• Journal of the Korean earth science society
• /
• v.23 no.8
• /
• pp.683-696
• /
• 2002

In this work. we investigated the ozone data sets that exceeded ambient air quality standards from 31 air quality monitoring stations dispersed across the Seoul metropolitan city during the period covering 1990 and 2000. To specifically describe spatial dependency of high level O$_3$ occurrence, we grouped our data into four different geographical ozone exceedance is much longer in SW than the other three sectors. When we compared the exceedance data in terms of occurrence frequency, the month of maximum frequency differed slightly among different sectors. Examination of long-term exceedance trend indicated that its frequency increased continuously from all sectors over the past years, although slightly opposite patterns existed in their absolute values. Most importantly, its peak occurrence frequency seemed to center in very recent years such as 1998 (NE sector) and 2000 (ail pattern sectors except NE). Consequently, we were able to describe the existence of certain patterns of ozone exceedance data sets in terms of both temporal and spatial scales.

• Journal of the Korea Institute of Building Construction
• /
• v.19 no.6
• /
• pp.539-547
• /
• 2019

Recently, the international community signed a climate change agreement to prevent global warming. Yet currently, the fossil fuels have been widely used in to supply building energy for cooling and heating. The Green Building certification (G-SEED), an energy efficiency rating for new or existing buildings requires that buildings meet certain conditions. Insulation is used as a building material to reduce the energy supply to buildings and to improve the thermal insulation, and it accounts for more than 90% of the total heat resistance provided by the building surface components that meet the energy-saving design standards of new buildings. In this investigation, a performance evaluation study was conducted through an experimental study by directly extracting the foam polystyrene insulation on-site during the remodeling of a building that was in the range of 22~38 years old. Through tests, it was found that the thermal conductivity of the extrusion method insulation (XPS) was reduced by 48% and the compressive strength of XPS decreased by 36% compared to KS M 3808, which is the initial quality standard. For bead method insulation (EPS) with a thickness of 50mm, the thermal conductivity, the compressive strength, and flexural failure load were similar to the initial quality standard. Therefore, in the calculation of the primary energy requirement per unit area per year, the performance of bead method insulation can be estimated simply by considering the thickness of the insulation, while a correction factor that considers its performance deterioration should be applied when extrusion method insulation is used.

• The Journal of the Korean bone and joint tumor society
• /
• v.17 no.1
• /
• pp.30-35
• /
• 2011

Purpose: This study was designed to evaluate the treatment results of malignant melanoma and to analyze the factors influencing prognosis. Materials and Methods: Thirty one cases of malignant melanoma were included in this study. They were treated in our hospital surgically, medically and immunologically from January 1996 to December 2005, and were followed more than 5 years. We compared 5 year survival rate (5YSR) according to the age, gender, anatomical site, depth of tumor, TNM stage, involvement of lymph node and immuno-chemotherapy. Results: Overall 5YSR was 80.6%. 5YSR of the age group below 65 years was 89.7% and 66.7% for the age group over 65 (p=0.033). 5YSR for men was 75% and 90.9% for women. 5YSR according to the site of occurrence showed 66.7% in upper extremities, 89.5% in lower extremities, and 66.7% in other site. 5YSR was 100% for the Clark level below III and 62.5% for the level above IV (p=0.032). 5YSR was 53.8% for lymph node metastasis group and 100% for non-lymph node metastasis group (p=0.021). Conclusion: We concluded that early diagnosis and wide excision was the most important in treatment of malignant melanoma. The prognostic fractors of malignant melanoma were age, depth of tumor (Clark's stage) and metastasis of lymph node.

• Journal of Pharmaceutical Investigation
• /
• v.31 no.2
• /
• pp.125-130
• /
• 2001

Bucillamine is a novel cysteine derivative with two free intramolecular sulfhydryl groups, and has a preventive and therapeutic effect on adjuvant arthritis, suggesting its antirheumatic action. With respect to the effect on the immune system, bucillamine-exerted such immunoregulating actions are to nomalize an excessive reduction or acceleration in immune reaction. It is useful not only in patients with early stage of rheumatoid arthritis (RA) but also in those with active RA retained for more than 10 years. The purpose of the present study was to evaluate the bioequivalence of two bucillamine tablets, $Rimatil^{TM}$ (Chong Kun Dang Pharmaceutical Co., Ltd.) and $Bucilin^{TM}$ (Kuhn Il Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Eighteen normal male volunteers, $23.67{\pm}2.09$ years in age and $65.03{\pm}6.73\;kg$ in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After three tablets containing 100 mg of bucillamine per tablet were orally administered, blood was taken at predetermined time intervals and the concentrations of bucillamine in serum were determined using GC/MS with mass selective detector. Pharmacokinetic parameters such as $AUC_t$, $C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in $AUC_t$, $C_{max}\;and\;T_{max}$ between two tablets were -0.29%, -3.20% and 8.22%, respectively, when calculated against the $Rimatil^{TM}$ tablet. The powers $(1-{\beta})$ for $AUC_t\;and\;C_{max}$ were 84.31 % and 91.16%, respectively. Minimum detectable differences $({\Delta})$ at ${\alpha}=0.10$ and $1-{\beta}=0.8$ were less than 20% (e.g., 18.58% and 16.51% for $AUC_t\;and\;C_{max}$, respectively). The 90% confidence intervals were within ${\pm}20%$ (e.g.,$-12.77{\sim}12.20$ for $AUC_t$ and $-14.30{\sim}7.90$ for $C_{max}$). Two parameters met the criteria of KFDA for bioequivalence, indicating that $Bucilin^{TM}$ tablet is bioequivalent to $Rimatil^{TM}$ tablet.

• Clinics in Shoulder and Elbow
• /
• v.13 no.2
• /
• pp.181-187
• /
• 2010

Purpose: To determine clinical results for arthroscopic repair of a full-thickness rotator cuff tear using a suture bridge technique. Materials and Methods: Between November, 2007 and October, 2008, we evaluated 90 cases of arthroscopic middle, large rotator tear cuff repair. The mean follow-up period was 15 months (range, 12-23 months). Forty-three cases had medium-sized tears; 47 cases had large-sized tears. At the preoperative stage and again at last follow-up, functional results were assessed by the KSS, ASES, UCLA and the PVAS (Pain visual analogue score). Results: Pain score improved from 2.56 preoperatively to 0.96 at final follow-up; movement scores improved from 6.94 to 1.70. At. final follow-up, the average UCLA score improved from 17.08 to 31.17 with 31 excellent (34%), 49 good (54%) and 10 poor results (12%). The final UCLA score was 31.47 in the group less than 60 years of age and 30.69 in the group over 61 years of age (p=0.344). The UCLA score was 31.23 in those with medium-sized tears and 31.11 in those with large-sized tears (p=0.924). The UCLA score was 31.10 in non-trauma patients and 31.23 in trauma patients (p=0.929). Conclusion: Arthroscopic repair of a full-thickness rotator cuff tear using a suture bridge technique can produce excellent clinical results. These outcomes are not affected by age or trauma history.

• Clinics in Shoulder and Elbow
• /
• v.8 no.2
• /
• pp.97-104
• /
• 2005

Purpose: To report the results of surgical treatment of comminuted fractures of distal humerus and to identify factors that affect the results. Materials and Methods: Thirty-two patients who were treated with open reduction and internal fixation for comminuted fracture of distal humerus were enrolled. According to the AO classification, A2.3 was 1 case, A3.2, 2 cases, A3.3, 8 cases, B1.3, 1 case, B2.3, 1 case, C2.2, 5 cases, C2.3, 4 cases, C3.2, 3 cases and C3.3, 7 cases. As fixation technique, 17 cases were fixed by double plates, 4 cases by only K-wires, 4 cases by only screws, 3 cases by K-wires and screws and 4 cases by one plate and screws. The mean age at the time of the operation was 49 years(range, $19{\sim}77$ years). The mean follow-up period was 16 months(range, $8{\sim}51$ months). Results: At the last follow-up, the mean maximum flexion was $116.4^{\circ}\;(range,\;85{\sim}140^{\circ})$ and the mean loss of terminal extension was $11.8^{\circ}\;(range,\;0{\sim}40^{\circ})$. The average Mayo elbow performance score was $91.4^{\circ}\;(range,\;55{\sim}100^{\circ})$. Overall 29 cases(91%) showed good to excellent results. The mean range of motion of extraarticular and intraarticular fracture group was $105.5^{\circ}\;(range,\;65{\sim}140^{\circ})$ and $104^{\circ}\;(range,\;55{\sim}140^{\circ})$, respectively. The average elbow score of both groups was$93^{\circ}\;(range,\;70{\sim}100^{\circ})$ and $90.7^{\circ}\;(range,\;55{\sim}100^{\circ})$. Over 90% showed more than good results. 30 cases(94%) showed complete bony union but two cases, nonunion. One case of the nonunion cases underwent replating with bone graft as revision surgery and total elbow arthroplasty was performed in the other case. At the last follow-up, 27 patients(84.4%) showed subjective satisfaction. Conclusion: Open reduction and internal fixation with appropriate surgical technique for comminuted fractures of distal humerus showed good results, which were not affected by age at the time of operation, fixation methods and anterior transposition of the ulnar nerve. Transolecranon approach may be considered as good choice for intraarticular comminuted fractures of distal humerus.

• Korean Journal of Ichthyology
• /
• v.12 no.2
• /
• pp.101-110
• /
• 2000

Population ecology of Rhynchocypris keumgangensis have been investigated at upper part of the Han River in Korea from January to December, 1995. The habitat was low water temperature and clean area, and stream form was Aa. The major cohabitation fish was Phoxinus phoxinus. The total lengths in this population indicated that below 40 mm group is one year old, 40~65 mm group is two years old, 65~80 mm group is three year and the 80 mm longer group is regarded over four years old. There were no differences in total length distribution between the female and the male. The males became sexually mature, when longer than 45 mm and females longer than 65 mm in total length. Spawning season was from April to mid May with the water temperature in $11{\sim}14^{\circ}C$ and the properous period was April. The mean number of eggs in ovary was 1,616. The sex ratio all the year round of the female to the male was 1 : 0.75. The current velocity of the spawning ground was 44 (20~80) cm/sec and water depth was 35 (5~70) cm. Eggs were laied in 5~15 cm deep underneath the immaculate pebbles (2~6 cm). Sex ratio of the female to the male was 1 : 6.90 for spawning behavior.

• Korean Journal of Soil Science and Fertilizer
• /
• v.40 no.6
• /
• pp.482-487
• /
• 2007

This study was conducted to investigate the effect of long-term continuous application of fertilizers for rice cultivation. Changes of physical and chemical properties of paddy soil and the rice yield by continuous application of NPK fertilizers, ammonium sulphate, and urea over fifty years, from 1954 to 2003, were investigated. The rice yield index of each treatment were 100 of NPK plots, 84 of ammonium sulphate plots, 81 of urea plots, and 62 of no fertilizer plots. The variance of yield was large according to the quality of irrigation water. Nutrient uptakes by rice plants in ammonium sulphate and urea plots were significantly smaller than those in NPK plots; 86 and 75% in T-N, 79 and 82% in $P_2O_5$, 64 and 58% in $K_2O$, and 94 and 90% in $SiO_2$, respectively. Bulk density of soil in NPK plots significantly decreased compared to those in no fertilizer, ammonium sulphate, and urea plots, whereas CEC in NPK plots increased compared to other plots. Soil pHs of all plots were higher than that before experiment which was 5.2; 6.0 in no fertilizer, 5.9 in urea and NPK, and 5.4 in ammonium sulphate plots. The available phosphate in soil increased by $2.5mg\;kg^{-1}\;yr^{-1}$ when $70kg\;ha^{-1}$ of P fertilizer applied for rice cultivation, and decreased by $1.8mg\;kg^{-1}\;yr^{-1}$ when no P fertilizer applied.

• Biomedical Science Letters
• /
• v.2 no.2
• /
• pp.187-198
• /
• 1996

The cut-off values and related factors for total cholesterol of serum in normal Korean adults were studied from March to October, 1995, based on the data of 1,818 healthy adults of human involved the male and female. The comparisons of the serum total cholesterol levels were analyzed by sex, age, systolic blood pressure, diastolic blood pressure, body weight, height, PIBW, BMI and other biochemical tests. 1. The serum total cholesterol level were 194.4 mg/dl in total group, 186.9 mg/dl for male, and 197.6 mg/dl for female. 2. There was no significant differences by sex among the 21 to 50 ages group, but significantly higher in women than in men over 51 years old. 3. In general, the levels of serum total cholesterol were increased with age, the highest level in men was 192.7 mg/ dl in 51 to 60 years old, and 210.5 mg/dl in more than 60 years old in women. 4. The cut-off values of serum total cholesterol for moderate risk were 191 mg/dl in 21 to 30 years group, 195 mg/dl in 31 to 40 years,214 mg/dl in 41 to 50 years, 227 mg/dl in 51 to 60 years, and 222 mg/dl in more than 61 years. The cut-off values of serum total cholesterol for high risk were 214 mg/dl dl in 21 to 30 years group, 214 mg/dll in 31 to 40 years, 239 mg/dl in 41 to 50 years, 213 mg/dl in 51 to 60 years, and 248 mg/dl in more than 61 years. 5. The mean values of serum total cholesterol were showed positive correlation with age, PIBW, BMI, systolic blood pressure and diastolic blood pressure. 6. Serum total cholesterol level of drinking group(188.9$\pm$34.85mg/dl) was showed love. than those of non-drinking group(196.0$\pm$36.0 mg/dl). 7. Serum total cholesterol levels of regular excercise group(192.1$\pm$33.3 mg/dl) was significantly lower than those of non regular excercise group(195.8$\pm$37.0 mg/dl).

• Journal of agricultural medicine and community health
• /
• v.23 no.1
• /
• pp.65-78
• /
• 1998

This study was conducted to find out the factors which have an effect on the rural aged's natural history by disability in Activities of Daily Living(ADL) and ADL decline with 475 old people which were chosen except the dead 90 and unconfirmable 56 old people by performing follow-up survey for 4 years since 1993 on the basis of presurveyed data about 621 home old people over 60 years residing in 13 villages at Kangdong-myon, Kyongju-city, Kyongsangbuk-do Province, Korea. Such activities of daily living as bathing, dressing, going to toilet, transfer, feeding and continence were examined. 1. In the follow-up survey for 4 years, the ADL distribution of the dead was remarkably lower than the subject group. 2. It was also shown in the 4-year follow-up survey that 82.1% of high ADL group maintained high ADL while 77.8% of low ADL group died within 4 years. 3. The occurrence percentage of disabilities of each group by ADL item for 4 years appeared high in such an order as bathing, continence, dressing, going to toilet, transfer and feeding. 6.7%(8.1% for female and 4.6% for male) of the old people who were the high ADL group at the time of the first survey had disabilities that occurred after 4 years. 4. In the change of ADL according to general characteristics used to analyse the factors which have an effect on ADL decline, there was a significant difference in age and job, that is, the jobless old people had the higher degree of ADL decline. In the change of ADL according to behavioral pattern, for the male old people there was a significant difference in support of living expenses and subjective health condition. In this case, the degree of ADL decline was higher if they depended on their sons & daughters or spouses and felt that they were not healthy.