• Proceedings of the Korean Vacuum Society Conference
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• 2004.08a
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• pp.78-78
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• 2004

• The Korean Journal of Pharmacology
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• v.31 no.2
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• pp.251-259
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• 1995

Pharmacokinetics and pharmacodynamics of metoprolol, a selective beta-l blocker, were examined for 360 minutes after intravenous bolus administration of metoprolol to 6 dogs. Plasma concentration and excreted amount in the urine metoprolol were measured by liquid chromatography with fluorescence detection. PR interval and heart rate were measured by ECG monitoring. Blood pressure was monitored through intraarterial catheter in femoral artery and cardiac output by thermodilution method using Swan-Ganz catheter. To analyze the effect site concentration-response relationship, plasma concentration and pharmacological effects were simultaneously fitted to a two pharmacokinetic compartment linked to pharmacodynamic model with NONLIN program. Results are as follows. 1) The plasma concentration of metoprolol after intrvenous injection decreased biexponentially. The terminal half-life estimated was $1.33{\pm}0.40$ hours and the volume of distribution at steady state (Vdss) and the total body clearance were $1.04{\pm}0.4\;L/kg,\;6.55{\pm}2.21\;L/hr$, respectively. The central compartment volume of distribution and peripheral compartment volume of distribution were $0.35{\pm}0.14L/kg\;and\;0.69{\pm}0.34L/kg$. The renal clearance and intercompartment clearance were $0.53{\pm}0.25\;L/min\;and\;0.35{\pm}0.19\;L/min$. 2) Simulated biophase concentration-response curve shows hyperbolic relationship and the estimated concentration-effect relationship was best explained by Emax model when the prolongation of PR interval and the reduction of the heart rate were used as pharmacodynamic parameters. Emax and EC50 were estimated to be $26.3{\pm}4.7\;msec\;and\;88.8{\pm}82.3\;g/ml$ for PR interval, and $48.7{\pm}18.8\;beats/min\;and\;113.5{\pm}78.7\;ng/ml$ for heart rate, respectively. 3) The changes of cardiac output-effect site concentration relationship was best fitted by a linear model and the slope of the relationship was $0.005{\pm}0.003$. Diastolic blood pressure-effect site concentration relationship was also explained by the linear model and the slope of the relationship was $0.038{\pm}0.034$.

• Proceedings of the Optical Society of Korea Conference
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• 2002.07a
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• pp.44-45
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• 2002

1.3$mu extrm{m}$ 대역에서 증폭특성을 갖는 광섬유 증폭기인 Praseodymium-doped fiber amplifier(PDFA)는 Ohishi 등에 의해서 처음으로 제안되었다. 수십 nm의 이득 대역폭을 갖고, 30dB 이상의 높은 신호 이득을 갖는 PDFA는 1.3～l.6$\mu\textrm{m}$에 이르는 광대역 WDM을 위한 중요한 증폭기로 사용되고 있다. 최근에는 1.3~1.6$\mu\textrm{m}$에 이르는 광대역 WDM을 위해 광섬유 증폭기의 이득을 shift시키고, 이득 평탄화를 위한 많은 연구가 진해되어 지고 있으나, 광섬유 내에서 초고속의 광 신호를 증폭 시 발생할 수 있는 상호채널 간섭, 상호변조 왜곡, bit rate 높은 펄스열의 증폭 시 발생할 수 있는 이득소멸(gain depletion)과 이득회복(gain recovery) 등과 같은 과도응답 현상에 관한 연구는 충분히 보고되어있지 않다. (중략)

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.6
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• pp.81-86
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• 2007

Biodiesel fuel that consists of saturated and unsaturated long-chain fatty acid alkyl esters is an alternative diesel fuel produced from vegetable oils or animal fats. However, air causes autoxidation of biodiesel fuel during storage, which can reduce fuel quality by adversely affecting its properties, such as the kinematic viscosity and acid value. One approach for improving the resistance of fatty derivatives to autoxidation is to mix them with antioxidants. This study investigated the effectiveness of five such antioxidants in mixtures with biodiesel fuels produced by three biodiesel manufacturers : tert-butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), propyl gallate (PrG) and $\alpha$-tocopherol. Oxidation stability was determined using Rancimat equipment. The results show that TBHQ, BHA, and BHT were the most effective and $\alpha$-tocopherol was the least effective at increasing the oxidation stability of biodiesel. This study recommends that TBHQ and PrG be used for safeguarding biodiesel fuel from the effects of autoxidation during storage.

• Proceedings of the KIPE Conference
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• 2014.11a
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• pp.157-158
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• 2014

단상 계통연계형 인버터에서 전류센서를 통한 상전류 측정시 옵셋 오차는 전류센서와 측정 경로상에 위치한 아날로그 소자의 전압 불균형 및 비선형성으로 인하여 발생하게 된다. 또한 데드타임은 전력용 반도체 스위치를 제어하기 위한 PWM 신호 출력시 필연적으로 발생된다. 본 논문에서는 데드타임으로 인하여 왜곡된 상전류에 포함된 옵셋 오차에 의한 영향을 분석하고 동기좌표계 dq축 전류에 포함된 특정 고조파 성분을 제거하기 위하여 PR 제어기를 사용한 알고리즘이 제안되었다. 데드타임 및 옵셋 오차로 인해 발생된 전류맥동 보상을 위한 기준신호로는 동기좌표계 dq축 전류를 사용하였다. 제안된 알고리즘의 타당성을 시뮬레이션과 실험을 통하여 증명하였다.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.268-269
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• 2006

The estimation of applicability $SrTiO_3:Pr^{3+}$, Al to a class low-voltage flat-panel displays based on field emission effect, which have average value anode voltage $U_a=300V$ and current density $j=100\;mA/sm^2$ at duty 240, has given positive result. In the same time observably for the most effective sample in similar conditions of excitation high brightness - more than $500\;Kd/m^2$ and linear brightness dependences from current density and voltage allows to decrease greatly the power which consumed by the device.

• Journal of the Korean Ceramic Society
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• v.33 no.3
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• pp.313-320
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• 1996

We have fabricated an in-plane aligned a-axis oriented YBa2Cu3O7-x (a-YBCO) thin film on a LaSrGaO4(100) substrate with a PrBa2Cu3O7-x(PBCO) template layer by two step plused laser deposition using 308 nm XeCl excimer laser. A YBCO layer and PBCO layer grown at low temperatures were used as template layers. We have investigated the effect of the deposition temperature of template layers on the superconducting and struc-tural properties of in-plane aligned a-YBCO thin films. An optimal deposition temperature of the PBCO template layers was 630. In-plane aligned a-YBCO thin films showed an anisotropy ratio in resistivity of 11.5 and a zero resistance temperature of 88 K.

• Journal of computational fluids engineering
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• v.6 no.3
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• pp.1-9
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• 2001

Mixed convection in a horizontal annulus is considered, and the effect of a forced flow on the natural convective flow is investigated. The inner cylinder is hotter than the outer cylinder, and the outer cylinder is rotating with constant angular velocity with its axis at the center of the annulus. The unsteady streamfunction-vorticity equation is solved with a finite difference method. For the fluid with Pr=0.7, there appear flows with two eddies, one eddy, or no eddy according the Rayleigh and Reynolds numbers. The rotation of the outer cylinder reduces the heat transfer rate at the wall of the annulus. The oscillatory multicellular flow of a low Prandtl number fluid with Pr=0.01 can be effectively suppressed by the forced flow.

• Proceedings of the KIEE Conference
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• 2007.04a
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• pp.196-198
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• 2007

A circuit design technique to reduce the propagation time is proposed for the analog parallel processing-based Viterbi decoder. The analog Viterbi decoder implements the function of the conventional digital Viterbi decoder utilizing the analog parallel processing circuit technology. The decoder is for the PR(1.2,2.1) signal of DVD. The benefits are low power consumption and less silicon occupation. In this paper, a propagation time reduction technique is proposed by minimizing the parasitic capacitance components in the layout design of the analog Viterbi decoder. The propagation time reduction effect of the proposed technique has been shown via HSPICE simulation.

• Journal of the Korean Ceramic Society
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• v.51 no.6
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• pp.612-617
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• 2014

The microstructure, nonlinear properties, and impulse clamping characteristics of Pr/Co/Cr/Al co-doped zinc oxide ceramics were investigated with various contents of $Er_2O_3$. Increasing $Er_2O_3$ content increased the density of the sintered pellets from 5.69 to $5.83g/cm^3$, and decreased the average grain size from 10.6 to $6.5{\mu}m$. With increased $Er_2O_3$ content, the breakdown field increased from 2318 to 4205 V/cm, and the nonlinear coefficient increased from 19.4 to 40.2. The clamp characteristics were improved with the increase of the content of $Er_2O_3$. The varistors doped with 2.0 mol% exhibited the best clamp characteristics, in which the clamp voltage ratio was 1.40-1.73 at 1-50 A in an impulse current.