• The Korean Journal of Physiology and Pharmacology
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• 제22권3호
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• pp.331-341
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• 2018

The aim of the present study was to examine the effects of preemptive analgesia on the development of trigeminal neuropathic pain. For this purpose, mechanical allodynia was evaluated in male Sprague-Dawley rats using chronic constriction injury of the infraorbital nerve (CCI-ION) and perineural application of 2% QX-314 to the infraorbital nerve. CCI-ION produced severe mechanical allodynia, which was maintained until postoperative day (POD) 30. An immediate single application of 2% QX-314 to the infraorbital nerve following CCI-ION significantly reduced neuropathic mechanical allodynia. Immediate double application of QX-314 produced a greater attenuation of mechanical allodynia than a single application of QX-314. Immediate double application of 2% QX-314 reduced the CCI-ION-induced upregulation of GFAP and p-p38 expression in the trigeminal ganglion. The upregulated p-p38 expression was co-localized with NeuN, a neuronal cell marker. We also investigated the role of voltage-gated sodium channels (Navs) in the antinociception produced by preemptive application of QX-314 through analysis of the changes in Nav expression in the trigeminal ganglion following CCI-ION. Preemptive application of QX-314 significantly reduced the upregulation of Nav1.3, 1.7, and 1.9 produced by CCI-ION. These results suggest that long-lasting blockade of the transmission of pain signaling inhibits the development of neuropathic pain through the regulation of Nav isoform expression in the trigeminal ganglion. Importantly, these results provide a potential preemptive therapeutic strategy for the treatment of neuropathic pain after nerve injury.

• 한국식품과학회지
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• 제9권1호
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• pp.61-67
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• 1977

고추씨를 분리(分離)하는 방법(方法)으로 자유낙하(自由落下), 상하진탕, 회전사(回轉篩)를 이용(利用)하는 방법(方法)과 그 기구(機構)에 관(關)하여 연구(硏究)한 결과(結果) 씨의 분리(分離)는 고추에 가(加)해 주는 충격량(衝擊量)으로 설명(說明)할 수있었으며, 이를 운동량(運動量)의 크기로 분석(分析)하였다. 씨의 분리(分離)에 기여(寄與)하는 운동량(運動量)의 영향은 속도(速度)를 얻은 방법(方法)에 따라 상이(相異)하였다. 한편 동일속도하(同一速度下)에서 운동량(運動量)의 씨분리효과(分離？果)를 산출(算出)하였으며, 자유낙하(自由落下), 상하진탕 및 회전사방법(回轉篩方法)에서 각각(各各) $2.50{\times}10^{-6}$, $2.09{\times}10^{-6}$과 $3.94{\times}10^{-8}$의 값을 보였다. 고추씨의 분리속도(分離速度)의 변화율(變化率)은 고추의 건조속도(乾燥速度)의 변화율(變化率)과 유사한 경시적(經時的) 변화양상(變化樣相)을 갖고 있었다.

• 방사선산업학회지
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• 제5권1호
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• pp.7-13
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• 2011

The present study has been performed to compare the physiological analysis of monocot model plant (rice) in response to ionizing irradiations (cosmic-ray, gamma-ray, and Ion beam). Ionizing radiations were implanted into monocot model plant (rice) seed. After irradiation, the seeds were planted in the plastic pots for a growth period of one month. Thereafter, the morphological and physiological characteristics including malondealdehyde (MDA) and chlorophyll content, activities of antioxidant enzymes in irradiation samples were investigated. We are confirmed that the activity level of MDA and chlorophyll content were not changed by ionizing irradiation samples. However, the free radical contents were increased in all irradiated plants. And the activities of SOD, POD, and APX were significantly increased by irradiation compared with non-irradiation plant.

• Plant Breeding and Biotechnology
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• 제5권3호
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• pp.237-242
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• 2017

AT-hook proteins of plant have shown to be involved in growth and development through the modification of chromatin architecture to co-regulate transcription of genes. Recently, many genes encoding AT-hook protein have been identified and their involvement in senescence delay is investigated. In this study, soybean transgenic plants overexpressing chromatin architecture-controlling ATPG7 gene was produced by Agrobacterium-mediated transformation and investigated for the positive effect on the important agronomic traits mainly focusing on yield-related components. A total of 27 transgenic soybean plants were produced from about 400 explants. $T_1$ seeds were harvested from all transgenic plants. In the analysis of genomic DNAs from soybean transformants, ATPG7 and Bar fragments were amplified as expected, 975 bp and 408 bp in size, respectively. And also exact gene expression was confirmed by reverse transcriptase-PCR (RT-PCR) from transgenic line #6, #7 and #8. In a field evaluation of yield components of ATPG7 transgenic plants ($T_3$), higher plant height, more of pod number and greater average total seed weight were observed with statistical significance. The results of this study indicate that the introduction of ATPG7 gene in soybean may have the positive effect on yield components.

• 한국자원식물학회지
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• 제34권6호
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• pp.542-554
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• 2021

In this study, we cultivated 115 Soritae and 86 Yakkong black soybean landraces collected from ten different locations in Korea. Then, the variations of three yield components (one-hundred seeds weight (HSW), number of seeds per pod (SPP), and yield per plant (YPP)) and three anthocyanins (cyanidin-3-O-glucoside (C-3-O-G), delphinidin-3-O-glucoside (D-3-O-G) and petunidin-3-O-glucoside (Pt-3-O-G)) were investigated according to landrace type and collection area. Both yield components and anthocyanin contents significantly varied between the soybeans demonstrating genetic differences. Soritae landraces had the highest average HSW and TAC, whereas Yakkong landraces displayed the highest average SPP irrespective of collection area. Relatively, Yakkong landraces from Gyeongsangnam-do (1697.29 mg/100 g) and Soritae landraces from Gyeonggi-do (2340.94 mg/100 g) had the highest average TAC. Principal component analysis clearly separated Soritae and Yakkong landraces. Moreover, TAC and C-3-O-G showed positive and significant associations in both Soritae (r = 0.972) and Yakkong (r = 0.885) landraces, while yield components showed negative or weak correlations with each other. Overall, ten landraces were identified as important resources owing to their high yield (>150 g/plant) and high level of TAC (>2300 mg/100g). This study could lay foundations to molecular level investigations and reinforce the use of Yakkong and Soritae landraces during cultivar development.

• 대한원격탐사학회지
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• 제38권6_2호
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• pp.1653-1661
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• 2022

본 연구에서는 천리안위성 2A호 1일 평균 표층수온영상을 대상으로 합성곱신경망(convolution neural network, CNN) 딥러닝 기법을 적용하여 냉수대 발생 여부를 분류하는 연구를 수행하였다. 이를 위하여, 2019년부터 2022년까지 1,155장의 영상을 사용하였으며, 국립수산과학원 제공 냉수대 발생 주의보 및 경보자료로부터 냉수대 발생 영상과 그 외 영상으로 분류하여 학습을 수행하였다. 학습 결과로 82.5%의 probability of detection (POD)와 54.4%의 false alarm ratio (FAR) 지수를 획득하였다. 오분류 분석을 통해 냉수대 분류에 실패한 경우의 대부분은 구름의 영향 때문이며, 비냉수대를 오분류한 경우의 대부분은 실제 영상에 냉수대가 존재함을 확인하였다.

• 대한조선학회논문집
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• 제58권3호
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• pp.175-181
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• 2021

This study describes the model tests in ice according to the frictional coefficient of an ice-breaking ship and the change in ice resistance by the analysis method for each component of ice resistances. The target vessel is a 90K DWT ice-breaking tanker capable of operating in ARC7 ice conditions in the Arctic Ocean, and twin POD propellers are fitted. The hull was specially painted with four different frictional coefficients on the same ship model. The total ice resistance can be separated by ice breaking, ice buoyancy, ice clearing resistances through the tests in level ice, pre-sawn ice and creep test in pre-sawn ice under sea ice thickness of 1.2 m and 1.7 m. Ice resistance was analyzed by correcting the thickness and bending strength of model ice by the ITTC correction method. As the frictional coefficient between the hull and ice increases, ice buoyancy and clearing resistances increase significantly. When the surface of the hull is rough, it is considered that the broken ice pieces do not slip easily to the side, resulting in an increase in ice buoyancy resistance. Also, the frictional coefficient was found to have a great influence on the ice clearing resistance as the ice thickness became thicker.

• 한국작물학회지
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• 제37권1호
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• pp.54-58
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• 1992

남부지방의 재배 체계 확립을 위한 기초자료를 얻고자 vinyl 피복과 무피복재배하에서 재식밀도 차이에 따른 생육과 수량을 조사했던바 다음과 같은 결과를 얻을 수 있었다. 1. 경장, 경직경, 분지수, m$^2$당 내수, 내당립수 등의 모든 형질이 vinyl 피복구에서 우수하였으며 m$^2$당 내수는 vinyl 피복구에서나 무피복구에서나 60$\times$15cm 재식에서 가장 우수하였다. 2. 천립중과 종실수량 역시 vinyl 피복구에서 높았으며 종실수량은 vinyl 피복과 무피복 모두 60$\times$15cm 재식에서 가장 우수하였다. 3. vinyl 피복과 무피복 상태에서 재식밀도 차이에 따른 농업형질들의 분산분석에서도 유의성이 인정되었다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.158-158
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• 2023

Characterizing the performance of precipitation (hereafter PRE) products in estimating the uncertainties in daily PRE in the era of global warming is of great value to the ecosystem's sustainability and human survival. This study intercompares the performance of different PRE products (gauge-based, satellite and reanalysis) sourced from the Frequent Rainfall Observations on GridS (FROGS) database over diverse climate zones in Africa and identifies regions where they depict minimal uncertainties in order to build optimal maps as a guide for different climate users. This is achieved by utilizing various techniques, including the triple collection (TC) approach, to assess the capabilities and limitations of different PRE products over nine climatic zones over the continent. For daily scale analysis, the uncertainties in light PRE (0.1 5mm/day) are prevalent over most regions in Africa during the study duration (2001-2016). Estimating the occurrence of extreme PRE events based on daily PRE 90th percentile suggests that extreme PRE is mainly detected over central Africa (CAF) region and some coastal regions of west Africa (WAF) where the majority of uncorrected satellite products show good agreement. The detection of PRE days and non-PRE days based on categorical statistics suggests that a perfect POD/FAR score is unattainable irrespective of the product type. Daily PRE uncertainties determined based on quantitative metrics show that consistent, satisfactory performance is demonstrated by the IMERG products (uncorrected), ARCv2, CHIRPSv2, 3B42v7.0 and PERSIANN_CDRv1r1 (corrected), and GPCC, CPC_v1.0, and REGEN_ALL (gauge) during the study period. The optimal maps that show the classification of products in regions where they depict reliable performance can be recommended for various usage for different stakeholders.

• 대한간호학회지
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• 제24권4호
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• pp.545-556
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• 1994

Medical insurance and health care delivery system enabled Korean people to get the necessary medical service, but it caused increased needs for medical service, and resulted in the occurence of some problems such as a lack of manpower and medical facilities. In order to solve these problems, many countries, which already had medical insurance system had developed home care system and it has been regarded effective both in reducing costs and in increasing the rates of turnover of bed. Recently, Korea has included home nursing care in its health care delivery system, and some models of the hospital based home nursing care had been tried and its effects had been evaluated. So, author tried to run a home nursing care for the Cesarean section mothers and evaluate Its effects both in the mother's health and costs. This study was designed as a Quasi-experimental study. Subjects were thirty mothers who got Cesarean section operation in hospital in Seoul. Experimental group consisted of 15 volunteers, and control group were selected by means of matching technique. Data were gathered from February 1st to March 26th by two assistants who were trained by author. Experimental group were discharged on the 4th day after their operation, and got nursing care and assessment about their home three times on the 5th, 6th, and 7th day. Control group stayed in the hospital until 7th day as usual and were checked on the same day as above mentioned To evaluate the state of physiological recovery, vital signs, H.O.F, presence of edema in the legs, bathing, appetite, sleep, presence of pain or discomfort in the breasts, amount of lochia, color of lochia, defecation urination. To compare incidence of complication in experimental group with that in control group, specific assessment was done such variables as smell of lochia, presence of inflammation of operation wound, dizziness, and presence of immobilization in the extremities. The activities of daily living were checked Satisfaction of nursing were checked To calculate costs, author asked subjects to specify expenditure including hospital charge, traffic enpenses, and food expenses. The results were as fellows. 1. On effectiveness of home nursing careThere were n significant differences between experimental and control group in incidence of abnormal symptoms and any complication. The number of taking a bath [POD #5 P=0.001, #6 P=0.0003, #7 P=0.001] and the degree of appetite [POD #5 P=0.03, #6 P=0.02, #7 P=0.013] were significantly higher in experimental group than in control group. Contrary to author's expectation, the degree of the activities of daily living in experimental group was not higher than that of control group. All of the experimental group said they were satisfied with the home nursing care. 2. Cost analysis 1) Hospital charge of experimental group was lower than that of control group. ［P=0.009］ By taking home nursing care, average period of hospitalization was shortened to 3.1 days, and family members could save 22.8 hours. Total amount of money saved by early discharge was 3,443,093 Won. It is estimated that total amount of money saved by early discharge in a year will be 40,398,956 Won. 2) Home nursing care charge of 15 mothers was 1,781,633 Won. It is estimated that total amount of money Saved by it in a year Will be 20,904,493 Won. It was lower altogether than hospital charge of the three days which is 5th, 6th, 7th day of operation. The average cost of single home visit was calculated 10,940 Won. It took 87 minutes per round and it costed 1,017.3 Won. The average hour of home care was 39.0 minutes. 3) It is expected that early discharge can bring forth the increase of hospital income. On the condition that the rate of running bed is 100%, the expected increase of hospital income will be 202,374, 026 Won in a year. Suggestions for further study and nursing practice are as follows : 1. For the welfare of patients and the increased rates of running bed, home nursing care system should be included in the hospital nursing care system. 2. Studies to test effect of home nursing care on the patients with other diseases are needed. 3. Establishment of law on the practice of home nursing care is strongly recommended.