• 제목/요약/키워드: PTS2

검색결과 165건 처리시간 0.02초

메르스 감염 유행 후 상급종합병원 간호사의 외상 후 스트레스 영향요인 (Factors Affecting Post-Traumatic Stress of General Hospital Nurses after the Epidemic of Middle East Respiratory Syndrome Infection)

  • 김현진;박호란
    • 임상간호연구
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    • 제23권2호
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    • pp.179-188
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    • 2017
  • Purpose: This study examined post-traumatic stress (PTS) and the factors affecting it among general hospital nurses after the MERS(Middle East Respiratory Syndrome) epidemic. Methods: Data were collected from 170 nurses who worked at general hospitals since the first reported MERS outbreak. The IES-R-K assessed PTS. Data were analyzed using SPSS. Results: The mean PTS level was 7.80 points (range: 0~88); 7.1% of the participants were at a high risk. Nurses who had been in contact with patients suspected or diagnosed with MERS had high post-traumatic levels; those who had been quarantined during the MERS outbreak had relatively higher PTS levels. Shift-work nurses had higher PTS levels than those with fixed working hours. Above charge' nurses stress levels were higher than staff nurses' stress levels. The results showed that factors including contact with an MERS-suspected or diagnosed patient, position at work, and working status of MERS-affected nurses explained 16% of the PTS. Among the main variables, nurses' above charge position was the greatest factor affecting PTS. Discussion: It is necessary to develop intervention studies and programs considering these variables. Furthermore, development and implementation of differentiated programs should be done considering the position of above charge nurses.

Opposing Effects of ERK and p38 MAP Kinases on HeLa Cell Apoptosis Induced by Dipyrithione

  • Fan, Yumei;Chen, Hui;Qiao, Bo;Luo, Lan;Ma, Hsiaoyen;Li, Heng;Jiang, Jihong;Niu, Dezhong;Yin, Zhimin
    • Molecules and Cells
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    • 제23권1호
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    • pp.30-38
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    • 2007
  • Dipyrithione (2, 2'-dithiobispyridine-1, 1'-dioxide, PTS2), a pyrithione derivate, is highly bactericidal and fungicidal. In this study we examined its apoptotic effect on HeLa cells. PTS2 induced HeLa cell death in a dose and time dependent manner. ERK1/2 and p38 were markedly activated, but little JNK1/2 activation was detected. Suppression of p38 activation by SB203580 reduced the extent of apoptosis of the HeLa cells and also prevented induction of p21, release of cytochrome c, and cleavage of caspase-3 and PARP. Inhibition of ERK1/2 with PD98059 increased apoptosis, indicating that ERK1/2 activation has an anti-apoptotic effect on PTS2-induced HeLa cell apoptosis. PTS2 also inhibited murine sarcoma 180 and hepatoma 22 tumor growth in an animal tumor model. Our findings indicate that PTS2 possesses anti-tumor activity, that caspase-3 and poly (ADP-ribose) polymerase (PARP) are involved in PTS2-induced HeLa cell apoptosis and that ERK1/2 and p38 have opposing effects on this apoptosis.

Study on mechanical properties of phosphate tailings modified clay as subgrade filler

  • Xiaoqing Zhao;Tianfeng Yang;Zhongling Zong;Teng Liang;Zeyu Shen;Jiawei Li;Gui Zhao
    • Geomechanics and Engineering
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    • 제36권6호
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    • pp.619-629
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    • 2024
  • To improve the utilization rate of phosphate tailings (PTs) and widen the sources of subgrade filler, the PTs is employed to modify clay, forming a PTs modified clay, applied in the subgrade. Accordingly, the environmental friendliness of PTs was investigated. Subsequently, an optimal proportion was determined through compaction and California Bearing Ratio (CBR) experiments. Afterward, the stability of mixture with the optimal proportion was further evaluated through the water stability and dry-wet stability experiments. Finally, via the gradation and microstructure experiments, the strength mechanism of PTs modified clay was analyzed. The results show that the PTs were classified in the non-hazardous solid wastes, belonging to Class A building materials. With the increase of PTs content and the decrease of clay content, the optimum water content and the swelling degree gradually decrease, while the maximum dry density and CBR first increase and then decrease, reaching their peak value at 50% PTs content, which is the optimal proportion. The resilient modulus of PTs modified clay at the optimal proportion reaches 110.2 MPa. The water stability coefficient becomes stable after soaking for 4 days, while the dry-wet stability coefficient decreases with the increase of cycles and tends to be stable after 8 cycles. Under the long-term action, the dry-wet change has a greater adverse impact than continuous soaking. The analysis demonstrates that the better strength mainly comes from the skeleton role of PTs and the cementation of clay. The systematic laboratory test results and economic analysis collectively provide data evidence for the advantages of PTs modified clay as a subgrade filler.

물리치료사의 작업관련 근골격계 통증과 부담작업 유해요인 평가: 성인 신경계 손상 치료를 중심으로 (Work-Related Musculoskeletal Pain and Workload Evaluation of Physical Therapists: Focused on Neurological Injury Treatment of Adults)

  • 이중호;최영철;김진상
    • 한국전문물리치료학회지
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    • 제19권2호
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    • pp.69-79
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    • 2012
  • Importance of the work-related musculoskeletal disorders (WMSDs) has been increasing in the hospital industry such as health care industry and financial industry. This study investigated in order to identify the factors like general, occupational and ergonomically characteristics of the subjects related to musculoskeletal disorders (MSDs) of physical therapists (PTs). Ergonomic tools of rapid upper limb assessment (RULA) were used for evaluation workload of the tasks. Prevalence of MSDs were 13 PTs (26.0%) for neck, 31 PTs (62.0%) for shoulder, 9 PTs (18.0%) for arm/elbow, 27 PTs (54.0%) for hand/wrist, 28 PTs (56.0%) for back, 14 PTs (28.0%) for leg/foot. The analysis of the rate of the pain intensity showed that 53.5% subjects experience moderate pain and 14.0% subjects experience severe pain. Factors which were general characteristics, for example, height, ergonomically characteristics such as 'Posture Score A' were related musculoskeletal subjective symptoms in logistic analysis (p<.05). Among physical therapists, action level of RULA were action level 2 (6.0%), action level 3 (52.0%), action level 4 (42.0%). Physical therapists were estimated one of the highest risk factor in this study. This study suggested that the need of preventive education and program for PTs (physical therapists). Comprehensive and systematic management plans should be established to include both ergonomic and sociopsychological aspects.

OFDM 시스템에서 PAPR기 감소와 고속처리를 위한 새로운 적응형 PTS 기법의 성능분석 (Performance Analysis of a New Adaptive PTS Scheme for Reducing the PAPR and High Speed Processing in OFDM Systems)

  • 채주호;임연주;박상규
    • 한국통신학회논문지
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    • 제28권9A호
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    • pp.710-716
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    • 2003
  • OFDM(Orthogonal Frequency Division Multiplexing)은 주파수 이용효율을 높이고 고속의 데이터 전송이 가능하며 주파수 선택적 페이딩에 강한 전송 방식이지만, 다수 부반송파(sub-carrier)들의 중첩현상으로 인해 전송 신호의 PAPR(Peak to Average Power Ratio)이 크다는 문제점이 있다. 본 논문에서는 PAPR의 감소와 PAPR의 연산량 감소를 위해, PTS 기법에 clipping 개념을 적용하여 두개의 임계 레벨을 갖는 적응형 PTS(Partial Transmit Sequence) 기법을 제안한다. 모의실험을 통해, 제안한 기법이 만족할 만한 BER(Bit Error Rate) 성능을 유지하면서 clipping delta 값(Δ)을 1dB, 2dB 그리고 3dB로 증가 할수록 clipping 개념이 없는 기존의 적응형 PTS 기법보다 PAPR의 연산량을 크게 줄임으로써 시스템의 데이터 처리 속도면에서 우수한 성능을 가짐을 보인다.

OFDM 통신 시스템에서 PAPR을 줄이기 위한 적은 계산 복잡도를 갖는 PTS 방법 (A New PTS OFDM Scheme with Low Complexity for PAPR Reduction)

  • 임대운;허석중;노종선;정하봉
    • 한국통신학회논문지
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    • 제31권9C호
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    • pp.914-920
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    • 2006
  • 본 논문은 직교 주파수 분할 다중화(OFDM) 통신 시스템에서 최대 전력 대 평균 전력의 비 (PAPR)를 감소하기 위해서 사용되는 새로운 부분 전송 시퀀스(PTS) 기법을 제안한다. 제안하는 방법에서는 역 푸리에 변환(IFFT)을 두 부분으로 나누어 실행한다. 첫 번째 부분에서는 IFFT를 중간까지만 수행하여 입력 심볼 시퀀스를 중간 신호 시퀀스로 변환한다. 두 번째 부분은 중간 신호 시퀀스를 여러 개의 서브 시퀀스로 분할한 후 각각에 대해서 나머지 IFFT를 완료하고 PAPR을 감소하기 위한 위상 벡터를 선택한다. 본 논문에서 제안하는 PTS 기법은 기존의 PTS 기법과 유사한 PAPR 감소 성능을 보이지만 계산 복잡도를 감소시킨다.

SLM과 PTS 방식의 혼합에 의한 OFDM 신호에서의 PAPR 새로운 감소 기법 (A New PAPR Reduction Methods in OFDM by Combining SLM and PTS)

  • 기종해;김명제;유정웅;김성수
    • 한국콘텐츠학회논문지
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    • 제6권1호
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    • pp.1-7
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    • 2006
  • 본 논문에서는 Orthogonal Frequency Division Multiplexing(OFDM) 시스템의 Peak-to-Average Power Ratio(PAPR) 성능을 향상시키기 위한 목적으로 Selective Mapping(SLM)과 Partial Transmit Sequence(PTS)기법을 결합하는 방식에 있어서, 늘어나는 계산량을 감소시키는 방법을 제안한다. PAPR의 감소효율을 높이고자 하는 많은 기법 중에 SLM과PTS기법에 관한 활발한 연구가 진행되어 왔을 뿐만 아니라, SLM과PTS을 결합한 기법에 관한 많은 연구가 진행되어 왔다. 결합기법에 있어서는, 복잡성이 크게 증가하는 문제가 존재하는데, 이러한 계산량의 복잡성을 줄이는 방법으로, 본 논문에서는 N-point IFFT 알고리즘을 도입한 SLM과 PTS 기법들로 결합된 새로운 시스템을 제안하였다. 이 방법은 SLM과 PTS와의 단순 결합에 비하여 시스템의 계산량의 복잡성을 감소시키는 결과를 가져다준다. 제안된 기법에서의 계산량의 감소는 N-Point IFFT의 과정에서 생성되는 n개의 단계 중의 최적의 결과를 내는 단계에서 위상 시퀀스와 부블럭 인덱스를 곱함으로써 계산의 복잡성을 낮추어 주는 과정을 통하여 이룬다. 제안된 알고리즘의 성능의 우수성은 시뮬레이션을 통하여 실험적인 부분을 나타냈으며, 또한 해석적인 방법을 통하여 계산량이 감소함을 보였다.

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산촉매에 의한 대두유의 전이에스테르화 반응 특성 (Characteristics of Transesterification Reaction of Soy Bean Oil by Acid Catalysts)

  • 신용섭
    • 한국환경과학회지
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    • 제18권2호
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    • pp.231-238
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    • 2009
  • Characteristics of the transesterification reaction between triglycerides in soy bean oil and methanol were investigated in the presence of acid catalysts. such as sulfuric acid and PTS (p-toluene sulfonic acid). Concentrations of diglyceride and monoglyceride which were intermediates in the reaction mixtures, were far below 10% of triglyceride under any reaction conditions. Thus, conversion of the reaction could be determined from the concentration of triglyceride. Dried PTS had more superior catalytic power than sulfuric acid for transesterification reaction between soy bean oil and methanol. When transesterification reaction of soy bean oil was catalyzed by 1 wt% of PTS at methanol stoichiometric mole ratio of 2 and $65^{\circ}C$, final conversion reached 95% within 48 hours. If FAME (fatty acid methyl ester) was added into reaction mixture of soy bean oil, methanol and PTS catalyst, it converted reaction mixture into homogeneous phase, and substantially increased reaction rate. When reaction mixture was freely boiling which had equal volumetric amount of FAME to soy bean oil, methanol stoichiometric mole ratio of 2 and 1 wt% of PTS, final conversion achieved value of 94% and temperature approached to $110^{\circ}C$ within 2 hours.

Cloning, Nucleotide Sequencing, and Characterization of the ptsG Gene Encoding Glucose-Specific Enzyme II of the Phosphotransferase System from Brevibacterium lactofermentum

  • Yoon, Ki-Hong;Lee, Kyu-Nam;Lee, Jung-Kee;Park, Se-Cheol
    • Journal of Microbiology and Biotechnology
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    • 제9권5호
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    • pp.582-588
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    • 1999
  • A Brevibacterium lactofermentum gene coding for a glucose-specific permease of the phosphoenolpyruvate-dependent phosphotransferase system (PTS) was cloned, by complementing an Escherichia coli mutation affecting a ptsG gene with the B. lactofermentum genomic library, and completely sequenced. The gene was identified as a ptsG, which enables an E. coli transformant to transport non-metabolizable glucose analogue 2-deoxyglucose (2DG). The ptsG gene of B. lactofermentum consists of an open reading frame of 2,025 nucleotides encoding a polypeptide of 674 amino acid residues and a TAA stop codon. The 3' flanking region contains two stem-loop structures which may be involved in transcriptional termination. The deduced amino acid sequence of the B. lactofermentum enzyme $II^{GIe}$ specific to glucose ($EII^{GIe}$) has a high homology with the Corynebacterium glutamicum enzyme $II^{Man}$ specific to glucose and mannose ($EII^{Man}$), and the Brevibacterium ammoniagenes enzyme $II^{GIc}$ specific to glucose ($EII^{GIc}$). The 171-amino-acid C-terminal sequence of the $EII^{Glc}$ is also similar to the Escherichia coli enzyme $IIA^{GIc}$ specific to glucose ($IIA^{GIc}$). It is interesting that the arrangement of the structural domains, IIBCA, of the B. lactofermentum $EII^{GIc}$ protein is identical to that of EIIs specific to sucrose or $\beta$-glucoside. Several in vivo complementation studies indicated that the B. lactofermentum $EII^{Glc}$ protein could replace both $EII^{ Glc}$ and $EIIA^{Glc}$ in an E. coli ptsG mutant or crr mutant, respectively.

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지방대학 캠퍼스의 Barrier Free Design을 위한 설계VE 품질모델 및 가중치 제안 (A Proposal of the Quality Models and Additive Value Degrees for the Barrier Free Design in the Rural Campus Design Value Engineering)

  • 민경석
    • 한국농촌건축학회논문집
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    • 제8권1호
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    • pp.9-16
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    • 2006
  • In campus project, "Barrier Free Design" is the essential part for the handicapped. It is necessary to make a quality model that choose effective design value engineering objects. So more effective models, this study examine requests of the university students. Checked items are classified into four groups that movement, guidable, safety and territoria parts, and each groups are also divided into detailed items for basic decisional elements. When basis points sets 10, it can be divided that movement parts 2.93pts, guidable parts 2.31pts, safety parts 2.41pts and territoria parts 2.35pts. in this results, we can make additive value and quality model for barrier free design in campus design value engineering.

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