• Title/Summary/Keyword: PTF

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Proteomic analysis of porcine pancreas development

  • Choi, Jong-Soon;Cho, Young-Keun;Yoon, Sung-Ho;Kwon, Sang-Oh;Koo, Deog-Bon;Yu, Kweon
    • BMB Reports
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    • v.42 no.10
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    • pp.661-666
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    • 2009
  • Porcine pancreas development is not well studied at the molecular level despite being a therapeutic resource for diabetic patients. In this study, we investigated expression of lineage markers and performed proteomic analysis. Expression of the early lineage markers Pdx1 and Ptf1a was developmentally conserved between mice and pigs, whereas expression of the islet differentiation marker Pax4 was delayed in porcine compared with murine pancreas development. Proteomic analysis found that expression levels of chymotrypsinogen were down-regulated during porcine pancreas development while those of digestive enzymes like lipases, elastase and serine protease were up-regulated. In addition, specific isoforms of protein folding assistants such as protein disulfide isomerase and prefoldin were expressed at specific stages during the maturation of digestive enzymes. Taken together, these results show that development of the porcine pancreas is regulated by a concerted interplay of pancreas lineage marker proteins and other specified proteins, resulting in a functional endocrine and exocrine organ.

Post-outburst observation of HBC722 in Pelican nebula

  • Yang, Yuna;Park, Won-Kee;Sung, Hyunil;Lee, Sanggak;Yoon, Tae-Seog;Lee, Jeongeun;Kang, Wonseok;Park, Keunhong;Cho, Dong-Hwan
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.59.1-59.1
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    • 2013
  • HBC722 (also known as LkHa 188-G4 and PTF 10qpf; A. Miller et al., 2011) is one of the FU Orionis-like young stellar objects which outbursted in August 2010 (Semkov et al., 2010). We have been monitoring the post-outburst phase of this object since November 2010 with Korean Astronomy and Space Science Institute Near Infrared Camera System (KASINICS), at Bohyunsan Optical Astronomy Observatory (BOAO). Four filters, J, H, Ks, and H2 band, were used for this observation. We did aperture photometry to find photometric variation. The light curve shows a long period brightness change. After decrease of the brightness, which was reported at the KAS 2011 fall meeting, HBC722 brightens up slowly now. However we cannot confirm any short period variations, previously reported by Green et al (2013), due to large scatters in the obtained light curve.

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The Color Variability Monitoring of HBC722

  • Baek, Giseon;Pak, Soojong;Green, Joel D.;Kang, Wonseok;Jeon, Yiseul;Choi, Changsu;Lee, Jeong-Eun;Im, Myungshin
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.103.1-103.1
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    • 2012
  • We present the results of SDSS r, i and z band photometry for HBC722 (also known as $LkH{\alpha}$ 188 G4, PTF10qpf and V2493 Cyg), with Camera for Quasars in Early uNiverse (CQUEAN) attached to 2.1m Otto Struve telescope at McDonald Observatory, USA. HBC722 is a newly erupted FU Orionis type object, which produced optical outburst (${\Delta}V$=4.7 mag) over a year that peaked in 2010 September. We carried out the monitoring observations during 48 nights from 2011 April to 2012 June to check the short-term and the long-term variabilities for chasing the Keplerian rotation of the system. Comparing the photometric results of r, i and z band, we describe the color variability which is related to the physical properties of the system like circumstellar disk and accretion process.

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A Probabilistic Tensor Factorization approach for Missing Data Inference in Mobile Crowd-Sensing

  • Akter, Shathee;Yoon, Seokhoon
    • International Journal of Internet, Broadcasting and Communication
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    • v.13 no.3
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    • pp.63-72
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    • 2021
  • Mobile crowd-sensing (MCS) is a promising sensing paradigm that leverages mobile users with smart devices to perform large-scale sensing tasks in order to provide services to specific applications in various domains. However, MCS sensing tasks may not always be successfully completed or timely completed for various reasons, such as accidentally leaving the tasks incomplete by the users, asynchronous transmission, or connection errors. This results in missing sensing data at specific locations and times, which can degrade the performance of the applications and lead to serious casualties. Therefore, in this paper, we propose a missing data inference approach, called missing data approximation with probabilistic tensor factorization (MDI-PTF), to approximate the missing values as closely as possible to the actual values while taking asynchronous data transmission time and different sensing locations of the mobile users into account. The proposed method first normalizes the data to limit the range of the possible values. Next, a probabilistic model of tensor factorization is formulated, and finally, the data are approximated using the gradient descent method. The performance of the proposed algorithm is verified by conducting simulations under various situations using different datasets.

혈액형지배 유전자에 의한 칡소의 유전적 특성

  • 조창연;연성흠;손동수;이호준;윤종택
    • Proceedings of the KSAR Conference
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    • 2001.03a
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    • pp.50-50
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    • 2001
  • 혈액형을 지배하는 유전자는 진화에 대하여 중립적인 작용을 하고 있어서 집단의 유전적 구조의 특성 파악, 계통분류학 등에 많이 응용되고 있다. 본 연구는 칡소에 대한 유전학적 특성을 구명하고자 혈액형 분석기술을 응용하여 실시하였다. 공시동물은 (주)한경게놈텍 목장에서 사육중인 외모적으로 칡소의 특징을 보이는 25두를 이용하였다. 혈액은 경정맥에서 헤파린 처리된 진공 채혈관에 무균적으로 채취하여 혈장, 백혈구 및 적혈구로 원심분리한 후 냉동 혹은 냉장 보관하여 각 실험에 이용하였다. 적혈구 항원형의 검출은 2% 적혈구 부유액과 축산기술연구소에서 생산된 항혈청 11종을 이용하여 용혈반응으로 실시하였고, 혈액단백·효소를 지배하고 있는 6개의 유전자 좌위에 대하여 전분 혹은 포리아크릴 아미드겔 전기영동으로 다형 검출을 실시하였다. 용혈반응으로 검출한 적혈구 항원형의 반응양상은 검사한 11종의 항체에 대하여 6종은 50%이상의 개체에서 양성반응을 보였다. 이와 같은 결과는 일반 한우에서 보이는 양성반응율보다는 높은 것으로 판단되어진다. 전기영동법으로 분석한 6개의 혈액단백·효소 지배 유전자 좌위 중 ALB좌위을 제외한 5개 유전자 좌위에서 다형이 관찰되었다. HB, AMY-1, GC 및 PTF-2 유전자 좌위는 2개의 대립유전자가 관찰되었고, TF 유전자 좌위는 4개의 대립유전자가 관찰되었다. 표 1에서 같이 칡소에서 관찰된 각 유전자 좌위의 대립유전자 빈도의 구성은 일반적인 한우와는 상이한 결과를 보였으나 평균 이형접합도는 칡소가 0.438, 일반한우가 0.442로 계산되어 유전적 변이성은 유사한 것으로 추정되었다. 이상의 결과로 본 연구에서 분석한 칡소는 다른 한우집단과는 상이한 유전적 구조를 가지고 있으나, 유전적 다형성은 비교적 높은 것으로 시사되었다. 보다 정확하고 많은 량의 유전정보 수집을 위하여 Microsatellite DNA 및 모색 관련 유전자를 분석할 필요성이 있을 것으로 사료된다.(Table Omitted)

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Post-outburst observation of HBC722 in Pelican nebula

  • Yang, Yun-A;Sung, Hyun-Il;Lee, Sang-Gak;Jeon, Young-Beom;Lee, Jung-Eun;Sung, Hwan-Kyung;Kang, Won-Seok;Park, Keun-Hong
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.148.1-148.1
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    • 2011
  • We report the result of post-outburst observation of HBC722, the new FU Orionis-like young stellar object (also known as LkHa 188-G4 and PTF 10qpf; A. Miller et al., 2011). We have been monitoring this object since Nov. 2010 with KASINICS (Korean Astronomy and Space Institute Near Infrared Camera System) at Bohyun Optical Astronomy Observatory (BOAO). The observations were performed two times; the first observation was conducted in Nov. 19, 24, and 25, 2010. And the second one was done in March 22 and 25, 2011. We used three filters: J, H, and Ks band. We did aperture photometry with IRAF packages and standardized the photometric result (instrumental magnitude) with 2MASS data that were used as standard stars. As a result, we have found that the brightness of the target decreased in all bands and its colors reddened: the magnitudes and colors of the target are J=10.37, H= 9.49, Ks=8.59, J-H=0.88, and J-Ks=1.36 on Nov. 19, 2010. And those are J=10.81, H=9.81, Ks=9.28, J-H=1.00, and J-Ks=1.53 on March 25, 2011. The previous study showed the similar decrease of brightness in J and H band except for Ks band., They were J= 10.03, H= 9.14, and Ks= 8.65 on Sept. 2010 and those were J= 10.02, H=9.24, and Ks= 8.59 on Nov. 2010. Consequently, we can conclude that HBC722 is fading out continuously from last November to this March.

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Effects of PTFE Contents on Characteristics of Cathode for Zn Air Batteries (PTFE함량에 따른 아연공기전지의 Cathode 특성연구)

  • Kim, Jee-Hoon;Eom, Seung-Wook;Moon, Seong-In;Yun, Mun-Soo;Kim, Ju-Yong;Yug, Gyeong-Chang;Park, Jeong-Hoo
    • Journal of the Korean Electrochemical Society
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    • v.6 no.3
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    • pp.203-207
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    • 2003
  • Zinc Air batteries obtain their energy density by utilizing ambient oxygen as the cathode materials. And specific capacity of zinc powder is as high as 820 mAh/g. When Zinc Air battery discharged at low current, then discharge voltage profile has very flat pattern until reach to end of voltage. But, when Zinc Air battery discharged at high current, then discharge voltage and energy becomes very low. So we focused on resistance and porosity of cathode with contents of PTFE. Wf studied on the effects of PTFE on performance of Zinc Air batteries. So we have got optimum contents of PTFE binder.

Design of HUST-PTF beamline control system for fast energy changing

  • Li, Peilun;Li, Dong;Qin, Bin;Zhou, Chong;Han, Wenjie;Liao, Yicheng;Chen, Aote
    • Nuclear Engineering and Technology
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    • v.54 no.8
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    • pp.2852-2858
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    • 2022
  • A proton therapy facility is under development at Huazhong University of Science and Technology (HUST). To meet the need for fast energy changes during treatments, a beamline control system (BCS) has been designed and implemented. The BCS coordinates and controls various beamline devices by adopting a distributed architecture divided into three layers: the client, server, and device layers. Among these, the design of the server layer is the key to realize fast energy changes. The server layer adopts the submodule programming paradigm and optimizes the data interface among modules, allowing the main workflow to be separated from the device workflow and data. Furthermore, this layer uses asynchronous, multithreaded, and thread-locking methods to improve the system's ability to operation efficiently and securely. Notably, to evaluate the changing energy status over time, a dynamic node update method is adopted, which can dynamically adjust the update frequency of variable nodes. This method not only meets the demand for fast updates on energy changes but also reduces the server's communication load in the steady state. This method is tested on a virtual platform, and the results are as expected.

A Study on Implementation and Performance of the Power Control High Power Amplifier for Satellite Mobile Communication System (위성통신용 전력제어 고출력증폭기의 구현 및 성능평가에 관한 연구)

  • 전중성;김동일;배정철
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.1
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    • pp.77-88
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    • 2000
  • In this paper, the 3-mode variable gain high power amplifier for a transmitter of INMARSAT-B operating at L-band(1626.5-1646.5 MHz) was developed. This SSPA can amplify 42 dBm in high power mode, 38 dBm in medium power mode and 36 dBm in low power mode for INMARSAT-B. The allowable errol sets +1 dBm as the upper limit and -2 dBm as the lower limit, respectively. To simplify the fabrication process, the whole system is designed by two parts composed of a driving amplifier and a high power amplifier. The HP's MGA-64135 and Motorola's MRF-6401 were used for driving amplifier, and the ERICSSON's PTE-10114 and PTF-10021 for the high power amplifier. The SSPA was fabricated by the RP circuits, the temperature compensation circuits and 3-mode variable gain control circuits and 20 dB parallel coupled-line directional coupler in aluminum housing. In addition, the gain control method was proposed by digital attenuator for 3-mode amplifier. Then il has been experimentally verified that the gain is controlled for single tone signal as well as two tone signals. In this case, the SSPA detects the output power by 20 dB parallel coupled-line directional coupler and phase non-splitter amplifier. The realized SSPA has 41.6 dB, 37.6 dB and 33.2 dB for small signal gain within 20 MHz bandwidth, and the VSWR of input and output port is less than 1.3:1. The minimum value of the 1 dB compression point gets more than 12 dBm for 3-mode variable gain high power amplifier. A typical two tone intermodulation point has 36.5 dBc maximum which is single carrier backed off 3 dB from 1 dB compression point. The maximum output power of 43 dBm was achieved at the 1636.5 MHz. These results reveal a high power of 20 Watt, which was the design target.

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Comparison of Disk Tension Infiltrometer and van Genuchten-Mualem Model on Estimation of Unsaturated Hydraulic Conductivity (장력 침투계(Disk Tension Infiltrometer)와 van Genuchten-Mualem 모형 적용에 따른 불포화수리 전도도의 비교 해석)

  • Hur, Seung-Oh;Jung, Kang-Ho;Park, Chan-Won;Ha, Sang-Keun;Kim, Geong-Gyu
    • Korean Journal of Soil Science and Fertilizer
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    • v.39 no.5
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    • pp.259-267
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    • 2006
  • Hydraulic conductivity is the rate of water flux on hydraulic gradient. The van Genuchten Mualem (VGM) model is frequently used for describing unsaturated state of soils, that is composed with the function of soil water potential and soil water content and requests various parameters. This study is to get the value of VGM parameters used Rosetta computer program based on neural network analysis method and to calculate VGM parameters. VGM parameters included Ko(effective saturated hydraulic conductivity), ${\theta}r$(residual soil water content), ${\theta}s$(saturated soil water content), L, n and m. The unsaturated hydraulic conductivity at 10 kPa was calculated by using Rosetta program. Unsaturated hydraulic conductivities of 17 soil series at 1, 3, 5, 7 kPa were also obtained by applying saturated hydraulic conductivity by disk tension infiltrometer based on Gardner and Wooding's equation. Water flow at the water potential of 3 kPa was very low except Namgye, Hagog, Baegsan, Sangju, Seogcheon, Yesan soil series. Unsaturated hydraulic conductivity at 1 kPa showed the highest value for Samgag soil series and was in order of Yesan, Hwabong, Hagog and Baegsan soil series. Those of Gacheon, Seocheon and Ugog soil series were very low. When the value by VGM was compared with the value by disc tension infiltrometer, there was a tendency with exponential function to soils without gravel but there was no tendency to soils including gravel. Conclusively, it would be limited that VGM model for unsaturated hydraulic conductivity analysis applies to Korean agricultural land including gravel and having steep slope, shallow soil depth.