• Title/Summary/Keyword: P2P Agent

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Real-time measurement of dentinal fluid flow during desensitizing agent application (상아질 지각과민 처치제의 적용 중에 일어나는 상아세관액 유동의 실시간 측정)

  • Kim, Sun-Young;Kim, Eun-Joo;Lee, In-Bog
    • Restorative Dentistry and Endodontics
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    • v.35 no.5
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    • pp.313-320
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    • 2010
  • Objectives: The aim of this study was to examine changes in the dentinal fluid flow (DFF) during desensitizing agent application and to compare permeability after application among the agents. Materials and Methods: A Class 5 cavity was prepared to exposure cervical dentin on an extracted human premolar which was connected to a sub-nanoliter fluid flow measuring device (NFMD) under 20 cm water pressure. DFF was measured from before application of desensitizing agent (Seal&Protect, SP; SuperSeal, SS; BisBlock, BB; Gluma desensitizer, GL; Bi-Fluoride 12, BF) through application procedure to 5 min after application. Results: DFF rate after each desensitizing agent application was significantly reduced when compared to initial DFF rate before application (p < 0.05). SP showed a greater reduction in DFF rate than GL and BF did (p < 0.05). SS and BB showed a greater reduction in DFF rate than BF did (p < 0.05). Conclusions: Characteristic DFF aspect of each desensitizing agent was shown in NFMD during the application procedure.

A Study on the Effect of Aftertreating(Antistatic and Softening) Agents in Laundering (시판 세탁후처리제(대전방지 및 유연처리제)의 효과에 관한 연구)

  • Lee Yang Hun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.9 no.2
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    • pp.27-34
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    • 1985
  • Cotton, P/C and polyester fabrics were laundered and treated with 4 kinds of aftertreating agent(antistatic and softening agents) on marketing. Some treating condition:. which include agent concenteration, treating time and rinsing extent after laundering, were varied. And then the effects of agents with each treating condition-handle value, charged voltage and half-life, and crease recovery etc.-were determined and discussed about their change. The improvement of handle and antistatic properties by treatment were indicated remarkably for cotton fabric and P/C and polyester fabrics respectively. Generally, the handle value of cotton was decreased and then increased again, and the charged voltage and half-life of P/C and polyester fabrics were decreased with increase of concenteration of agents. The effect of antistatic improvement for P/C fabric was larger than polyester fabric at even lower concenteration of agents. The effects were increased with treating time and rinsing extent. In particular, those of short time(1 minute) treatment were very small.

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The Cytotoxic Action of New Ag-Porphyrin as a Potential Chemotherapeutic Agent

  • Nelli, Babayan;Artak, Tovmasyan;Ani, Gevorkyan;Gennadi, Gasparyan;Rouben, Aroutiounian
    • Korean Journal of Environmental Biology
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    • v.26 no.2
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    • pp.115-120
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    • 2008
  • Earlier we have described new water-soluble Ag- and Zn-derivatives of tetrachloride meso-tetra (4-N-oxiethylpyridyl) porphyrin (TOEtPyP) as potential anticancer drugs. In this work the effect of one of these metal porphyrins, TOEtPyP Ag, on the cell population kinetics was studied in vitro using morphological and biochemical techniques. The results suggested that TOEtPyP Ag action consisted in the simultaneous suppression of the cell growth and activation of the cell death. About 40% of the cells were shown to die via apoptotic pathway. So, the porphyrin studied may be attributed to inducers of both necrotic and apoptotic processes. The results obtained support our previous assertion that TOEtPyP Ag may be considered as a potential chemotherapeutic agent.

Antigenotoxicity of Galangin and its Action Mechanism (Galangin의 유전독성 억제효과와 작용기전)

  • 허문영;류재천
    • Environmental Mutagens and Carcinogens
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    • v.18 no.2
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    • pp.77-82
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    • 1998
  • In order to compare the suppressive effect of galangin on the genotoxicity by N-methyl-N-nitrosourea (MNU) or benzo[a]pyrene B(a)P, in vivo micronycleus test using mouse peripheral blood and in vitro sister chromatid exchange(SCE) test using mouse spleen lymphocytes were performed. MNU or B(a)P-induced micronucleated reticulocytes in vivo was decreased by the simultaneous treatment of galangin. MNU or B(a)P-induced SCEs in vitro was also decreased by the simultaneous treatment of galangin. On the other hand, the determinations of [$^3$H]MNU-induced total DNA binding and methylated DNA were performed to find out the mechanism of action. [$^3$H]MNU-induced total DNA binding was inhibited by the treatment of galangin in calf thymus DNA. HPLC analysis of DNA hydrolysates showed that galangin caused a decrease of 7-methyl guanine and $O^{6}$-methyl guanine in calf thymus DNA. To elucidate the action mechanism of galangin against B(a)P, alteration of B(a)P metabolism was studied. Galangin inhibited B(a)P metabolism in the presence of S-9 mix and decreased B(a)P-DNA binding in calf thymus DNA with S-9 mix.

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Effect of Plating Condition and Plating Rate on the Magnetic Properties of Electroless Co-Cu-P Deposits (무전해 Co-Cu-P 도금층의 자성에 미치는 도금조건과 도금속도의 영향)

  • Oh, I.S.;Park, S.D.
    • Journal of Power System Engineering
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    • v.8 no.3
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    • pp.36-43
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    • 2004
  • The effect of bath composition, plating condition and plating rate on the magnetic property of electroless Co-Cu-P deposits were investigated. With increasing $CuCl_2$ concentration in the bath, plating rate increased, while the Br value of deposit decreased sharply. Deposited surface were inferiority by the increase pH above 10.5, bath temperature higher than $80^{\circ}C$. Plating reaction had been ceased by the increase of pH above 11, bath temperature higher than $90^{\circ}C$ and under $40^{\circ}C$. The Br value of deposit was uniform with various concentration of complexing agent(sodium citrate) in the bath. The Br value of deposit was almost equal to that found by the addition of stabilizer (thiourea) and accelerator(NaF). The Br value of deposit was uniform in plating time(20min) and heat treatment temperature(below $200^{\circ}C$), and were confirmed to have adequate bath stability for practical use.

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The Effect of Daecheongryong-tang and prescription A on airway mucin secretion (Mucin 분비에 미치는 대청룡탕(大靑龍湯) 및 <석실비록(石室秘錄)> 급치법방(急治法方)에 대한 연구)

  • Park, Wan-Yeol;Suh, Woon-Gyo
    • The Journal of Internal Korean Medicine
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    • v.27 no.1
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    • pp.92-101
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    • 2006
  • Objectives : This study was done with intend to investigate whether two oriental medical prescriptions, daecheongryong-tang (DCRT) and prescription A (P-A) significantly affect mucin release from cultured hamster tracheal surface epithelial (HTSE) cells. Methods : Confluent HTSE cells were metabolically radiolabeled with $^3H$-glucosamine for 24 hrs and chased for 30 min in the presence of DCRT or P-A to assess the effect of each agent on $^3H$-mucin release. Possible cytotoxicities of each agent were assessed by measuring lactate dehydrogenase (LDH) release. Also, the effects of DCRT and P-A on contractility of isolated tracheal smooth muscle were investigated. Results were as follows : 1. DCRT significantly inhibited mucin release from cultured HTSE cells, with significant cytotoxicity. 2. P-A significantly increased mucin release from cultured HTSE cells, with significant cytotoxicity. 3. DCRT inhibited Ach-induced contraction of isolated tracheal smooth muscle. 4. P-A also inhibited Ach-induced contraction of isolated tracheal smooth muscle. Conclusion: Results suggest that DCRT and P-A have regulating effects on mucin secretion from goblet cells. Further investigation is needed, because of the value in finding novel agents to this purpose, and these oriental medical prescriptions have potential for this role.

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Comparison of the hemodynamic effects of propofol and ketamine as anesthetic induction agents during high-dose remifentanil administration: a single-center retrospective comparative study

  • Sanuki, Takuro;Mishima, Gaku;Kurata, Shinji;Watanabe, Toshihiro;Kiriishi, Kensuke;Tachi, Mizuki;Ozaki, Yu;Okayasu, Ichiro;Kawai, Mari;Matsushita, Yuki;Miura, Keiichiro;Ayuse, Takao
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.15 no.3
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    • pp.129-134
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    • 2015
  • Background: We hypothesized that ketamine, when administered as the anesthetic induction agent, may prevent cardiovascular depression during high-dose remifentanil administration, unlike propofol. To test our hypothesis, we retrospectively compared the hemodynamic effects of ketamine, during high-dose remifentanil administration, with those of propofol. Methods: Thirty-eight patients who underwent oral surgery at the Nagasaki University Hospital between April 2014 and June 2015 were included in this study. Anesthesia was induced by the following procedure: First, high-dose remifentanil ($0.3-0.5{\mu}g/kg/min$) was administered 2-3 min before anesthesia induction;next, the anesthetic induction agent, either propofol (Group P) or ketamine (Group K), was administered. Mean arterial pressure (MAP) and the heart rate were recorded by the automated anesthesia recording system at four time points: immediately before the administration of high-dose remifentanil (T1);immediately before the administration of propofol or ketamine (T2);2.5 min (T3), and 5 min (T4) after the administration of the anesthetic induction agent. Results: In Group P, the MAP at T3 ($75.7{\pm}15.5mmHg$, P = 0.0015) and T4 ($68.3{\pm}12.5mmHg$, P < 0.001) were significantly lower than those at T1 ($94.0{\pm}12.4mmHg$). However, the MAP values in the K group were very similar (P = 0.133) at all time points. The heart rates in both Groups P (P = 0.254) and K (P = 0.859) remained unchanged over time. Conclusions: We showed that ketamine, when administered as the anesthetic induction agent during high-dose remifentanil administration, prevents cardiovascular depression.

In Vitro and In Vivo Evaluation of the Combined Products of Antacid and Anti-ulcer Drug (제산제와 항궤양제 복합제제의 In Vitro 및 In Vivo 제산력 평가)

  • Kim, Chong-Kook;Ahn, Hye-Jin;Jeong, Eun-Joo;Oh, Kyung-Hee;Lah, Woon-Lyong
    • Journal of Pharmaceutical Investigation
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    • v.23 no.4
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    • pp.217-223
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    • 1993
  • The combined products of antacid and anti-ulcer agent were prepared with antacid composed of aluminium hydroxide dried gel, magnesium hydroxide and simethicone with a ratio of 1:1:0.1 (M) and anti-ulcer agent, aceglutamide aluminium (AGA). The efficacy of antacid was evaluated in vitro with Fuchs, Johnson-Duncan and Rosset-Rice methods and in vivo using an aspiration method in rat. The addition of anti-ulcer agent did not affect the neutralizing capacity of M significantly. The combined products with the M/AGA ratios of 2.3:1 and 3.4:1 produced the maximum pH of $4.0{\sim}5.8$ and the duration time of $64{\sim}137$ min in vitro test. The in vivo neutralizing test in rats showed the rapid increase of gastric pH up to 3.5 within 30 min and the gastric pH of $4{\sim}6$ was kept for 5 hr.

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Basic Oxygen Furnace Slag as a Liming Agent for Paddy and Upland Field Soils (전로슬래그 시용의 토양개량 및 작물의 수량증대 효과)

  • 이충일
    • Resources Recycling
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    • v.7 no.1
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    • pp.50-56
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    • 1998
  • Basic oxygen furnace @OF) slag. a by-pradud of thc iron and steelmaking industry produced in largc quantities in Korea, poszs a subslantial disposal challenge. The BOF slag used in this study was if3 CaCO, in total n e u ~ ~ pnowger and application of 7-8 Mgha' was needed to bring soil pH to 6.5 horn pH 5.0-5.5 m silly clay or clay loam sod wnlained about 10% orgaoic matter. A field assay was conducted to shldg whether BOP slag could bc used as a dolomitic k i n g agent for agricullural soils. Four slag rates (0, 4, 8, 12 Mgha-')were investigated for their effcfect on soil pmperti~, mineral concentralions in leaf tissues of rice and soybean, and yield of the crops. Slag application at 8 Mgha-' rate in paddy field increased pH, Ca Mg, P, Si and Fe wntenl in sail and rice yield by 4.3-14.25 depending an the soil type. h upland field the 8 Mghaf ratc increa3ed pH, Ca and Fe wntent m soil and soybean yield by 36.6%. Thus, BOF slag appears to be a useful liming mate&\ulcornerl for corrzch~gs oil acidity on both paddy and upland ficld soils and for innwing Ca, Mg, P, Si, and Fe wncenhation in plants.

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Implementation of QoS Agent for Distance video Learing (원격 화상교육을 위한 QoS 에이전트 구현)

  • Kim, Song-Young;Song, Jong-Myung;Shin, Seung-Soo;Choi, Seung-Kwon;Cho, Young-Hwan
    • Proceedings of the Korea Contents Association Conference
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    • 2004.11a
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    • pp.21-25
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    • 2004
  • The proposed QoS Agent System for distance video learning is used unicast and P2P. This method is developed for decreased the traffic of server by control agent. First step capture from stream server's camera, and transmitted streaming data to the first CSplayer(c/s), and outrank CSplayer transmitted streaming data to the subordinate CSplayer controled by QoS Control Agent.

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