• 정보처리학회논문지B
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• 제9B권2호
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• pp.147-154
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• 2002

지능형 에이전트 집단(Intelligent Agent Societies (IAS)을 구축함에 있어서 예상되는 여러 작업 조건과 요구사항에 따라 조정을 설계, 구현하는 것은 매우 중요하며, 조정은 IAS의 효과적인 운영을 위해 필요한 여러 가지 메카니즘들로 구성된다. 하지만 현재 이러한 과정에 도움이 되는 이론적인 지원이 거의 없는 것이 현실이다. 본 연구에서는 효과적이고 실질적인 IAS를 설계하는데 도움이 되는, 실험에 근거한 조정 이론을 개발하는 것을 최종 목표로, 우선 모든 에이전트가 공통된 목표를 공유하면서 전적으로 협력하는 분산문제해결 시스템으로 범위를 설정하고, 조정 이론을 생성하기 위한 기초 분석자료를 제공해 줄 시뮬레이션 모델인 "P-System"을 개발하였다. P-System에서 에이전트출간의 조정은 TE(tweakable entity)라 칭한 23개의 제어 변수에 종속적이며, 조정의 수준은 본 연구의 정의에 따라 수치로 표현된 QMC (Quality Measure of Coordination)라 칭한 종속 변수로 표현된다. 특히 본 연구에서는 P-System의 엄청난 전체 실험공간으로부터 편중되지 않은 서브셋을 선택하는 방법과 적절한 서브셋의 규모를 결정하는 방안에 대해서 연구하였다.대해서 연구하였다.

• 약학회지
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• 제36권1호
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• pp.12-16
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• 1992

A new method for the synthesis of alminoprofen, which is a non-steroidal antiinflammatory agent, was described. Ethyl 2-phenyl-propionate(4) was prepared by Friedel-Crafts reaction of benzene with ethyl ${\alpha}-chloro-{\alpha}(methylthio)acetate(1)$, followed by methylation and desulfurization of the resultant ethyl 2-(methylthio)phenylacetate(2). Ethyl 2-(p-aminophenyl)propionate(6) was obtained by nitration of (4) and successive reduction of ethyl 2-(p-nitrophenyl)propionate(5). Alminoprofen was synthesized by reaction of (6) with methallyl chloride, followed by hydrolysis of the resultant ethyl 2-(p-methylallylaminophenyl)propionate (7).

• 컴퓨터교육학회논문지
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• 제7권6호
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• pp.77-84
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• 2004

본 연구는 웹브라우저의 즐겨찾기를 이용하여 교육정보를 공유하기 위한 에이전트 시스템의 설계와 구현에 관한 내용이다. 즐겨찾기를 효과적으로 공유하고 검색하기 위하여 DAML+OIL의 형태로 설계하였다. 제안된 시스템 구조는 CS기반의 P2P 방식을 이용하였다. 연구에서 제안된 에이전트는 즐겨찾기된 정보를 기초로 문서의 정확성 판단과 우선순위 기법에 의해 사용자에게 검색과정과 결과를 제시한 수 있다. 또한 에이전트가 Semantic Web환경에서 DAML을 통해 보다 지능적으로 교육정보를 공유하고 검색할 수 있는 시스템을 구현하였다.

• 한국지능시스템학회논문지
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• 제15권7호
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• pp.840-845
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• 2005

사용자 성향을 학습하는 기존의 지능형 에이전트는 사용자의 정보가 일정 수준 이상으로 축적되어 있거나 충분한 훈련 시간을 통하여 사용자의 성향을 학습하였다. 이러한 지능형 에이전트를 유비쿼터스 환경에 적용하였을 때, 사용자는 지능형에이전트가 학습까지의 시간을 기다려아 하며, 필요한 서비스를 적절히 지원받지 못하는 경우가 발생할 수 있다. 본 논문에서는 사용자들이 가지고 있는 자원을 공유함으로써 사용자의 성향을 실시간으로 학습할 수 있는 지능형 P2P 모바일 에이전트 시스템을 제안한다. 제안한 시스템은 평가를 위해 4개의 장소에서 사용자들의 컨텍스트를 공유시키고, 유가한 사용자들을 피어그룹으로 설정하였다. 그리고 이 피어 그룹에서 상관계수가 가장 놀은 사용자의 서비스를 제공한 결과, $80\%$이상의 서비스 만족도를 보였다.

• 한국지능시스템학회논문지
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• 제15권5호
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• pp.538-544
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• 2005

유비쿼터스 컴퓨팅 환경에서 사용자를 위한 서비스 지원 구조는 사용자 주변에 공유된 자원을 사용자의 상황에 따라 효율적으로 분배하는 기술이 요구된다. 그러기 위해서는 사용자의 상황 정보에 맞게 제공된 서비스 항목과 자원을 분석하고, 필요한 서비스 및 자원을 적합하게 분배하는 연구가 필요하다. 따라서 본 논문에서는 휴대용 모바일 장치를 이용하여 사용자의 상황을 인식하고, 사용자 상황에 맞도록 서비스된 항목을 공유시킴으로써 지능적인 서비스 지원이 가능한 지능형 P2P 모바일 에이전트 구조를 제안한다. 제안한 구조는 특정 자원에 대한 독점성을 제거하고, 효과적인 사용자 상황 인식 및 서비스 지원을 목적으로 한다.

• 한국초지조사료학회지
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• 제16권4호
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• pp.315-326
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• 1996

An experiment was carried out to determine effect of cultivar, drying agent concentration and preservative on the moisture content, temperature and quality changes of fall harvested oat(Avena sativa L.) hay during field curing and storage. The main plots consisted of the cultivar such as 'Foothill' and 'Swan', the subplots consisted of drying agent concentration such as 7Skg/ha(C1), lOSkglha(C2) and control(C0) and the sub-subplots consisted of preservative such as buffered acid(BA), lactic bacteria inoculant(LB) and control(C0). Moisture contents of 'Foothill' and 'Swan' oat cultivar at harvest were 635.5 and 385.4%DW(Dry weight), respectively, but the final moisture contents of the oat cultivars were 117 and 86%DW. The moisture content of cut oat was not affeded by drying agent concentration. Core temperature of baled 'Swan' oat hay was a little higher than that of 'Foothill' and no consistent preservative effect was found. Total nitrogen content of 'Swan' oat hay was 3.08% and that of 'Foothill' oat hay was 3.45%(P<0.05). Drying agent treatment increased total nitrogen content of 'Swan'(P <0.05), but preservative had no effect. Crude fiber content of oat cultivar was increased as the curing progressed(P<0.05) and the difference of crude fiber content of oat cultivar was maintained through the whole curing period. Effect of drying agent concentration on crude fiber content was not found after preservation. Crude fiber content of 'Swan' oat hay was higher than that of 'Foothill' by 1.O% in ADF and 3.1 % in NDF(P<0.05). No preservative effect was found in crude fiber content. According to RFV of oat cultivar at harvest, forage quality of 'Foothill' and 'Swan' was Prime and Grade 1, respectively, but that of both cultivm was above Grade 2 at the final curing day. RFV of the stored 'Foothill' and 'Swan' oat hay was 122 and 114(P<0.05), respectively, and the quality of oat hay was classified as Grade 1 and 2, respectively, according to the forage quality standard assigned by AFGC.

• 약학회지
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• 제36권4호
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• pp.341-344
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• 1992

A facile method for tolmetin, which is a potent antiinflammatory agent, is described. Friedel-Crafts reaction of 1-methylpyrrole with ethyl ${\alpha}-chloro-{\alpha}-(methylthio)acetate$ (1) gave ethyl ${\alpha}-methylthio$-1-methyl-2-pyrroleacetate (4), which was readily converted into ethyl 1-methyl-2-pyrroleacetate (5) by reductive desulfurization with zinc dust in acetic acid. Tolmetin was synthesized by Friedel-Crafts acylation of (5) with p-toluoyl chloride, followed by hydrolysis of the resultant ethyl 5-(p-toluoyl)-1-methylpyrrole-2-acetate (6).

• 미생물학회지
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• 제20권1호
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• pp.11-20
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• 1982

A study was undertaken to examine the effect of curing agents on the stability, curing and segregation of R plasmid pSL100. And also the stability, transfer frequency, and recombination of its segregants obtained from curing agent treatment were studied. Ethidium bromide, acridine orange, and mitomycin-C were used as curing agent. The results obtained were as follows ; 1. The curing agent ethidium bromide, acridine orange, and mitomycin-C were not effective for curing the multiple antibiotic resistant determinant of pSL100 in Salmonella typhimurium and Escherichia coli. However, they induced plasmid segregation with high frequency in S.typhimuruim LT-2strains. TcApSmCm, TcSmCmKm, TcApCm, TcAp, TcKm, Tc segregants were obtained. 2. The resistant markers of the segregents were transferred to S.typhimurium LT-2 strains with high frequencies whereas they were transferred to E.coli K-12 only with low frequencies. 3. The transconjugants obtained from conjugation between two different S.typhimurium segregants were similar to the phenotype of the original R factor pSL100 and the resistant markers were transferred to the S.typhimurium LT-2 or E.coli strain with equal frequencies, indicating that they are recombinants. 4. The transconjugants obtained from conjugation between pSL100 segrgants and pKM101, or pBR322 possessed the resistant markers of the two parental plasmids and they were transferred to both S.typhimurium and E.coli K-12 strains with the same frequencies and maintained stably, suggesting that they are also recombinants. 5. The recombinant pSL100 could be also obtained in rec A-strains of E.coli, suggesting that the gene function of rec A is required for the recombination of pSL100 segregants in E.coli.

• Journal of Pharmaceutical Investigation
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• 제1권1호
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• pp.101-108
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• 1971

The stability and toxicity test for p.p'-DDT, DDVP and dipterex that put to used sample in this study effects is follows A. about p.p'-DDT (1) In elevating the stability of p.p'-DDT, best stabilizing solvent was benzene. (2) The stability-agent has no difficulty as long as it not contain metal ion for instance $Z_n^{2+}$,$C_r^{3+}$,$Al^{3+}$,and $Fe^{2+or3+}$ but in case of contain $F_e^{3+}$, the combination of salicylaminoguanidine is best effective. (3) Using this product for water-suspension, We must use span 40 for stability agent and adding it at the same time. (4) We must use container which does not week alkali and metal ion but it is to preserved in tight light-resistant container. (5) The stopper of container is adapted with above-mentioned condition of container, but it is better not to use metal material. (6) This product needs opening ventilation more than 30 minutes after diffusion or spray and in the room we remove cause of remained poison by cleaning the bottom. B. about DDVP and Dipterex (1) Benzene or toluene in best solvent to preserve stability of DDVP and Dipterex. (2) Span 40 is superior for stability agent of this product and second is span 80. (3) The pH of solution is very stable in pH 5-6 and comparative stable in alkali more than p,p'-DDT. (4) Container is to preserved in tight, lightresistant container and especially be careful of outflow and inflow of water. (5) Because this product is centeral stimulant poison, we must pay attention to prevent cause of contact diadermic toxicity after use.

• Journal of Microbiology and Biotechnology
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• 제9권6호
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• pp.826-831
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• 1999

${\beta}-Glucan$, one of the major cell wall components of Saccharomyces cerevisiae, is known to enhance the immune function, especially by activating macrophages. Accordingly, in an effort to develop a safe and efficient immune stimulatory agent, we prepared crude ${\beta}-glucan$ (glucan-p1) and partially purified ${\beta}-glucan$ that was free of mannoproteins (glucan-p2), and evaluated their effect on both the macrophage function and resistance to E. coli-induced peritonitis. To investigate the function of the macrophages, phagocytosis, $TNF-{\alpha}$ secretion, oxygen burst, and the expression of cytokine genes such as $IFN-{\gamma}$ and IL-12 were analyzed. Glucan-p2 markedly stimulated the macrophages with all these parameters. Glucan-p1, however, did not stimulate phagocytosis, yet it induced $TNF-{\alpha}$ secretion, oxygen burst, and the expression of $IFN-{\gamma}$ and IL-12, although less efficiently than glucan-p2. Finally, to test the in vivo protective effect of {\beta}-glucan against infection, the survival of mice from E. coli-induced peritonitis was investigated. After 24 h of the peritoneal challenge of E. coli, all of the mice treated with glucan-p2 survived whereas none survived in the control group. Glucan-p1 showed only a marginal effect in protecting the mice. These results suggest that mannoprotein-free gluean-p2, but not gluean-p1, can serve as an effective immune-stimulating agent.