• Journal of the Society of Naval Architects of Korea
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• v.42 no.4 s.142
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• pp.315-321
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• 2005

The effect of water depth on the wave making resistance performance is great where Froude number based on the water depth is close to one. The increase of wave making resistance due to the shallow water effect is evaluated by a numerical analysis in the present study. Three-dimensional Navier-Stokes and continuity equations are employed for the present study and the equations are discretized by finite difference method. The interface between water and air is determined by the level set method. In order to validate the numerical method, the change of resistance performance for Wigley hull according to the water depth is evaluated and the computed resistance coefficient is compared with measured one. The present numerical method is applied for the simulation of wave phenomena around a Ro-Pax hull form and the computed results are discussed in the resistance performance point of view.

• 수도
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• v.22 no.5 s.75
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• pp.76-92
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• 1995

• Korean Architects
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• no.11 s.463
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• pp.32-33
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• 2007

• KSBB Journal
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• v.13 no.3
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• pp.272-278
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• 1998

Cell recovery from high cell density broths of Alcaligenes eutrophus by pretreatment with aluminum-based coagulants such as aluminum sulfate, polyaluminum hydrooxide chloride silicate (PACS), and polyaluminum hydrooxide chloride (Hi-PAX) was carried out. Cells coagulated with coagulants could be successfully recovered above 95-99% by centrifugation or filtration. The optimum initial pH of fermentation broths for cell recovery was in the range of 10 to 12. Optimum coagulants dosage for cell recovery increased with increasing of cell concentrations (21-160 g/L). The optimum coagulant dosages to recover cells with more than 95% cell recovery by centrifugation for the cell concentrations ranged 21-160 g/L were as follows: aluminum sulfate, 416-1708 mg Al/L; PACS, 211-826 mg Al/L; Hi-PAX, 320-960 mg Al/L. At optimum conditions for the coagulation of cells, centrifugal forces for 95% of cell recovery were dependent on the cell concentration. The centrifugal forces at 82 g/L and 160 g/L of cell concentration were only 45${\times}$g and 1600${\times}$g, respectively.

• Journal of the Society of Naval Architects of Korea
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• v.41 no.6
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• pp.114-119
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• 2004

For passenger vessels, twin shaft types in propulsion system is generally adopted to provide a high-speed performance in low draught due to restricted operating condition in harbors or water channels. Struts of twin open shaft type support the shafts, bearings, and propellers. Therefore, strut design is needed to consider not only hydrodynamic performance but also structural and noise/vibration performance, In this paper, considerations in strut design at the initial design stage have been discussed based on existing references, numerical calculations, and their comparisons. Also, the strut design of a RoPax ferry has been carried out at the initial design stage, for an example.

• Strategy21
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• s.36
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• pp.59-93
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• 2015

A Paradigm shift is in process in China's foreign policies during Xi Jinping's era. Such changes occur with changing national identities from developing country to great power, and from continental power to continental-maritime power. China's pursuit for sea power embraces its global strategy. Accommodating the new identity of maritime power, China is developing its maritime strategy. New silk-road strategy actively utilizes China's advantage in economy, while avoiding direct military challenges against the U.S. China seeks an associated balance of power with the U.S. On the other hand, China make its determination clear to protect its core national interests, particularly Taiwan straits issue, deploying Anti-Access and Area-Denial strategy. 'Pax-Americana 3.0' and 'China's rise 2.0' have convoluted and evolved in complexity. South Korea faces much tougher challenges ahead in its foreign and security environments.

• Proceedings of the Korean Society of Environment and Ecology Conference
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• 2006.10a
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• pp.191-194
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• 2006

• Journal of the Society of Naval Architects of Korea
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• v.49 no.6
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• pp.491-497
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• 2012

A hull-form for a 32,000G/T class Ro-Pax ferry has developed in accordance with a need of ferry operators to reduce fuel oil consumption(FOC) due to the drastic increase in oil prices recently and strengthening of environmental rules and regulations such as CO2 emission. A twin-skeg type is applied as the hull-form in lieu of an open-shaft type in order to improve propulsion performance. In order to achieve this object, flow control devices are installed to reduce a propeller induced vibration which is a main reason to obstruct the application of twin-skeg type passenger vessels owing to an uncomfortable vibration level. Numerical simulation by using an in-house code and a commercial code (Fluent) has performed to find out an optimum design of the flow control devices and to check an improvement in cavity volume. Model tests in Samsung Ship Model Basin are carried out to evaluate propulsion performance with the developed twin-skeg type hull and a reference hull of open-shaft type. In conclusion, it is shown that the twin-skeg type hull is better than the open-shaft in FOC by around 7% and in cavity volume by 20% as well.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.6
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• pp.2909-2916
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• 2016

Background: Canine malignant lymphoma is classified into B- or T-cell origin, as in the human case. Due to differences in prognosis, a suitable method needs to be developed for lineage identification. Aims: To determine the accuracy of immunophenotypic and molecular information between three methods: immunocytochemistry (ICC), immunohistochemistry (IHC) and heteroduplex polymerase chain reaction for antigen receptor rearrangements (hPARR) in spontaneous canine lymphomas. Materials and Methods: Peripheral blood, fine needle aspiration and tissue biopsies from enlarged peripheral lymph nodes prior to treatment of 28 multicentric lymphoma patients were collected. Cytopathology and histopathology were examined and classified using the updated Kiel and WHO classifications, respectively. Anti-Pax5 and anti-CD3 antibodies as B- and T-cell markers were applied for immunophenotyping by ICC and IHC. Neoplastic lymphocytes from lymph node and white blood cell pellets from peripheral blood were evaluated by hPARR. Results: In this study, low grade B-cell lymphoma accounted for 25% (7/28), high grade B-cell lymphoma for 64.3% (18/28) and high grade T-cell lymphoma for 10.7% (3/28). According to the WHO classification, 50% of all cases were classified as diffuse large B-cell lymphoma. In addition, ICC showed concordant results with IHC; all B-cell lymphomas showed Pax5+/CD3, and all T-cell lymphomas exhibited Pax5-/CD3+. In contrast to hPARR, 12 B-cell lymphomas featured the IgH gene; seven presented the $TCR{\gamma}$ gene; five cases showed both IgH and $TCR{\gamma}$ genes, and one case were indeterminate. Three T-cell lymphomas showed the $TCR{\gamma}$ gene. The percentage agreement between hPARR and ICC/IHC was 60%. Conclusions: Immunophenotyping should not rely on a single method. ICC or IHC with hPARR should be used concurrently for immunophenotypic diagnosis in canine lymphomas.

• Journal of Animal Science and Technology
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• v.64 no.6
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• pp.1132-1143
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• 2022

Insects are a valuable natural source that can produce a variety of bioactive compounds due to their increasing species diversity. CopA3 is an antimicrobial peptide derived from Copris tripartitus (i.e., the dung beetle). It is known to increase the proliferation of colonic epithelial and neuronal stem cells by regulating cell cycle. This research hypothesized that CopA3 can promote the proliferation of porcine muscle satellite cells (MSCs). The effects of CopA3 on porcine MSCs, which are important for muscle growth and regeneration, remain unclear. Here, we investigated the effects of CopA3 on porcine MSCs. According to viability results, we designed four groups: control (without CopA3) and three treatment groups (treated with 5,10, and 25 ㎍/mL of CopA3). At a CopA3 concentration of 5 ㎍/mL and 10 ㎍/mL, the proliferation of MSCs increased more than that observed in the control group. Furthermore, compared to that in the control, CopA3 treatment increased the S phase but decreased the G0/G1 phase ratio. Additionally, early and late apoptotic cells were found to be decreased in the 5 ㎍/mL group. The expressions of the myogenesis-related transcription factor PAX7 and MYOD proteins were significantly upregulated in the 5 ㎍/mL and 10 ㎍/mL groups, whereas the MYOG protein remained undetected in all group. This study suggested that CopA3 promotes muscle cell proliferation by regulating the cell cycle of MSCs and can regulate the activity of MSCs by increasing the expressions of PAX7 and MYOD.