• Journal of Acupuncture Research
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• v.25 no.3
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• pp.139-162
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• 2008

Objectives : Korean tradithional acupuncture Theory, Sa-am's 5 phases acupuncture method was originated in 1644-1742, in the middle of the Cho Sun dynasty. This study was to vertify the effect of Sa-am Acupuncture Treatment on Primary dysmenorrhea of Women. Methods : The subjects were 80 volunteers who was suffering for dysmenorrhea, employed using Measure of Menstrual Pain (MMP) questionnaire. Subjects were divided into two groups including Sa-am acupuncture treatment group(n=25), minimal acupuncture treatment group(n=22). They had agreed to take part in this experiment, with didn't take any anodyne drugs. In the acupuncture group, subjects were stimulated at G41, $SI_3$, B66, $SI_2$(Small intestine jung-guk), $SP_6$, $CV_6$ and one points were inserted additionally depending the symptoms among $ST_{36}$ or $LI_2$. In the control group, subjects were needled at 5 non-acupuncture points have any effect on Dysmenorrhea. A total of 8 acupuncture sessions were performed for each patient depending on the individual menstruation cycle The MMP score by using 7 questions and the Menstrual Symptom Severity List(MSSL-D) was measured before and after menstruation cycle. Collected data were analyzed as frequency, percentage, paired t-test, independent t-test using SPSS 10.0 WIN Program. Results : Acupuncture treatment produced a significant decreasing the symptom of Primary dysmenorrhea in two groups, but a statistically significant difference was not shown in the acupuncture group compare to control group. Conclusions : Based on the above results, it was verified that Acupuncture Treatment was effective in decreasing the symptom of Primary Dysmenorrhea.

• Journal of Acupuncture Research
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• v.24 no.3
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• pp.63-79
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• 2007

Objectives : Korean traditional acupuncture Theory, Sa-am's 5 phases acupuncture method was originated in 1644-1742, in the middle of the Cho Sun dynasty. This study was to verify the effect of Sa-am Acupuncture Treatment on dysmenorrhea of Women. Methods : The subjects were 49 volunteers who were suffering for dysmenorrhea, employed using Measure of Menstrual Pain (MMP) questionnaire. Subjects were divided into two groups including Sa-am acupuncture treatment group(n=23) and minimal acupuncture treatment group(n=26). They had agreed to take part in tIris experiment, with didn't take any anodyne drugs. In the acupuncture group, subjects were stimulated at $GB_{41}$, $SI_3$, $GL_{66}$, $SI_2$(Small intestine jung-guk) and $SP_6$. In the control group, subjects were needled at $L_{10}$, $S_{40}$, $P_5$, $G_{40}$ points have any effect on dysmenorrhea. A total of 5 acupuncture sessions were performed for each patient depending on the individual menstruation cycle. The MMP score by using 7 questions and the Menstrual Symptom Severity List(MSSL-D) were measured before and after menstruation cycle. Collected data were analyzed as frequency, percentage, paired t-test, independent t-test using SPSS 10.0 WIN Program. Results : Acupuncture treatment produced a significant improvement on dysmenorrhea in two groups, but a statistically significant difference was not shown in the acupuncture group compare to control group. Conclusions : Based on the above results, it was verified that Acupuncture Treatment was effective in decreasing the symptom of Dysmenorrhea.

• Journal of Sasang Constitutional Medicine
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• v.28 no.4
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• pp.330-337
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• 2016

Objectives The purpose of this study was to investigate whether the menstrual pain affect the Sasang constitutions questionnaire response in adult women. Methods Using a structured menstrual history questionnaire, we evaluated the degree of menstrual pain of 550 adult women who participated in this clinical trial. Based on the survey we classified them into menstrual pain group and control group. They filled out SSCQ-P (Sasang Constitution Questionnaire for Patients) and we had compared the difference in response by Sasang constitutions. From 329 women in menstrual pain group and 212 women in control group, 541 questionnaire was analyzed statistically by their constitutions. Results 7 questions in Soyangin, 11 questions in Taeeumin and 20 questions in Soeumin were statistically significant in response between menstrual pain group and control group. Conclusions Soyangin's menstrual pain shows less influence on SSCQ-P than Taeeumin and Soeumin. Taeeumin who has Taeyangin's appearances and characteristics has more menstrual pain. In Soeumin, menstrual pain may result in negative and less expressive characteristics.

• The Korea Journal of Herbology
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• v.35 no.6
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• pp.55-68
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• 2020

Objectives : We observed the possibilities that blue honeysuckle has favorable analgesic or refinement effects on the Primary dysmenorrhea (PD) in rats. Methods : Estradiol benzoate and oxytocin were used to induce the PD rat model. And Blue honeysuckle concentration lyophilized powders (BH) 500, 250 and 125 mg/kg and 500 mg/kg of Lonicerae Flos aqueous extract lyophilized powders (LF) were orally administered, once a day for 10 days at 30 min after each estradiol benzoate treatment. Then the changes on the body weights and gains during experimental periods, abdominal writhing response for analgesic activities, uterine weights, uterus lipid peroxidation, antioxidant defense system - glutathione contents, superoxide dismutase and catalase activities, NF-κB and COX-2 mRNA expressions were monitored with uterus histopathology including immunohistochemistry for tumor necrosis factor (TNF)-α and inducible nitric oxide synthase (iNOS).. Results : Inflammatory and oxidative stress mediated PD signs were favorably and dose-dependently inhibited by 10 days continuous oral administration of three different dosages of BH - 500, 250 and 125 mg/kg as comparable to those of indomethacin(IND) 5 mg/kg treated rats in BH 500 mg/kg administered PD rats, and similar to those of LF 500 mg/kg in BH 125 mg/kg, at least in a condition of the present PD rat model. Conclusions : The results suggest that BH has favorable analgesic and refinement activities on the estradiol benzoate and oxytocin treatment-induced PD signs through anti-inflammatory and antioxidative potentials.

• Journal of Korean Public Health Nursing
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• v.28 no.2
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• pp.187-199
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• 2014

Purpose: The purpose of this study was to investigate the effects of SP-6 Seoam pellet therapy given to female university students in terms of menstrual pain, menstrual distress, and ADL difficulties. Methods: This study used a pre-test, post-test design with a nonequivalent control group. The participants were 68 female students in two universities. The experimental group(n=34) received Seoam pellet therapy at Sanyinjiao while the control group(n=34) received sham therapy. Data were collected from Sep. 16 to Nov. 30, 2012. Severity of menstrual pain, menstrual distress, and difficulty of ADL were assessed prior to and following treatment. Independent t-test, $x^2$ test, and repeated measures ANOVA were used for examination of group differences using the SPSS/WIN program. Results: Severity of menstrual pain (F=41.09, p<.001), menstrual distress (F=56.31, p<.001), and ADL difficulties (F=46.64, p<.001) showed a significant decrease in the experimental group compared to the control group. Conclusion: Results indicate that this Seoam pellet therapy is effective in reducing menstrual pain, menstrual distress, and difficulty of ADL. Therefore, use of this method is recommended for relief of menstrual pain and menstrual distress through self-care.

• Clinical and Experimental Reproductive Medicine
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• v.50 no.4
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• pp.223-229
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• 2023

Endometriosis is characterized by the implantation of endometrial cells outside the uterus. This hormone-dependent disease is highly prevalent among women of reproductive age. Clinical symptoms of endometriosis include dysmenorrhea, pelvic pain, and infertility, which can negatively impact the overall quality of life of those affected. The medical treatment of endometriosis serves as an important therapeutic option, aimed at alleviating pain associated with the condition and suppressing the growth of endometriotic lesions. As such, it is employed as an adjuvant therapy following surgery or an empirical treatment after the clinical diagnosis of endometriosis. Dienogest, a fourth-generation progestin, has received approval for the treatment of endometriosis in many countries. A growing body of evidence has demonstrated its efficacy in managing endometriosis-associated pain, preventing symptoms, and reducing lesion recurrence. In this review, we examine the clinical efficacy, safety, and tolerability of dienogest in treating endometriosis. We also provide updated findings, drawing from clinical studies that focus on the long-term use of this medication in patients with endometriosis.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.3
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• pp.157-164
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• 2014

Objectives The purpose of this study is to evaluate the effects of chuna with and without acupuncture, and compare the effect of both group by VAS (visual analogue scale) and Cox menstrual symptom scale. Methods This study was carried out on 24 dysmenorrhea patients. 24 patients were divided into single treatment group(Group A) and combined treatment group (Group B). Group A treated with chuna. Group B treated with chuna and acupuncture. After performing chuna and acupuncture 8 weeks, we compared both in terms of VAS and Cox menstrual symptom scale. Results 1) Both group A and group B showed significant improvement in abdominal pain and lumbago after treatment. 2) Both group A and group B showed significant improvement in Cox menstrual symptom scale for both frequency and severity after treatment. 3) There were no significant differences between both groups. Conclusions According to above results, we found out that performing chuna with and without acupuncture has effect in terms of VAS and Cox menstrual symptom scale. But, we can't found out difference between single treatment and combined treatment.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.1
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• pp.150-167
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• 2008

Purpose: This is a following study of preceding study about application and improvement of acupuncture benefits in OB & GY disease that was performed in 2007. And this study was performed to complement and compare with a preceding study. Methods: The questionnaire used in preceding survey was distributed to general korean medical doctors who have mainly worked in oriental medical clinic. And results of this survey was compared with results of preceding survey. Results: Results of two surveys were almost similar. 1. The common suitable the sick and wounded name of Ob & Gy disease thought be added in Intra-abdominal acupuncture(腹腔內; CV13 ${\cdot}$ CV16 ${\cdot}$ CV10) in two surveys were dysmenorrhea(K05). infertility(K15), JingHa(pelvic tumor) (K11). In Puncture each adjoining acu-points in one insertion(透刺; SP6-GB39)were dysmenorrhea(K05), climacteric syndrome(K04). amenorrhea (K03), In Puncture each adjoining acu-points in one insertion(透刺; PC6-TE5) were climacteric syndrome(K04), hyperemesis(K16.0), dysmenorrhea(K05). 2. The common acupuncture benefits items that postpartum pain syndrome(K29) should be added as suitable the sick and wounded name were Intra-articular acupuncture(關節內; LI15, SI10, GB30), Intervertebral acupuncture (脊椎間; GV14, 16, 6, 4, 12, 11, 9, 8, 3), Puncture each adjoining acu-points in one insertion (透刺; SP6-GB39). Conclusion: Based on this study, Survey to more KMDs should be performed. And the academic and clinical verifications that supports this results should be supplied.

• Journal of Acupuncture Research
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• v.39 no.3
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• pp.182-189
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• 2022

To evaluate the effectiveness of electroacupuncture treatment for primary dysmenorrhea (PD), a literature review of a randomized controlled trials (RCTs) was performed where electroacupuncture was used as a treatment intervention in patients diagnosed with PD. Relevant clinical studies (N = 226) were retrieved from multiple databases according to the study inclusion/exclusion criteria, and interventions and outcomes were analyzed. As a result of the review, there were 6 RCTs which met the criteria. In all 4 studies that measured pain indicators (visual analog scales), electroacupuncture showed significantly positive changes. In addition, positive changes were observed in most indicators (MMDQ, PGF2a, PGE2, 6-keto PGF1, TXB2, clinical efficacy score, uterine arterial blood flow parameters, and blood viscosity). 2 studies showed that electroacupuncture had a stronger therapeutic effect than NSAIDs. No major side effects were reported. Electroacupuncture may be an effective and safe treatment for PD however, further RCTs are required.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.29 no.3
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• pp.85-99
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• 2023

Background: This study aimed to investigate the effects of a complex manual therapy program on hip and knee pain occurring together with menstrual pain and iliotibial band tightness in a woman with sacroiliac joint dysfunction. Methods: This study was carried out over a period of 3 months by dividing the treatment process into three sequential stages. Intensities of menstrual pain, hip pain, and knee pain, and hip range of motion (ROM) in the participant were assessed at baseline and at the end of each stage, and a modified intervention was applied according to results of assessments after each stage. Results: There was a decrease in the intensity of menstrual pain after the first and third stages of treatment, and there were reductions in the intensities of hip and knee pain after the third stage. Hip ROM was rather decreased after the second stage, but it was increased after the third stage. Conclusion: The findings of this study indicate that treatment of the instability and positional fault of sacroiliac joint can relieve hip and knee pain, improve hip ROM, and alleviate primary dysmenorrhea in patients with sacroiliac joint dysfunction.