• Microbiology and Biotechnology Letters
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• v.51 no.4
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• pp.484-499
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• 2023

Plant growth-promoting (PGP) bacteria can be used as bioresources to enhance phytoremediation through their PGP traits and pollutant removal capacity. In this study, 49 rhizobacteria were primarily isolated from the rhizosphere of tall fescue grown in diesel- and heavy metal-contaminated soil. Their biosurfactant production, phosphate (P) solubilization, and siderophore production were qualitatively and quantitatively evaluated to identify superior PGP bacteria. The optimal conditions for the growth of PGP bacteria and the stability of their PGP traits were a temperature of 35℃, a pH of 7, and 2 days of cultivation time. Four superior PGP bacteria (Pseudomonas sp. NL3, Bacillus sp. NL6, Bacillus sp. LBY14, and Priestia sp. TSY6) were finally selected. Pseudomonas sp. NL3 exhibited superior biosurfactant production and P solubilization. Bacillus sp. NL6 showed the highest P solubilization and superior production of biosurfactants and siderophores. Bacillus sp. LBY14 offered the best siderophore production and impressive P solubilization. Priestia sp. TSY6 had superior capacity for all three PGP traits. Through their secretion of beneficial PGP metabolites, the four bacteria isolated in this study have the potential for use in the phytoremediation of contaminated soil.

• Journal of Korea Multimedia Society
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• v.23 no.8
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• pp.1030-1039
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• 2020

The biggest feature of the online environment is anonymity. So it is difficult to identify the sender accurately in Email. So we use PGP to enhance the security of email. PGP is an e-mail encryption program that has become the standard for email security worldwide. But PGP has a weak point in security. PGP can identify users, but it is difficult to verify reliability. In PGP, the more reliable other users guarantee that user are, the more reliable they are. In the previous study, the PGP structure was implemented by utilizing the block chain to lay the foundation, and in this paper, the structure of the previous article is applied to the e-mail environment to measure up the sender's reliability, and a system is proposed that allows users to distinguish the reliability of the message.

• Journal of Korea Multimedia Society
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• v.23 no.5
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• pp.658-666
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• 2020

PGP is an encryption software designed to provide information protection, security and authentication services for online communication systems. The characteristic of behavior done on the Internet is that you don't know the other person. It is very important to protect information from someone you cannot trust. So identification of the other person is an important task. PGP uses an digital signature algorithm to verify the identity of the other party. However, it is not accurate to check the other party's credibility. PGP increases trust as other users sign more on public keys of user. In other words, credibility is not perfect. In this paper, PGP certification system that key management in Ethereum blockchain, one of the blockchain platforms, is proposed. Key management in blockchain ensures data integrity, transparency and reliability.

• Review of KIISC
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• v.5 no.4
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• pp.58-90
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• 1995

PGP(Pretty Good Privacy)는 전자우현에 사용되는 보안도구로써 현재 인터넷(Internet)상에서 광범위하게 사용되고 있다. 전자우편에서 필요로 하는 기밀성, 무결성, 송신자 인증, 송신부인방지등의 기능을 모두 제공해 주고 있고 특히, 사용되는 키에 대한 인증을 하나의 기관에서 전담하지 않고, PGP의 사용자들에 의한 키 인증방식을 채택하고 있는 것이 특징이다. 본고에서는 PGP의 효과적인 보급을 위해 전자우편에 필요한 기본 암호 메카니즘과 PGP의 구조 및 사용방법을 살펴본다.

• 대한핵의학회:학술대회논문집
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• 2001.05a
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• pp.66-75
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• 2001

Although diverse mechanisms are involved in multidrug resistance for chemotherapeutic drugs, the development of cellular P-glycoprotein(Pgp) and multidrug-resistance associated protein (MRP) are important factors in the chemotherapy failure to cancer. Various detection assays provide information about the presence of drug efflux pumps at the mRNA and protein levels. However these methods do not yield information about dynamic function of Pgp and MRP un vivo. Single photon emission tomography (SPECT) and positron emission tomography (PET) are available for the detection of Pgp and MRP-mediated transport. $^{99m}Tc$-sestaMIBl and other $^{99m}Tc$-radiopharmaceuticals are substrates for Pgp and MRP, and have been used in clinical studies for tumor imaging, and to visualize blockade of Pgp-mediated transport after modulation of Pgp pump. Colchicine, verapamil and daunorubicin labeled with $^{11}C$ have been evaluated for the quantification of Pgp-mediated transport with PET in vivo and reported to be feasible substrates with which to image Pgp function in tumors. Leukotrienes are specific substrates for MRP and N-$[^{11}C]$acetyl-leukotriene E4 provides an opportunity to study MRP function non-invasively in vivo. Results obtained from recent publications are reviewed to confirm the feasibility of using SPECT and PET to study the functionality of MDR transporters in vivo.

• Bulletin of the Korean Chemical Society
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• v.32 no.10
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• pp.3666-3674
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• 2011

Overexpression of P-glycoprotein (Pgp) is associated with multidrug resistance (MDR) of tumor cells to a number of chemotherapeutic drugs. Pgp inhibitors have been shown to effectively reverse Pgp-mediated MDR. We prepared a series of phenoxy-N-phenylacetamide derivatives and tested for their ability to inhibit Pgp as potential MDR reversing agents, using a Pgp over-expressing MCF-7/ADR cell line. Some of the synthesized compounds exhibited moderate to potent reversal activity. Of note, compound 4o showed a 3.0-fold increased inhibition compared with verapamil, a well-known Pgp inhibitor. In addition, co-treatment of the representative compound 4o and a substrate anticancer agent doxorubicin resulted in a remarkable increase in doxorubicin's antitumor effect and inhibition of DNA synthesis in the MCF-7/ADR cell line. Taken together, these findings suggest that compound 4o could be a useful lead for development of a novel Pgp inhibitor for treatment of MDR.

• Proceedings of the Korea Multimedia Society Conference
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• 2004.05a
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• pp.91-94
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• 2004

정보통신의 급속한 발전은 유무선 네트워크 및 컴퓨팅 환경에 대한 다양한 서비스를 제공하고 있다 이중 가장 전자우편 서비스와 관련하여 현실적인 보안 취약성을 보완하기 위한 여러 가지 보안 서비스가 개발되고 제공되고 있다. 따라서 본 논문에서는 대표적인 전자우편 서비스인 PGP, PGP/MIME, OpenPGP에 대한 표준화에 대해 분석하고, 전자우편 서비스를 국내에 적용하기 위한 가이드라인을 제시하고자 한다.

• Toxicological Research
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• v.25 no.1
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• pp.29-33
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• 2009

Phellinus gilvus (PG) is a widely used mushroom for health promotion. We studied the hepatoprotective effect of the polysaccharide aqueous extract of PG (PGP) against carbon tetrachloride ($CCl_4$)-induced liver injury in rats. Sprague Dawley rats were divided into 5 groups: Normal control, $CCl_4$ control, PGP 50, 100, and 200 mg/kg + $CCl_4$. The levels of serum biochemical parameters, liver lipid peroxide and antioxidant enzymes, and histological appearances were evaluated. The $CCl_4$-induced increments of alanine aminotransferase, asparate aminotransferase, and alkaline phosphatase levels in serum were significantly decreased by PGP-pretreatments. The PGP dose-dependently decreased hepatic malondialdehyde formations in $CCl_4$-treatment groups. Hepatic antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) were elevated by PGP in $CCl_4$-treatment groups. Histopathological evaluation of liver showed that the loss of hepatocytes, fatty changes, swelling and extensive necrosis of hepatocytes in centrilobular regions of the $CCl_4$-treated rats were ameliorated by PGP pretreatment. The PGP has hepatoprotective and antioxidative effects in $CCl_4$-induced liver injury of rat.

• Journal of Microbiology and Biotechnology
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• v.9 no.3
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• pp.318-322
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• 1999

A new baculovirus transfer vector (pPGP404) was constructed to increase the expression level of human thrombopoietin (hTPO) in insect cells. In pPGP404, hTPO was cloned next to the AcNPV polyhedrin-gp64 dual promoter and the leader sequence of hTPO was substituted with that of gp64. A recombinant baculovirus, AcPGP404, was constructed by using pPGP404 as a transfer vector. hTPO was expressed in AcPGP404-infected TN5 cells and it was observed that the expression levels of hTPO in TN5 cells increased three-fold ($6.0 {\mu}g/ml^{-1}$) compared to the level expressed under the control of the polyhedrin single promoter. These results indicate that the polyhedrin-gp64 dual promoter system would be useful for expression in large quantities of recombinant proteins in insect cells.

• The Plant Pathology Journal
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• v.38 no.5
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• pp.490-502
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• 2022

Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial leaf blight (BLB) disease in rice (Oryza sativa L.) and it is among the most destructive pathogen responsible for severe yield losses. Potential bacterial biocontrol agents (BCAs) with plant growth promotion (PGP) abilities can be applied to better manage the BLB disease and increase crop yield, compared to current conventional practices. Thus, this study aimed to isolate, screen, and identify potential BCAs with PGP abilities. Isolation of the BCAs was performed from internal plant tissues and rhizosphere soil of healthy and Xoo-infected rice. A total of 18 bacterial strains were successfully screened for in vitro antagonistic ability against Xoo, siderophore production and PGP potentials. Among the bacterial strains, 3 endophytes, Bacillus sp. strain USML8, Bacillus sp. strain USML9, and Bacillus sp. strain USMR1 which were isolated from diseased plants harbored the BCA traits and significantly reduced leaf blight severity of rice. Simultaneously, the endophytic BCAs also possessed plant growth promoting traits and were able to enhance rice growth. Application of the selected endophytes (BCAs-PGP) at the early growth stage of rice exhibited potential in suppressing BLB disease and promoting rice growth.