• Reproductive and Developmental Biology
• /
• 제33권3호
• /
• pp.119-123
• /
• 2009

The two dimensional quantitative structure-activity relationships (2D-QSARs) models concerning the binding affinity constants ($p[Od.]_{50}$) between 2-cyclohexyltetrahydropyrane and 2-cyclohexyltetrahydrofurane analogues as substrates, and bovine odorant binding protein (bOBP) as receptor were derived by multiple regression analyses method and discussed. The statistical quality of the optimized 2D-QSAR model (5) was good (r=0.907). From the model, the binding affinity constants ($p[Od.]_{50}$) were dependent upon the optimal value ($(TL)_{opt.}$=2.737) of total lipole (TL) of substrate molecules. Based on these findings, the high active compounds predicted by optimized 2D-QSAR model (5) were 2-(dimethylcyclohexyl)tetrahydropyrane molecule and their isomer molecules. The binding affinity constants regarding bOBP of the tetrahydrofuryl-2-yl family compounds were dependent upon the hydrophobicity (logP) of whole substrate molecules. In any case of porcine odorant-binding proteins (pOBP), the constants were dependent upon the hydrophobicity (${\pi}x={\log}P_X-{\log}P_H$) of substituents (R) in substrate molecules. Also, from the optimal values of hydrophobic constant, the hydrophobicity for bOBP influenced ca. twice time bigger (bOBP>pOBP) than that for pOBP.

• KSBB Journal
• /
• 제7권2호
• /
• pp.149-153
• /
• 1992

버섯 갈변병 유발세균인 P. tolaasii에 길항성을 나타내는 P. fluorescens를 분리하였으며, 대량배양을 위하여 최적 배지조성 및 배양의 최적조건을 확립하였다. 세포성장에 있어서 carbon및 energy source인 glucose의 경우 30g/L일 때 세포농도가 가장 높았으며, yeast extract의 농도가 10g/L까지 증가함에 따라 세포농도도 증가하였다. 질소원인 $NH_4Cl$과 $(NH_4)_2SO_4$는 각각 1.0g/L와 0.1g/L일 때 세포성장이 가장 좋게 나타났고, sulfur source인 $MgSO_4{\cdot}7H_2O$의 최적농도는 1.0g/L였다. 그리고 $KH_2PO_4$와 $CaCl_2$는 각각 1.0g/L와 0.1g/L일 때 세포농도가 가장 좋았고 온도 $30^{\circ}C$, pH6.0그리고 초기 D.O를 68로 유지시켰을 때 세포성장이 가장 높았으며, 균체 비증식속도($\mu$)와 생산성도 높았다.

• 한국식품저장유통학회지
• /
• 제10권1호
• /
• pp.47-53
• /
• 2003

후지 사과의 품질분포 조사를 위하여 재배면적 기준으로 5지역(청송, 예천, 봉화, 상주, 예산)을 선정하여 이 지역으로 부터 생산된 후지 사과를 3년간 수집하여 외적, 내적 품질인자를 분석하였다. 후지 사과의 적색도 평균치는 88.94%이었고 년도별로는 3차년도가 93.88%로 가장 높은 값을 보였다. 세로 크기는 평균 76.76mm 이고 가로 크기는 평균 87.17mm 이었으며 중량은 평균 276.749 이었다. 사과의 외관상 손상정도는 각각 평균 1.27점과 1.21점으로 물리적 손상이 병충해에 의한 손상보다 다소 많았다. 사과 품질에 있어서 가장 중요한 당도는 3년 평균치가 14.81$^{\circ}$Brix 이었고 편차는1.78$^{\circ}$Brix 이었다. 경도는 3년 평균값이 0.80kgf 이었고 pH는 3.98이었으며, 산도는 0.32%로 년도별로 차이가 크지 않았다 산지별로는 지역A의 적색도가 91.10%로 가장 높았고 지역D는 86.15%로 가장 낮았다. 크기는 종의 경우 지역B가 77.43mm로 가장 크고 지역A가 76.35mm로 가장 작았으며 횡의 크기는 지역C가 88.12mm로 가장 크고 지역D가 86.40mm로 가장 작았다. 중량은 지역B가 280.49g으로 최고치를, 지역D는 273.89g로 최저치를 보였다. 물리적 흠과 병충해에 의한 홈 또한 산지별로 차이는 있었으나 그 차이는 매우 작았다. 당도는 지역I가 15.32$^{\circ}$Brix로 가장 높았고 지역B가 14.58$^{\circ}$Brix로 가장 낮았다. 경도는 지역D와 E가 0.83kgf로 가장 단단한 것으로 나타났으며 지역C는 0.76kgf로 비교적 경도가 낮는 것으로 나타났다. pH는 지역A와 D가 4.01로 가장 높고 지역C가 3.88로 가장 낮았으며, 산도는 지역 A, C, E가 모두 0.33%로 가장 높았고 지역D가 0.31%로 가장 낮았으나 지역 간의 차이가 매우 작은 것으로 나타났다.

• 한국산업보건학회지
• /
• 제15권2호
• /
• pp.135-143
• /
• 2005

This study was conducted to measure the exposure levels to noise for the middle and the high school students who worn headsets in the PC rooms. The noise levels from the headsets were measured with noise dosimeters, and the statistical relationships between the utilization pattern, user's views on the PC rooms and it's environment were analyzed for the selected PC rooms in the Ahnshan area. The results were as follows; 1. No significant difference was found in the number of uses and average time spent per day by education level and by sex of the users(p>0.05). 2. No statistical significant difference was found between the contents selected by education level of the users (p>0.05). The male participants overwhelmingly enjoyed the PC games (98.3 %) while females selected for listening music (75.0 %) with significant difference(P<0.05), followed by browsing internet and PC communications (70.0 %), PC game (66.7 %) and chatting (33.3 %). 3. The actual noise measurements of the headsets worn by the users of different sexes and educational backgrounds produced no differences(p>0.05), while a significant difference was found between genders (p<0.05). 4. For sound pressure level measurements, the weighted average(Lavg) of 84.5 dB(A) on the left headsets exceeded that of 79.8 dB(A) on the right headsets significantly(p<0.01) and the maximum value of 96.9 dB(A) on the left headsets exceeded the maximum value of 93.5 dB(A) on the right headsets(p<0.01). 5. The actual noise measurements of the headsets worn by the users of different sexes and educational backgrounds produced no differences(p>0.05), however, the contents selected by the users with different educational backgrounds were noted with significant difference(p<0.05) while no difference was found by gender(p>0.05).

• 한국임상수의학회지
• /
• 제19권3호
• /
• pp.342-349
• /
• 2002

Vitamin D is one of important factors involved in the regulation of bone metabolism. In osteoporosis, the therapeutic effect of vitamin D on the healing process has still been controversial. To conform the effect of $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ on osteoporosis, the change of serum calcium, serum phosphorus, serum alkaline phosphatase, bone mineral density and bone mineral content of osteoporotic tibia were examined comparatively in normal control group(positive control), CFA control(negative control), CFA+$1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.01 ug/kg group and CFA+$1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.1 ug/kg group after osteoporosis was induced by single injection of complete Freund's adjuvant(CFA) in rats. In change of serum calcium. the significantly increased value was shown on 2nd and 5th week(P< 0.05) after treatment in $1{\alpha}$, 25 dihydroxy-vitamin D$_3$ 0.01 ug/kg group and on 3rd week(P<0.05) after treatment in $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.1 ug/kg group than CFA control. In change of serum phosphorus, the significantly increased value was shown on 2nd week(P<0.05) after treatment in $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.01 ug/kg group and on 3rd and 4th week(P<0.05) after treatment in $1{\alpha}$, ,25 dihydroxy-vitamin $D_3$ 0.1 ug/kg group than CFA control. The value of bone mineral density and bone mineral content of tibia was increased in both $1{\alpha}$,25 dihydroxy-vitamin $D_3$ 0.01 ug/kg group and $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.1 ug/kg group than CFA control, and the increase rate of that was higher in $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.1 ug/kg group than $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ 0.01 ug/kg group. Considering above findings collectively, it was considered that $1{\alpha}$, 25 dihydroxy-vitamin $D_3$ was effective in preventing the complete Freund's adjuvant-induced osteoporotic decrease of bone mass.

• 한국식품과학회지
• /
• 제45권4호
• /
• pp.526-529
• /
• 2013

이 연구는 $15^{\circ}C$에서 10시간동안 pH 5 환경과 461-nm LED를 조사하였을 때 S. aurues (MRSA 포함), E. coli (E.coli O157:H7 포함)의 살균 효과를 측정하고자 수행하게 되었다. 461-nm LED만을 10시간동안 조사하였을 때. S. aureus (MRSA 포함)은 4 log CFU/mL 감소하였다. 그리고 E. coli (E. coli O157:H7 포함)는 9시간동안 조사하였을 때 불활성화되었다. 그러나 pH 5와 461-nm LED를 함께 조사한 결과, 모든 균주들은 7시간동안 조사하였을 때 불활성화되었다. 이 가시광선 불활성화 결과는 외인성의 광감각제없이 이루어 졌다. 461-nm LED만을 조사하였을 때, 가장 높은 D값은 S. aureus (ATCC 27664)으로 5.05시간이었으며 가장 낮은 D값은 E. coli O157: H7 (ATCC 35150)으로 1.39시간이었다. pH 5와 461-nm LED를 함께 조사한 결과, 가장 높은 D값은 S. aureus (ATCC 19095)의 1.58시간이었으며, 가장 낮은 D값은 S. aureus (ATCC 27664)의 0.83시간이었다. 본 연구 결과는 pH 5와 461-nm LED를 함께 조사한 것이 461 nm LED 한가지 환경보다 살균효과가 증가되었다는 것을 보여준다.

• 방사성폐기물학회지
• /
• 제20권2호
• /
• pp.151-160
• /
• 2022

The sorption of Eu on MX-80 bentonite in Na-Ca-Cl solutions is investigated at a molal proton concentration (pH_m) range of 3 to 10 and an ionic strength (I) range of 0.1 to 6 m (mol·kgw^-1). The sorption equilibrium of Eu on MX-80 is achieved within 14 to 21 d at I = 0.1 and 6 m. The sorption distribution coefficient (K_d) values of Eu for MX-80 increase as pH_m increases from 3 to 6 for all I values, and they are independent of pH_m between 8 and 10 at I ≥ 0.5 m. Meanwhile, at I = 0.1 m, the K_d value at pH_m = 10 is slightly lower than those at pH_m = 8 and 9. The K_d values are not affected by the I values between 0.5 m and 6 m, whereas the K_d value at I = 0.1 m is greater than those at I ≥ 0.5 m, except at pH_m = 10. A two-site protolysis nonelectrostatic surface complexation and cation exchange sorption model is applied to the Eu sorption data for I ≤ 4 m, and the equilibrium constants of the sorption reactions are estimated.

• The Korean Journal of Ecology
• /
• 제25권1호
• /
• pp.51-58
• /
• 2002

An investigation of occurrence and distribution of dictyostelid cellular slime molds in South Korea were carried out. Thirty-one dictyostelid cellular slime molds were isolated from soils of 256 sample sites of 41 area within mountain forests, riversides, streamsides and coastal area in South Korea. The average number of species isolated at a given study area was 6.85. Based on the distribution value calculated from average frequency and site presence, four dictyostelid species distributed widely in South Korea; Polyspondylium pallidum, P violaceum, Dictyostellium mucoroides and D. minutum. Especially, P pallidum. were found in 30 area and the highest site presence. Eight dictyostelid species was described firstly in this study: D areum var. luteolum, D. delicatum, D. deminutivum, D. implicatum, D. microsporum, D. mucoroides var. stoloniferum, D septentrionalis, and P. candidum.

• Asian-Australasian Journal of Animal Sciences
• /
• 제27권7호
• /
• pp.996-1002
• /
• 2014

An experiment was conducted to evaluate the effects of dietary alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) on growth performance, carcass characteristics and meat quality in Arbor Acres broilers. A total of 486 1-d-old male Arbor Acres broilers were randomly allocated to 9 dietary treatments, 9 treatments were group A (0 mg/kg LA and 0 mg/kg ALC), group B (50 mg/kg LA and 0 mg/kg ALC), group C (100 mg/kg LA and 0 mg/kg ALC), group D (0 mg/kg LA and 50 mg/kg ALC), group E (50 mg/kg LA and 50 mg/kg ALC), group F (100 mg/kg LA and 50 mg/kg ALC), group G (0 mg/kg LA and 100 mg/kg ALC), group H (50 mg/kg LA and 100 mg/kg ALC), group I (100 mg/kg LA and 100 mg/kg ALC). Birds were slaughtered at 42 days old. Average daily gain (ADG), average feed intake (AFI), feed conversion rate (FCR), eviscerated rate, breast muscle percentage, thigh muscle percentage, abdominal fat percentage, liver weight, muscle color ($L^*$ value, $a^*$ value, $b^*$ value), pH values at 45 min and 24 h postmortem were measured. Results showed that there existed an interaction between LA and ALC in growth performance of broilers, carcass traits and meat quality. The overall result is that high level of LA and ALC led to lower AFI, ADG (p<0.01), lower abdominal fat percentage, liver weight (p<0.01), lower $L^*$ value, $a^*$ value, and $b^*$ value of breast muscle, $L^*$ value of thigh muscle (p<0.05), and higher FCR (p<0.01), eviscerated rate (p<0.01), breast muscle percentage, thigh muscle percentage (p<0.05), $a^*$ value, pH 45 min and pH 24 h of thigh muscle (p<0.01). These results suggested that dietary LA and ALC contributed to the improvement of meat quality in broilers.

• Asian-Australasian Journal of Animal Sciences
• /
• 제2권3호
• /
• pp.418-420
• /
• 1989