Journal of Dental Anesthesia and Pain Medicine
- Volume 15 Issue 3
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- Pages.129-134
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- 2015
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- 2383-9309(pISSN)
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- 2383-9317(eISSN)
DOI QR Code
Comparison of the hemodynamic effects of propofol and ketamine as anesthetic induction agents during high-dose remifentanil administration: a single-center retrospective comparative study
- Sanuki, Takuro (Division of Clinical Physiology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Mishima, Gaku (Division of Clinical Physiology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Kurata, Shinji (Department of Dental Anesthesiology, Nagasaki University Hospital) ;
- Watanabe, Toshihiro (Department of Dental Anesthesiology, Nagasaki University Hospital) ;
- Kiriishi, Kensuke (Department of Dental Anesthesiology, Nagasaki University Hospital) ;
- Tachi, Mizuki (Department of Dental Anesthesiology, Nagasaki University Hospital) ;
- Ozaki, Yu (Division of Clinical Physiology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Okayasu, Ichiro (Division of Clinical Physiology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Kawai, Mari (Division of Clinical Physiology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Matsushita, Yuki (Division of Clinical Oral Oncology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Miura, Keiichiro (Division of Department of Regenerative Oral Surgery, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences) ;
- Ayuse, Takao (Division of Clinical Physiology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences)
- Received : 2015.09.09
- Accepted : 2015.09.24
- Published : 2015.09.30
Abstract
Background: We hypothesized that ketamine, when administered as the anesthetic induction agent, may prevent cardiovascular depression during high-dose remifentanil administration, unlike propofol. To test our hypothesis, we retrospectively compared the hemodynamic effects of ketamine, during high-dose remifentanil administration, with those of propofol. Methods: Thirty-eight patients who underwent oral surgery at the Nagasaki University Hospital between April 2014 and June 2015 were included in this study. Anesthesia was induced by the following procedure: First, high-dose remifentanil (