Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG

항 GD1b IgG 단일 항체와 관련된 길랭-바레 증후군으로 발현된 편평상피세포 폐암 증례

  • Kim, Yeshin (Department of Neurology, Kangwon National University School of Medicine) ;
  • Kim, Seongheon (Department of Neurology, Kangwon National University School of Medicine)
  • 김예신 (강원대학교 의과대학 신경과학교실) ;
  • 김성헌 (강원대학교 의과대학 신경과학교실)
  • Received : 2014.11.26
  • Accepted : 2015.06.03
  • Published : 2015.06.30
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Abstract

We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient's symptoms improved.

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References

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