'. Several distinctions are found due to cultural differences from Korean parents. First, whereas the Western parents see the cause of their child's suicide as his/her independent issue, the Korean parents blame themselves entirely. This may have stemmed from the overly inter-dependency between the parents and the child. Second, whereas the Western perspective views the suicide as a type of illness from the individual's depression. The Korean perspective views the suicide as a shame that disgraces the parents or the family. This negative social perspective intensifies the self-blame and social isolation. Third, the Westerners recognize the prevention and responsibility of suicide resting with the society and government, but the Korean society recognize suicide as personal or family matter. Based on the finding above, I proposed a number of practical measures to aid the surviving parents who belong to a group with extremely high suicidal rates.

• Journal of the Korean Data and Information Science Society
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• v.26 no.2
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• pp.429-440
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• 2015

This study was to investigate factors influencing the school adjustment according to gender and body mass index (BMI) of middle school students who participated in the 2nd-wave Korea Children and Youth Panel Study (KCYPS). This study used a crosssectional design with secondary analysis with KCYPS. The variables were parental interest, behavioral problem, aggression, attention problem, somatic symptom, social withdrawal, depression, and academic achievement. The data were analyzed with descriptive statistics, Pearson's correlation coefficients, and multiple regressions. School adjustment was significantly associated with academic achievement high, explaining 11.3~19.1% of the variance in boys. School adjustment was significantly associated with attention problem, explaining 14.9~42.4% of the variance in girls. Factors influencing school adjustment were significantly different according to gender and BMI. To improve the school adjustment, it is necessary to develop gender-specific school adjustment promotion programs according to BMI.

• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.340-352
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• 2015

The purposes of this study is to analyze gender difference in predictors of mobile phone dependency in youth. The analysis is performed with third-year panel survey data of middle school 1st grade students from Korean Child-Youth Panel Survey. The results are as follows. First, the female students' mobile phone dependency is more serious than the male students' mobile phone dependency. Second, while the identified male gender predictors are aggression, parental abuse, aprosexia, study activity and social withdrawal, the identified female gender predictors are depression, aprosexia, aggression, study activity and social withdrawal. Based on these results, theoretical and practical implications in planning of prevention or intervention of mobile phone dependency are proposed.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.10 no.2
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• pp.195-200
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• 1999

Objective：This study was to investigate the effects of familial risk factors on the behavior problems of ADHD group and normal group. Method：The familial risk factors and behavioral problems of the children were administered to 160 mothers, comprised of 29 ADHD children and 131 normal children. Results：The results showed that the ADHD group and normal group were significantly different in the degree of marital satisfaction, state-trait anxiety, and depression. Familial risk factors and the behavior problems of children were significantly correlated. Conclusion：Marital unsatisfaction and parental affective problems were closely related to behavior problems of ADHD patients.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.22 no.4
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• pp.219-227
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• 2011

Objectives : This study examined maternal object relations, child's and mother's perception on rearing attitude, and children's self-esteem in children with attention-deficit hyperactivity disorder (ADHD) and their mothers. Methods : 64 children with ADHD and their mothers were included in the study group. In the control group, there were 85 children and their mothers. Mothers completed the following tests : Bell object relation inventory (BORI), maternal behavior research instrument (MBRI), Beck Depression Inventory (BDI), and Korean ADHD Rating Scale (K-ARS). Children completed Children's Report of Parental Behavior Inventory (CRPBI) and Rosenberg self-esteem scale. Results : Mothers of ADHD children displayed more rejecting and controlling parenting style than mothers in the control group. ADHD children showed lower self-esteem and perceived their parents as not affectionate, but rejecting and controlling. Mothers with ADHD children who belonged to object relations pathological group showed more rejecting rearing attitude and their children believed that they were more controlling, compared with children and mothers in other conditions. Among factors in mother's object relations, insecure attachment and ego-centricity impacted the rearing attitude. In turn, affective rearing attitude mainly influenced children's self-esteem. Conclusion : This study suggests that the approach focused on mother's object relations may help with the treatment of children with ADHD.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.9
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• pp.4368-4379
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• 2013

Purpose: The purpose of this study was to identify the factors that influence verbal abuse in early childhood mothers and to examine the fitness of a path model among these variables. The goal of the study was to provide fundamental data on ways in which verbal abuse by early childhood mothers can be prevented. Methods: The data was collected by using self report questionnaires from December 7th to 25th, 2011. The subjects were 320 early childhood mothers who had children in kindergarten. In order to estimate the hypothesized model, the data was analyzed using the AMOS 18.0 programs for structural equation modeling. Results: Parenting stress, anger and anger expression demonstrated a direct effect on causing verbal abuse by early childhood mothers. This study suggest that parental education program are necessary which a early childhood mothers can be express positively about parenting stress and anger.

• Journal of the Korea Convergence Society
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• v.13 no.4
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• pp.541-552
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• 2022

This study is a secondary data analysis study using the 1^st Panel Survey of School Dropouts in Korea for investigating predictors of suicide attempts in out-of-school youths (OSYs). Data analysis were performed using the SPSS 26.0 statistical program. Suicide attempts were reported in 62 (8%) of the 776 participants included in the study. Logistic regression analysis revealed that suicide attempts before school dropout (OR=10.66), experience of violence victimization (OR=6.97), alcohol consumption (OR=3.73), depression (OR=2.62), parental attachment (OR=0.47), peer relationships (OR=0.63) before school dropout were significant predictors of suicide attempts. Prevention of suicide attempts by OSYs should be preceded by confirmation of their experience in suicide attempts before school dropout. In addition, it is required to establish a suicide prevention program considering psychological situations, interpersonal relationships, and violence experiences.

• Korean Journal of Psychosomatic Medicine
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• v.30 no.2
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• pp.196-202
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• 2022

Objectives : The purpose of this study was to quantitatively assess the degree of Graves' Disease affecting mental health through the results of multiphasic military personality inventory (MPI) in 19-year-old men. Methods : We collected and analyzed the results of the MPI for 592 healthy subjects and 148 Graves' disease patients among the 19-year-old men who visited the Military Manpower Administration from February 2008 to January 2010. Results : Among demographic characteristics, both Graves' disease and control group are 19-year-old men. Educational level, socioeconomic status, parental relationship, and BMI were not statistically different between the two groups (χ²=0.089, p=0.766; χ²=5.090, p=0.278; χ²=5.988, p=0.112 ; t=-0.635, p=0.526). In the MPI, among validity scales, the score of the faking-good subscale was significantly lower in the Graves' group (t=3.507, p<0.001), but in the faking-bad and infrequency subscales scores were not significantly different between two groups (t=-1.700, p=0.090; t=-0.519, p=0.604). Among the neurosis scale, anxiety, depression, somatization, and personality disorder subscale scores were all significantly higher in Graves' disease group (t=-3.323, p<0.001; t=-4.210, p<0.001; t=-6.202, p<0.001; t=-2.872, p<0.01). Among the psychopath scale, each score of schizophrenia and paranoia subscales were not statistically different between the two groups (t=-0.158, p=0.874; t=-0.846, p=0.398). Conclusions : According to MPI result, we can confirm that Graves' disease patients in 19-year-old-men may appear features such as anxiety, depression, somatization and personality tendency (introversion or impulsivity) than the control group.