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Crystal Structure of Nalidixic Acid (Nalidixic Acid의 결정구조)

  • 김문집;신준철
    • Korean Journal of Crystallography
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    • v.6 no.2
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    • pp.98-102
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    • 1995
  • The crystal structure of -Ethyl-1,4-dihydro-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid [Nalicixic Acid] has been determined from single crystal X-ray diffraction study; C12H12N2O3, monoclinic, P21/c, a=8.910(2)Å, b=13.145(3)Å, c=9.370(3)Å, β =100.06(2)°, V=1080.6Å, T=293K, Z=4, CuKα(λ=1.5418Å). The molecular structure was solved by direct method and refined by full-matrix least squares to a final R=0.055 for 1555 unique observed [F0>4σ(F0)] reflections and 166 parameters. The conformation of the molecule is stabilized by an intramolecular O(17)-H(17)…O(14) hydrogen bond [2.525(2)Å, 144.3(10)°].

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Optimization and Development of Prediction Model on the Removal Condition of Livestock Wastewater using a Response Surface Method in the Photo-Fenton Oxidation Process (Photo-Fenton 산화공정에서 반응표면분석법을 이용한 축산폐수의 COD 처리조건 최적화 및 예측식 수립)

  • Cho, Il-Hyoung;Chang, Soon-Woong;Lee, Si-Jin
    • Journal of Korean Society of Environmental Engineers
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    • v.30 no.6
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    • pp.642-652
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    • 2008
  • The aim of our research was to apply experimental design methodology in the optimization condition of Photo-Fenton oxidation of the residual livestock wastewater after the coagulation process. The reactions of Photo-Fenton oxidation were mathematically described as a function of parameters amount of Fe(II)($x_1$), $H_2O_2(x_2)$ and pH($x_3$) being modeled by the use of the Box-Behnken method, which was used for fitting 2nd order response surface models and was alternative to central composite designs. The application of RSM using the Box-Behnken method yielded the following regression equation, which is an empirical relationship between the removal(%) of livestock wastewater and test variables in coded unit: Y = 79.3 + 15.61x$_1$ - 7.31x$_2$ - 4.26x$_3$ - 18x$_1{^2}$ - 10x$_2{^2}$ - 11.9x$_3{^2}$ + 2.49x$_1$x$_2$ - 4.4x$_2$x$_3$ - 1.65x$_1$x$_3$. The model predicted also agreed with the experimentally observed result(R$^2$ = 0.96) The results show that the response of treatment removal(%) in Photo-Fenton oxidation of livestock wastewater were significantly affected by the synergistic effect of linear terms(Fe(II)($x_1$), $H_2O_2(x_2)$, pH(x$_3$)), whereas Fe(II) $\times$ Fe(II)(x$_1{^2}$), $H_2O_2$ $\times$ $H_2O_2$(x$_2{^2}$) and pH $\times$ pH(x$_3{^2}$) on the quadratic terms were significantly affected by the antagonistic effect. $H_2O_2$ $\times$ pH(x$_2$x$_3$) had also a antagonistic effect in the cross-product term. The estimated ridge of the expected maximum response and optimal conditions for Y using canonical analysis were 84 $\pm$ 0.95% and (Fe(II)(X$_1$) = 0.0146 mM, $H_2O_2$(X$_2$) = 0.0867 mM and pH(X$_3$) = 4.704, respectively. The optimal ratio of Fe/H$_2O_2$ was also 0.17 at the pH 4.7.

Effects of Process Conditions on the Color and Firmness of Salted Radish Root (Danmooji) at Model System (모델 시스템을 이용한 제조 조건이 단무지의 색도 및 경도에 미치는 영향)

  • Ku, Kyung-Hyung;Park, Wan-Soo;Lee, Kyung-A
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.9
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    • pp.1477-1484
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    • 2005
  • The effects of various seasoning components, pH of seasoning solution, heating time and storage temperature were investigated on the color and textural properties of the salted radish root (nanmooji) The effects of individual seasoning components in the salted radish root, additives of polyphosphate (AD3), citric acid (AD5), malic acid (AD2) delayed the color changes and softening more, compared to control soaked in water. On the other hand, additives of potassium sorbate (AD1), succinic acid (AD7), MSG (AD8), saccharin (AD6) accelerated the color changes and softening of the salted radish roots. The effects of pH of seasoning solution($X_1$), and heating time ($X_2$) were central composite design and response surface analysis. R- square represented dependent variables correlated independent variables ($X_1,\;X_2$), showed over 0.8 in the color and area value calculated thickness and firmness of salted radish root. Especially, R- square of 'b' represented 'yellow-green' was 0.899. And the result of crossing analysis of individual independent variables ($X_1,\;X_2$), showed that both independent variables had significant effects on the color and textural changes of the salted radish root. The salted radish root increased its color changes and softening, rapidly at $40^{\circ}C$, compared to the other storage temperatures at most storage periods.

Evaluation on Motion Features of the World's Second Archer during Back-Tension in Archery (양궁 백 텐션 국면에서 최우수 양궁선수의 동작특성 평가)

  • Yi, Jae-Hun;Hah, Chong-Ku;Ryu, Ji-Seon;Kim, Ki-Chan
    • Korean Journal of Applied Biomechanics
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    • v.17 no.3
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    • pp.197-207
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    • 2007
  • It has been reported that Back-Tension played a significant role in archery (Lee & Bondit, 2005; Kim, 2007) but there are a few researches related Back-Tension in Korea recently. Therefore, the purpose of this study was to investigate archery back tension technique for the second ranked archer in the World and to find ways to improve performance. A subject(height: 185cm, mass: 82kg, years: 21yrs, careers: 12yrs) who is a number of national team and the second ranked archer in the World authorized by FITA (Federation Internationale de Trial Arc) was perticipated in this experiment. When shooting 60 shots($12{\times}5$), shooting motions were recorded with 7 infrared cameras and 2 ultrahigh-speed cameras. A QTM and an Auto Track were used to acquire raw data. The sampling rates of both cameras were 200 Hz. and 1000 Hz. respectively and data were filtered using a fourth order Butterworth low pass filtering with a cutoff-frequency of 30Hz. The parameters were calculated with Matlab6.5 and analyzed with SPSS11.0. After Pearson's correlations between 8 parameters were analyzed, 5 parameters from 13parameters that affected records were analyzed with multiple regression analysis (Enter order: x1, x2, x3, x4, x5). The results were as follows: 1. Comparing between parameters according to scores, the patterns of horizontal and vertical angular velocity(av.) of scapular relative angle was different between 8 score and 9 or 10 scores. 2. The correlations of parameters that affected records were a horizontal av.(x1, p=.032<.05) and a vertical av.(x3, p=.033<.05) of scapular from release to delivery in KB back-tension (anchoring-delivery). 3. The decision coefficients(R2) of above two parameters and three parameters selected by experts that may affect record, that is, an absolute trunk angle(x4) from in KKC back-tension (anchoring-release) and a horizontal relative scapular angle(x2) and an absolute trunk angle(x5) from release to delivery in KB back-tension were 7.7%(x1), 0.1%(x2), 8.5%(x3), 0.7%(x4) and 0.9%(x5) in sequence. 4. The multiple regression equation was a y= -1.16E-2 x1 + 0.109 x2 + 3.437E-2 x3 + 6.139E-2 x4 + 0.117 x5 + 3.420 In conclusion, a total contribution was low, that is, R2(17.9%) suggested that on the one hand, Lim's motion may not depend on a certain factor because his postural factors affected shooting motion are some stable on the other hand, unknown factors may exist(e.g. psychological, physiological factors etc.). Further study of EMG patterns of muscles and anatomic consideration related to shoulder girdle and scapular bones may help to identify mechanism of Back-Tension.

OSCILLATION AND ASYMPTOTIC BEHAVIOR FOR DELAY DIFFERENTIAL EQUATIONS

  • Choi, Sung-Kyu;Koo, Nam-Jip;Ryu, Hyun-Sook
    • Journal of applied mathematics & informatics
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    • v.7 no.2
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    • pp.641-652
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    • 2000
  • In this paper we will survey the recent results about oscillation and asymptotic behavior for the linear differential equation with a single delay x'9t)+p(t)x(t-r)=0, $t\geqt_1$.

The Fabrication and Property Evaluation of Poly-crystalline CdTe based Photon Counting X-ray Sensor (다결정 CdTe 기반의 광계수형 X선 센서 제작 및 특성평가)

  • Kang, Sang Sik;Park, Ji Koon
    • Journal of the Korean Society of Radiology
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    • v.9 no.7
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    • pp.439-443
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    • 2015
  • An electrical signals of a conventional radiation medical imaging sensor are obtained by charge integration method. In this study, the polycrystalline cadmium telluride(p-CdTe) film was fabricated by a thermal evaporation method for the photon counting sensor development with excellent resolution in low exposure dose. From the fabricated p-CdTe sensor, the physical properties(SEM, XRD) and the electrical properties(leakage current, x-ray sensitivity, SNR) were evaluated. As a result, the leakage current of below $5nA/cm^2$ and $7{\mu}C/cm^2-R$ of the X-ray sensitivity were showed in below $1V/{\mu}m$. In addition, the signal to noise ratio showed the values of above 5000 at operating voltage.

A Study of Correlation between the Development of the Third Molar and Second Molar as an Aid in Age Determination (제 2대구치 및 제 3대구치 발육에 따른 연령감정에 관한 연구)

  • Jong-Hoon Choi;Chong-Youl Kim
    • Journal of Oral Medicine and Pain
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    • v.16 no.1
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    • pp.121-136
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    • 1991
  • This study was undertaken to obtain the data for age determination following the calcification degree of the second molar, third molar in the point of forensic odontology. The intraoral panoramic radiograph of 1600 male and 1600 female (100 persons each age) ranging from 7 to 2 years of age were studied. The developmental state of the second molar and third molar were divided into 12 stages following the calcification degree and correlations of second molar developmental stage and statistically analyzed. The results were as follows : 1. There was remarkable correlation between the development of the second molar, the third molar and age. 2. There was no significant developmental differences between the right and left second molar, third molar.(p>0.05) 3. The developmental stages of the lower second molar was more advanced than those of upper second molar. (p<0.05) 4. The developmental stages of upper third molar was more advanced than those of lower third molar. (p<0.05) 5. Both the developmental stages of second, third molars were earlier in the female than in the male. (p<0.001) 6. For the purpose of age estimation according to developmental stages of the second, third molar, linear equations are as follows. (p<0.001) second molar : male upper : Y=1.3927X + 0.2213 (r=0.72) lower : Y=1.4132X + 0.0012 (r=0.78) female upper : Y=1.4914X + 0.2151 (r=0.73) lower : Y=1.5429X - 0.0911 (r=0.78)

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An Experimental Study on the Sanitary Conditions of Eggs (계란의 식품위행학적 조사연구)

  • 이용욱
    • Journal of Environmental Health Sciences
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    • v.1 no.1
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    • pp.9-13
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    • 1974
  • For the purpose of determining the degree of freshness and bacterial contamiation of poultry farm eggs, the author collected 550 specimens from poultry farm, during the period from July 22 through October 3, 1973. Eggs of poultry farm were stored at $4{\pm} 1{\circ}$(Relative humidity 67~86%), $18\pm 1\circ$(70~80%) and $25\pm 1\circ$(73~82%) during 20 days. The results are summarized as follows: 1) Egg weight was decreased $0.97\pm 0.27$ gm at $4\pm 1\circ$, $1.68\pm 0.25$ gm at $18\pm 1\circ$ and $2.76\pm 0.30$ gm at $25\pm 1\circ$ after 20 days. 2) Specific gravity of fresh eggs was found to average 1.0785. 3) Yolk index of fresh eggs was found to average 0.419. 4) The regression equation between Yolk index and days was obtained y=0.417-0.001x (r=-0.481, p<0.05) at $4\pm 1\circ$, y=0.394-0.004 x (r=-0.738, p<0.01) at $18\pm 1\circ$ and y=0.391-0.011 x (r=-0.958, p<0.001) at $25\pm 1\circ$. 5) The regression equation between Yolk index and NaCl concentration (specific gravity) was obtained y=-0.001+0.04 x (r=0.796, p<0.001). 6) pH of albumin was changed from 8.0 to 8.8, 9.2 and 9.3 at $4\pm 1\circ$, $18\pm 1\circ$ and $25\pm 1\circ$ after 20 days. 7) Total Viable Bacteria in air cell was increased slowly according to the stored period at each temperature.

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Crystal structure of 1-tert-butoxycarbonyl-4-[N-(tert-butoxycarbonyl)-N-(ethoxycarbonylmethyl)amino]-3-phenylsulfonylpyrrolidind (1-tert-butoxycarbonyl-4-[N-(tert-butoxycarbonyl)-N-(ethoxycarbonylmethyl)amino]-3-phenylsulfonylpyrrolidind의 결정구조해석)

  • 조소라;김문집
    • Korean Journal of Crystallography
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    • v.6 no.1
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    • pp.27-35
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    • 1995
  • The crystal structure of 1-tert-butoxycarbonyl-4-[N-(tert-butoxycarbonyl)-N-(ethoxycarbonylmethyl)amino]-3-phenylsulfonylpyrrolidind [C24H36O8N2S] has been from single crystal x-ray diffraction study ; C24H36O8N2S triclinic, p1, a=11.363(8)Å, b=11.589(6)Å, c=11.013(10)Å,α=95.32(6)°,β=98.64(7)°,γ=79.57(5)°,V=1406.8(18)Å3, t=293K, Z=2, CuKα(λ=1.5418Å). The molecular structure was solved by diredt method and refined by full-matrix least squares to a final R=9.78% for 3621 unique observed [F≥4σ(F)] reflections and 703 paramenters.

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Effects of Planting Densities and Maturing Types on Growth and Yield of Soybean in Paddy Field

  • Cho, Jin-Woong;Lee, Jung-Joon;Oh, Young-Jin;Lee, Jae-Dong;Lee, Sang-Bok
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.49 no.2
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    • pp.105-109
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    • 2004
  • Field studies were conducted in the southeastern Korea ($36^{\circ}$N) on a commerce silt loam soil at paddy field. Seed were manually planted on 16 July 2003. Plants were planted with plant densities of 70${\times}$10 cm (row width x plant spacing), 50 x 10 cm, and 30 ${\times}$10 cm. Two seedlings per hill were taken prior to V3 stage. Fertilizer was applied prior to plant at a rate of 30-30-34 kg (N-$\textrm{P}_2\textrm{O}_5$-$\textrm{K}_2\textrm{O}$) per ha. Experimental design was a randomized complete block in a split plot arrangement with three replications. Yield from different planting densities responded similarly in three soybean cultivars and increased when planting density increased. Somyeongkong showed the highest increasing rate of yield about 26% by 338 g $\textrm{m}^{-2}$ at 30 x l0 cm compared to yield of conventional planting density (70 x 10 cm). Also, the planting density significantly affected pod and seed number and seed weight, but not seed per pod. The tallest plant appeared at 30${\times}$10 cm. The change of leaf area according to days after emergence showed differently in soybean cultivars. The highest and lowest total dry matter production per square meter appeared at 30 x 10 cm and at 70 x 10 cm, respectively. Crop growth rate (CGR) showed greater at R3∼R4 stages compared with V7∼R2 or R2∼R3 growth stages and showed the greatest at 30 x 10 cm in three soybean cultivars. As late planted soybean, there was a significant relation between seed yield and CGR, and leaf area index (LAI) according to planting densities at before and after the flowering stage. Relationship between seed yield and CGR in three planting densities showed a highly significant positive relation ($\textrm{R}^2$=0.757) at R3 to R4 stages, and significant relations ($\textrm{R}^2$=0.505, 0.617) at V7 to R2 and V2 to V3. Also, there was a highly significant positive difference between seed yield and LAI during R3 to R4 and R2 to R3 stages.