• 통합자연과학논문집
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• 제10권1호
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• pp.43-50
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• 2017

Synthetic resins were combined 1-aza-12-crown-4 macrocyclic ligand with styrene divinylbenzene copolymer having 1%, 2%, 8%, and 16% crosslink by a substitution reaction. These synthetic resins were confirmed by chlorine content, elementary analysis, SEM, surface area, and IR-spectrum. As the results of the effects of pH, crosslink of synthetic resin, and dielectric constant of a solvent on metal ion adsorption for resin adsorbent, the metal ions showed high adsorption at pH 3 or over. Adsorption selectivity for the resin in ethanol solvent was the order of uranium ($UO_2{^{2+}}$) > cobalt ($Co^{2+}$) > dysprosium ($Dy^{3+}$) ion, adsorbability of the metal ion was the crosslink in order of 1%, 2%, 8%, and 16% and it was increased with the lower dielectric constant. In addition, theses metal ions could be separated in the column with 1% crosslink resin by using nitric acid (pH 2.0) as an eluent.

• 대한수학회보
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• 제43권1호
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• pp.179-188
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• 2006

For a given p-valent analytic function g with positive coefficients in the open unit disk $\Delta$, we study a class of functions $f(z) = z^p - \sum\limits{_{n=m}}{^\infty} a_nz^n(a_n{\geq}0)$ satisfying $$\frac 1 {p}{\Re}\;(\frac {z(f*g)'(z)} {(f*g)(z)})\;>\;\alpha\;(0{\leq}\;\alpha\;<\;1;z{\in}{\Delta})$$ Coefficient inequalities, distortion and covering theorems, as well as closure theorems are determined. The results obtained extend several known results as special cases.

• 대한치과기공학회지
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• 제43권3호
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• pp.132-137
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• 2021

Purpose: To study the perception and satisfaction of in-person and online classes for dental technology students. Methods: A total of 420 questionnaires were distributed to dental technology students between June 1 and June 30, 2021. Of these, 225 questionnaires were assessed using frequency analysis, one-way analysis of variance, Pearson's Chi-squared test, and independent t-tests via IBM SPSS Statistics ver. 22.0 (IBM). Results: For theory subjects, satisfaction was higher for online classes than in-person classes (p=0.001). For practical subjects, satisfaction was higher for in-person classes than online classes (p=0.002). Both the learning effect and motivation for learning were higher for in-person classes than online classes (p=0.001). Conclusion: When in-person and online classes become coexistent, there should be educational guidelines for improving the quality and effectiveness of learning in these different contexts.

• Clinical and Experimental Reproductive Medicine
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• 제44권2호
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• pp.111-117
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• 2017

Objective: The aim of this study was to evaluate pregnancy outcomes and the live birth rate at 1-year age increments in women aged ${\geq}40years$ undergoing fresh non-donor in vitro fertilization (IVF) and embryo transfer (ET), and to identify predictors of success in these patients. Methods: This retrospective study was performed among women ${\geq}40years$ of age between 2004 and 2011. Of the 2,362 cycles that were conducted, ET was performed in 1,532 (73.1%). Results: The clinical pregnancy rate and live birth rate in women ${\geq}40years$ significantly decreased with each year of increased age (p<0.001). Maternal age (odds ratio [OR], 0.644; 95% confidence interval [CI], 0.540-0.769; p<0.001), basal follicle-stimulating hormone (FSH) levels (OR, 0.950; 95% CI, 0.903-0.999; p=0.047), the number of high-quality embryos (OR, 1.258; 95% CI, 1.005-1.575; p=0.045), and the number of transferred embryos (OR, 1.291; 95% CI, 1.064-1.566; p=0.009) were significant predictors of live birth. A statistically significant increase in live birth rates was seen when ${\geq}3$ embryos were transferred in patients 40 to 41 years of age, whereas poor pregnancy outcomes were seen in patients ${\geq}43years$ of age, regardless of the number of transferred embryos. Moreover, the cumulative live birth rate increased in patients 40 to 42 years of age with repeated IVF cycles, but the follicle-stimulating hormone in those ${\geq}43years$ of age rarely showed an increase. Conclusion: IVF-ET has acceptable outcomes in those < 43 years of age when a patient's own oocytes are used. Maternal age, basal FSH levels, and the number of high-quality embryos and transferred embryos are useful predictors of live birth.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권1호
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• pp.89-97
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• 2020

Purpose: Obese children may often present with advanced bone age. We aimed to evaluate the correlation between factors associated with childhood obesity and advanced bone age. Methods: We enrolled 232 overweight or obese children. Anthropometric and laboratory data, and the degree of nonalcoholic fatty liver disease (NAFLD) were measured. We analyzed factors associated with advanced bone age by measuring the differences between bone and chronological ages. Results: The normal and advanced bone age groups were comprised of 183 (78.9%) and 49 (21.1%) children, respectively. The prevalence of advanced bone age significantly increased as the percentiles of height, weight, waist circumference, and body mass index (BMI) increased. BMI z-score was higher in the advanced bone age group than in the normal bone age group (2.43±0.52 vs. 2.10±0.46; p<0.001). The levels of insulin (27.80±26.13 μU/mL vs. 18.65±12.33 μU/mL; p=0.034) and homeostatic model assessment-insulin resistance (6.56±6.18 vs. 4.43±2.93; p=0.037) were significantly higher, while high density lipoprotein-cholesterol levels were lower (43.88±9.98 mg/dL vs. 48.95±10.50 mg/dL; p=0.005) in the advanced bone age group compared to those in the normal bone age group, respectively. The prevalence of advanced bone age was higher in obese children with metabolic syndrome than in those without (28.2% vs. 14.7%; p=0.016). The prevalence of advanced bone age was higher in obese children with a more severe degree of NAFLD. Conclusion: Advanced bone age is associated with a severe degree of obesity and its complications.

• 한국식품과학회지
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• 제36권2호
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• pp.306-310
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• 2004

본 연구는 왕대나무 줄기의 생리황성 및 기능성을 검토하기 위해서 왕대나무 줄기를 에탄올로 추출하여, 추출물의 항산화 효과와 아질산염 소거능을 측정하였다. 그 결과, 왕대나무 줄기 에탄올 추출물의 전자공여능($RC_{50}$)은 $116.75\;{\mu}g/mL$로 나타났고 SOD 유사활성은 추출물(0.92 mg/mL)을 첨가하였을 때 43.88%로 가장 높게 관찰되었으며, linoleic acid에 대한 항산화력은 추출물($50\;{\mu}g/mL$)을 첨가하여 TBA값을 측정한 결과 배양시간 4일과 6일 경과 후 각각 74.76%, 54.48% 감소율을 보임으로써 효과적인 항산화 효과를 나타내었다. 아질산염 소거능은 추출물(0.2 mg/mL)을 첨가하였을 때 pH 1.2 조건에서 43.02%로 가장 높게 나타났으며 pH가 증가할수록 감소하였다. 이상의 결과를 종합하면 왕대나무 줄기의 에탄올 추출물은 항산화 효과와 아질산염 소거능이 있는 물질을 함유한 것으로 판단된다. 추후, 왕대나무의 항산화 효과와 아질산염 소거능을 나타내는 원인물질에 대한 연구가 진행되어야 할 것이다.

• 한국동물학회지
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• 제26권2호
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• pp.69-81
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• 1983

溫熱處理가 SCK 腫瘍細胞에 미치는 生物學的 環境을 몇가지 측면에서 檢討하였다. 첫째로, 溫熱處理가 in vitro와 in vivo에서 어떤 차이가 있는 지를 알아보기 위해서 生殘曲線을 구하여 비교하여 본 바, in vivo의 경우에 더욱 큰 腫瘍細胞 致死效果를 보았다. 둘째로, 이러한 細胞致死作用의 차이가 나타나는 原因을 알아보기 위해서 溫熱處理가 腫瘍組織과 筋肉組織의 溫度와 pH에 어떤 차이를 나타내는 지를 측정하여 본바, 腫瘍의 경우 溫度는 筋肉보다 높아졌으며, pH는 초기의 上昇을 제외하고는 계속해서 낮은 狀態를 유지했다. 이와 같은 腫瘍내의 酸性狀態가 溫熱處理의 細胞致死效果를 增强시키는 것으로 보였다. 셋째로, 이와같은 腫瘍내 pH의 酸性化의 原因을 규명해 보기 위해서 腫瘍과 肝 속의 乳酸含量을 정량하여 본 바, 腫瘍의 경우 溫熱處理 후 1시간에는 增加하였으나 그 후에는 계속 減少된 상태를 유지했다. 이에 반해서 肝의 경우 5시간에 最大値를 보였고 24시간 동안 계속해서 上昇된 값을 유지했다. 이러한 腫瘍내 乳酸含量의 減少는 예기치 못했던 결과였는데, 이는 溫熱處理로 말미암아 腫瘍내의 細胞가 계속해서 死滅되는 결과로 腫瘍 단위 重量당 乳酸量의 감소를 가져오는 것으로 풀이할 수 있었다. 넷째로, 溫熱處理에 의한 細胞致死效果의 표적을 찾아 보기 위한 한가지 試圖로서 膜表面蛋白質의 變化를 관찰하였던 바, 高分子蛋白質의 減少와 더불어 低分子蛋白質의 增加라는 一般的인 現象을 볼 수 있었고, 특히 70K 단백질이 特異的 增加를 보인 것과 이의 증가가 $41^\\circC$에서 最大의 값을 보인 것은 興味로운 일이었다. 溫熱處理가 腫瘍내 pH의 酸性化를 招來하는 原因과 膜表面蛋白質에 特異한 影響을 미치는 機作에 대해서는 앞으로 더욱 많은 硏究가 傾注되어야 할 興味있는 問題로 생각된다.

• 한국보건간호학회지
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• 제26권3호
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• pp.453-464
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• 2012

Purpose: The purpose of this study was to provide the basic data for university students to develop program for achieving successful developmental task. Method: The subjects involved this study were 462 1-4th grade university students located at Kangwon-Do & Chungchung-Do. Data were measured using Global assessment of recent stress scale, CES-D and Self-esteem scale. Data were analyzed using SPSS WIN 17.0 program that included mean, standard deviation, ANOVA, Sheffe test and Pearson correlation coefficients. Results: 1) The mean score of the degree of perceived stress was 4.17(${\pm}1.43$), depression was .92(${\pm}.47$), and self esteem was 2.89(${\pm}.48$). 2) There were significant differences in the degree of stress according to gender(t=2.03, p=.043), level of living(F=3.55, p=.029). Likewise, there were significant differences in the degree of depression according to gender(t=3.35, p=.001), age(t=2.15, p=.032), level of living(F=3.38, p=.035) and in the degree of self-esteem there were significant difference according to gender(t=3.64, p<.001), age(t=2.81, p=.005), participation of regular meeting or not(t=3.14, p=.002), frequency of alcohol drinking(F=5.59, p=.004), onset age of alcohol drinking(t=2.43, p=.016). 4) There was a significant relationship between stress and depression(r=.556, p<.001), self-esteem (r=-.423, p<.001). Also, there was a significant relationship between depression and self esteem(r=-.667, p<.001). Conclusions: Nursing interventions and educational programs which can help the students to accomplish the developmental tasks required.

• 한국산학기술학회논문지
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• 제20권11호
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• pp.76-84
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• 2019

본 연구는 간호대학생의 도덕적 자아개념, 윤리적 가치관, 연명치료중단 태도 정도를 확인하고 연명치료중단 태도에 미치는 영향을 파악하기 위한 서술적 조사연구이다. 연구대상은 G시에 위치한 2개 대학 간호학과 학생 296명으로, 자료수집을 위한 설문조사는 2017년 6월 12일부터 6월 23일까지 실시하였다. 수집된 자료는 SPSS 23.0 프로그램을 이용하여 분석하였다. 간호대학생의 도덕적 자아개념은 3.48±0.33점, 윤리적 가치관은 3.50±0.37점, 연명치료중단 태도는 3.13±0.43점이었다. 대상자의 일반적 특성에 따른 연명치료중단 태도는 학년(F=3.21, p=.024), 임상실습(t=2.06, p=.040), 간호윤리교육(t=2.98, p=.003)에 따라 유의한 차이가 있었다. 연명치료중단 태도는 도덕적 자아개념(r=-.14, p=.017) 및 윤리적 가치관(r=-.42, p<.001)과 유의한 음의 상관관계가 있었다. 간호대학생의 연명치료중단 태도에 영향을 미치는 요인은 윤리적 가치관(β=-.43, p=<.001), 간호윤리교육(β=.14, p=.010) 순이었으며 이들 예측요인들의 설명력은 22.5%로 나타났다(F=42.09, p<.001). 본 연구결과를 바탕으로 간호대학생의 연명치료중단 태도에 영향을 미치는 다양한 요인을 확인하기 위한 반복연구와 연명치료중단에 대한 긍정적 태도 형성을 위해 공리주의적 가치관을 함양할 수 있는 체계적인 교육 프로그램 개발이 요구된다.

• BMB Reports
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• 제43권7호
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• pp.468-473
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• 2010

Previously, various inhibitors of cell wall synthesis induced the drp35 gene of Staphylococcus aureus efficiently. To determine whether drp35 could be exploited in antistaphylococcal drug discovery, we cloned the promoter of drp35 ($P_d$) and developed different biological assay systems using an engineered S. aureus strain that harbors a chromosomally-integrated $P_d$ - lacZ transcriptional fusion. An agarose-based assay showed that $P_d$ is induced not only by the cell wall-affecting antibiotics but also by rifampicin and ciprofloxacin. In contrast, a liquid medium-based assay revealed the induction of $P_d$ specifically by the cell wall-affecting antibiotics. Induction of $P_d$ by sublethal concentrations of cell wall-affecting antibiotics was even assessable in a microtiter plate assay format, indicating that this assay system could be potentially used for high-throughput screening of new cell wall-inhibiting compounds.