• 제목/요약/키워드: Pain, intractable

검색결과 200건 처리시간 0.033초

Microvascular Decompression for Glossopharyngeal Neuralgia : Clinical Analyses of 30 Cases

  • Kim, Mi Kyung;Park, Jae Sung;Ahn, Young Hwan
    • Journal of Korean Neurosurgical Society
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    • 제60권6호
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    • pp.738-748
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    • 2017
  • Objective : We present our experience of microvascular decompression (MVD) for glossopharyngeal neuralgia (GPN) and evaluate the postoperative outcomes in accordance with four different operative techniques during MVD. Methods : In total, 30 patients with intractable primary typical GPN who underwent MVD without rhizotomy and were followed for more than 2 years were included in the analysis. Each MVD was performed using one of four different surgical techniques : interposition of Teflon pieces, transposition of offending vessels using Teflon pieces, transposition of offending vessels using a fibrin-glue-coated Teflon sling, and removal of offending veins. Results : The posterior inferior cerebellar artery was responsible for neurovascular compression in 27 of 30 (90%) patients, either by itself or in combination with other vessels. The location of compression on the glossopharyngeal nerve varied; the root entry zone (REZ) only (63.3%) was most common, followed by both the REZ and distal portion (26.7%) and the distal portion alone (10.0%). In terms of detailed surgical techniques during MVD, the offending vessels were transposed in 24 (80%) patients, either using additional insulation, offered by Teflon pieces (15 patients), or using a fibrin glue-coated Teflon sling (9 patients). Simple insertion of Teflon pieces and removal of a small vein were also performed in five and one patient, respectively. During the 2 years following MVD, 29 of 30 (96.7%) patients were asymptomatic or experienced only occasional pain that did not require medication. Temporary hemodynamic instability occurred in two patients during MVD, and seven patients experienced transient postoperative complications. Neither persistent morbidity nor mortality was reported. Conclusion : This study demonstrates that MVD without rhizotomy is a safe and effective treatment option for GPN.

거골 골절 탈구 후 무혈성 괴사의 장기 추시: 5예 (Long Term Follow-up of Avascular Necrosis after Talar Fracture and Dislocation: 5 Cases)

  • 김병철;최성종;김휘택;류총일;정성원;은일수;구정모;김종균
    • 대한족부족관절학회지
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    • 제9권1호
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    • pp.31-37
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    • 2005
  • Purpose: To report our opinions of management about avascular necrosis following operative treatment of talar fracture and dislocation. Materials and Methods: We followed up 5 patients who were diagnosed as talar avascular necrosis after operation of talar fracture and dislocation. Clinical and radiological analysis were performed. The mean age of patients was 36 years. There were 4 males and 1 females. The average follow up was 51 months. Hawkins scoring system was used as clinical evaluation. Results: Regardless of radiological sclerotic finding, all patients showed satisfactory clinical result. Despite arthritic change in one patient, there were no further radiological and clinical deterioration to require salvage procedure. Conclusion: Most avascular necrosis after operative treatment of talar fracture and dislocation showed satisfactory result with conservative treatment. Thus, salvage operation such as talectomy or ankle fusion should be reserved in cases of intractable ankle pain and claudication.

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Advanced Gastric Cancer Associated with Disseminated Intravascular Coagulation Successfully Treated with 5-fluorouracil and Oxaliplatin

  • Lee, Dong Seok;Yoo, Seung Jin;Oh, Ho Suk;Kim, Eun Jung;Oh, Kwang Hoon;Lee, Sang Jin;Park, Jong Kyu;Ahn, Yong Chel;Eom, Dae-Woon;Ahn, Heui June
    • Journal of Gastric Cancer
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    • 제13권2호
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    • pp.121-125
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    • 2013
  • Gastric cancer patients with acute disseminated intravascular coagulation experiences a rare but severe complication resulting in a dismal prognosis. We report a case of advanced gastric cancer complicated with disseminated intravascular coagulation with intractable tumor bleeding which was successfully treated with chemotherapy consisting of 5-fluorouracil and oxaliplatin. The patient was a 63-yearold man who complained of abdominal pain, melena, and dyspnea on 24 November 2010. We diagnosed stage IV gastric cancer complicated by disseminated intravascular coagulation. Gastric tumor bleeding was not controlled after procedures were repeated three times using gastrofiberscopy. With the patient's consent, we selected the 5-fluorouracil and oxaliplatin combination chemotherapy for treatment. After one cycle of 5-fluorouracil and oxaliplatin therapy, symptoms of bleeding improved and the disseminated intravascular coagulation process was successfully controlled. The primary tumor and multiple metastatic bone lesions were remarkably shrunken and metabolically remitted after eight cycles of chemotherapy. In spite of progression, systemic chemotherapy is effective in disease control; further, the patient gained the longest survival time among cases of gastric cancer with disseminated intravascular coagulation.

중엽증후군 (Middle Lobe Syndrome)

  • 이용훈;김병철
    • Journal of Chest Surgery
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    • 제29권6호
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    • pp.621-625
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    • 1996
  • "중엽증후군"의 용어는 Grahaml)등에,의해 처음 기술되어졌으며 대개 비후된 림프절에 의해 기관지 가 외부적으로 압박되 어 발생된다고 하였다. 환자들은 거의 증상이 없을 수 있으나 가장 흔한 발현 증상 은 기침, 호흡 곤란, 반복되는 발열, 객혈, 그리고 흥통 등이다. 진단방법은 흉부 X선, 기관지경검사, 기 관지조영술, 흉부컴퓨터단층될영 등이며 대개 공기가 없이 압축된 중엽이 중요한 소견이다. 본 저자들은 1990년 3월에서 1995년 5월까지 15례의 중엽증후군을 경 험하였으며 그 중 11례에서 수술 적 치료를 시행하였다. 중엽 증후군의 환자에서 수술적용은 악성 종양이 의심되거나,비가역적 기관지 확장증,기관지협착증,약물 치료에 호전이 없는 경우, 치료후 반복되는 감염 등의 경우에 시행하였다. 수술은 중엽절제술 8례,중엽 및 하엽절제술2례,상엽 및 중엽절제술 1례를시술하였다. 수술후 병리조 직소견상 결핵 6례, 만성감염 3례, 악성 종양 1례, 국소적 출혈 1례의 소견을 보였다 술후 합병증은 2례에서 발생하였으며,그 중 1례에서 술후 폐허탈, 1례에서 간장장애를 경험하였으며 치유되었다.였으며 치유되었다.

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Analysis of Sternal Fixation Results According to Plate Type in Sternal Fracture

  • Byun, Chun Sung;Park, Il Hwan;Hwang, Wan Jin;Lee, Yeiwon;Cho, Hyun Min
    • Journal of Chest Surgery
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    • 제49권5호
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    • pp.361-365
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    • 2016
  • Background: Sternal fractures are relatively rare, and caused mainly by blunt anterior chest wall trauma. In most cases, sternal fractures are treated conservatively. However, if the patient exhibits problematic symptoms such as intractable chest wall pain or bony crepitus due to sternal instability, surgical correction is indicated. But no consensus exists regarding the most appropriate surgical method. We analyzed the results of surgical fixation in cases of sternal fracture in order to identify which surgical method led to the best outcomes. Methods: We retrospectively reviewed the medical records of patients with sternal fractures from December 2008 to December 2011, and found 19 patients who underwent open reduction and internal fixation of the sternum with a longitudinal plate (L-group) or a T-shaped plate (T-group). We investigated patients' characteristics, clinical details regarding each case of chest trauma, the presence of other associated injuries, the type of open reduction and fixation, whether a combined operation was performed, and postoperative complications. Results: Of the 19 patients, 10 patients (52.6%) were male, and their average age was 56.8 years (range, 32 to 82 years). Seven patients (36.8%) had isolated sternal fractures, while 12 (63.2%) had other associated injuries. Seven patients (36.8%) were in the L-group and 12 patients (63.2%) were in the T-group. Three patients in the L-group (42.9%) showed a loosening of the fixation. In all patients in the T-group, the fracture exhibited stable alignment. Conclusion: Open reduction and internal fixation with a T-shaped plate in sternal fractures is a safer and more efficient treatment method than treatment with a longitudinal plate, especially in patients with a severely displaced sternum or anterior flail chest, than a longitudinal plate.

영아에서 간담도 스캔으로 진단된 총 담관낭의 자연 천공에 의한 담즙성 복막염 1례 (Bile Peritonitis Due to Spontaneous Rupture of Choledochal Cyst Diagnosed by Hepatobiliary Scintigraphy in an Infant)

  • 김종석;임장훈;배상남;이준우;김인주;박재홍
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제5권2호
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    • pp.186-191
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    • 2002
  • 구토, 심한 보챔, 고열, 복수를 동반한 복부 팽만 등 급성 복막염의 양상을 보인 10개월 된 여아에서 복부 천자 후 담즙성 복막염 의심하에 $^{99m}Tc$ DISIDA 간담도 스캔을 시행하여 진단된 총 담관낭의 자연 천공에 의한 담즙성 복막염 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

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삼차신경통에 대한 사이버나이프 방사선수술의 조기 치료 효과 (Early Therapeutic Effects of Cyberknife Radiosurgery on Trigeminal Neuralgia)

  • 문성권;최일봉;강영남;장지선;강기문;최병옥
    • Radiation Oncology Journal
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    • 제24권2호
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    • pp.88-95
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    • 2006
  • 목적: 삼차신경통 환자에서 사이버나이프 방사선수술이 효과적이며 안전한 치료방법인지 알아보고자 하였다. 대상 및 방법: 2004년 3월부터 2005년 5월까지 수술 후 실패하였거나 수술이 부적합한 삼차신경통 환자 26명을 대상으로 사이버나이프 방사선수술을 시행하여 후향적 분석을 하였다. 치료 표적은 삼차신경근 진입구역으로부터 3 mm 떨어진 지점의 삼차신경 최고 근위부를 제외한 6 mm 길이의 삼차신경 부위를 설정하고, 그 부위에 80% 등선량 곡선에 단일 조사로 총방사선량은 $60{\sim}64Gy$를 조사하였다(중앙선량: 64 Gy). 결과: 추적관찰기간은 $3{\sim}15$개월이었다(중앙추적관찰기간 : 9개월). 대상환자 26명에서 사이버나이프 방사선수술 후 24시간 이내에 50% (13/26)에서 통증 완화를 관찰하였으며. 7일 이내에 조기 통증 완화를 보였던 환자는 96.2% (25/26)이었다. 치료 실패는 7.7% (2/26)에서 나타났으며 통증 개선 실패와 통증 재발이 각각 1명에서 관찰되었다. 치료 부작용으로 안면감각 감퇴가 11.5% (3/26)에서 관찰되었다. 결론: 삼차신경통 환자를 대상으로 사이버나이프 방사선수술을 시행한 예비 결과로 비교적 안전하며, 효과적인 치료임을 확인하였다.

성상신경절 차단과 전기침 자극에 의한 알레르기성 비염의 치료 (Stellate Ganglion Block and Electrical Acupuncture for Treatment of Allergic Rhinitis)

  • 김진승;진성미;조성경;김봉일;이상화
    • The Korean Journal of Pain
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    • 제6권2호
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    • pp.208-212
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    • 1993
  • 1990년 5월부터 1993년 4월까지 알레르기성 비염으로 대구가톨릭대학 병원 통증치료실을 방문한 환자를 대상으로 하여 SGB와 E-AP로 병용 치료 하였는바 2회 이상 시행한 49명을 본 대상으로 하여 회고적으로 관찰하였다. 나이는 7세에서부터 70세까지로 평균 34.1세 였으며, 연령별로는 41~50세 사이가 많았으며, 내원 계절별로는 가을과 여름 순으로 많았다. SGB의 평균 시행 횟수는 $6.02{\pm}4.29$회였고, E-AP의 평균 시행 횟수는 $7.15{\pm}5.57$회였다. 환자의 병력은 평균 $5.53{\pm}7.10$년 이었으며, 1주일에서 30년까지 다양하였다. 6개월 이하의 병력시 SGB의 평균 시행 횟수가 $3.13{\pm}1.81$회로 6개월 이상 병력시의 평균 시행 횟수 $6.51{\pm}4.40$회 보다 통계적으로 의의있게 적었으며, 또한 치료기간도 6개월 이상 병력시의 $49.67{\pm}37.30$일 보다 6개월 이하 병력시의 $18.00{\pm}14.88$ 일이 통계적으로 의의있게 짧았다. 24명의 남자중 1명이, 25 명의 여자중 1명이 재발 내원하여 재 치료하였다. 치료 도중에 1명의 남자와 1명의 여자에게서 연하곤란증이 있었고, 1명의 여자에게서 4~5시간의 애성이 있었으나 그 후 정상으로 회복되었다. 본 질환은 일단 발병 하게되면 그 원인 규명도 어려울 뿐만 아니라 치료 역시 재발 악화 등 개운치 않은 질환인데도 전기침자극과 국소마취제에 의한 성상신경절 차단등 비교적 간단한 방법으로 매우 효과적인 반응을 얻게 되어 향후 널리 보급될 것으로 사료된다.

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내장신경차단에 관한 임상적 연구 (A Clinical Evaluation of Splanchnic Nerve Block)

  • 김수연;오흥근;윤덕미;신양식;이윤우;김종래
    • The Korean Journal of Pain
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    • 제1권1호
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    • pp.34-46
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    • 1988
  • Intractable pain from advanced carcinoma of the upper abdomen is difficult to manage. One method used to control pain associated with these malignancies is to block off the splanchnic nerve. In 1919 Kappis described a technique by which the splanchnic nerve of the upper abdomen could be anesthetized, using a percutaneous injection. This method has been used for the relief of upper abdominal pain due to hematoma and cancer of the pancreas, stomach, gall bladder, bile duct, and colon. During the Period from November 1968 to January 1986, this method was used in 208 cases of malignancy at Severance Hospital and clinically evaluated. Patients were retroactively grouped according to the stage of development of technique used. Twelve patients who received the treatment in the period from November 1968 to March 1977 were designate4i as group 1, 26 patients from April 1977 to April 1979 as group 2, and 170 from May 1979 to January 1986 as group 3. The results are as follows: 1) The number of patients receiving splanchnic nerve block has been increasing since 1977. 2) A total of 208 patients, including 133 males and 75 females, ranging in age from 18 to 84 and averaging 51. 3) The causes of pain were stomach cancer 90, pancreatic cancer 69, and miscellaneous cancer 49 cases respectively. 4) There were 57.7% who had surgery. and 3.7% of whom had chemotherapy before the splanchnic nerve block was done. 5) These blocks were carried out with the patient in the prone position as described by Dr. Moore. For group 2 and 3, C-arm image intensifier was used. In group 1, a 22 gauze loom long needle was inserted at the lower border of the 12th rib on each aide about 7\;cm from the midline. The average distance from the midline was $6.60{\pm}0.61\;cm$ on the left side and $6.60{\pm}0.83\;cm$ on the right side in group 2, and $5.46{\pm}0.76\;cm$ on the left side and $5.49{\pm}0.69\;cm$ on the right side in group 3. The average depth to which the needle was inserted was $8.60{\pm}0.52\;cm$ on the left side and $8.74{\pm}0.60\;cm$ on the right side in group 2, and $8.96{\pm}0.63\;cm$ on the left side and $9.18{\pm}0.57\;cm$ on the right side in group 3. 6) The points of the inserted needles were positioned in the upper quarter anteriorly, 51.8% on the left side and 54.4% n the right side of the L1 vertebra by lateral roentgenogram in group 3. The inserted needle points were located in the upper and anterolateral part, of the L1 vertebra 68.5% on the left side and 60.6won the right side, on the anteroposterior rentgenogram in group 3. The needle tip was not advanced beyond the anterior margin of the vertebral body. 7) In some case of group 3, contrast media was injected before the block was done. It shows, the spread upward along the anterior mal gin of the vertebral body. 8) The concentration and the average amount of drug used in each group was as follows: In group 1, $39.17{\pm}6.69\;ml$ of 0.5% -l% lidocaine or 0.25% bupivacaine were injected for the test block and one to three days after the test block $40.00{\pm}4.26\;ml$ of 50% alcohol was injected for the semipermanent block. In group 2, $13.75{\pm}4.88\;ml$ of 1% lidocaine were used as the test block and followed by $46.17{\pm}4.37\;ml$ of 50% alcohol was injected as the semipermanent block. In group 3, $15.63{\pm}1.19\;ml$ of 1% lidocaine for test block followed by $15.62{\pm}1.20\;ml$ of pure alcohol and $16.05{\pm}2.58\;ml$ of 50% alcohol for semipermanent block were injected. 9) The result of the test block was satisfactory in all cases. However the semipermanent block was 83.3 percent of the patients in group 1 who received relief from pain for at least 2 weeks after the block, 73.1% in group 2, and 91.8% in group 3. In these unsuccessful cases, 2 cases in group 1 were controlled by narcotics but 7 cases in group 2 and 14 cases in group 3 received the same splanchnic nerve block 1 or 2 times again within 2 weeks. But, in some cases it was 3 to i months before the 2nd block and in 1 cases even 7 years. 10) The most common complications of splanchnic nerve block were hypotensino(25.5%) occasional flushing of the face, nausea, vomiting, and chest discomfort. 11) For the patients in group 3, the supplemental block most commonly used was a continuous epidural block; it was used as a diagnostic block and to afford relief from pain before the splanchnic nerve block was done. 12) The interval between the receiving of the alcohol block and discharge was from 5 to 8 days in 61 cases(31.1%) and from 1 to 2 days in 48 cases(24.5%). From the above results, it can be concluded that the splanchnic nerve block done in the prone position with pure and 50% alcohol immediately after an effective test block with 1% lidocaine under C-arm fluoroscopic control is satisfactory and reliable. How to minimize the repeat block is still a problem to be solved.

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삼차신경통의 임상 소견과 약물 치료에 관한 연구 (A Study on Clinical Features and Pharmacologic Treatment Outcomes of Patients with Trigeminal Neuralgia)

  • 고유정;김균요;허윤경;최재갑
    • Journal of Oral Medicine and Pain
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    • 제34권2호
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    • pp.207-216
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    • 2009
  • 2003년부터 2008년까지 경북대학교병원 구강내과를 내원한 삼차신경통 환자 90명의 임상 소견 및 약물 치료에 대한 결과를 분석하여 다음과 같은 결론을 얻었다. 1. 삼차신경통 환자는 40대 이상이 94.4%를 차지하였고 남녀비가 1:2.1로 여성에서 거의 2배 정도 호발하였다. 2. 삼차신경의 상악분지에 단독으로 이환된 경우가 51.1%로 가장 많았고 좌우비가 1:2.9로 우측에 더 자주 발생하였다. 3. 85명(94.4%)의 환자가 경북대학교병원 구강내과에 내원하기 전 삼차신경통을 치료하기 위해 다른 의료기관을 내원한 경험이 있었다. 3. 40명(44.4%)의 환자가 현재 치료 중인 전신질환을 가지고 있었다. 4. Carbamazepine 단독 투여로 69명(76.7%)의 환자가 효과를 나타내었으며 이 때 사용된 Carbamazepine의 일일 용량은 평균 402.9mg이었다. 반면에 16명(17.8%)의 환자는 Carbamazepine과 다른 약물을 복합 투여하여 효과를 나타내었고 사용된 Carbamazepine 일일 용량은 평균 618.8mg이었으며 가장 많이 사용된 병용 약물은 Baclofen이었다. 나머지 5명(5.6%)의 환자는 Carbamazepine으로 효과를 얻지 못했다. 5. Carbamazepine 단독 투여에 효과가 있었던 69명 중 39명은 내원 기간 동안 지속적인 효과를 나타내었으나 30명은 Carbamazepine에 대한 효과가 감소하였거나 부작용으로 인해 복합 투약을 시행하였거나 다른 약물로 교체 또는 신경외과로 의뢰하였다. 6. 54명(60%)의 환자에서 Carbamazepine 투여 후 현기증, 졸음, 오심, 혈구 감소, 피부 발진 등의 부작용이 발생하였으나 대부분 그 정도가 미약하거나 일시적이었고 11명의 환자가 부작용으로 인해 Carbaamzepien 투약을 중단하였다.