• Environmental Engineering Research
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• v.24 no.1
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• pp.91-98
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• 2019

This study was to objectify differences in the results of odor testing according to the characteristics of panel members that participate in air dilution olfactory method (ADOM) testing. When differences in the results of olfactory testing were reviewed in relation to characteristics of the panelists, the result of entire panels for the site boundary Proficiency Testing Materials (PTMs) showed no difference according to panelist sex, age, smoking status, and past participation in ADOM tests. As for the outlet PTMs, distinct differences appeared in relation to the smoking status and age of panelists. The frequency distribution for all the panelists (Dev($D/T_{total}$)) showed a form similar to a normal distribution, so it is thought to be more appropriate for the review of effect of panelist characteristics on the result of air dilution olfactory tests. In addition, the ADOM testing method implemented as the standard method for odor compounds in Korea (Dev($D/T_3$)) will have to be implemented along with a concurrent assessment, for the purpose of identifying the effect of panelist characteristics on administrative dispositions against malodors.

• Journal of Soil and Groundwater Environment
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• v.19 no.6
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• pp.49-58
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• 2014

This study was implemented as a part of the experiment to develop two kinds of soil-based Benzo[a]pyrene (BaP) proficiency testing materials (PTMs) for soil analysis. A test was carried out for the check of solubility of the reference material (high purity reagent) using several solvents. Another test was also conducted for the evaluation of homogeneity and stability of two kinds of candidate soil reference materials. The test analysis of BaP in terms of the candidate materials was conducted according to the Standard Soil Analytical Methods by Ministry of Environment. Dissolution of the reference material was shown to vary depending on solvent type and was higher in the order of Dichloromethane > Acetone > Acetone/MeOH (9 : 1) > N-hexane. In addition, the slope on calibration curve for BaP standard solutions was largest on BaP standard solutions prepared with dichloromethane of the tested solvents. Such tendency appeared egually in the commercial BaP standard solution. Therefore, it is thought to be reasonable to use dichloromethane as the solvent in case of the standard stock solution that is used for the measurement of BaP concentration in soil. ISO 13528 and IUPAC protocol were used for verification of homogeneity on the two kinds of soil candidate materials, Both candidate materials were sufficiently homogeneous. Stability assessment of the two candidate materials was made according to ISO Guide 35 and the result showed that both batches did not have any long-term and short term stability issues that might occur during shipping. However, monitoring results of BaP concentration in soil showed that BaP concentration of the two batches measured at 15 days after the sample preparation was reduced by about 24~37% compared with that of the samples measured on 0 day of the sample preparation. Identification was done with several treatments such as irradiation and sterilization etc. The major cause was shown to be irradiation to the samples.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2010.10a
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• pp.209-211
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• 2010

본 연구는 싱가폴 VTS의 현장을 직접 방문하여 파악한 시설현황과 제도를 위주로 기술하였다. 관제사의 선발 시스템 및 교육 훈련 제도가 어떻게 운용되고 있는지에 대해서도 알아보았다. 또한 현재 싱가폴 VTS에서 추구하고 있는 차세대 VTS에 대한 방향에 초점을 맞추어 우리가 벤치마킹할 요소들에 대해서 집중적으로 검토해보고 우리나라 VTS의 발전방향을 모색하여 보았다.

• Proceedings of the Korean Fiber Society Conference
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• 1998.04a
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• pp.91-96
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• 1998

본 연구에서는 환경분해성 aliphatic polyester인 Poly(tetra- methylene succinate) (이하 PTMS)의 형태학적 고찰을 통한 분해성과 구조와의 관계를 고찰하였다. 과거, 분해성 고분자는 의료용으로서 학문적인 관심의 대상이었으나, 고분자에 의한 환경 오염문제가 대두됨에 따라 산업용 고분자의 분해성에 관한 연구가 많이 진행되었다. 고분자의 분해성은 분해환경 뿐만 아니라, 고분자 사슬의 화학구조, morphology, 미결정의 크기, 분자량, 분자량 분포 등에 의해 영향을 받는 것으로 보고되었다.(중략)

• Proceedings of the Korean Fiber Society Conference
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• 2003.10b
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• pp.209-210
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• 2003

The durability and anti-microbial stability of plastics, which have been thought to be favorable characteristics, cause ecoloical problems due to non-degradation after disposal. For a possible solution of these ecological and environmental problems, the biodegradable polymers. especially aliphatic polyesters, have been widely investigated. Poly(tetramethylene succinate)(PTMS) is one of the most promising biodegradable polyesters. (omitted)

• The Korean Journal of Mycology
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• v.38 no.2
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• pp.89-94
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• 2010

Plant pathogenic fungi are the most diverse and drastic causal agents of crop diseases threatening stable food production all over the world. Plant have evolved efficient innate immune system to scout and counterattack fungal invasion and pathogenic fungi also developed virulence system to nullify plant resistance machinery or signaling pathways and to propagate and dominate within their niche. A growing body of evidences suggests that post translational modifications (PTMs) and selective/nonselective degradations of proteins involved in virulence expression of plant pathogenic fungi and plant defense machinery should play pivotal roles during the compatible and incompatible interactions. This review elucidates recent investigations about the effects of PTMs and protein degradations on host defense and fungal pathogens' invasions.

• Analytical Science and Technology
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• v.26 no.3
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• pp.165-173
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• 2013

To establishment of PT Program for Indoor air quality field that manufacture of confidential development PTMs (proficiency testing materials) and examined of proficiency testing evaluation included sampling process whether or not that is valid. Confirmation of homogeneity and stability of PTMs prepared. PTMs were confirmed to be homogeneous enough to be used as proficiency testing materials since withinbottle homogeneities of the RMs were lower than 0.3 times of targeted standard deviation of proficiency testing. The result of this study showed that the Robust RSD of proficiency testing for VOCs (volatile organic compounds) appeared 23~43% in concentration of 50~320 ${\mu}g/m^3$ for Method A(Distribution by adsorption in Tenax-tube of VOCs), but less 13~42% in concentration of 200~1200 ${\mu}g/m^3$, 16~31% in concentration of 100~450 ${\mu}g/m^3$ for Method B (distribution by VOCs of gas phase in 10L Tedalr bag), C (directly sampling of cylinder with high pressure) respectively. The result of this study showed that method C with sampling is most adequate to the proficiency testing for VOCs in indoor air.

• Mass Spectrometry Letters
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• v.8 no.4
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• pp.69-78
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• 2017

Glycosylation, which is one of the most common post-translation modification (PTMs) of proteins, plays a variety of crucial roles in many cellular events and biotherapeutics. Recent advances have led to the development of various analytical methods employing a mass spectrometry for glycomic and glycoproteomic study. However, site-specific glycosylation analysis is still a relatively new area with high potential for technologies and method development. This review will cover current MS-based workflows and technologies for site-specific mapping of glycosylation ranging from glycopeptide preparation to MS analysis. Bioinformatic tools for comprehensive analysis of glycoprotein with high-throughput manner will be also included.

• BMB Reports
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• v.51 no.6
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• pp.261-262
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• 2018

Aurora B is an important kinase involved in dynamic cellular events in mitosis. Aurora B activity is controlled by several post-translational modifications (PTMs). Among them, E3 ubiquitin ligase-mediated ubiquitination plays crucial roles in controlling the relocation and degradation of Aurora B. Aurora B, ubiquitinated by different E3 ligases, moves to the exact site for its mitotic function during metaphase-anaphase transition and is then degraded for cell cycle progression at the end of mitosis. However, how the stability of Aurora B is maintained until its degradation has been poorly understood. Recently, we have found that USP35 acts as a deubiquitinating enzyme (DUB) for Aurora B and affects its stability during cell division, thus being involved in the regulation of mitosis. In this review, we discuss the USP35-mediated deubiquitination of Aurora B and the regulation of mitotic progression by USP35.

• Biomolecules & Therapeutics
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• v.22 no.4
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• pp.308-313
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• 2014

Activator protein-1 (AP-1) is an inducible transcription factor that contributes to the generation of chronic inflammation in response to oxidative and electrophilic stress. Previous studies have demonstrated that the PI3K/Akt1 pathway plays an important role in the transcriptional regulation of AP-1 expression. Although the histone post-translational modifications (PTMs) are assumed to affect the AP-1 transcriptional regulation by the PI3K/Akt pathway, the detailed mechanisms are completely unknown. In the present study, we show that heterochromatin 1 gamma ($HP1{\gamma}$) plays a negative role in TPA-induced c-Jun and c-Fos expression. We show that TPA-induced Akt1 directly phosphorylates $HP1{\gamma}$, abrogates its suppressive function and increases the interaction between histone H3 and 14-3-$3{\varepsilon}$. Collectively, these our data illustrate that the activation of PI3K/Akt pathway may play a permissive role in the recruitment of histone readers or other coactivators on the chromatin, thereby affecting the degree of AP-1 transcription.