• Title/Summary/Keyword: POE analysis

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Designing Inhibitor against Phospholipases A2 Enzyme through Inslico-Molecular Docking Studies

  • Ganapathy, Jagadeesan;Govindhan, Suresh;Sanmargam, Aravindhan
    • Journal of Integrative Natural Science
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    • v.7 no.3
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    • pp.159-165
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    • 2014
  • Pyrazole, hydroxyimino, aldehyde and isoxazole derivatives exhibit a broad spectrum of biological activities such as antimicrobial, anti-inflammatory and antitumor activities. With growing application on their synthesis and bioactivity, chemists and biologists in recent years have considerable attention on the research of these derivatives. In the view of potential importance of these derivatives, we have crystallized few of the derivatives and its report has been published. The present study focuses on docking studies of these derivatives against Phospholipases $A_2$ enzyme. This enzymes has implicated as potential targets for anti-inflammatory drug design. co-crystal structure (PDB ID: 1POE) of $PLA_2$ deposited in Protein Data Bank has been retrieved for docking analysis. Docking studies using Schrodinger's GLIDE reveals that these derivatives shows better binding energy and score in the defined active site. These results may provide a guiding role to design a lead molecule which may reduce inflamation.

A Study on the Eco-friendly, Sustainable Underground Campus Plan - Based on the Case Study and User Satisfaction Research - (지속가능한 친환경 지하캠퍼스 계획 방향에 관한 연구 -사례분석과 이용자 만족도 조사를 중심으로-)

  • Chung, Jae-Hee;Lee, Sang-Yun
    • Journal of the Korean Institute of Educational Facilities
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    • v.17 no.6
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    • pp.13-22
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    • 2010
  • This study aims to propose design directions for the eco-friendly, sustainable underground campus in terms of integrated design. For this purpose, theoretical investigation, design methodology and quality investigation, analytical case studies on the domestic and foreign underground campus, and user survey for POE(Post Occupancy Evaluation) and analysis on the recently built domestic underground campus plans were conducted. As a conclusion, design direction and improvement areas for the synthesized sustainable underground campus plan were proposed. Underground campus plan will be a great alternative for a 21st century sustainable campus if well-developed plans with organized design guidelines are established.

Manufacturing Process of Translucent Microemulsion and Its Stability (Translucent Microemulsion의 제조 공정과 안정성)

  • Bae, Duck-Hwan;Shin, Jae-Sup
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.3
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    • pp.167-173
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    • 2000
  • The process variables for the manufacture of translucent microemulsion prepared with 2-octyl dodecanol, 12-hydroxy stearic acid cholesteryl , POE(40)HCO and 1,3-butandiol were examined initially (primary emulsion) and following aging for three months. The techniques empolyed in this study were particle size, turbidity, interfacial tension and microfluidizer. Particle size analysis and turbidity measurement to evaluate the emulsion stability were used. It was concluded that the process of the emulsification was an important indicator of the stability of the translucent microemulsion. From the particle size and and turbidity measurement of translucent microemulsion, adding the surfactant to the oil phase before the emulsification was found to be the most important factor for the stability of emulsions. We found that interfacial tension of the adding the surfactant to the oil phase is lower than that of the adding the surfactant to aqueous phase. In spite of hydrophilic surfactant, adding the surfactant to aqueous phase produced inferior emulsion to that to oil phase.

A study on the post-occupancy evaluation of remodeling apartment (리모델링 아파트의 거주 후 평가 연구)

  • Choo, Sun-Kyong;Park, Joong-Hyun;Kang, Boo-Seung
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2008.04a
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    • pp.221-224
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    • 2008
  • The purpose of this study is analyzed that the case of remodeling of apartment housing and dweller's consciousness in proposed site of remodeling. The manner of this study focused on the analysis of previous study and documentary survey to the dweller's consciousness level in entire building unit and housing unit of remodeling. The study result was showed that the dwellers who have experienced the remodeling of housing units have a higher recognition than entire building unit, and dweller favor with the variation of extending balcony in remodeling.

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A Study on the Residents′ Post Occupancy Evaluation of the Environment-Friendly Housing Certification (주거환경 우수주택 인증단지의 거주 후 평가에 관한 연구)

  • 최윤아;송병하
    • Korean Institute of Interior Design Journal
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    • v.13 no.5
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    • pp.98-105
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    • 2004
  • The importance of environment has been increased recently, and it has affected architectural area especially no less than any other area. This study performed POE on the housing sectors, which have been approved as ‘The Environment-Friendly Housing Certification (KOEAM 2000)’, to evaluate the recognition and value of the residents. The study employed survey method and the items of questionnaire are based on the detailed criteria of the ‘The Environment-Friendly Housing Certification (KOEAM 2000)’. Through the analysis of investigated substance, this study compared the differences between the quantitative satisfaction and the qualitative satisfaction of the residents, and investigated the differences between the degree of satisfaction and the degree of importance, and the preference to the evaluation criteria. As a result, it is deduced that the qualitative aspects rather than the quantitative aspects affects the satisfaction of residents more in some criteria. It is also investigated that the awareness and requirements level of residents varies according to the demographics, and the differences between the evaluation criteria of the residents and the certification system is also deduced. Through this analysis, this study tried to find the supplemental points of the certification system which pursue the sustainable development and accommodate the requirements of residents.

A Study on the Post Occupancy Evaluation of Xi'an Castle Park in China (중국 서안시 명성곽공원의 이용실태에 관한 연구)

  • Kim, Dong-Chan;Ma, Yuan
    • Journal of the Korean Institute of Landscape Architecture
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    • v.39 no.1
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    • pp.75-83
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    • 2011
  • This research aims to grasp the use status and satisfaction level based on citizen consciousness to improve future design. This study employs a combination literature review and field survey. In the literature review, the related materials were collected to obtain the most useful information for references, and the POE study of the Xi'an Ming City Wall Park was conducted. The survey instrument is a questionnaire that includes questions regarding Xi'an Ming City Wall Park. Data were analyzed using the Statistical Package for the Social Sciences(SPSS17.0 for Windows). Through the POE analysis of the usage status and variables which significantly affect the users' degree of satisfaction with the spaces and facilities were investigated and the following problems have been found.Xi'an Ming City Wall Park requires extensive modification to meet the demands of citizens. Several shortcomings are hampering the development of the park. The rest space and the nightscape seem to be the two most problematic aspects in the park. The nightscape design should be particularly emphasized in the overall park design in the future. The results also show that the major population visiting the park is the elderly, so the characteristics of this age should be taken into consideration when improvement decisions are made, and the facilities and activities suitable to elderly people should also be increased.

A Comparative Study on the Basic Values and Operating Evaluation of Innovative Schools in Korea (국내 혁신학교 기본가치와 운영 평가 비교 연구)

  • Park, heejin;Nam, mi;Kwon, dongtaik
    • Korean Journal of Comparative Education
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    • v.28 no.6
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    • pp.131-152
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    • 2018
  • In terms of the fact that Innovation School is the main agent which encourages the innovation of school culture, As it has been ten years since the Innovation School was enforced, we do need a practical, indepth study on the quality of policy management. To make this actualize, this study is for analysis and comparison of basic values and operating evaluation plans which have been managed by Metropolitan City Office of Education(MCOE) & Provincial Office of Education(POE). Each of MCOE & POE have their own vision. Those visions are such things; 'Education for All' for Gangwon, Busan, Chungbuk. 'Future School Orientation' for Gyeonggi, Gyeongnam. 'Educational Community Realization' for Gwangju, Seoul, Ulsan, Jeonbuk, Jeju. 'Normalization of Public Education' for Sejong, Incheon, Chungnam. Like such things, each office possesses different vision by their distinct characteristics and in principle, all emphasis on publicness, democracy, and creativity. Management evaluations of the Innovation School is operated by Self-assessment, Intermediate evaluation, and Extensive assessment. The process and evaluation index of Intermediate evaluation and Extensive assessment are similar. Especially, Those assessment have significance in a role of administrating its management of each school and a role of offering associated documents of educational policy with educational renovations with feedback and some good examples.

An Analysis of Features in Self Generated Analogies during Phaseal Teaching Learning Process about Mixture Using Analogy for Lower Elementary School Students (초등학교 저학년 학생들의 단계적 비유추론 학습과정을 통한 혼합물 학습 과정에서 제시된 생성적 비유의 특징 분석)

  • Jung, Jin Kyu;Kim, Youngmin
    • Journal of Korean Elementary Science Education
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    • v.34 no.4
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    • pp.419-433
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    • 2015
  • Analogical reasoning is a central component of human cognition and contributes to scientific discovery and to develop science education. In this study, we investigated the process features of lower elementary school students' analogical reasoning to explain mixture concept. The subjects are 24 lower elementary students. And the research design includes three phases instruction to investigate the features of students' self generated analogy. Phase 1 is the introduction of analogy in which student learn to use analogy. Phase 2 is a POE class about mixture conception. Piaget and Inhelder studied the conception of mixing among children in relation to cognitive development. In phase 2, we taught the student with Piaget and Inhelder's the experiment and observed the features of learning process about mixture conception. Phase 3 is students' generation of analogy (self generated analogy) for the experienced phenomena in phase 2. We analyzed the students' responses through the three phases in the view of Gentner's Structure Mapping Theory. The results showed that many lower elementary school students even before formal operation stage understood the mixture conception and made well their self generated analogy to explain the mixture conception in spite of the difficulty of making self generated analogy.

Occupants' Preferences for Housing Unit Plan by Using Computer Media and Conjoint Analysis (거주자가 선호하는 아파트 평면구성 유형 - 컴퓨터 미디어와 컨조인트 분석방법을 이용하여 -)

  • 오찬옥;김석태;최병숙
    • Korean Institute of Interior Design Journal
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    • v.13 no.2
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    • pp.109-119
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    • 2004
  • This study was intended to grasp the housing unit plan which the residents preferred. The subjects were 100 housewives who lived in 85$m^2$ sized housing units in the New Apartment Complex, Gimhae. First, four elements of unit plan were selected on the basis of the results of the POE which was carried out for the same subject the size of master bedroom and living room, the openness of dining/kitchen from living room, the openness of living room from entrance, and whether or not a bathtub or a shower booth is in bathroom. Then, eight design alternatives of unit plan made by combination of these four elements according to orthoplan were visualized by computer media. This visualized tool was used for collecting data. The results of the study were as follows: The important determinants of the residents' preferences for unit plan were the size of master bedroom and living room and the openness of living room from entrance. The residents preferred the unit plan which living room was large and the view from living room to dining/kitchen was open. Also, the important elements were different according to the characteristics of the residents. Therefore, the housing alternatives which are flexible and optional would be desirable.

Analysis and lest of On-line and off-line PD Testing for High Voltage Rotating Machines Stator Windings using Ceramic Coupler (세라믹 커플러를 이용한 고전압회전기 고정자권선의 On-line 및 off-line 부분방전 특성 시험 및 분석)

  • Oh, Bong-Keun;Kim, Hyun-Il;Kang, Seong-Hwa;Lim, Kee-Joe
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.20 no.10
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    • pp.895-900
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    • 2007
  • Partial discharge(PD) test can be performed either when the rotating machine is not operating(off-line) or during normal machine operation(on-line). This paper presents an on-line and off-line PD test on a large hydro-generator and induction motor using the same PD acquisition system(PDAS) and ceramic coupler(CC) sensor. PD signal characteristics of CC sensor proved similar with that of epoxy mica coupler(EMC) sensor as a results of PD test for simulated defect winding and frequency response test. A comparison of on-line and off-line PD test for PD characteristic parameters-phase resolved PD(PRPD), maximum PD value(Qmax) and PD occurrence energy(POE)-indicated that on-line PD test could reliably and effectively diagnose insulation conditions which were verified by off-line PD test.