• 대한화학회지
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• 제58권3호
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• pp.283-288
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• 2014

A column solid phase extraction procedure based on modified polyurethane foam (PUF) by a newly synthesized Schiff base ionophore, named 2,2'-{iminobis[propane-3,1-diylnitrilo(1E)prop-1-yl-1-ylidene]}diphenol, was developed for preconcentration step of trace amounts determination of copper ions in water samples by atomic absorption flame spectroscopy. The influence of parameters on the adsorption process such as sample pH, amount of modified PUF packed in the column, type and volume of stripping reagent and its flow rate were investigated and optimized. Under optimum experimental conditions, the calibration graph was linear in a relatively wide range ($0.005-210{\mu}g/ml$) with a limit of detection $0.002{\mu}g/ml$ of copper. The proposed method allows achieving to a concentration factor of >133. The capacity of a column (1.6 cm i.d.) packed by 6 g of PUF modified by 12 mg of the Schiff base was found to be $247.7({\pm}2.1){\mu}g$ of copper. It was found that the adsorption process was highly selective towards copper ions with respect to some associated metal ions. The presented procedure was successfully applied for determination of copper in some water samples.

• 한국안전학회지
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• 제30권4호
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• pp.26-31
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• 2015

The purpose of this paper is to measure the induced voltage of the downscaled and simulated overhead ground wire of a 22.9kV-Y distribution line. This study performed a test of the downscaled and simulated distribution line according to whether it is grounded or not and the value of the ground resistance. In order to verify the reliability of the data measured by the test, the data was analyzed using the Minitab 17 program. It was found that the induced voltage of the downscaled and simulated distribution line is influenced by the value of the ground resistance. It was also found that the ground resistance obtained at a certain point is closely related to whether electric poles are grounded or not. The analysis results of the measured test data with a statistical method showed that the Anderson Darling (AD) was analyzed to be the smallest as 0.188 when the ground resistance of the electric poles had been maintained at $10{\Omega}$. In addition, the P value analyzed to be 0.894 which is in the proximity of the theoretical value of 1 and verified the reliability of the test data. It could be seen that the data measured by the downscaled simulation test forms a linear graph. It is thought that if a distribution line is installed in the same manner as the downscaled, simulated distribution line, the mean induced voltage will be reduced and reliability will be increased.

• Journal of Animal Science and Technology
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• 제59권5호
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• pp.12.1-12.7
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• 2017

Background: Despite the widespread use of dexamethasone in veterinary and human medicine, it is reported to cause some severe pregnancy related side effects like abortion in some animals. The mechanism of the response is not clear but seems to be related to interspecies and/or breed difference in response which may involve alterations in the concentrations of some reproductive hormones. Methods: Twenty Sahel goats comprising 18 does and 2 bucks were used for this study. Pregnancies were achieved by natural mating after synchronization. Repeated dexamethasone injections were given at 0.25 mg/kg body weight. Blood samples were collected biweekly for hormonal assay. Uterine biopsies were harvested at days 28 and day 78 of gestation through caesarean section for immunohistochemical analysis using 3 pregnant does randomly selected from each group at each instant. Data were expressed as Means ${\pm}$ Standard Deviations and analyzed using statistical soft ware package, GraphPad Instant, version 3.0 (2003) and progesterone receptor (PR) were scored semi-quantitatively. Results: Dexamethasone treatments had no significant (p > 0.05) effect on progesterone and estrogen concentrations in pregnant Sahel goats but up regulated PR from 2+ to 3+ in second trimester. Conclusion: As dexamethasone adverse effect on placenta is an established fact, the lack of effect on progesterone level in this study may be due to the fact that unlike other species whose progesterone production during pregnancy is placenta - dependent, in goats is corpus luteum - dependent. Consequently dexamethasone adverse effect on placenta reported in literatures did not influence progesterone levels during pregnancy in Sahel goat. The up regulation of progesterone receptor (PR) in Sahel goat gravid uterus is a beneficial effects and that dexamethasone can safely be used in corpus luteum - dependent progesterone secreting pregnant animal species like Sahel goat and camel. Therefore source of progesterone secretions during pregnancy should be considered in clinical application of dexamethasone in pregnancy.

• 동의생리병리학회지
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• 제17권6호
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• pp.1533-1537
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• 2003

This double-blind randomized clinical trial was performed to evaluate the anti-anxiety, anti-stress effect of a modified formula WS-01 consisted with several herbs(Jujubae Fructus. Longanae Arillus. Poria Cocos) and germinated rice. The extract of the formula was administered (p.o) to 24 students and placebo was to 23 students for 4 weeks. STAI-KYZ(Hahn. Hakjisa), ABR2000(Meridian, Korea), CBC, LFT, U/A were checked before and after the administration period. There was no difference between the STAI score of WS-01 and that of placebo group in first test. But the STAI state anxiety score was 5.33±7.33 reduced in WS-01 group and it was 0.52±6.42 increased in placebo group in second test. this result was significant stastically. 10 students in WS-01 group showed improving result, but only 1 student in placebo group showed improving result of ABR2000 test. The result of ABR2000 was analyzed with curve 2, Regulation 2, and graph 1,2,3, because those reflect central nerve system and stressful condition of the body. There was no significant result in first and second CBC, LFT, Urine test. The results of this clinical study suggest that WS-01 has anti-anxiety, anti-stress effect, and it could be applied to various conditions or disorders related with anxiety and stress.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1547-1551
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• 2016

Background: Acute myeloid leukemia (AML) is a clonal hematopoietic disorder resulting from genetic alterations in normal hematopoietic stem cells. The aim of this study was to evaluate prognostic factors and survival of AML patients in the Northeast of Iran. Materials and Methods: This retrospective study covered 96 patients with AML referred to Emam Reza Hospital, Mashhad city, Iran, from 2009 to 2015. Age, sex, blood group, type of AML, fever, consumption of amphotericin B, cytogenetic forms and survival were analyzed. Also, WBC, hemoglobin and platelet levels were checked. Mean follow-up was 30.5 months (60.4% mortality). Survival was plotted by GraphPad Prism 5 with Log-rank test. Results: The mean age for all AML patients at diagnosis was 40.4 years (range, 17-77 years). Some 42.7% patients were aged <35 years and 40.6% were male. In all patients, 76% had fever and 50% consumed amphotericin. T(15;17)(q22;q21) had the most prevalence (37.7%) compared to other forms. Out of 92 patients, O+(30.4%) was the most common blood group and AML-M5 (28.3%) the most common subtype. There was a significant difference in survival based on WBC and consumption of amphotericin B (P<0.05). Conclusions: WBC level, fever and consumption of amphotericin B proved to be factors for survival of AML patients. The mean age for patients in Iran is lower than other areas in the World and also survival in this study was higher than in other studies.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.979-984
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• 2015

Breast cancer is the leading cause of morbidity and mortality globally but has an even more significant impact in developing countries. Pakistan has the highest prevalence among Asian countries. A general lack of public awareness regarding the disease often results in late diagnosis and poor treatment outcomes. The literacy rate of the Southern Punjab (Pakistan) is low compared to its Northern part. It is therefore vital that university students and especially medical students develop a sound knowledge about the disease so that they can spread awareness to others who may be less educated. This study therefore considers current knowledge and understanding about the early signs of breast cancer amongst a study group of medical and non-medical university students of the Southern Punjab, Pakistan. A cross-sectional descriptive analysis of the university students was carried out using a self-administered questionnaire to assess their awareness of breast cancer from March to May 2014. A total of 566 students participated in this study, out of which 326 were non-medical and 240 were from a medical discipline. Statistical analysis was carried out using Graph Pad Prism Version 5 with a significance level set at p<0.05. The mean age of the non medical and medical participants was 23 (SD 2.1) and 22 (SD 1.3) years, respectively. Less than 35% students were aware of the early warning signs of the breast cancer development. Knowledge of medical students about risk factors was significantly better than the non medical ones, but on the whole was insufficient. Our study indicated that knowledge regarding breast cancer was generally insufficient amongst the majority of the university students (75% non-medical and 55% medical) of Southern Punjab, Pakistan. This study highlights the need to formulate an awareness campaign and to organize conferences to promote breast cancer awareness among students in this region.

• Journal of Gastric Cancer
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• 제15권4호
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• pp.256-261
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• 2015

Purpose: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer. Materials and Methods: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software. Results: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study. Conclusions: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

• 대한영양사협회학술지
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• 제22권3호
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• pp.214-224
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• 2016

The purpose of this study was to assess the physical activity of preschool children using an accelerometer and investigate differences related to epoch length setting during use of the accelerometer. Subjects of the study were 26 children (12 boys and 14 girls) at the age of 5, enrolled in one preschool located in Gangneung. From 9:00 a.m. to 4:00 p.m. (7 hours period), every child wore a total of four accelerometers (ActiGraph $GT3X^+$, USA), including three attached to the left hip (with epoch length set at 5 seconds, 15 seconds, and 30 seconds). For comparison purposes, a forth was attached to the opposite position, with epoch length set at 5 seconds. Data collected using 15s epoch and 30s epoch (single larger epoch) were compared with those obtained after reintegration of 5s to 15s epoch, 5s to 30s epoch, and 15s to 30s epoch, respectively (smaller epochs reintegrated). According to the results of this study, there were no significant differences in VM between 30s epoch and 5s to 30s epoch reintegrated and in MVPA (moderate-to-vigorous physical activity), between 15s epoch and 5s to 15s epoch reintegrated. From the Bland-Altman plot, reintegration of 15s to 30s epoch in VM and reintegrations of 15s to 30s epoch and 5s to 15s epoch in MVPA can be recommended for assessing physical activity in preschool children. Further research is needed into the reintegration method while using an accelerometer for assessment of energy expenditure in children.

• Journal of Preventive Medicine and Public Health
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• 제52권2호
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• pp.101-108
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• 2019

Objectives: To objectively determine and compare the physical activity (PA) levels of adults newly diagnosed with type 2 diabetes (T2D) and adults without T2D in Vietnam using an accelerometer. Methods: A total of 120 participants with newly diagnosed T2D and 120 adults without T2D were recruited from a large hospital in Hanoi, the capital city of Vietnam. All participants wore an ActiGraph GT3X accelerometer for at least 5 days, including 1 weekend day. Freedson cut-off points were used to estimate different intensities of PA. In addition, comparisons between groups were made with respect to achieving the World Health Organization (WHO) and International Diabetes Federation (IDF) recommended PA guidelines. Results: Men with T2D had significantly lower levels of PA than men without T2D. The respective multivariable-adjusted mean values of daily step count, daily light-intensity, moderate-intensity, and moderate-to-vigorous-intensity PA were approximately 14%, 19%, and 22% lower in the men with T2D than in their non-T2D counterparts. However, women with T2D accumulated a greater number of steps per day than women without T2D. Only 59.2% of the adults with T2D met the minimum recommended level of PA (WHO and IDF), compared to 74.2% of adults without T2D (p<0.05). After adjusting for potential confounders, participants with T2D experienced 50.0% significantly lower odds of achieving PA recommendations. Conclusions: Vietnamese men with T2D were less physically active than those without T2D, and adults with T2D were less likely to meet PA guidelines. The results suggest a need for integrating PA into the self-management of this chronic condition.

• 한국정보통신학회논문지
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• 제26권5호
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• pp.743-754
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• 2022

본 논문은 양식장의 환경 데이터 모니터링 시스템 개발 및 성능 평가 결과를 담고있다. 하드웨어 개발을 위해 용존 산소량, 질소 이온 농도, 염도 및 해수 온도 데이터 수집을 위한 아날로그 센서들과 외부 온습도 및 위치 정보를 수집하기 위한 디지털 센서들을 이용하였으며, 이들 수집 데이터들을 클라우드 기반의 Firebase DB에 전달하기 위한 통신 모듈로 LoRa 송수신 세트를 이용하였다. Firebase에 저장되는 수집 데이터들은 웹 브라우저와 모바일 단말기 상에서 그래프 형태로 출력해 양식장 환경 데이터 변화를 실시간으로 관찰할 수 있도록 하였으며, 임계치를 지정해 수집 데이터가 이 범위를 벗어나는 경우 모바일 단말기 상에 실시간 알림이 도착하도록 구현하였다. 개발 시스템의 성능 평가를 위해 하드웨어 모듈에서부터 웹/모바일 애플리케이션까지 타임 스탬프 기반의 응답 시간을 측정한 결과 6.2초에서 6.85초 사이의 변화를 보여주고 있어 만족할 만한 결과임을 알 수 있었다.