• Journal of Korean Academy of Nursing
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• v.22 no.1
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• pp.49-67
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• 1992

Most hospitalized children will experience physical pain as well as psychological distress. Preschool children's pain perception related to painful procedures can increase due to elevated anxiety and fear because they do not have understanding logical of their disease and hospitalization. In particular, they are distressed about needle - related procedures which are feared because they are seen to be a cause of bodily damage. This descriptive study attempted to identify pain perception levels in preschool children and their mothers. A self-reporting measurement and behavioral observation were used to collect the data. A total of 25 hospitalized preschool children and their mothers were investigated and data were collected about 60 painful procedures. Data collection was carried out by the researcher and two trained investigators from November first to December tenth. Three insruments were used to collect the data : Faces Pain Rating Scale(FPRS) developed by Beyer was used to measure the degree of preschool children's pain perception about painful procedures. The Visual Analogue Scale(VAS) devised by Huskisson was used to assess the degree of mothers' pain perception about their children's painful procedures. A Pain Behavioral Checklist based on the Procedure Behavior Check List by LeBaron and Zelter and modified by the researcher was used to observe behaviors of preschool children, their mothers, and nurses when the painful procedures took place. The data were analyzed by an SPSS program, and were tested using real numbers, percentages, Pearson correlation coefficient, t-test, and ANOVA. The results of this study are as follows : 1. Of all the painful procedures, the mean score for the FPRS for the preschool children's pain perception was 4.02 points, and the mean score for the VAS of mothers' pain perception was 10.92 points. 2. A Positive correlation which was statistically significant was found between the pain perception of preschool children and their mothers (r＝.53, p＜.01). that is, the higher the children's pain perception was, the higher their mothers' pain perception was. 3. The characteristics of the painful procedures related with children's pain perception as follows : The type of painful procedure was found to be statistically significant (F＝23.44, p＜.01), Among the three procedures Ⅳ starting was found to be perceived as the most painful procedures to the children. The greater the number of times that the procedure had been done, the higher the pain perception was (F＝4.44, p＜.01), and the longer the duration of the procedure, the higher the pain perception wa(r＝.30, p＜.05). Pain perception in the treatment room was higher than in the children's room(t＝6.30, ＜.01), pain perception in the mother's presence was the higher than when the mother was not present (t＝2.91, p＜.01). 4. The characteristics of the painful procedures related with the mothers' pain perception as follows : The type of painful procedure was found to be statistically significant(F＝6.01, p＜.01). Among the three procedures Ⅳ sampling was found to be perceived as the most painful procedures to the mothers. The greater the number of times that the procedure had been done, the higher the pain perception was (F＝5.95, p＜.01), and the longer the duration of the procedure, the higher the pain perception was (r＝.31, p＜.05). Pain perception in the treatment room was higher than in the children's room (t＝3.51, p＜.01), but pain perception in the mother's presence showed statistically significant no difference. 5. Of all of the 19 children's behaviors during the painful procedures, the most frequent behaviors observed Were as follows in order of frequency “crying”, “screamirig”, “facial grimacing”, “physical resistance”, Of all of the nine methers' behaviors, the most frequent by observed in “console children”, “hold children”, “applaud children”, Of all of the 11 nurses' behaviors during the painful procedures, the mast frequent in order were “smiling”, “physical restraint”, “console children”, “praise children”. 6. A positive correlation between children's and mothers' pain perception and children's behaviors was found to be statistically significant (r＝.65, p＜.01, r＝67, p＜.01). Also the relationship between children's and mothers' pain percertion, and mothers' behavior was found to be statistically significant (r＝.57, p＜. 01, 4＝.60, p＜.01). The relationship between children's pain perception and nurses' behaviors was also found to be statistically significant (r＝.46, p＜.01), but there was difference between mothers' pain perception and nurses' behaviors.

• Journal of Korean Academy of Nursing
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• v.18 no.1
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• pp.80-93
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• 1988

This study was planned and carried out to investigate the correlation between premenstrual syndrome and personality in order to provide informations basic to the prevention, alleviation, and care for the premenstrual syndrome. Data on premenstrual syndrome were gatherd from October 20 to 25, 1986 by questionnaire modified by the researcher based on Endicott's Premenstrual Assessment Form. Reliability of the instrument was tested by Cronbach's $\alpha$. Data on personality were gathered in March, 1986, by the high school autorities by standardized Personality Inventory Scale developed by Eung Yun Hwang were used. Subjects numbered 457, 95.2% of the first grade students of H. Girls High School located in Seoul. The correlation and difference between personality traits and premenstrual syndrome analysed by Pearson's Correlation Coefficient, and difference between groups were analysed by the t-test. Personality traits influencing premenstrual syndromal categories were analysed by the multiple regression. The results are as follows : I. The five highist categories of premenstrual syndrome among 18 categories revealed to be Social withdrawal, General discomfort, Lability, Fatigue and Hostility / Anger in rank order. II. Personality traits and Premenstrual syndrome ; 1. Tendency of Psychoneuroses(r＝0.43, p＜.001), psychoses(r＝.39, p＜.001) and anti-social behaviors (r＝0.43, p＜.001) revealed to be significantly correlated to premenstrual syndrome. Hypothesis 1 is accepted. 2. Emotional stability(r＝ -0.38, p＜.001), reflectiveness (r＝ -0.14, p＜.01), masculinity (r＝ -0.10, p＜05) and antonomy (r＝ -0.12, p＜.05) revealed significant correlation, While activity, dominance, sociability and achivement revealed no significant correlation. Hypothesis 2 is partially accepted. III. Significant models of personality traits influencing the premenstrual syndromal categories are ; 1. 5 personality traits : tendency of psychoneuroses, emotional stability, dominance, activity and autonomy revealed to influence Low mood / loss of pleasure significantly. ($R^2$＝.19) 2. 3 personality traits ; tendency of psychoneuroses, emotional stability and sociability revealed to influence Lability significantly. ($R^2$＝.15) 3. 5 personality traits ; tendency of psychoneuroses, activity, emotional stability, sociability and achievement revealed to influence Anxiety significantly.($R^2$＝.18) 4. 3 personality traits : tendency of psychoneuroses, emotional stability and sociability revealed to influence Miscellaneous mood / behavior changes significantly.($R^2$＝.18) 5. 3 personality traits : tendency of psychoneuroses, psychoses and reflectiveness revealed to influence Hysteroid features significantly.($R^2$＝.16) IV. No significant correlation between irregularity of menstruation and premenstrual syndrome was revealed. No significant difference between group of dysmenorrhea and group of non-dysmenorrhea in premenstrual syndrome was revealed.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.77-86
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• 2020

The research was to identify difference of values of the self-esteem, resilience and quality of life of hemodialysis patients. The survey was conducted to collect data between February 1 and 28 of 2020. SPSS/WIN 20 program was used to perform descriptive, correlation, and multiple regression analyses. In the correlation analysis, Cohabitation form(r=.262, p<.01), Economic status(r=.278, p<.01), Current health status recognition(r=.294, p<.01), Self-esteem(r=.547, p<.01), Resilience(r=637, p<.01) turned out to be influential factor for self-esteem, resilience, and quality of life according to general and disease of characteristics. Therefore, on the basis of this research, it is meaningful to provide basic data for the development of nursing interventions that allow one to embrace one's health condition and find the meaning of life in order to improve the quality of life of hemodialysis patients.

• Korean Parent-Child Health Journal
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• v.4 no.2
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• pp.16-31
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• 2002

This study was done in order to analyze the relationship of gender identity, self-esteem, self-efficacy, hardiness, and health promotion behavior in the College Women. The subjects were 275 students from a college in Kyungbuk. The instruments used for this study were made of general characteristics(6 items), gender identity(1 item), self-esteem(10 item), self-efficacy(13 items), hardiness(38 items) and health promoting behaviors(40 items). The data were analyzed by SPSS/$PC^+$ program using descriptive statistics, Pearson's Correlation Coefficient and Multiple Stepwise Regression. The results of this study were as follows. 1. The Mean score of gender identity, self-esteem, self-efficacy, hardiness, and health promotion behavior were as follows. 1) The mean score of the health promoting behavior was 2.24. Among the subcategories, the highest score was interpersonal support(2.91), self-actualization (2.85), and the lowest score was health responsibility(1.62). 2) The mean score of the gender identity was 2.04. 3) The mean score of the self-esteem was 2.85. 4) The mean score of the self-efficacy was 6.50. 5) The mean score of the hardiness was 2.83. 2. Correlations of gender identity, self-esteem, self-efficacy, hardiness, and health promotion behavior were as follows. 1) Gender identity was positively correlated with self-esteem(r=-.287, p=.0000), self-efficacy(r=-.226, p=.0000), hardiness(r=.237, p=.0000), health promotion behavior(r=-.236, p=.0000). 2) Self-esteem was positively correlated with self-efficacy(r=.499, p=.0000), hardiness (r=-.275, p=.0000), health promotion behavior(r=.428, p=0000). 3) Self-efficacy was positively correlated with hardiness(r=-.423, p=.0000), health promotion behavior(r=.492, p=.0000). 4) Hardiness was positively correlated with health promotion behavior(r=-.457, p=.0000). 4. Self-efficacy, hardiness and self-esteem were the major predictors for health promoting behavior(35.7%).

• BMB Reports
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• v.52 no.9
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• pp.572-576
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• 2019

Bisphosphonates are the mainstay of therapy worldwide for osteoporosis. However, bisphosphonates also have limitations. The objective of this study was to determine the role of miR-101-3p/Rap1b signal pathway in osteoclast differentiation after treatment with bisphosphonates. Our results revealed that miR-101-3p was an important regulator in bisphosphonates treated-osteoclasts. When miR-101-3p was down-regulated in bone marrow-derived macrophage-like cells (BMMs), the development of mature osteoclasts was promoted, and vice versa. However, alendronate decreased multinucleated cell number regardless of whether miR-101-3p was knocked down or over-expressed. TRAP activity assay confirmed the above results. Luciferase assay indicated that miR-101-3p was a negative regulator of Rap1b. Western blot analysis revealed that protein expression level of Rap1b in BMMs transfected with OV-miR-101-3p was lower than that in BMMs transfected with an empty vector. Rap1b overexpression increased TRAP-positive multinucleated cells, while Rap1b inhibition decreased the cell numbers. In vivo data showed that miR-101-3p inhibited osteoclast differentiation in ovariectomized mice while overexpressed of Rap1b blocked the differentiation. Taken together, our data demonstrate that miR-101-3p/Rap1b signal pathway plays a key role in osteoclast differentiation after treatment with bisphosphonates.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7239-7247
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• 2014

This study repeated low-frequency transcranial magnetic stimulation (rTMS) to evaluate the effects on cognitive function in chronic stroke patients. Among the chronic stroke patients, 30 patients selected by MMSE-K and BCRS-K were divided randomly into 3 groups. Group I (n=10) had only sound applied, group II (n=10) were applied 1 Hz rTMS on the damaged side and group III (n=10) were applied to 1 Hz rTMS on the opposite side for total 2 weeks, 20 minutes per a day, five times per a week. To examine the change in cognitive function, CREAD-K scores were measured before, 1 week, 2 weeks, and then 3 months after the intervention. The CREAD-K scores were measured before and 1 week, 2 weeks and 3 months after the interventions. The immediate recall memory showed a significant difference after 2 weeks and 3 months in groups II and III (p<.05), The recognition memory showed a significant difference after 2 weeks and 3 months in group III (p<.05). The delayed recall memory showed significant differences after 3 months in group III than in group I (p<.05). Therefore, the application of low-frequency rTMS has a positive influence on the cognitive rehabilitation of chronic stroke patients.

• Current Research on Agriculture and Life Sciences
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• v.12
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• pp.69-82
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• 1994

This study was conducted to investigate the physiological characteristics and to isolate plasmid DNA of R. japonicum strains. The results obtained were as follows; Strains S117, S118, 005, 011 and DY-1 were slow-growers and showed alkaline reaction, whereas strains S110, S111, S114, S116, S120 and 010 were fast-growers and produced acid reaction in YEM broth. All the fast- and slow-growing R. japonicum showed gram negative and formed mucous white colony on agar plate. After 7 days, the colonies of the fast-growers were between 2.0 and 4.0mm in diameter, whereas those of slow-growers were approximately between 0.5 and 1.5mm. The fast-growers were uniformly sensitive to the pH of 4.5 and tolerant of the pH of 9.5, whereas the reverse was found for the slow-growers. All the fast-growers were able to grow in the presence of 2% NaCl however the slow-growers were not grown. All the microorganisms grew rapidly in simple mineral salt medium containing as the sole source of carbon. Starch was rarely utilized. All the fast-growers utilized sucrose. The slow-growing R. japonicum strains examined usually contained 1 to 3 plasmid DNA ranging between 15Kb and 250 Kb, whereas the fast-growing R. japonicum strains contained 1 to 3 plasmid DNA ranging from 20 Kb to 250Kb.

• Journal of the Korean Applied Science and Technology
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• v.37 no.5
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• pp.1430-1440
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• 2020

The purpose of this study was to identify relationships between the awareness of well-dying, advance directives knowledge and attitude, according to patient's terminal care experience among nursing students. Participants were 321 nursing students, selected from 3 universities located in Gyeonggi-do, Chungcheong-do, Jeolla-do and data were collected using self-reported questionnaires. Data were analyzed using the SPSS/WIN 25.0 program, with descriptive statistics x²-test, t-test, ANOVA, Scheffe' test, Pearson's correlation coefficient. There was a significant difference in advance directives attitude among nursing students with experience of patient's terminal care or no experience of patient's terminal care (t=3.011, p<.003). In addition, the awareness of well-dying (r=.194, p=.008) and advance directives knowledge (r=.201, p=.006) were positively correlated with advance directives attitude in nursing students with experience of patient's terminal care, whereas advance directives attitude was positively correlated with the awareness of well-dying (r=.189, p=.029) in nursing students with no experience of patient's terminal care. This study suggests that there is a need for the development of systematic education programs to improve a positive attitude toward advance directives and awareness of well-dying of nursing college students.

• Korean Journal of Microbiology
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• v.46 no.3
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• pp.296-302
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• 2010

Microcystis (Cyanobacteria, Chroococcales) is one of the green tide-causing organisms in freshwaters, and some species produce microcystin that is hepatotoxin. In the aspects of freshwater quality controls and health concerns, therefore it is necessary to manage the harmful organisms. In the present study, RNA polymerase beta subunit (rpoB) gene sequences of Microcystis were determined and characterized in order to use a potential marker for the molecular detections of the species. Microcystis rpoB showed high divergences of DNA similarity and genetic distances when compared with those of 16S rRNA, and the molecular differences were statistically significant (Student t-test, p<0.05). Parsimony analyses showed the rpoB gene evolves more than 2-fold faster than 16S rRNA. In addition, phylogeny of the rpoB gene separated each M. aeruginosa strain more clearly compared with a 16S rRNA tree. This study found that the order Chroococcales, including Microcystis, has approximately two rRNA operons and single copy of the rpoB gene in their chromosomes. These results suggest that the rpoB gene is a useful marker for the molecular phylogenetics and the detection of Microcystis.

• Journal of Embryo Transfer
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• v.22 no.2
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• pp.111-114
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• 2007

This study was carried out to investigate the reproductive performance of average (less than 10,000 liters milk in 305 days) and high yielding (more than 10,000 liters milk in 305 days) Holstein cattle at commercial dairy herds (n=22). Data on milk progesterone (10 to 60 days postpartum), days to post-partum estrous, days to post-partum conception, service per conception and calving interval were recorded for two consecutive years. Post-partum milk progesterone concentration and days to reach peak milk progesterone concentration were similar in high and average yielding cows. High yielding cows took more days to show signs of first postpartum estrous than average yielding cows. Post-partum conception was 20 days earlier in average yielding cows than high yielding cows. Artificial insemination per conception was similar between average and high yielding cows. Calving interval was 26.9 days longer in high yielding cows compared to average yielding cows. In conclusion, better reproductive and feeding management may help improve the reproductive performance of high yielding dairy cattle in commercial dairy farms.