• Title/Summary/Keyword: PLP-A

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Estimation of Tire-Pavement Noise for Asphalt Pavement by Mean Profile Depth (Mean Profile Depth를 이용한 아스팔트 포장의 타이어-노면소음 산정 연구)

  • Hyun, Tak Jib;Hong, Seong Jae;Kim, Hyung Bae;Lee, Seung Woo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.4
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    • pp.1631-1638
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    • 2013
  • Distress data, IRI, etc. are important factors in the evaluation of pavement condition. Recently, the need to consider tire-pavement noise in PMS (pavement management system) is raised. Generally, tire-pavement noise highly depends on the characteristics of pavement texture. Therefore, estimation of texture characteristics may give useful information to predict tire-pavement noise. Measurement of MPD (Mean Profile Depth) by using PLP (Portable Laser Profiler) provide very fast. The texture characteristics by means of MPD can be in a short time. hence, It can be a good alternative to give noise information, if MPD and tire-pavement noise have robust relationship. In this study, MPD and tire-pavement noise were simultaneously collected on the number of asphalt section to evaluate the tire-pavement noise due to the pavement texture characteristics. A set of statistical analysis was performed to propose relationship between tire-pavement noise and MPD for asphalt concrete pavement.

Human brain pyridoxal-5'-phosphate phosphatase (PLPP): protein transduction of PEP-1-PLPP into PC12 cells

  • Lee, Yeom-Pyo;Kim, Dae-Won;Lee, Min-Jung;Jeong, Min-Seop;Kim, So-Young;Lee, Sun-Hwa;Jang, Sang-Ho;Park, Jin-Seu;Kang, Tae-Cheon;Won, Moo-Ho;Cho, Sung-Woo;Kwon, Oh-Shin;Eum, Won-Sik;Choi, Soo-Young
    • BMB Reports
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    • v.41 no.5
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    • pp.408-413
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    • 2008
  • Pyridoxal-5'-phosphate phosphatase (PLPP) catalyzes the dephosphorylation of pyridoxal-5'-phosphate (PLP). A human brain PLPP gene was fused with a PEP-1 peptide and produced a genetic in-frame PEP-1-PLPP fusion protein. The purified PEP-1-PLPP fusion protein was efficiently transduced into PC12 cells in a time- and dose-dependent manner when added exogenously to culture media. Once inside the cells, the transduced PEP-1-PLPP fusion protein was stable for 36 h. The concentration of PLP was markedly decreased by the addition of exogenous PEP-1-PLPP to media pretreated with the vitamin $B_6$ precursors; pyridoxine, pyridoxal kinase and pyridoxine-5'-phosphate oxidase into cells. The results suggest that the transduction of the PEP-1-PLPP fusion protein can be one mode of PLP level regulation, and to replenish this enzyme in the various neurological disorders related to vitamin $B_6$.

Analysis of Feature Extraction Methods for Distinguishing the Speech of Cleft Palate Patients (구개열 환자 발음 판별을 위한 특징 추출 방법 분석)

  • Kim, Sung Min;Kim, Wooil;Kwon, Tack-Kyun;Sung, Myung-Whun;Sung, Mee Young
    • Journal of KIISE
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    • v.42 no.11
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    • pp.1372-1379
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    • 2015
  • This paper presents an analysis of feature extraction methods used for distinguishing the speech of patients with cleft palates and people with normal palates. This research is a basic study on the development of a software system for automatic recognition and restoration of speech disorders, in pursuit of improving the welfare of speech disabled persons. Monosyllable voice data for experiments were collected for three groups: normal speech, cleft palate speech, and simulated clef palate speech. The data consists of 14 basic Korean consonants, 5 complex consonants, and 7 vowels. Feature extractions are performed using three well-known methods: LPC, MFCC, and PLP. The pattern recognition process is executed using the acoustic model GMM. From our experiments, we concluded that the MFCC method is generally the most effective way to identify speech distortions. These results may contribute to the automatic detection and correction of the distorted speech of cleft palate patients, along with the development of an identification tool for levels of speech distortion.

Recognition of Restricted Continuous Korean Speech Using Perceptual Model (인지 모델을 이용한 제한된 한국어 연속음 인식)

  • Kim, Seon-Il;Hong, Ki-Won;Lee, Haing-Sei
    • The Journal of the Acoustical Society of Korea
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    • v.14 no.3
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    • pp.61-70
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    • 1995
  • In this paper, the PLP cepstrum which is close to human perceptual characteristics was extracted through the spread time area to get the temperal feature. Phonemes were recognized by artificial neural network similar to the learning method of human. The phoneme strings were matched by Markov models which well suited for sequence. Phoneme recognition for the continuous Korean speech had been done using speech blocks in which speech frames were gathered with unequal numbers. We parameterized the blocks using 7th order PLPs, PTP, zero crossing rate and energy, which neural network used as inputs. The 100 data composed of 10 Korean sentences which were taken from the speech two men pronounced five times for each sentence were used for the the recognition. As a result, maximum recognition rate of 94.4% was obtained. The sentence was recognized using Markov models generated by the phoneme strings recognized from earlier results the recognition for the 200 data which two men sounded 10 times for each sentence had been carried out. The sentence recognition rate of 92.5% was obtained.

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Quality Characteristics of White Pan Bread Added with Perilla Leaf Powder (들깻잎 분말을 첨가한 식빵반죽의 레올로지 및 품질 특성에 관한 연구)

  • Choi, Sang-Ho
    • Culinary science and hospitality research
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    • v.17 no.3
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    • pp.172-180
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    • 2011
  • This study explores the quality characteristics of white pan bread added with perilla leaf powder, and the results are as follows. The WRC(water retention capacity) of PLP (perilla leaf powder) added to the bread dough increased as the addition increased, and the initiation temperature during the rapid visco analysis (RVA) increased with more additions, showing significant differences. The highest and the lowest viscosity of the sample decreased as the powder added increased. The brightness(L value) of the bread without the powder was the highest, and the redness (a value) and the yellowness (b value) showed significant differences among the samples. Hardness increased showing significant differences among the samples as the powder added increased Chewiness was the highest but preference value was the lowest in the sample with 7% of the powder. The lowest score was shown in the color of the sample with the most PLP added. Flavor was the lowest of 4.93 in the comparison sample without the leaf powder added while bitter taste scored the highest of 5.21 in the sample of 3% powder added. It was also the highest in overall acceptance while the sample with the most powder showed the lowest of 4.03. From these results, it can be said that the preference of bread with PLP seems to decrease when more than 5% of PLP is added.

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Effect of in vitro B-6 Vitameric Forms on Lymphocyte Proliferation in Healthy Young Women with Oral Vitamin B-6 Supplementation

  • Kwak Ho Kyung;Leklem James E.
    • Journal of Community Nutrition
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    • v.7 no.2
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    • pp.79-84
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    • 2005
  • A vitamin B-6 (B-6) intake higher than the current Recommended Dietary Allowance (RDA) has been found to provide an improvement in immune system. Seven premenopausal women consumed their usual diet with the exception of foods relatively high in vitamin B-6 for a total of 27 d. After 7 d, all subjects received a multivitamin supplement containing 2mg B-6 and 4 subjects were given an additional 50mg of B-6 supplement for 20 d. Lymphocyte response to phytohemagglutinin (PHA) was measured before and after the supplementation. To determine the effect of different forms of B-6 on lymphocyte proliferation, cell culture media supplemented with pyridoxal (PL) and PLP, as well as B-6 free media, were tested. A 50mg B-6 supplement significantly increased vitamin B-6 status. There was no further enhancement on lymphocyte proliferation when subjects were taking an additional 50mg of vitamin B-6 supplement. In general, lymphocyte proliferation in media with either PLP or PL did not show any prominent difference. These [m-dings suggest that there may be no further benefits of a B-6 dose beyond twice that of the current RDA on lymphocyte proliferation. Further studies are necessary to examine the effect of the B-6 intake level on activities of enzymes involved in cellular B-6 metabolism in lymphocytes to provide substantial insight into the mechanisms underlying the role of B-6 in the lymphocyte proliferation.

Characterization of Endopeptidase of Bacillus amyloliquefaciens S94 by Chemical Modificationtion (Bacillus amyloliquefaciens에서 분리된 단백질 가수분해 효소의 화학적 수식에 의한 저해양상 분석)

  • Kim, Jong-Il
    • Korean Journal of Microbiology
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    • v.39 no.4
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    • pp.230-234
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    • 2003
  • An extracellular protease of Bacillus amyloliquefaciens S94 was purified to apparent homogeneity. The enzyme activity was strongly inhibited by general inhibitor for serine protease, PMSF, suggesting that the enzyme is a serine protease. The purified enzyme activity was inhibited by leucine peptidase inhibitor, bestatin, suggesting that the enzyme is a leucine endopeptidase. When the enzyme was chemically modified with PMSF, which specifically reacted with serine residue on the enzyme, the activity was eliminated. The endopeptidase activity was inhibited by the modifier which chemically modified carboxyl group of aspartate and glutamate. PLP, which would modify lysine residue, did not affect the endopepetidase activity to a greater extent. This demonstrates that serine and aspartate (or glutamate) residues of enzyme would participate in a important function of the endopeptidase activity.

A Study on the Features for Building Korean Digit Recognition System Based on Multilayer Perceptron (다층 퍼셉트론에 기반한 한국어 숫자음 인식시스템 구현을 위한 특징 연구)

  • 김인철;김대영
    • Journal of Korea Society of Industrial Information Systems
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    • v.6 no.4
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    • pp.81-88
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    • 2001
  • In this paper, a Korean digit recognition system based on a multilayer Perceptron is implemented. We also investigate the performance of widely used speech features, such as the Mel-scale filterbank, MFCC, LPCC, and PLP coefficients, by applying them as input of the proposed recognition system. In order to build a robust speech system, the experiments for demonstrating its recognition performance for the clean data as well as corrupt data are carried out. In experiments of recognizing 20 Korean digit, we found that the Mel-scale filterbank coefficients performs best in terms of recognition accuracy for the speech dependent and speech independent database even though noise is considerably added.

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Vitamin B6 Deficiency, Genome Instability and Cancer

  • Wu, Xia-Yu;Lu, Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5333-5338
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    • 2012
  • Vitamin B6 functions as a coenzyme in >140 enzymatic reactions involved in the metabolism of amino acids, carbohydrates, neurotransmitters, and lipids. It comprises a group of three related 3-hydroxy-2-methyl-pyrimidine derivatives: pyridoxine (PN), pyridoxal (PL), pyridoxamine (PM) and their phosphorylated derivatives [pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP)], In the folate metabolism pathway, PLP is a cofactor for the mitochondrial and cytoplasmic isozymes of serine hydroxymethyltransferase (SHMT2 and SHMT1), the P-protein of the glycine cleavage system, cystathionine ${\beta}$-synthase (CBS) and ${\gamma}$-cystathionase, and betaine hydroxymethyltransferase (BHMT), all of which contribute to homocysteine metabolism either through folate-mediated one-carbon metabolism or the transsulfuration pathway. Folate cofactors carry and chemically activate single carbons for the synthesis of purines, thymidylate and methionine. So the evidence indicates that vitamin B6 plays an important role in maintenance of the genome, epigenetic stability and homocysteine metabolism. This article focuses on studies of strand breaks, micronuclei, or chromosomal aberrations regarding protective effects of vitamin B6, and probes whether it is folate-mediated one-carbon metabolism or the transsulfuration pathway for vitamin B6 which plays critical roles in prevention of cancer and cardiovascular disease.

A Study on Image Recommendation System based on Speech Emotion Information

  • Kim, Tae Yeun;Bae, Sang Hyun
    • Journal of Integrative Natural Science
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    • v.11 no.3
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    • pp.131-138
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    • 2018
  • In this paper, we have implemented speeches that utilized the emotion information of the user's speech and image matching and recommendation system. To classify the user's emotional information of speech, the emotional information of speech about the user's speech is extracted and classified using the PLP algorithm. After classification, an emotional DB of speech is constructed. Moreover, emotional color and emotional vocabulary through factor analysis are matched to one space in order to classify emotional information of image. And a standardized image recommendation system based on the matching of each keyword with the BM-GA algorithm for the data of the emotional information of speech and emotional information of image according to the more appropriate emotional information of speech of the user. As a result of the performance evaluation, recognition rate of standardized vocabulary in four stages according to speech was 80.48% on average and system user satisfaction was 82.4%. Therefore, it is expected that the classification of images according to the user's speech information will be helpful for the study of emotional exchange between the user and the computer.