• Title/Summary/Keyword: PR Effect

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Protective Effects of Extract of Puerariae radix on Hepatic injury Induced by Carbon Tetrachloride In Rat. (갈근 추출물이 사염화탄소로 유발된 흰쥐의 간 손상에 대한 보호효과)

  • Kim, Ok-Kyung
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.3
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    • pp.443-450
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    • 2017
  • This study was done to investigate the protective effects of ethanol extract puerariae radix(Pr) on carbon tetrachloride($CCl_4$) intoxicated rats. Male sprague Dawley rats(200~210g)was used. experimental groups were divided into normal group, $CCl_4$-control group, and ethanol extract $CCl_4$-treated group. $CCl_4$-treated groups were injected with $CCl_4$ 0.6mg/kg.b.w(i.p). The activities of Alanine aminotransferase(ALT), Aspartate aminotransferase(AST), Alkaline phosphatase(ALP), Glutamyltranspeptidase(${gamma}$-GT), Lactate dehydrogenase(LDH) in extract pretrated group was significantly decreased(p<0.05) compared to the $CCl_4$-control group. The contents of triglyceride, cholesterol and lipid peroxide were significantly decreased(p<0.05). whereas content of HDL-choresterol was significantly increased.(p<0.05). In addition, activities of hepatic catalase(CAT), glutathione peroxidase(GSH-Px) in the extract pretreated rats were significantly decreased(p<0.05) compared to the $CCl_4$-control group. but the content of glutathione(GSH) was significantly increased(p<0.05). These results suggest that extract of puerariae radix(Pr) has hepatoprotective effect in the $CCl_4$-intoxicated rats.

Microstructure evolution and effect on deuterium retention in oxide dispersion strengthened tungsten during He+ irradiation

  • Ding, Xiao-Yu;Xu, Qiu;Zhu, Xiao-yong;Luo, Lai-Ma;Huang, Jian-Jun;Yu, Bin;Gao, Xiang;Li, Jian-Gang;Wu, Yu-Cheng
    • Nuclear Engineering and Technology
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    • v.52 no.12
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    • pp.2860-2866
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    • 2020
  • Oxide dispersion-strengthened materials W-1wt%Pr2O3 and W-1wt%La2O3 were synthesized by wet chemical method and spark plasma sintering. The field emission scanning electron microscopy (FE-SEM) analysis, XRD and Vickers microhardness measurements were conducted to characterize the samples. The irradiations were carried out with a 5 keV helium ion beam to fluences up to 5.0 × 1021 ions/m2 under 600 ℃ using the low-energy ion irradiation system. Transmission electron microscopy (TEM) study was performed to investigate the microstructural evolution in W-1wt%Pr2O3 and W-1wt%La2O3. At 1.0 × 1020 He+/m2, the average loops size of the W-1wt%Pr2O3 was 4.3 nm, much lower than W-1wt% La2O3 of 8.5 nm. However, helium bubbles were not observed throughout in both doped W materials. The effects of pre-irradiation with 1.0 × 1021 He+/m2 on trapping of injected deuterium in doped W was studied by thermal desorption spectrometry (TDS) technique using quadrupole mass spectrometer. Compared with the samples without He+ pre-irradiation, deuterium (D) retention of doped W materials increased after He+ irradiation, whose retention was unsaturated at the damage level of 1.0 × 1022D2+/m2. The present results implied that irradiation effect of He+ ions must be taken into account to evaluate the deuterium retention in fusion material applications.

Performance Evaluation of Multi Effect Distillation for Solar Thermal Desalination (태양열 해수담수화를 위한 증발식 다중효용 담수기 성능평가)

  • Joo, Hong-Jin;Kwak, Hee-Youl
    • 한국태양에너지학회:학술대회논문집
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    • 2011.04a
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    • pp.74-79
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    • 2011
  • This study was accomplished to evaluate the performance of Multi Effect Distillation(MED) for solar thermal desalination system. It was designed Multi effect distillation with $3m^3/day$ capacity and Shell&Tube type heat exchanger. Also, The effective heat transfer of Shell&Tube heat exchanger was used Cu(90%)-Ni(10%) corrugated tube. The parameters relating to the performance of Multi Effect Distillation are known as hot water flow rate. The experimental conditions for each parameters were $18^{\circ}C$ for sea water inlet temperature, $6m^3/hour$ sea water inlet volume flow rate, $75^{\circ}C$ for hot water inlet temperature, 2.4, 3.6, and $4.8m^3/hour$ for hot water inlet volume flow rate, respectively. The results are as follows, Development for Multi effect distillation was required about 40kW heat and 35kW cooling source to produce $3m^3/day$ of fresh water. And, Performance ratio of Development Multi effect distillation was about 2.0191.

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Process Design of Carbon Dioxide Storage in the Marine Geological Structure: II. Effect of Thermodynamic Equations of State on Compression and Transport Process (이산화탄소 해양지중저장 처리를 위한 공정 설계: II. 열역학 상태방정식이 압축 및 수송 공정에 미치는 영향 평가)

  • Huh, Cheol;Kang, Seong-Gil
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.11 no.4
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    • pp.191-198
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    • 2008
  • To design a reliable $CO_2$ marine geological storage system, it is necessary to perform numerical process simulation using thermodynamic equation of state. $CO_2$ capture process from the major point sources such as power plants, transport process from the capture sites to storage sites and storage process to inject $CO_2$ into the deep marine geological structure can be simulate with numerical modeling. The purpose of this paper is to compare and analyse the relevant equations of state including ideal, BWRS, PR, PRBM and SRK equation of state. We also studied the effect of thermodynamic equation of state in designing the compression and transport process. As a results of comparison of numerical calculations, all relevant equation of state excluding ideal equation of state showed similar compression behavior in pure $CO_2$. On the other hand, calculation results of BWRS, PR and PRBM showed totally different behavior in compression and transport process of captured $CO_2$ mixture from the oxy-fuel combustion coal-fired plants. It is recommended to use PR or PRBM in designing of compression and transport process of $CO_2$ mixture containing NO, Ar and $O_2$.

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Online Dead Time Effect Compensation Algorithm of PWM Inverter for Motor Drive Using PR Controller

  • Park, Chang-Seok;Jung, Tae-Uk
    • Journal of Electrical Engineering and Technology
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    • v.12 no.3
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    • pp.1137-1145
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    • 2017
  • This paper proposes the dead time effect compensation algorithm using proportional resonant controller in pulse width modulation inverter of motor drive. To avoid a short circuit in the dc link, the dead time of the switch device is surely required. However, the dead time effect causes the phase current distortions, torque pulsations, and degradations of control performance. To solve these problems, the output current including ripple components on the synchronous reference frame and stationary reference frame are analyzed in detail. As a results, the distorted synchronous d-and q-axis currents contain the 6th, 12th, and the higher harmonic components due to the influence of dead time effect. In this paper, a new dead time effect compensation algorithm using proportional resonant controller is also proposed to reduce the output current harmonics due to the dead time and nonlinear characteristics of the switching devices. The proposed compensation algorithm does not require any additional hardware and the offline experimental measurements. The experimental results are presented to demonstrate the effectiveness of the proposed dead time effect compensation algorithm.

Anti-pruritic Effect of Ethanol Extracts from Platycodon grandiflorum and its fermented production in Scratching Behavior Mouse Models (길경(桔梗)발효 추출물의 알레르기성 소양행동 억제효과연구)

  • Ha, Mi-Ae;Kim, Jin-Woo;Lee, Shin-Woo;Chun, Hyun-Sik;Cho, Young-Son;Shin, Yong-Wook
    • The Korea Journal of Herbology
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    • v.29 no.6
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    • pp.165-173
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    • 2014
  • Objectives : Platycodon Root is frequently used in traditional medicine to treat inflammatory diseases of the throat. The purpose of this study was to characterize the effect of the EtOH extract of fermented Platycodon grandiflorum on the ameliorative effects on the Antipruritic Effect of atopic dermatitis mouse model induced by compound 48/80 and ovalbumin (OVA)-induced allergic responses in mice. Methods : In the present study, we examined the anti allergic effect of Platycodon grandiflorum (PR) and its fermented production (FPR) in several mouse model. We measured acute ear edema in a mouse model caused by TPA and consecutively histological change of Ear tissue was observed by hematoxylin and eosin (H&E) staining. and also Scratching behaviors by compound 48/80 was investigated. The levels of allergic mediators such as immunoglobulin (Ig) E, and anti-oxidant markers such as SOD and MDA in the sera of OVA induced allergic mice were measured by enzyme-linked immunosorbent assay. Results : FPR inhibited compoud 48/80-induced scratching behavior in mice, as well as acetic acid-induced writhing in mice. The anti-scratching behavioral effect of FPR was more potent than PR. FPR extract significantly decreased the serum levels of IgE and MDA compared with those of OVA control group. Conclusions : These results indicate that Anti allergic effect of Platycodon grandiflorum is enhanced by fermentation with Saccharomyces cerevisae and FPR may be useful for protection from the itching reactions, which are IgE-mediated representative skin allergic diseases.

Culture Methods for the Production of Clean Soybean Sprouts - I. Effect on Growth of Soybean Sprouts under the Temperature Control of Culture and Water Supply (청정콩나물 재배기술 - I. 재배온도 및 수온이 콩나물 생육에 미치는 영향)

  • Kim Sun-Lim;Hwang Jong-Jin;Son Young-Koo;Song Jin;Park Keum-Yong;Choi Kwang-Soo
    • 물만먹고자라요
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    • no.10
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    • pp.18-24
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    • 2000
  • Six soybean varieties including recommended variety, local and imported soybean Variety were investigated the effect on the growth of soybean sprouts under the various temperatures of culture and water supply, and to develop the culture methods for the pr

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Effects of Inflation Pressure on Tractive Performance of Bias-Ply Tires (공기압이 바이어스 플라이 타이어의 견인 성능에 미치는 영향)

  • 이동렬;김경욱;정병학
    • Journal of Biosystems Engineering
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    • v.23 no.1
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    • pp.1-12
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    • 1998
  • This study was intended to investigate experimentally the effect of inflation pressure on tractive performance of bias-ply tires for agricultural tractors. Traction tests were conducted at the three velocities of 3, 4, and 5.5km/h under few different surface conditions using a 13.6-28 6PR bias-ply tire as driving wheel of the test tractor. When the inflation pressure was reduced from 250kPa to 40kPa by a decrement of either 30 or 50kPa depending upon the test surface conditions, some of the test results showed that the tractive coefficient and efficiency were increased maximally by 40% and 17%, respectively, at 20% slippage. However, it was failed to derive any consistent rules depicting the effect of inflation pressure of bias ply tires on the tractive performance of tractors.

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A Comparative Study on the Method of Consequence Estimation for Release of Toxicant Substances (독성물질 누출의 강도 산정 방법에 관한 비교 연구)

  • 김윤화;백종배;고재욱
    • Journal of the Korean Society of Safety
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    • v.9 no.1
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    • pp.89-94
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    • 1994
  • Two methods, the numerical method of CPQRA and the manual method of IAEA, were used to estimate the effect distance from release and dispersion of toxic materials. The Gaussian plume model which has a weather stability class D with wind velocity of 5m/s was applied to calculate dispersion of toxic materials. Also, probit function were employed to evaluate the human fatality as a result of exposure to toxic gases. Furthermore, concentration of toxic materials corresponding to LC$_{50}$ for 30 min could be determined by setting Pr as 5.0 and solving the probit function. Calculations were conducted by employing chlorine and ammonia as toxic materials because they are not only most commonly used In chemical plants but also very harmful to humans. Calculated results by employing toxic materials indicated that the effect distance from the CPQRA method was between the minimum and maximum distance from the method proposed by IAEA.A.

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Fabrication of a Micro Cooler using Thermoelectric Thin Film (열전박막을 이용한 마이크로 냉각소자 제작)

  • Han, S.W.;Choi, H.J.;Kim, B.I.;Kim, B.M.;Kim, D.H.;Kim, O.J.
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.1459-1462
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    • 2007
  • In general a thermoelectric cooler (TEC) consists of a series of P type and N type thermoelectric materials sandwiched between two wafers. When a DC current passes through these materials, three different effects take place; Peltier effect, Joule heating effect and heat transfer by conduction due to temperature difference between hot and cold plates. In this study we have developed a micro TEC using $Bi_2Te_3$ (N type) and $Bi_{0.5}Sb_{1.5}Te_3$ (P type) thin films. In order to improve that performance of a micro TEC, we made 10 um height TE legs using special PR only for lift-off. We measured COP (coefficient of performance) and temperature difference between hot and cold connectors with current.

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