• Nuclear Medicine and Molecular Imaging
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• v.40 no.3
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• pp.177-185
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• 2006

Purpose: Purpose of this study is to synthesize $^{99m}Tc$-labeled transferrin for injection imaging and to compare it with $^{67}Ga$-titrate for the detection of infectious foci. Materials and methods: Succinimidyl 6-hydrazino-nicotinate hydrochloride-chitosan-transferrin (Transferrin) was synthesized and radiolabeled with $^{99m}Tc$. Labeling efficiencies of $^{99m}Tc$-Transferrin were determined at 10 min, 30 min, 1 hr, 2 hr, 4 hr and 8 hr. Biodistribution and imaging studies with $^{99m}Tc$-Transferrin and $^{67}Ga$-citrate were performed in a rat abscess model induced with approximately $2{\times}10^8$ colony forming unit of Staphylococcus aureus ATCC 25923. Results: Successful synthesis of Transferrin was confirmed by mass spectrometry. Labeling efficiency of $^{99m}Tc$-Transferrin was $96.2{\pm}0.7%,\;96.4{\pm}0.5%,\;96.6{\pm}1.0%,\;96.9{\pm}0.5%,\;97.0{\pm}0.7%\;and\;95.5{\pm}0.7%$ at 10 min, 30 min, 1 hr, 2 hr, 4 hr and 8 hr, respectively. The injected dose per tissue gram of $^{99m}Tc$-Transferrin was $0.18{\pm}0.01\;and\;0.18{\pm}0.01$ in the lesion and $0.05{\pm}0.01\;and\;0.04{\pm}0.01$ in the normal muscle, and lesion-to-normal muscle uptake ratio was $3.7{\pm}0.6\;and\;4.7{\pm}0.4$ at 30 min and 3 hr, respectively. On image, lesion-to-background ratio of $^{99m}Tc$-Transferrin was $2.18{\pm}0.03,\;2.56{\pm}0.11,\;3.08{\pm}0.18,\;3.77{\pm}0.17,\;4.70{\pm}0.45\;and\;5.59{\pm}0.40$ at 10 min, 30 min, 1 hr, 2 hr, 4 hr and 10 hr and those of $^{67}Ga$-citrate was $3.06{\pm}0.84,\;4.12{\pm}0.54\;and\;4.55{\pm}0.74 $ at 2 hr, 24 hr and 48 hr, respectively. Conclusion: Transferrin is successfully labeled with $^{99m}Tc$, and its labeling efficiency was higher than 95% and stable for 8 hours. $^{99m}Tc$-Transferrin scintigraphy showed higher image quality in shorter time compared to $^{67}Ga$-citrate image. $^{99m}Tc$-transferrin is supposed to be useful in the detection of the infectious foci.

• Journal of the Korean earth science society
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• v.33 no.6
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• pp.469-480
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• 2012

This study was to analyze the characteristics of diurnal variation of high $PM_{2.5}$ concentration, $PM_{2.5}/PM_{10}$ concentration ratio by spatio-temporal wind system (wind speed and wind direction) for high $PM_{2.5}$ concentration (over the 24 hr environmental standard of $PM_{2.5}$, $50{\mu}g/m^3$) in the air quality observation sites (Jangrimdong: Industrial area, Jwadong: Residential area) that were measured for 3 years (2005. 12. 1-2008. 11. 30) in Busan. The observation days of high $PM_{2.5}$ concentration were 182 at Jangrimdong and 27 at Jwadong. The seasonal diurnal variation of hourly mean of high $PM_{2.5}$ concentration and of $PM_{2.5}/PM_{10}$ concentration ratio showed a similar pattern that had higher variation at dawn, and night and in the morning than in the afternoon. Durning daytime in summer at Jwadong, the $PM_{2.5}/PM_{10}$ concentration ratio increased because a secondary particulate matter, which was created by photochemical reaction, decreased the coarse particles of $PM_{10}$ more than the fine particles of $PM_{2.5}$ concentrations in ocean condition. We did an analysis of spatio-temporal wind system (wind speed range and wind direction) in each time zone. The result showed that high $PM_{2.5}$ concentration at Jangrimdong occurred due to the congestion of pollutants emissions from the industrial complex in Jangrimdong area and the transportation of pollutants from places nearby Jangrimdong. It also showed that high $PM_{2.5}$ concentration occurred at Jwadong because of a number of local residential and commercial activities that caused the congestion of pollutants.

• Korean Journal of Soil Science and Fertilizer
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• v.48 no.4
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• pp.295-304
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• 2015

To develop a technique for efficient management of fertility for cucumber in greenhouse, a quick test method to quantify nitrate ($NO_3{^-}$) content in soil solution and leaf petiole juice using a simple instrument that are easy to use for farmers was investigated. N fertilizer (urea) was applied at 0, 50, 100 and 200% levels of the recommended application rate from 30 days after transplanting to harvest by soil fertigation treatments. Stable results were obtained from analysis of nitrate ($NO_3{^-}$) using top $10^{th}$ or $11^{th}$ leaf petioles collected between 10 to 11 am in the morning. Under the semiforcing culture, $NO_3{^-}$ content of leaf petiole juice was highest at 60 days after transplanting (DAT) at all fertigation treatments. Appropriate $NO_3{^-}$content of leaf petiole juice was $2,418{\pm}78{\sim}2,668{\pm}118$ at 45 DAT, $3,032{\pm}90{\sim}3,332{\pm}63$ at 60 DAT, $2,709{\pm}50{\sim}3,158{\pm}155$ at 75 DAT, $2,535{\pm}49{\sim}2,907{\pm}83$ at 90 DAT, and $2,242{\pm}48mg\;L^{-1}$ at 105 DAT. In addition, appropriate $NO_3{^-}$ content of soil solution was $167{\pm}9{\sim}212{\pm}15$ at 45 DAT, $83{\pm}10{\sim}112{\pm}12$ at 60 DAT, $49{\pm}3{\sim}92{\pm}6$ at 75 DAT, $71{\pm}9{\sim}103{\pm}9$ at 90 DAT, and $73{\pm}9mg\;L^{-1}$ at 105 DAT. The cucumber yield at 100% N level of fertigation was $7,770kg\;10a^{-1}$ and no difference in yield was found at 200% N level of fertigation. However, there was 12% decrease in yield at 50% N fertigation and, 17% decrease at 0% N fertigation. Under retarding culture, $NO_3{^-}$ concentration of leaf petiole juice was highest at 55 days after transplanting (DAT) at all fertigation treatments. Appropriate $NO_3{^-}$ content of leaf petiole juice was $2,464{\pm}102{\sim}2,651{\pm}33$ at 45 DAT, $3,025{\pm}71{\sim}3,314{\pm}84$ at 55 DAT and $2,488{\pm}92mg\;L^{-1}$ at 65 DAT, respectively. Appropriate $NO_3{^-}$ content of soil solution was $111{\pm}10{\sim}155{\pm}14$ at 45 DAT, $93{\pm}7{\sim}147{\pm}14$ at 55 DAT, $67{\pm}4mg\;L^{-1}$at 65 DAT, respectively. The cucumber yield at 50% N fertigation was not different from $1,697kg\;10a^{-1}$ of 100% N fertigation level and even with that of the 200% N fertigation. However, there was 21% decrease in yield at 0% N fertigation.

• Journal of Korean Society for Atmospheric Environment
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• v.18 no.5
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• pp.419-426
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• 2002

The concentrations of three different fractions of particulate matters including PM2.5, PM10, and TSP were compared between the Asian Dust (AD) and non-AD (NAD) periods during the spring season of 2001. For the purpose of this comparative analysis, the data sets were obtained from four different observatory sites located within the city boundary of Seoul that concurrently measure those three fractions of PM at hourly intervals. According to our study, several conclusions can be drawn to describe relationships between the AD event and PM distribution characteristics. First of all, it is apparent that the concentrations of PM are distinctively distinguished between AD and NAD. If the extent of contribution to the AD events are assessed on the quantitative basis, it appears that their magnitude increases on the order of PM2.5, PM10, and TSP. As a result, the increase of PM observed during AD event is dominated by the coarse rather than fine fraction of PM. Moreover, when their relationships were assessed in terms of fractional ratios, it was found that TSP/PM10 ratios were almost constant, regardless of the occurrences of AD. On the other hand, the coarse/fine or TSP/PM2.5 ratios changed dramatically between AD and NAD periods. The results of our analysis cleary distinguishes quantitative role of each PM fraction between AD and NAD period, while suggesting indirectly the possible control of source processes on such relationships.

• Journal of Wetlands Research
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• v.11 no.2
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• pp.47-54
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• 2009

This study was conducted to consider the characteristics of PM10(particulate matter with aerodynamic diameters less than 10 ${\mu}m$) concentration according to land-use in Busan coastal area. Fine particle is affected by emissions, geographical conditions and meteorological factors. In case industrial area, Gamjeondong(inland) PM10 concentration was higher than Noksandong(seashore) at all season except for Summer. Primary peak at Gamjeondong cleared than Noksandong in Fall and Winter. In case green area, Daejeodong(inland) PM10 concentration was higher than Dongsamdong(seashore) at all seasons. In case commercial area, primary peak occurrence time at Jeonpodong lagged one hour according to season and diurnal change of PM10 concentration at Gwangbokdong was higher than Jeonpodong in Spring. In case residential area, high PM10 concentration(80~90 ${\mu}g/m^3$) lasted for six hours during the daytime in Spring at Deogcheondong and Yongsuri(inland).

• Korean Journal of Remote Sensing
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• v.36 no.6_3
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• pp.1691-1710
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• 2020

We measured PM2.5 and PM10 (particulate matter less than 2.5 ㎛ and 10 ㎛ in diameter, respectively) simultaneously at 16 locations around an elementary school and classrooms in Busan and Pyeongtaek, South Korea. In this study, we compared the results of this field intensive with those in the literature (144 cases of 30 studies), focusing on I/O (Indoor/Outdoor) ratios. We also reviewed the results of previous studies, categorizing them into related sub-categories for indoor-activities, seasons, building-uses, and the surrounding environment. We conclude that indoor PM10 is affected more by indoor-sources (e.g., physical activities) than PM2.5 in the absence of combustion sources like smoking and cooking. Additionally, PM10 and PM2.5 likely have different indoor-outdoor infiltration efficiencies. Conclusively, PM10 in classrooms can be more sensitively affected by both indoor activities and ambient concentrations, and mechanical ventilation can be more efficient in reducing PM concentrations than natural ventilation.

• Journal of Environmental Science International
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• v.12 no.10
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• pp.1033-1041
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• 2003

Hourly data of PM10 concentration collected from nine automatic air quality monitoring stations in Busan from 1999 to 2002 were analyzed to evaluate the spatio-temporal variation and meteorological characteristics of PM10 episodes in Busan metropolitan area. Mean concentrations ranged from 47$\mu\textrm{g}$/㎥ to 77$\mu\textrm{g}$/㎥. For most stations, mean seasonal hourly concentrations are lowest in summer and highest in spring. PM10 episode above daily mean standard(150$\mu\textrm{g}$/㎥) exhibited a maximum frequency at Gamjeondong and a minimum at Dongsamdong, and a maximum in March and a minimum in July and August. The diurnal variation of PM10 episode days is strongly influenced by traffic loads and meteorological conditions.

• Korean Journal of Veterinary Research
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• v.28 no.2
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• pp.279-284
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• 1988

Observations were made on the blood picture of 50 multiparous and 98 infertile cows. The results obtained in this study were summarized as follows. 1. Mean values of RBC, Hb, PCV, MCV, MCH, MCHC and platelets for normal multiparous cows were $6.87{\pm}0.84{\times}10^6/mm^3$, $10.3{\pm}1.3g/100ml$, $31.4{\pm}3.7ml/100ml$, $46.1{\pm}6.9{\mu}^3$, $15.3{\pm}2.6pg$, $34{\pm}2.7%$, and $372.7{\pm}304.7{\times}10^3/mm^3$ respectively. 2. Mean values of RBC, Hb, PCV, MCV, MCH, MCHC and platelets for infertile cows were $7.00{\pm}0.98{\times}10^6/mm^3$, $10.6{\pm}1.2g/100ml$, $32.1{\pm}3.6ml/100ml$, $45.8{\pm}6.7{\mu}^3$, $15.3{\pm}1.8pg$, $33.9{\pm}3.3%$, and $382.7{\pm}157.5{\times}10^3/mm^3$, respectively. 3. Mean values of WBC count for normal multiparous and infertile cows were $7.92{\pm}1.72$ and $9.04{\pm}2.87{\times}10^3/mm^3$ respectively. 4. In the differential leukocytes count, mean values of neutrophils, lymphocytes, monocytes, eosinophils and basophils for normal multiparous cows were $29.7{\pm}7.9%$, $56.8{\pm}7.6%$, $2.9{\pm}1.9%$, $9.9{\pm}5.3%$ and $0.3{\pm}0.7%$, respectively, and mean values of neutrophils, lymphocytes, monocytes, eosinophils and basophils for infertile cows were $31.9{\pm}7.8%$, $57.5{\pm}7.9%$, $2.6{\pm}1.9%$, $7.5{\pm}4.8%$, and $0.4{\pm}0.2%$, respectively.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2001.11a
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• pp.329-330
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• 2001

대기오염물질은 입자상물질과 가스상물질로 구분되는데, 이 중 입자상물질은 시정을 감소시키고 인체 건강에 유해한 영향을 미친다. 일반적으로 입자크기가 큰 거대입자는 인체 호흡기관에서 대부분 차단되거나 다시 밖으로 나오게 되지만, 입자크기가 작은 미세입자의 경우 대부분 폐의 깊은 곳에 침착하여 인체에 매우 유해하다. 이러한 미세입자의 유해성 때문에 우리나라도 1995년부터 PM10에 대한 대기환경기준을 설정하여 그 양을 규제하고 있다. 최근에는 폐에 높은 침착률을 보이는 PM2.5에 대한 관심이 집중되고 있다. (중략)

• Particle and aerosol research
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• v.7 no.2
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• pp.59-68
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• 2011

The objective of the study was to investigate the main factors that contribute the variation of $PM_{10}$ concentration of Seoul and to quantify their effects using generalized additive model (GAM). The analysis was performed with 3 year air pollution data (2004~2006) measured at 27 urban sites and 7 roadside sites in Seoul, a background site in Gangwha and a rural site in Pocheon. The diurnal variation of urban $PM_{10}$ concentrations of Seoul showed a typical bimodal pattern with the same peak times as that of roadside, and the maximum difference of $PM_{10}$ level between urban and roadside was about $14{\mu}g/m^{3}$ at 10 in the morning. The wind direction was found to be a major factor that affects $PM_{10}$ level in all investigated areas. The overall $PM_{10}$ level was reduced when air came from east, but background $PM_{10}$ level in Gangwha was rather higher than the urban $PM_{10}$ level in Seoul, indicating that the $PM_{10}$ level in Gangwha is considerably influenced by that in Seoul metropolitan area. When hourly variations of $PM_{10}$ were analyzed using GAM, wind direction and speed explained about 34% of the variance in the model where the variables were added as a 2-dimensional smoothing function. In addition, other variables, such as diurnal variation, difference of concentrations between roadside and urban area, precipitation, month, and the regression slope of a plot of carbon monooxide versus $PM_{10}$, were found to be major explanatory variables, explaining about 64% of total variance of hourly variations of $PM_{10}$ in Seoul.