• Title/Summary/Keyword: Paraneoplastic polyneuropathy

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A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG (항 GD1b IgG 단일 항체와 관련된 길랭-바레 증후군으로 발현된 편평상피세포 폐암 증례)

  • Kim, Yeshin;Kim, Seongheon
    • Annals of Clinical Neurophysiology
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    • v.17 no.1
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    • pp.31-34
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    • 2015
  • We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient's symptoms improved.

Gastrointestinal Pseudoobstruction and Sensory Neuronopathy in Small Cell Lung Cancer (거짓 장막힘과 감각신경세포병증으로 발현된 소세포폐암 1예)

  • Lee, Hyun-Jeong;Choi, Young-Chul;Yun, Dong-Joo;Ko, Young-Chai;Jang, Sang-Hyun;Yoon, Soo-Jin;Oh, Gun-Sei;Lee, Soo-Joo
    • Annals of Clinical Neurophysiology
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    • v.13 no.2
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    • pp.106-110
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    • 2011
  • Subacute sensory neuronopathy and gastrointestinal pseudoobstruction are considered classical paraneoplastic neurological syndromes. We report a 56-year-old male who presented with typical symptoms of subacute sensory neuronopathy and autonomic neuropathy with gastrointestinal pseudoobstruction. The biopsy of the palpable supraclavicular lymph node revealed a small cell lung cancer. To our knowledge, intestinal pseudoobstruction and sensory neuronopathy in a small cell lung cancer have not been reported in Korea.

A Man Presenting with Sudden Weakness and Pain of the Right Hand, by Non-Small Cell Lung Cancer with Brain Metastases (비소세포폐암의 뇌전이로 인한 갑작스런 수부 통증 및 마비)

  • Sung, Won Jin;Hong, Bo Young;Kim, Joon Sung;Yoo, Jae Wan;Lim, Seong Hoon
    • Clinical Pain
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    • v.18 no.2
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    • pp.88-91
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    • 2019
  • Unexplained pain and weakness, i.e., without obvious predisposing factors, are often encountered by physiatrists and efforts should be made to determine the cause. A 63-year-old male presented with radiating pain in his right arm and mild weakness of the right hand. An electrodiagnostic examination revealed distal symmetric sensory polyneuropathy in the upper and lower extremities, and denervation potentials in the forearm muscles, which were inconsistent with the cervical spine MRI images and symptoms. A predisposing undiscovered disease was revealed, i.e., squamous cell carcinoma in the lung; brain metastasis affecting the left primary motor cortex was also detected. Therefore, we concluded that the pain and weakness were related to paraneoplastic syndrome and brain metastases of the hand knob. The observed denervation potentials were characterized as trans-synaptic changes in the brain metastasis. This case highlights the importance of unexplainable focal pain and weakness in the increasing prevalence of cancer.

Consideration of the Son-Bal Jeorim in oriental and western medicine (손발저림의 원인(原因)에 대(對)한 동서의학적(東西醫學的) 고찰(考察))

  • Park, Chi Young;Lim, Lark cheol;Kim, Young Il;Hong, Kwon Eui
    • Journal of Haehwa Medicine
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    • v.13 no.1
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    • pp.47-59
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    • 2004
  • Objectives & Methods: We investigated 28 books to study etiology and pathology of Son-Bal Jeorim. Result and Conclusion 1. The eiology of Son-Bal Jeorim is same as it of Bee Jeung(痺症). 2. Generally speaking, the cause of Bee Jeung was distributed Wind(風), Coldness(寒), Wetness (濕) of meridian. Bee Jeung can be devided into SilBi(實痺) and HeoBi(虛痺). In SilBi(實痺) there are PungHanSeupBi(風寒濕痺) and YeolBi(熱痺). In HeoBi(虛痺), there are GiHyeolHeoBi(氣血虛痺), EumheoBi(陰虛痺) and YangHeoBi(陽虛痺). 3. Son-Bal Jeorim belong to peripheral neuropathy in western medicine. 4. Syndrome of acute motor paralysis with variable disturbance of sensory and autonomic function, subacute sensorymotor paralysis, syndrome of chronic sensorimotor polyneuropathy, neuropathy with mitochondrial disease, syndrome of mononeuropathy or nerve plexusopathy. 5. Peripheral neuropathy is caused by carpal tunnel syndrome, diabetic neuropathy, uremic neuropathy, hepatic neuropathy, hypothyroid neuropathy, hyperthyroid neuropathy, neuropathy due to malnutrition, neuropathy due to toxic material, neuropathy due to drug, paraneoplastic neuropathy, hereditary neuropathy, etc. 6. Cerebral apoplexy, myelopathy, peripheral circulatory disturbance, anxiety syndrome cause symptoms of peripheral neuropathy

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