• Title/Summary/Keyword: P-S-R

Search Result 9,085, Processing Time 0.037 seconds

ON PRECISE ASYMPTOTICS IN THE LAW OF LARGE NUMBERS OF ASSOCIATED RANDOM VARIABLES

  • Baek, Jong-Il;Seo, Hye-Young;Lee, Gil-Hwan
    • Honam Mathematical Journal
    • /
    • v.30 no.1
    • /
    • pp.9-20
    • /
    • 2008
  • Let ${X_i{\mid}i{\geq}1}$ be a strictly stationary sequence of associated random variables with mean zero and let ${\sigma}^2=EX_1^2+2\sum\limits_{j=2}^\infty{EX_1}{X_j}$ with 0 < ${\sigma}^2$ < ${\infty}$. Set $S_n={\sum\limits^n_{i=1}^\{X_i}$, the precise asymptotics for ${\varepsilon}^{{\frac{2(r-p)}{2-p}}-1}\sum\limits_{n{\geq}1}n^{{\frac{r}{p}}-{\frac{1}{p}}+{\frac{1}{2}}}P({\mid}S_n{\mid}{\geq}{\varepsilon}n^{{\frac{1}{p}}})$,${\varepsilon}^2\sum\limits_{n{\geq}3}{\frac{1}{nlogn}}p({\mid}Sn{\mid}{\geq}{\varepsilon\sqrt{nloglogn}})$ and ${\varepsilon}^{2{\delta}+2}\sum\limits_{n{\geq}1}{\frac{(loglogn)^{\delta}}{nlogn}}p({\mid}S_n{\mid}{\geq}{\varepsilon\sqrt{nloglogn}})$ as ${\varepsilon}{\searrow}0$ are established under the suitable conditions.

Synthesis of L-threo-2,3-Dihydroxyphenylserine (L-threo-DOPS) by Thermostable L-Threonine Aldolase Expressed in Corynebacterium glutamicum R (Corynebacterium glutamicum에서 발현된 L-Threonine Aldolase를 이용한 파킨슨병 치료제 L-threo-2,3-Dihydroxyphenylserine (L-threo-DOPS)의 합성)

  • Baik, Sang-Ho
    • Microbiology and Biotechnology Letters
    • /
    • v.36 no.2
    • /
    • pp.128-134
    • /
    • 2008
  • In order to examine efficient L-threo-2,3-Dihydroxyphenylserine (L-threo-DOPS) synthesis process using whole cell biocatalyst, a thermostable L-threonine aldolase (L-TA), which cloned from Streptomyces coelicolor A3(2) and improved for stability, was expressed in a Corynebacterium glutamicum R strain. The constructed Corynebacterium expression vector, pCG-H44(1) successfully expressed L-TA in C. glutamicum R strain, but showed very low expression level. In order to improve the expression level, the expression vector named pCG-H44(2) was reconstructed by eliminating 1 nucleotide between SD sequence and start codon of L-TA. The pCG-H44(2) vector plasmid was able to overexpress L-TA approximately 3.2 times higher than pCG-H44(1) in C. glutamicum R strain (CGH-2). When the whole cell of CGH-2 was examined in a repeated batch system, L-threo-DOPS was successfully synthesized with a yield of 4.0 mg/ml and maintain synthesis rate constantly after 30 repeated batch reactions for 130 h.

The Effect of Stress on Emotional Intelligence of Nursing Students Experienced COVID-19 Situation: Focusing on the Mediating Effect of Resilience (COVID-19 상황을 경험한 간호대학생의 스트레스가 감성지능에 미치는 영향: 회복탄력성 매개효과를 중심으로)

  • Lim, Hyun-Suk;Ryu, Jeong-Lim
    • Journal of the Korea Convergence Society
    • /
    • v.12 no.11
    • /
    • pp.521-531
    • /
    • 2021
  • The aim of this was to examine the mediating effect of resilience in the relatioinship of stress to emotional intelligence in nursing students experienced COVID-19. The participants in this study were 179 nursing students in 3rd and 4th grade and data were collected using self-reported questionnaires. Data were analyzed using the SPSS/WIN 25.0 program, with descriptive statistics x2-test, t-test, ANOVA, Pearson's correlation. There were significant correlations between college based stress and emotional intelligence(r=-.33, p<.001), clinical based stress and emotional intelligence(r=-.31, p<.001), resilience and emotional intelligence(r=62, p<.001). Resilience showed partial mediating effects in the relationship between college-based stress and emotional intelligence. Resilience showed full mediating effects in the relationship between clinical-based stress and emotional intelligence(Z=-3.07, p<.001). Based on the findings of this study, the enhancement of resilience may positively affect the emotional intelligence of the nursing students, even while they are stress. Therefore, it is necessary to develop effective strategies to enhance resilience for stress.

A Study on the Construction Method selecting scheme using Fuzzy Relative Preference Ratio method (퍼지 R.P.R(Relative Preference Ratio)기법을 이용한 건설프로젝트의 공법선정에 관한 연구)

  • Lee Dong-Un;Kim Kyung-Whal
    • Korean Journal of Construction Engineering and Management
    • /
    • v.5 no.5 s.21
    • /
    • pp.143-150
    • /
    • 2004
  • Nowaday, The tendency of complexity and extension of construction fields increase the need for efficient works managements like a construction management. Consequently, by the introduction of Decision-Making Theories, researches for improving construction field's efficiencies are actively performed. Fuzzy Analytical Hierarchy Process method is invented, so that describes a decision maker's ambiguous linguistic judgment with fuzzy numbers. but most of researches on Fuzzy-AHP use symmetric triangular fuzzy function for estimating each evaluation item with the consequence that exact judgments are impossible. those limits are caused by the point that employed fuzzy ranking methods can not support dissymmetric fuzzy numbers. In this research, we aims to overcome this problem with R.P.R(Relative Preference Ratio) method and suggest improved Fuzzy-AHP method which can use dissymmetric fuzzy triangular numbers.

A study of pain perception related to IV therapy in hospitalized preschool children and their mothers (정맥주사와 채혈시 학령전기 아동과 어머니가 인지하는 동통)

  • 임지영
    • Journal of Korean Academy of Nursing
    • /
    • v.22 no.1
    • /
    • pp.49-67
    • /
    • 1992
  • Most hospitalized children will experience physical pain as well as psychological distress. Preschool children's pain perception related to painful procedures can increase due to elevated anxiety and fear because they do not have understanding logical of their disease and hospitalization. In particular, they are distressed about needle - related procedures which are feared because they are seen to be a cause of bodily damage. This descriptive study attempted to identify pain perception levels in preschool children and their mothers. A self-reporting measurement and behavioral observation were used to collect the data. A total of 25 hospitalized preschool children and their mothers were investigated and data were collected about 60 painful procedures. Data collection was carried out by the researcher and two trained investigators from November first to December tenth. Three insruments were used to collect the data : Faces Pain Rating Scale(FPRS) developed by Beyer was used to measure the degree of preschool children's pain perception about painful procedures. The Visual Analogue Scale(VAS) devised by Huskisson was used to assess the degree of mothers' pain perception about their children's painful procedures. A Pain Behavioral Checklist based on the Procedure Behavior Check List by LeBaron and Zelter and modified by the researcher was used to observe behaviors of preschool children, their mothers, and nurses when the painful procedures took place. The data were analyzed by an SPSS program, and were tested using real numbers, percentages, Pearson correlation coefficient, t-test, and ANOVA. The results of this study are as follows : 1. Of all the painful procedures, the mean score for the FPRS for the preschool children's pain perception was 4.02 points, and the mean score for the VAS of mothers' pain perception was 10.92 points. 2. A Positive correlation which was statistically significant was found between the pain perception of preschool children and their mothers (r=.53, p<.01). that is, the higher the children's pain perception was, the higher their mothers' pain perception was. 3. The characteristics of the painful procedures related with children's pain perception as follows : The type of painful procedure was found to be statistically significant (F=23.44, p<.01), Among the three procedures Ⅳ starting was found to be perceived as the most painful procedures to the children. The greater the number of times that the procedure had been done, the higher the pain perception was (F=4.44, p<.01), and the longer the duration of the procedure, the higher the pain perception wa(r=.30, p<.05). Pain perception in the treatment room was higher than in the children's room(t=6.30, <.01), pain perception in the mother's presence was the higher than when the mother was not present (t=2.91, p<.01). 4. The characteristics of the painful procedures related with the mothers' pain perception as follows : The type of painful procedure was found to be statistically significant(F=6.01, p<.01). Among the three procedures Ⅳ sampling was found to be perceived as the most painful procedures to the mothers. The greater the number of times that the procedure had been done, the higher the pain perception was (F=5.95, p<.01), and the longer the duration of the procedure, the higher the pain perception was (r=.31, p<.05). Pain perception in the treatment room was higher than in the children's room (t=3.51, p<.01), but pain perception in the mother's presence showed statistically significant no difference. 5. Of all of the 19 children's behaviors during the painful procedures, the most frequent behaviors observed Were as follows in order of frequency “crying”, “screamirig”, “facial grimacing”, “physical resistance”, Of all of the nine methers' behaviors, the most frequent by observed in “console children”, “hold children”, “applaud children”, Of all of the 11 nurses' behaviors during the painful procedures, the mast frequent in order were “smiling”, “physical restraint”, “console children”, “praise children”. 6. A positive correlation between children's and mothers' pain perception and children's behaviors was found to be statistically significant (r=.65, p<.01, r=67, p<.01). Also the relationship between children's and mothers' pain percertion, and mothers' behavior was found to be statistically significant (r=.57, p<. 01, 4=.60, p<.01). The relationship between children's pain perception and nurses' behaviors was also found to be statistically significant (r=.46, p<.01), but there was difference between mothers' pain perception and nurses' behaviors.

  • PDF

Premenstrual Syndrome and Personality (인생과 월경 전기 증후군과의 상관관계에 관한 연구)

  • 김은주
    • Journal of Korean Academy of Nursing
    • /
    • v.18 no.1
    • /
    • pp.80-93
    • /
    • 1988
  • This study was planned and carried out to investigate the correlation between premenstrual syndrome and personality in order to provide informations basic to the prevention, alleviation, and care for the premenstrual syndrome. Data on premenstrual syndrome were gatherd from October 20 to 25, 1986 by questionnaire modified by the researcher based on Endicott's Premenstrual Assessment Form. Reliability of the instrument was tested by Cronbach's $\alpha$. Data on personality were gathered in March, 1986, by the high school autorities by standardized Personality Inventory Scale developed by Eung Yun Hwang were used. Subjects numbered 457, 95.2% of the first grade students of H. Girls High School located in Seoul. The correlation and difference between personality traits and premenstrual syndrome analysed by Pearson's Correlation Coefficient, and difference between groups were analysed by the t-test. Personality traits influencing premenstrual syndromal categories were analysed by the multiple regression. The results are as follows : I. The five highist categories of premenstrual syndrome among 18 categories revealed to be Social withdrawal, General discomfort, Lability, Fatigue and Hostility / Anger in rank order. II. Personality traits and Premenstrual syndrome ; 1. Tendency of Psychoneuroses(r=0.43, p<.001), psychoses(r=.39, p<.001) and anti-social behaviors (r=0.43, p<.001) revealed to be significantly correlated to premenstrual syndrome. Hypothesis 1 is accepted. 2. Emotional stability(r= -0.38, p<.001), reflectiveness (r= -0.14, p<.01), masculinity (r= -0.10, p<05) and antonomy (r= -0.12, p<.05) revealed significant correlation, While activity, dominance, sociability and achivement revealed no significant correlation. Hypothesis 2 is partially accepted. III. Significant models of personality traits influencing the premenstrual syndromal categories are ; 1. 5 personality traits : tendency of psychoneuroses, emotional stability, dominance, activity and autonomy revealed to influence Low mood / loss of pleasure significantly. ($R^2$=.19) 2. 3 personality traits ; tendency of psychoneuroses, emotional stability and sociability revealed to influence Lability significantly. ($R^2$=.15) 3. 5 personality traits ; tendency of psychoneuroses, activity, emotional stability, sociability and achievement revealed to influence Anxiety significantly.($R^2$=.18) 4. 3 personality traits : tendency of psychoneuroses, emotional stability and sociability revealed to influence Miscellaneous mood / behavior changes significantly.($R^2$=.18) 5. 3 personality traits : tendency of psychoneuroses, psychoses and reflectiveness revealed to influence Hysteroid features significantly.($R^2$=.16) IV. No significant correlation between irregularity of menstruation and premenstrual syndrome was revealed. No significant difference between group of dysmenorrhea and group of non-dysmenorrhea in premenstrual syndrome was revealed.

  • PDF

Research on the Self-Esteem, Resilience, and Quality of life of Hemodialysis Patient (혈액투석 환자의 자아존중감, 극복력 및 삶의 질에 관한 연구)

  • Song, Chung-Sook;Jung, Sun-Young
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.11
    • /
    • pp.77-86
    • /
    • 2020
  • The research was to identify difference of values of the self-esteem, resilience and quality of life of hemodialysis patients. The survey was conducted to collect data between February 1 and 28 of 2020. SPSS/WIN 20 program was used to perform descriptive, correlation, and multiple regression analyses. In the correlation analysis, Cohabitation form(r=.262, p<.01), Economic status(r=.278, p<.01), Current health status recognition(r=.294, p<.01), Self-esteem(r=.547, p<.01), Resilience(r=637, p<.01) turned out to be influential factor for self-esteem, resilience, and quality of life according to general and disease of characteristics. Therefore, on the basis of this research, it is meaningful to provide basic data for the development of nursing interventions that allow one to embrace one's health condition and find the meaning of life in order to improve the quality of life of hemodialysis patients.

Factors influencing related health promoting behavior in College Women (여대생의 건강증진행위와 관련요인에 관한 연구)

  • Park, Hye-Sook
    • Korean Parent-Child Health Journal
    • /
    • v.4 no.2
    • /
    • pp.16-31
    • /
    • 2002
  • This study was done in order to analyze the relationship of gender identity, self-esteem, self-efficacy, hardiness, and health promotion behavior in the College Women. The subjects were 275 students from a college in Kyungbuk. The instruments used for this study were made of general characteristics(6 items), gender identity(1 item), self-esteem(10 item), self-efficacy(13 items), hardiness(38 items) and health promoting behaviors(40 items). The data were analyzed by SPSS/$PC^+$ program using descriptive statistics, Pearson's Correlation Coefficient and Multiple Stepwise Regression. The results of this study were as follows. 1. The Mean score of gender identity, self-esteem, self-efficacy, hardiness, and health promotion behavior were as follows. 1) The mean score of the health promoting behavior was 2.24. Among the subcategories, the highest score was interpersonal support(2.91), self-actualization (2.85), and the lowest score was health responsibility(1.62). 2) The mean score of the gender identity was 2.04. 3) The mean score of the self-esteem was 2.85. 4) The mean score of the self-efficacy was 6.50. 5) The mean score of the hardiness was 2.83. 2. Correlations of gender identity, self-esteem, self-efficacy, hardiness, and health promotion behavior were as follows. 1) Gender identity was positively correlated with self-esteem(r=-.287, p=.0000), self-efficacy(r=-.226, p=.0000), hardiness(r=.237, p=.0000), health promotion behavior(r=-.236, p=.0000). 2) Self-esteem was positively correlated with self-efficacy(r=.499, p=.0000), hardiness (r=-.275, p=.0000), health promotion behavior(r=.428, p=0000). 3) Self-efficacy was positively correlated with hardiness(r=-.423, p=.0000), health promotion behavior(r=.492, p=.0000). 4) Hardiness was positively correlated with health promotion behavior(r=-.457, p=.0000). 4. Self-efficacy, hardiness and self-esteem were the major predictors for health promoting behavior(35.7%).

  • PDF

miR-101-3p/Rap1b signal pathway plays a key role in osteoclast differentiation after treatment with bisphosphonates

  • Li, Jie;Li, You;Wang, Shengjie;Che, Hui;Wu, Jun;Ren, Yongxin
    • BMB Reports
    • /
    • v.52 no.9
    • /
    • pp.572-576
    • /
    • 2019
  • Bisphosphonates are the mainstay of therapy worldwide for osteoporosis. However, bisphosphonates also have limitations. The objective of this study was to determine the role of miR-101-3p/Rap1b signal pathway in osteoclast differentiation after treatment with bisphosphonates. Our results revealed that miR-101-3p was an important regulator in bisphosphonates treated-osteoclasts. When miR-101-3p was down-regulated in bone marrow-derived macrophage-like cells (BMMs), the development of mature osteoclasts was promoted, and vice versa. However, alendronate decreased multinucleated cell number regardless of whether miR-101-3p was knocked down or over-expressed. TRAP activity assay confirmed the above results. Luciferase assay indicated that miR-101-3p was a negative regulator of Rap1b. Western blot analysis revealed that protein expression level of Rap1b in BMMs transfected with OV-miR-101-3p was lower than that in BMMs transfected with an empty vector. Rap1b overexpression increased TRAP-positive multinucleated cells, while Rap1b inhibition decreased the cell numbers. In vivo data showed that miR-101-3p inhibited osteoclast differentiation in ovariectomized mice while overexpressed of Rap1b blocked the differentiation. Taken together, our data demonstrate that miR-101-3p/Rap1b signal pathway plays a key role in osteoclast differentiation after treatment with bisphosphonates.

Effect of the application of low-frequency rTMS on cognitive function in chronic stroke patients (저빈도 rTMS의 적용이 만성 뇌졸중환자의 인지기능에 미치는 영향)

  • Lee, Dong-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.12
    • /
    • pp.7239-7247
    • /
    • 2014
  • This study repeated low-frequency transcranial magnetic stimulation (rTMS) to evaluate the effects on cognitive function in chronic stroke patients. Among the chronic stroke patients, 30 patients selected by MMSE-K and BCRS-K were divided randomly into 3 groups. Group I (n=10) had only sound applied, group II (n=10) were applied 1 Hz rTMS on the damaged side and group III (n=10) were applied to 1 Hz rTMS on the opposite side for total 2 weeks, 20 minutes per a day, five times per a week. To examine the change in cognitive function, CREAD-K scores were measured before, 1 week, 2 weeks, and then 3 months after the intervention. The CREAD-K scores were measured before and 1 week, 2 weeks and 3 months after the interventions. The immediate recall memory showed a significant difference after 2 weeks and 3 months in groups II and III (p<.05), The recognition memory showed a significant difference after 2 weeks and 3 months in group III (p<.05). The delayed recall memory showed significant differences after 3 months in group III than in group I (p<.05). Therefore, the application of low-frequency rTMS has a positive influence on the cognitive rehabilitation of chronic stroke patients.