• Korean Journal of Fisheries and Aquatic Sciences
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• v.54 no.2
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• pp.162-169
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• 2021

Global warming has affected the distribution of organisms for decades and has displayed rapid ascent recently. Research into the effects on tropical organisms are vital. Padina boryana is a resourceful marine microalgae in the Maldives Sea in the Laccadive region. A 70% ethanol extraction (PBE) of this seaweed was used to investigate its antioxidant potential. Both in vitro and in vivo models were implemented. PBE exhibited protective potential against H₂O₂ induced apoptosis. ROS levels were suppressed due to PBE. PBE expressed a cytoprotective nature. In vivo experiments involving the zebra fish model conformed its validity. The antioxidant efficacy of PBE was dose dependent. Study outcomes suggest PBE has potential as a novel and valuable marine resource to aid the functional food and cosmeceutical industries.

• Fisheries and Aquatic Sciences
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• v.23 no.3
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• pp.8.1-8.9
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• 2020

Background: The present study investigates the potent skin whitening ability of ethanol extract from the brown alga, Padina boryana (PBE) which was collected in the shores of Fulhadhoo Island, the Maldives, and its specific pathways of action. The effect of PBE which contains a rich amount of polyphenols was evaluated using B16F10 murine melanoma cells and provides insight to the underlying mechanisms with reference to the inhibition of melanin formation. Methods: Melanin synthesis and cellular tyrosinase inhibition were assessed in the α-MSH-stimulated melanocytes. Melanogenic pathway-related protein expressions were investigated via Western blotting. ERK 42/44 was particularly examined considering its involvement in the melanogenic pathway. Further, RT-qPCR techniques were involved in gene expression analysis. Results: PBE dose-dependently inhibited the cellular melanin synthesis and tyrosinase levels. Western blotting revealed the potential of PBE to downregulate microphthalmia-associated transcription factor (MITF), tyrosinase, and tyrosinase-related protein-1 and protein-2 (TRP-1 and TRP-2). Moreover, results explained the phosphorylation of ERK was sustained via PBE and hence declined the ultimate melanin synthesis. Gene expression analysis reinforced the results obtained. Conclusions: The study provides substantial evidence to express the potential of PBE to inhibit B16F10 melanoma cell melanin synthesis. Concisely, results suggest the ability of PBE to be involved in medicinal and cosmeceutical applications.

• ALGAE
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• v.20 no.2
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• pp.99-112
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• 2005

This monographic study presents morphological descriptions of eight species of Padina collected from the Visayas and Mindanao regions of southern Philippines, including distributions of each species and a taxonomic key for all the species examined. Of these species, three are new records for the Philippines, namely: P. fernandeziana Skottsberg and Levring, P. jonesii Tsuda and P. moffittiana Abbott and Huisman. One species, P. antillarum (Kützing) Piccone, represents a new nomenclatural record, which is applied to a Philippine species for the first time. Four species previously reported in the Philippines are reconfirmed and described P. australis Hauck, P. minor Yamada, P. boryana Thivy and P. sanctae-crucis Borgesen. All eight species studied have distromatic thalli, except for P. antillarum which is tetrastromatic. Three of these have indusiate sporangia, namely: P. sanctae-crucis, P. moffittianaand P. fernandeziana.