• Title/Summary/Keyword: P-value

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Assessment of Biochemical Profiles in Premenopausal and Postmenopausal Women with Breast Cancer

  • Yadav, Naval Kishor;Poudel, Bibek;Thanpari, C.;Koner, Bidhan Chandra
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3385-3388
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    • 2012
  • Objective: The study was conducted to assess biochemical profiles in premenopausal and postmenopausal women having breast cancer. Materials and Methods: A hospital based case control study was carried out at Manipal Teaching Hospital (MTH), Pokhara, Nepal. The analysed variables were age, metabolic profile including total cholesterol, triglycerides, HDL-C, LDL-C, blood sugar, insulin concentration, C-peptide, HbA1c and selenium. Descriptive statistics and testing of hypothesis were used for the analysis using EPI INFO and SPSS 16 software. Results: In premenopausal women, significant differences were noted for total cholesterol (P value <0.001), triglycerides (P value 0.002), HbA1c level (P value <0.001), insulin concentration (P value 0.030), C-peptide concentration (P value 0.001), and selenium (P value <0.001) between cases and controls. Insignificant results were found for HDL-C (P value 0.749), LDL-C (P value 0.933), blood sugar (P value 0.59) and BMI (P value 0.746). Similarly, significant difference in total cholesterol (P value <0.001), triglycerides (P value 0.001), LDL-C (P value <0.001), HDL-C (P value 0.025), blood sugar (P value <0.001), insulin concentration (P value <0.001), c-peptide concentration (P value <0.001), HbA1c level (P value <0.001) and selenium (P value <0.001) were observed for postmenopausal patients and controls. Conclusions: Assessing metabolic changes and their management may be important for control of breast cancer and increased survival.

Evaluation of the quality stability on the soybean flour depending on storage conditions

  • Park, Sung-Kyu;Son, Na-Young;Kim, Mi-Jung;Chung, Ill-Min
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.264-264
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    • 2017
  • Legumes are good sources of various nutrients. Among legumes, soybean and its flour are accessible foods to consumers. However, in case of soybean flour, there is a disadvantage of easily going rancid. Thus, this study aimed to investigate how the quality of soybean flour changes during storage according to the packaging materials and storage temperatures. The raw and roasted soybean flours were packed in two types of packaging, polyethylene (PE) and polypropylene (PP) film bags respectively, and stored at three different storage temperatures (4, 20, and $45^{\circ}C$) for 1 year. The acid value, conjugated diene value, peroxide value, p-anisidine value, thiobarbituric acid (TBA) value, lipoxygenase activity, and fatty acid content of raw and roasted soybean flours were measured at the point of starting storing, and after 1, 2, 4, 8, and 12 weeks of storage. The acid value of soybean flour was increased for 4 weeks and thereafter significantly decreased (p < 0.0001). The conjugated diene value was significantly increased after 4 weeks storage at $45^{\circ}C$ with PE and PP film bags (p < 0.0001). The peroxide value had no changes during 4 weeks storage at $45^{\circ}C$ with PE and PP film bags, and then those was dramatically increased after 8 weeks (p < 0.0001). The p-anisidine values in all of storage conditions were decreased after 4 weeks. Lipoxygenase activity was decreased at 12 weeks storage at $20^{\circ}C$ and $45^{\circ}C$ with PP film bags. Acid value had positive correlations with p-anisidine value (r = 0.30 and p < 0.0001) and lipoxygenase activity (r = 0.36 and p < 0.0001), and had negative correlations with conjugated diene value (r = -0.45 and p < 0.0001) and peroxide value (r = -0.25 and p < 0.001). Conjugated diene value had a high positive correlation with peroxide value (r = 0.76 and p < 0.0001), but that had a negative correlation with lipoxygenase activity (r = -0.51 and p < 0.0001). Peroxide value had negative correlations with p-anisidine value (r = -0.20 and p < 0.01) and TBA value (r = -0.15 and p < 0.05). The degree of reduction in fatty acid content of raw soybean flour was higher than the roasted soybean flour during the storage. Total fatty acid content had positive correlations with acid value (r = 0.45 and p < 0.0001) and p-anisidine value (r = 0.58 and p < 0.0001), but had a weak negative correlation with conjugated diene value (r = -0.19 and p < 0.01). This study showed how the rancidity of the raw and roasted soybean flours progressed during storage. Thus, our findings can be used as base data to do a further study of finding and developing more stable storage conditions of the soybean flour.

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X-Ray Diffraction Studies of Uranyl Hydrolysis Precipitates Synthesized in Neutral to Alkaline Aqueous Solutions

  • 박용준;표형렬;김원호;전관식
    • Bulletin of the Korean Chemical Society
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    • v.17 no.10
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    • pp.925-929
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    • 1996
  • Uranyl hydrolysis precipitates were obtained by increasing pH value of aqueous uranyl solution in the range of neutral to alkaline pH value and their phase transformation during the solubility experiment under various conditions has been examined. The precipitates formed in the hydrolysis reaction of uranyl ion had a layered structure such as a meta-schoepite phase, a schoepite structure, or a mixed phase of meta-schoepite and schoepite. Phase transformation between them was strongly dependent on the pH value at which the precipitate was formed. The distance between the layers in meta-schoepite or schoepite phase was ∼7.35 Å, and it was increased with the pH value at which the precipitate was synthesized as well as the pH values of the aqueous solution. The phase transformation from a meta-schoepite to schoepite was fast for the precipitates formed at low pH values, however, it was not the case for the precipitates formed at high pH values. A small difference of pH value in aqueous solution gave a great change on its solubilities near pH 9.7, because a layered structure of the precipitates became amorphous above that pH value. Greater solubility for the precipitate formed at higher pH value can be explained from the fact that the precipitates formed at low pH value had a better crystallinity and also that the precipitates formed at higher pH value has a slower rate of crystallization.

Relationship between Health Promotion Behavior and Marriage Value View

  • Kim, Jungae;Seo, Eunhui
    • International Journal of Advanced Culture Technology
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    • v.8 no.3
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    • pp.10-17
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    • 2020
  • This study was cross sectional descriptive survey study to analysis the relationship between marriage value view and health promotion behavior among university students. Questionnaires from those who voluntary agreed to the study were collected online, and the collection period was from May 20, 2020 to June 10, 2020. Research tools for analyzing marriage value view was used by RR lee, and health promotion behavior research tools was developed by Walker., The data analysis was performed using SPSS 18.0 as frequency, Pearson correlation, t-test, and Multiple regression analysis. According to the analysis, women had high passive (p<0.05) and exclusive (p<0.01) marriage value view, while men had high active (p<0.01) and instrumental (p<0.05) marriage value view. According to the analysis, it turns out that people who value interpersonal relationships during health promotion have a positive effect on romantic (t=2.383, R2=.257, p=.019) and instrumental (t=2.201, R2=.120, p=.030) marriage value view. Hygiene has been appeared to affect Passive marriage value view (t=3.001, R2=.111, p=.003) and Exclusive marriage value view (t=3.765, R2=.122, p=.000). Nutrition has been appeared to affect conservative marriage value view (t=2.086, R2=.118, p=0.039). Exercise has been appeared to affect conservative marriage value view (t=2.456, R2=.118, p=0.015) and active marriage value view (t=2.261, R2=.168, p=0.025). Through this study, in order to increase for the desire of marriage, marriage values need to be organized differently between men and women in marriage value programs and it suggested that health promotion behavior be included in programs that enhance the value of marriage.

Correlation Analysis between BMI and Bone Density in Menopause Women (폐경여성의 BMI와 골밀도의 상관관계 분석)

  • Kim, Hyeon-Jin
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.1015-1020
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    • 2021
  • This study retrospectively analyzed the test results of 113 healthy postmenopausal women without special diseases among patients who visited a medical institution in Busan from January 2020 to June 2021. The purpose of the study was to investigate the effect of BMI (Body Mass Index) on bone density in menopause women, the analysis of the lumbar and femur of patients with low weight (BMI<18.5) showed a significant probability (p-value) of 0.000, and the normal weight (18.5≦BMI<23.0) of the femur. In overweight (23.0≦BMI<25.0), the significance probability (p-value) of the lumbar region was 0.021 and the significance probability (p-value) of the femur was 0.034, confirming the correlation. However, in patients with high obesity (30.0≦BMI<40.0), the p-value of the lumbar region was 0.127, and the p-value of the femur was 0.093, indicating that there was no correlation between BMI and bone density.

Posttraumatic Stress in Fire fighters (소방대원의 외상후 스트레스 실태)

  • Koh, Bong-Yeun
    • The Korean Journal of Emergency Medical Services
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    • v.12 no.3
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    • pp.5-15
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    • 2008
  • Purpose : This study is a descriptive research to provide basic factors of posttraumatic stress in Firefighters. This study was carried out to develop the effective program for the fire fighters to cope with the posttraumatic stress following the disasters. Methods : The questionnaires were collected among fire fighters who serviced in K and I community from April 1 to June 30 in 2008. Total 304 questionnaires were analyzed by SPSS WIN program for descriptive statistics, Pearson's correlation coefficient and t-test. Results : 1. 48.0% of 300 fire fighters were at the age of 31-40, and 42.3% were under 30. 2. Work burden had a significant difference of 2.30 in low-risk group, 2.60 in high-risk group(t-value=-3.85, p=0.00). However, life event had no significant difference 0.79 event in low-risk group, 1.41 event in high-risk group(t-value=-2.27, p=0.24). 3. Concerning posttraumatic stress factors, there was positive correlation between mobilization impact level r=0.38(P<0.01), work burden r=0.38(p<0.01), and life event r=0.27(p<0.01). 4. According to the Symptom Check List-Revised(SCL-90-R), somatization had a significant differences(t-value=5.46, p=0.00), obsessive-compulsive(t-value=7.16, p=0.00), interpersonal sensitivity(t-value=6.15, p=0.00), depression(t-value=6.62, p=0.00), anxiety (t-value=7.33, p=0.00), hostility(t-value=5.94, p=0.00), phobia anxiety(t-value=6.85, p=0.00), paranoid ideation(t-value=5.55, p=0.00), psychotism(t-value=6.52, p=0.00) in low-risk and high-risk group. Conclusion : As a consequence, mobilization impact, work burden, and life event were the influential factors on posttraumatic stress. Also, high-risk group revealed significantly higher score on all 9 scales. The information obtained from surveys made recommendation to develop the intervention of stress management to control mobilization impact and posttraumatic stress.

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Lifestyle and Sporadic Colorectal Cancer in India

  • Sinha, Rupal;Doval, Dinesh Chandra;Hussain, Showket;Kumar, Kapil;Singh, Shivendra;Basir, Seemi Farhat;Bharadwaj, Mausumi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7683-7688
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    • 2015
  • Background: The study evaluated the patient, lifestyle and tumor profile in patients undergoing upfront surgery for sporadic colorectal cancer (CRC) in Indian population. Materials and Methods: One hundred consecutive patients were included. Details related to their demographic profile, habits, signs and symptoms, tumor profile, further treatment and follow up were recorded. Results: The majority of the patients had colonic cancer (68%), advanced tumor stage 3 & 4 (46%), moderately differentiated tumors (70%) with absence of lymphatic invasion (60%) and metastasis (90%). Correlations between tumor location and abdominal pain (p-value 0.002), bleeding per rectum (p-value <0.001), difficulty in micturition (p-value 0.012) and constipation (p-value 0.007) were found to be statistically significant. Abdominal pain was more frequently reported in patients with metastasis (p-value 0.031). Loss of weight statistically correlated with absence of lymphatic invasion (p-value 0.047). Associations between tumor stage and alcohol intake (p-value 0.050) and non vegetarian diet (p-value 0.006); lymphatic invasion and intake of spicy food (p-value 0.040) and non vegetarian diet (p-value 0.001) and metastasis and alcohol intake (p-value 0.041) were also observed. Age and tumor grade were also correlated (p-value 0.020). Conclusions: Minimizing the adverse lifestyle factors can help in reducing the overall incidence of CRC in the Indian population.

Factors associated with the Prevalence of Depression and Suicidal Ideation among Single-Person Households (1인 독거가구 중 우울증 유병과 자살생각에 영향을 미치는 요인)

  • Kim, Jae Hyun
    • The Journal of the Korea Contents Association
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    • v.22 no.1
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    • pp.611-619
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    • 2022
  • This study utilized the data from 2017, 2019 Korean National Health and Nutrition Survey to analyze the factors influencing depression and suicidal ideation among single-person households. For the analysis, demographic and economic variables as well as health status/behavior variables were considered. Activity restriction (OR: 4.753, p-value: <.0001) and smoking status (OR: 2.013, p-value: 0.044) were significantly associated with depression, and in terms of suicidal ideation, household income (OR: 3.526, p-value: 0.043), subjective health status (OR: 2.945, p-value: 0.007), activity restriction (OR: 2.263, p-value: 0.003) and smoking status (OR: 2.000, p-value: 0.023) showed significant association. In this regard, single-person households are likely to experience psychological angst, and further experience mental problems due to socio-economic and physical crisis. Therefore, it is necessary to establish a social network system in the community to detect those in need and provide appropriate interventions to prevent harmful outcomes.

Molasses clarifying method used by lime-phosphate for yeast culture (효모배지용 당밀의 청징법에 관하여)

  • 임억규
    • Korean Journal of Microbiology
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    • v.19 no.3
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    • pp.121-127
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    • 1981
  • The constituents of molasses and effect of pH precipitate formation in molasses solution, vary according to its producing districts. The formation of precipitation is not so changeable in the range of buffering zone of molasses solution(pH4.3-6.3) in philippine molasses according to the change of pH value. On lower or higher than the range of buffering zone, the precipitation is increased from pH 4.3 to 2.8 and from 6.3 to 8.1, it is decreased when pH value is lower or higher than the pH value range. For molasses clarifying, it had better adjust the pH of molasses solution to neutral or weak alkali range out of the alkai side of the buffering zone, with lime solution. And then, add the calcium super phosphate solution to pH value of alkali side in buffering zone, as much as the pH of clarified molasses solution can reach to middle value in buffering zone. For the equilibrium of pH value on clarifying molasses, it takes plenty of time more than 6 hours.

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No Association of the TGF-β1 29T/C Polymorphism with Breast Cancer Risk in Caucasian and Asian Populations: Evidence from a Meta-Analysis Involving 55, 841 Subjects

  • Alqumber, Mohammed A.A.;Dar, Sajad Ahmad;Haque, Shafiul;Wahid, Mohd;Singh, Rohit;Akhter, Naseem
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8725-8734
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    • 2014
  • The transforming growth factor-${\beta}1$ (TGF-${\beta}1$) gene 29 T/C polymorphism is thought to be associated with breast cancer risk. However, reports are largely conflicting and underpowered. We therefore conducted a meta-analysis of all available case-control studies relating the TGF-${\beta}1$ 29T/C polymorphism to the risk of developing breast cancer by including a total of 31 articles involving 24,021 cases and 31,820 controls. Pooled ORs were generated for the allele contrasts, with additive genetic, dominant genetic and recessive genetic models. Subgroup analysis was also performed by ethnicity for the TGF-${\beta}1$ 29T/C polymorphism. No association was found in the overall analysis (C vs T: OR=1.028, 95% CI=0.949-1.114, p-value 0.500; CC vs TC: OR= 1.022, 95% CI=0.963-1.085, p-value 0.478; CC vs TT: OR= 1.054, 95% CI=0.898-1.236, p-value 0.522; CC vs TT+ TC: OR= 1.031, 95% CI=0.946-1.124, p-value 0.482; TT vs CC+TC: OR= 0.945, 95% CI=0.827-1.080, p-value 0.403). Similarly, in the subgroup analysis by ethnicity, no association was found in Caucasian (C vs T: OR= 1.041, 95% CI=0.932-1.162, p-value 0.475; CC vs TC: OR= 1.031, 95% CI=0.951-1.118, p-value 0.464; CC vs TT: OR= 1.081, 95% CI=0.865-1.351, p-value 0.493; CC vs TT+TC: OR= 1.047, 95% CI=0.929-1.180, p-value 0.453; TT vs CC+TC: OR= 0.929, 95% CI=0.775-1.114, p-value 0.429;) and Asian populations (C vs T: OR= 1.004, 95% CI=0.908-1.111, p-value 0.931; CC vs TC: OR= 0.991, 95% CI=0.896-1.097, p-value 0.865; CC vs TT: OR= 1.015, 95% CI=0.848-1.214, p-value 0.871; CC vs TT+TC: OR= 1.000, 95% CI=0.909-1.101, p-value 0.994; TT vs CC+TC: OR= 0.967, 95% CI=0.808-1.159, p-value 0.720;). No evidence of publication bias was detected during the analysis. No significant association with breast cancer risk was demonstrated overall or on subgroup (Caucasian and Asian) analysis. It can be concluded that TGF-${\beta}1$ 29T/C polymorphism does not play a role in breast cancer susceptibility in overall or ethnicity-specific manner.