• 제목/요약/키워드: P2X7r

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일상적 생활 스트레스에 대한 아동의 대처행동 척도 개발 (Development of Daily Hassles Coping Scale for Children)

  • 민하영
    • 대한가정학회지
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    • 제36권7호
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    • pp.83-96
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    • 1998
  • The purpose of this study was the development of a scale to assess daily hassles coping behaviors for school aged children. The subjects were 398 children consisted of 197 3rd grade an 201 6th grade. They were selected from elementary school in Seoul, InCheon, DaeJeon, GwangJu and Pusan(202 males and 196 females) A questionnaire as the methodological instrument composed of 65-item daily hassles coping scale, demographic questions, 27-item Children's Depression Inventory and 20-item Locus of Control Scale. Statistics such as mean, %, X2, Cramer's V, Cronbach's α, factor analysis and Person's γ was used for used data analysis. The major findings of this study were as follows; 1)55 items of the 65-item scale were selected through item discriminant method. The discriminant coeffcients of the items(Cramer's V) ranged from .35 to .68. 2)5 factors were extracted from the 1st and the 2nd factor analysis. The subscales labelled 'active' 'passive' 'aggressive' 'avoidant' and 'social support seeking' coping. The criterion validity of this scale was assessed by computing the correlation measures of Children's Depression Inventory and Locus of Control Scale with this scale. Most coefficients were significant(ranging from r=-.16 to r=.40,p<.01,p<.001), although their correlations were modest. 3)Finally, the internal consistency of this scale appeared to be at an acceptable level(Cronbach's α=.90)

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생체 임피던스 방법과 이중 방사선 흡수법으로 측정한 체지방량과 인슐린감수성 지표와의 연관성 (Relationship between the Body Fat Mass Measured by Bioelectrical Impedance Analysis(BIA) and Dual Energy X-ray Absorptiometry(DEXA), and by the Indices of Insulin Sensitivity)

  • 임인석;윤기욱
    • Clinical and Experimental Pediatrics
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    • 제48권8호
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    • pp.857-864
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    • 2005
  • 목 적 : 인슐린 감수성 지표들은 신체계측지수인 체질량지수 및 비만도와 상관관계를 보이는 것으로 알려져 있다. 그러나 이러한 신체계측지수들이 체지방량을 잘 반영하는 것으로 알려져 있기는 하나 소아에서는 성인에 비해 그 정확도가 떨어지므로 실제로 측정한 체지방량과 인슐린 감수성 지표들 간에도 이와 같은 연관성이 있는지에 대한 연구는 없는 실정이다. 따라서 본 연구에서는 단순 소아 비만아들을 대상으로 하여, 체지방측정에 있어 비교적 객관적이며 정확한 방법으로 알려진 BIA와 DEXA로 측정한 체지방량과 인슐린 감수성 지표들 간에 어떠한 연관성이 있는지 알아보고 추후 외래에서 비만아들을 추적 관찰할 때 어느 지표가 가장 유용한지 알아보고자 한다. 방 법 : 2002년 1월부터 2004년 7월까지 중앙대학교 용산병원 비만클리닉을 방문한 28명의 단순비만 환자를 대상으로 하였다. 12시간 이상 금식 후 채혈을 하여 혈당과 인슐린 수치를 측정하였다. 같은 날 신장, 체중, 허리 둘레, 엉덩이 둘레를 계측하였고, BIA와 DEXA를 시행하여 체지방량을 구하였다. 얻어진 혈당과 인슐린 수치를 이용하여 G/I ratio, $log_{insulin}$, HOMA-IR, $log_{HOMA-IR}$, QUICKI를 구하여 체지방량과의 연관성을 알아보았다. 결 과 : 1) 인슐린 감수성 지표 중 G/I ratio만 triglyceride와 통계상 연관성이 있는 것으로 나왔다(r=-0.206, P<0.05). 이외의 $log_{insulin}$, HOMA-IR, $log_{HOMA-IR}$, QUICKI는 혈중 지질치와 관련이 없었다. 2) 비만도는 G/I ratio와 -0.209(P<0.05), $log_{insulin}$과 0.196(P<0.05), HOMA-IR과 0.238(P<0.01), $log_{HOMA-IR}$과 0.198(P<0.05), QUICKI와는 -0.224(P<0.05)로 연관성이 있는 것으로 나왔고, 체질량지수는 G/I ratio와 -0.463(P<0.01), $log_{insulin}$과 0.417(P<0.05), HOMA-IR과 0.301(P<0.01), $log_{HOMA-IR}$과 0.403(P<0.01), QUICKI와는 -0.451(P<0.01)로 나와 비만도 보다 더 인슐린 감수성 지표들과 상관성이 높은 것으로 나타났다. 3) BIA로 측정한 체지방량과 비만도 및 체질량지수 각각에 대한 상관계수는 0.612(P<0.01), 0.316(P<0.05)으로 나왔고, DEXA로 측정한 체지방량과는 각각 0.667(P<0.01), 0.512(P<0.05)로 나와 체지방량과 비만도 및 체질량지수 사이에 연관성이 있는 것으로 밝혀졌다. 4) G/I ratio는 BIA로 측정한 체지방량 및 체지방률과 각각 상관계수 -0.420(P<0.05), -0.366(P<0.05)으로 상관성을 보이고 있었고, DEXA로 측정한 체지방량 및 체지방률과도 -0.512(P<0.01), -0.449(P<0.01)로 높은 상관성을 보였다. HOMA-IR은 DEXA로 측정한 체지방량과만 상관계수 0.341(P<0.05)로 연관성을 나타냈고, 그밖에 다른 인슐린 감수성 지표들은 체지방량 및 체지방률 모두와 상관성이 없었다. 결 론 : 인슐린 감수성 지표들과 비만도 및 체질량지수와 같은 신체 계측지수들 간의 상관성에서, 인슐린 감수성 지표 특히 G/I ratio가 비만도 및 체질량지수 모두와 높은 상관성을 보였고, 체지방량 및 체지방률과 인슐린 감수성 지표와의 관계에서는 G/I ratio만이 BIA와 DEXA로 측정한 체지방량과 체지방률 모두와 연관성이 있는 것으로 나타났다. 따라서 단순 비만아의 진단 및 추적 관찰시 BMI 및 인슐린과 혈당치를 기초로 한 인슐린 감수성 지표 특히, G/I ratio의 활용이 임상에서 유용하게 사용될 수 있을 것으로 생각된다.

Prevalence and risk factors of helminth infections in cattle of Bangladesh

  • Rahman, A.K.M.A.;Begum, N.;Nooruddin, M.;Rahman, Md. Siddiqur;Hossain, M.A.;Song, Hee-Jong
    • 한국동물위생학회지
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    • 제32권3호
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    • pp.265-273
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    • 2009
  • A cross-sectional survey was undertaken to identify risk factors and clinical signs associated with parasitic helminth infections of cattle in Mymensignh district of Bangladesh. A nonrandom convenience sampling method was used to select 138 animals from 40 farmers/herds. The eggs per gram of faeces (epg) for nematodes and trematodes were determined by McMaster and Stoll's methods respectively. Animal-level and herd-level data were recorded by means of a questionnaire. Multi-collinearity amongst explanatory variables were assessed using $2{\times}2{\times}\;X^2$ test and one variable in a pair was dropped if $P{\leq}0.05$ formultiple logistic regression models. Association study between outcome and explanatory variables was conducted using classification tree, random forests and multiple logistic regression. A positive epg was considered as infected. Analyses were performed using $STATA^{(R)}$, version 8.0/Intercooled and $R^{(R)}$, Version 2.3.0. Seventy eight percent of the cattle were found to be infected with at least one type of helminth. Twenty four pairs of combinations of explanatory variables showed significant associations. Male animals (OR=3.3, P=.006, 95% CI=1.4, 7.7) were associated with significantly increased prevalence of nematode infection. Female cattle of the study area are mostly cross-breed, kept indoor, fed relatively good diet and not used for draught purpose. Males are used for draught purpose thereby more exposed to nematode infective stage and provided with relatively poor diet. So stressed male cattle may become more susceptible to nematode infection. All of the three statistical techniques selected gender and lumen motility as most important variables in association with nematode infection in cattle. The result of this survey can only be extrapolated to the periurban cattle population of traditional management system.

간호활동의 유형과 요통 발생에 관한 일 조사연구 (A Survey on Back Pain of Nurses)

  • 한윤복
    • 대한간호학회지
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    • 제7권1호
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    • pp.39-46
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    • 1977
  • Despite the fact that it is not a fatal symptom. the lower back pain of human species is considered a health problem of modern society: 80% of world population experience it and the distress and dysfunction caused by interferes daily life as well as the general productivity. This study was performed to investigate the general tendency of lower back Pain on nurses: influence of nursing activities, working condition and the physical characteristics of nurses on the pain in order to provide data for prevention and treatment. 386 nurses working at 16 general hospitals throughout the country were sampled. Questionaries developed by the researcher was used for data gathering. Results are as follows : 1. Lower back pain was experienced by most(72.3%) of the nurses: the highest rate of -Pain experience was revealed to be the a9e group of 35-39 (80.8%) followed by 25-29 group (74.2%). 2. In almost all instances (91.4%), the first pain attack occurred before the age of 29, and in 73.1%. the attack occurred between the age of 15-24. 3. In 10.1%, the pain was almost persistent or occurred every other day frequency. In 9%, the pain was relieved by the administration of analgesics or "unable to move". 4. More than 6 days′sick leave due to the pain revealed to be in 2.2%. No significant difference was revealed between specialities of service. 5. Pain experience and the over or under weight revealed not to have significant relations. (X$^2$=0.55224, p〉0.7587) 6. The length of working hour of I. C. U. and O. R, revealed to be longer than that of nurses general ward, however. no significant difference on the rate of pain occurrence apparent. (X$^2$=0.4952, p〉0.8239) No significant difference on the rate of pain occurrence between nurses working over 46 hours/week and under 45 hours/week. (X$^2$=3.86241, p〉0.078318) 7. The most frequent Pain related movement revealed to be "lifting patient or heavy object" (24. 7%, N=68) followed by "the sameness of position, either standing or sitting"(16.8%) 8. Regular physical exercise revealed to have no significant influence on the rate of Pain occurrence. 9. Higher raft of pain experience was revealed in the group of nurses wearing eye glasses. Uncomfortable shoes revealed to have influenced the pain. 10. The most frequent pain relieving treatment revealed to be "rest" (54.2%, N= 151) followed by "analgesics" (12.6%, N=35) and "hot compress/fomentation"(10.5%, N=29). In 13.7% (N=38) no special care was given.

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용융염법을 이용한 저차원 구조의 금속 칼코겐 화합물의 합성 및 구조 특성연구 (Synthesis and Characterization of Low-Dimensional Chalcogenide Compound via a Molten Salt Method)

  • 최덕수;윤혜식;오화숙;김돈;윤호섭;박윤봉
    • 대한화학회지
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    • 제48권5호
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    • pp.504-509
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    • 2004
  • 구리 금속 분말과 혼합 알칼리금속 다셀레늄화물 용융염 ($KNaSe_x$) 과의 반응을 통하여 판상형태의 결정을 갖는 $KCu_4Se_3$ 화합물을 얻었다. $KCu_4Se_3$화합물의 구조는 X-선 단결정 회절법에의해 결정되었으며 사반면상을 갖는다. (P4/mmm, a=4.013(1)${\AA}$, c=9.712(1)${\AA}$, z=1, R=6.7%). 그 구조는 안티 PbO 구조를 갖는 $Cu_2Se_2$ 층이 겹쳐짐으로서 만들어지는 $[Cu_4Se_3]_n^{n-}$의 이중층으로 구성되어있다. $KCu_4Se_3$의 단결정에 대한 온도 변화에 따른 저항 측정을 통하여 전도체의 특성을 확인하였으며 300 K에서 $1.8{\times}10^{-4}{\Omega}{\cdot}cm$과 20 K에서 $1.0{\times}10^{-6}{\Omega}{\cdot}cm$의 저항 값을 갖는다.

Bis(ethylenediamine) cuprate(II)$\cdot$Dichromate의 합성 및 결정구조 연구 (Synthesis and Structure of Bis(ethylenediamine) cuprate(II)$\cdot$Dichromate)

  • 김승빈;남궁해
    • 한국결정학회지
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    • 제16권1호
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    • pp.38-42
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    • 2005
  • Bis(ethylenediamine) cuprate(II)$\cdot$dichromate $Cu(C_2H_8N_2)_2{\cdot}Cr_2O_7$의 결정구조는 a=5.682(1), b=8.567(2), c=14.839(3) ${\AA},\;{\alpha}=97.50(2),\;{\beta}=101.06(1),\;{\gamma}=109.38(2)^{\circ}$, 삼사정계(Triclinic), 공간군 P-1, 공간군 번호 2이며, Z=2, V=653.9(2) ${\AA}^3,\;D_c=2.030gcm^{-3},\;{\mu}=3.273mm^{-1}$이었다. 구조분석은 중금속법으로 풀었으며, 최소 자승법으로 정밀화하였고, 최종 신뢰도 값들은 2291개의 회절반점에 대하여 $R_1=0.0256,\;R_w=0.0708,\;R_{all}=0.0316,\;S=1.151$이었다. 구리 착이온의 Cu-N의 평균 거리가 2.010(3) $\AA$이고, 면에 거의 수직으로 Cu-O 평균거리가 2.525(2) $\AA$로써 찌그러진 팔면체 구조를 하고 있다. 두 가지 이온들은 [111]-방향을 따라서 사슬구조를 형성하고, 이 축을 포함한 이차원 (0-11)면상에 놓인 인접한 축들 사이에는 N1-O5와 N3-O1 수소결합으로 연결되어 있다.

INFLUENCE OF DIETARY PROTEIN ON THE APPARENT ABSORPTION AND RETENTION OF SELENIUM IN SHEEP

  • Serra, A.B.;Serra, S.D.;Fujihara, T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제9권5호
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    • pp.551-556
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    • 1996
  • Selenium (Se) apparent absorption and retention in sheep as influenced by diets differing in protein content through soybean meal supplementation was studied. A $3{\times}3$ Latin square design was used with three Japanese Corriedale wethers (45 kg average body weight), three periods, and three dietary treatments. In each period, 7 d dietary adjustment was followed by 5 d total collection of urine and feces. The three dietary treatments were : Diet 1, without soybean meal supplementation (14% crude protein, CP); Diet 2, with 10% soybean meal supplementation (16.5% CP); and Diet 3, with 20% soybean meal supplementation (19% CP). All the diets had a Se supplementation in the form of sodium selenite at 0.2 mg Se/kg dietary DM. The dietary DM intake of the animals was 2% of their body weight. No significant differences were obtained among the three dietary treatments of the Se balance of the animals. However, as percent of Se intake, only urinary Se concentration of Diet 3 was markedly lower (p < 0.05) than the other diets. Fecal Se as percent of Se intake followed the trend of Diet 3> Diet 2 > Diet 1 resulting a Se absorbed as percent of Se intake of 58.9%, 62.3% and 68.2% for Diets 3, 2 and 1, respectively but their differences among each other were insignificant. No significant differences that were observed either on Se retained as percent of intake (Diet 1, 48.2%; Diet 2, 45.2%; Diet 3, 46.0%) or Se retained as percent of Se absorbed (Diet 1, 70.7%; Diet 2, 72.4%; Diet 3, 77.9%). Significant correlation coefficients among the various measures of Se utilization were also observed. Regression analysis showed the following equation: Y = 93.8 - 1.86X (p <0.05, $r^{2}=0.48$), where Y is the Se absorbed as percent of Se intake (%) and X is the dietary protein content (%). This study concludes that Se requirement in sheep is greater when dietary protein content is high.

지반 탁월주기와 지반 운동특성에 관한 연구 (A Study on Predominant Periods and Attenuation Characteristics of Ground Motion)

  • 김소구;차정식;정형식
    • 한국지반공학회지:지반
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    • 제11권2호
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    • pp.139-156
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    • 1995
  • 지반진동특성의 지진공학적인 정밀측정의 일환으로 지반진동의 탁월주기와 지반진동의 거리에 따른 감쇠특성을 현장실험을 통하여 조사하였다. 이 조사는 세가지 부분의 실험을 통하여 결과를 얻었다. 첫째, 지반의 탁월주기는 고감도 디지탈 속도지진계-3축성분 속도계를 이용하는 Seismometer와 디지탈 Seismograph를 이용하여 지반과 건물에서 일정한 주기를 가진 연속적인 미소진동으로 부터 지반 및 건물진동의 탁월주기를 계측하였다. 지반에서의 탁월주기는 0.18~0.23 sec, 건물2층의 탁월주기는 0.26~0.31 sec였다. 둘째, 지반 구조조사는 디지탈 탄성파탐사기를 이용하여 굴절법을 이용한 탄성파탐사를 실시하였다. 실험장소인 한양대학교 안산캠퍼스의 지층구조는 상부층(표토층: surface layer)은 저속도층으로서 662m1s, 하부층(지반층: base ground)은 2210m/s의 P파 속도를 갖고, 주시곡선도로부터 표토층의 두께는 약 7m로 검측되었다. 이것은 7m두깨의 표토층(top soil)과 그 하부에 사질 점토성의 지반층(base ground)이 존재함을 암시한다. 셋째, Seisgun을 이용하여 인공적인 탄성파 에너지원을 만들어 지반의 진동 감쇠특성을 조사 하였다. 거리 감쇠상수(spatial attenuation conf$\ulcorner$icient) Y는 거리에 따른 진폭 을 계산하여 Z-성분(vertical)은 0.0137, X-성분(longitudinal)은 0.0025, Y-성분(transverse)은 0.0290이고 Spatial QP의 값은 각각 5.913~7.575, 32.371 ~41.452, 2.794~3.579의 값이 산출되었었다. 이 결과 다른 두성분에 비해서 종방향(z-성분, longitudinal)성분은 감쇠경향이 낮음을 알 수 있다. 그러므로 이 경우에 구조물 설계시 종방향(x-성분, longitudinal)성분에 대 한 내진설계가 고려 되어야 할 것이다.

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토지피복 특성에 따른 비점오염원 유출특성 평가 (Estimation of Runoff Characteristics of Non-point Pollutant Source by Land Cover Characteristics)

  • 이재운;이윤정;권헌각;윤종수;이춘식;천세억
    • 한국환경과학회지
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    • 제21권8호
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    • pp.977-988
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    • 2012
  • This study analyzed the characteristics of stormwater runoff by rainfall type in orchard areas and transportation areas for 2 years(2010~2011year). Effluents were monitored to calculate the Event Mean Concentrations(EMCs) and runoff loads of each pollutant. The pollutant EMCs by volume of stormwater runoff showed the ranges of BOD 0.9~13.6 mg/L, COD 13.7~45.2 mg/L, SS 4.1~236.4 mg/L, T-N 2.123~21.111 mg/L, T-P 0.495~2.214 mg/L in the orchard areas, and was calculated as BOD 2.3~22.5mg/L, COD 4.4~91.1 mg/L, SS 4.3~138.3 mg/L, T-N 0.700~13.500 mg/L, T-P 0.082~1.345 mg/L in the transportation areas. The correlation coefficient of determination in the orchard area was investigated in the order of Total Rainfall(0.81) > Total Runoff(0.76) > Rainfall Intensity(0.56) > Rainfall Duration(0.46) > Antecedent Dry Days(0.27). Also, in the case of the transportation area was investigated in the order of Total Rainfall (0.55) > Total Runoff(0.54) > Rainfall Intensity(0.53) > Rainfall Duration(0.24) > Antecedent Dry Days(0.14). As the result, comparing valuables relating to runoff of non-pollutant source between orchard areas and transportation areas, orchard area($R^2{\geq}0.5$ : X3, X4, X5) was investigated to have more influence of diverse independent valuables compared to the transportation area($R^2{\geq}0.5$ : X3, X4) and the difference of discharge influence factor by the land characteristics appeared apparently.

Genomic Analyses of Toll-like Receptor 4 and 7 Exons of Bos indicus from Temperate Sub-himalayan Region of India

  • Malik, Y.P.S.;Chakravarti, S.;Sharma, K.;Vaid, N.;Rajak, K.K.;Balamurugan, V.;Biswas, S.K.;Mondal, B.;Kataria, R.S.;Singh, R.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제24권7호
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    • pp.1019-1025
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    • 2011
  • Toll-like receptors (TLRs) play an important role in the recognition of invading pathogens and the modulation of innate immune responses in mammals. The TLR4 and TLR7 are well known to recognize the bacterial lipopolysaccharide (LPS) and single stranded (ssRNA) ligands, respectively and play important role in host defense against Gram-negative bacteria and ssRNA viruses. In the present study, coding exon fragments of these two TLRs were identified, cloned, sequenced and analyzed in terms of insertion-deletion polymorphism, within bovine TLRs 4 and 7, thereby facilitating future TLR signaling and association studies relevant to bovine innate immunity. Comparative sequence analysis of TLR 4 exons revealed that this gene is more variable, particularly the coding frame (E3P1), while other parts showed percent identity of 95.7% to 100% at nucleotide and amino acid level, respectivley with other Bos indicus and Bos taurus breeds from different parts of the world. In comparison to TLR4, sequence analysis of TLR7 showed more conservation among different B. indicus and B. taurus breeds, except single point mutation at 324 nucleotide position (AAA to AAM) altering a single amino acid at 108 position (K to X). Percent identity of TLR7 sequences (all 3 exons) was between 99.2% to 100% at nucleotide and amino acid level, when compared with available sequence database of B. indicus and B. taurus. Simple Modular Architecture Research Tool (SMART) analysis showed variations in the exon fragments located in the Leucine Rich Repeat (LRR) region, which is responsible for binding with the microbial associated molecular patterns and further, downstream signaling to initiate anti-microbial response. Considering importance of TLR polymorphism in terms of innate immunity, further research is warranted.