• 한방안이비인후피부과학회지
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• 제34권2호
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• pp.53-69
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• 2021

Objectives : The purpose of this study is to analyze the effects of treatment between Western medicine and Korean medicine on Allergic rhinitis patients using national population-based claim data from the Health Insurance Review and Assessment Service. Methods : The subjects of the study were 30,024 patients in the Korean medicine group and 30,024 in the Western medicine group who were diagnosed with Allergic rhinitis from September 1, 2018 to December 31, 2018. Propensity score analysis was used for matching age, sex, etc. at a ratio of 1:1. Cox regression and subgroup analysis were used to estimate the adjusted hazard ratio of recurrence, Asthma, and Atopic dermatitis in Korean medicine group and Western medicine group. In addition, the total treatment period, total treatment cost, and average cost per day of visit were compared and analyzed. Results : Compared to Korean medicine, Western medicine had a significantly higher risk of recurrence at 1.701 times, Asthma occurrence risk at 1.609 times and Atopic dermatitis occurrence risk at 1.098 times. Compared to Western medicine, the total treatment period of Korean medicine was 14.27 days longer, the total treatment cost was 53,591 won more, and the average cost per day was 7,539 won more. Conclusions : This study is a retrospective cohort study using the propensity score matching in Korea to compare the outcomes of Allergic rhinitis between Western medicine and Korean medicine. Further research is needed by considering patients characteristics, and linking with additional data.

• Journal of Gastric Cancer
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• 제21권2호
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• pp.155-168
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• 2021

Purpose: Previous studies have demonstrated the usefulness of the controlling nutritional status (CONUT) score in nutritional assessment and survival prediction of patients with various malignancies. However, its value in advanced gastric cancer (GC) treated with neoadjuvant chemotherapy and curative gastrectomy remains unclear. Materials and Methods: The CONUT score at different time points (pretreatment, preoperative, and postoperative) of 272 patients with advanced GC were retrospectively calculated from August 2004 to October 2015. The χ² test or Mann-Whitney U test was used to estimate the relationships between the CONUT score and clinical characteristics as well as short-term outcomes, while the Cox proportional hazard model was used to estimate long-term outcomes. Survival curves were estimated by using the Kaplan-Meier method and log-rank test. Results: The proportion of moderate or severe malnutrition among all patients was not significantly changed from pretreatment (13.5%) to pre-operation (11.7%) but increased dramatically postoperatively (47.5%). The pretreatment CONUT-high score (≥4) was significantly associated with older age (P=0.010), deeper tumor invasion (P=0.025), and lower pathological complete response rate (CONUT-high vs. CONUT-low: 1.2% vs. 6.6%, P=0.107). Pretreatment CONUT-high score patients had worse progression-free survival (P=0.032) and overall survival (OS) (P=0.026). Adjusted for pathologic node status, the pretreatment CONUT-high score was strongly associated with worse OS in pathologic node-positive patients (P=0.039). Conclusions: The pretreatment CONUT score might be a straightforward index for immune-nutritional status assessment, while being a reliable prognostic indicator in patients with advanced GC receiving neoadjuvant chemotherapy and curative gastrectomy. Moreover, lower pretreatment CONUT scores might indicate better chemotherapy responses.

• Journal of Trauma and Injury
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• 제34권1호
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• pp.3-12
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• 2021

Purpose: To evaluate the severity of trauma, many scoring systems and predictive models have been presented. The quick Sequential Organ Failure Assessment (qSOFA) is a simple scoring system based on vital signs, and we expect it to be easier to apply to trauma patients than other trauma assessment tools. Methods: This study was a cross-sectional study of trauma patients who visited the emergency department of Jeju National University Hospital. We excluded patients under the age of 18 years and unknown outcomes. We calculated the qSOFA, the Modified Early Warning Score (mEWS), Revised Trauma Score (RTS), and Injury Severity Score (ISS) based on patients' initial vital signs and assessments performed in the emergency department (ED). The primary outcome was mortality within 14 days of trauma. We analyzed qSOFA scores using multivariate logistic regression analysis and compared the predictive accuracy of these scoring systems using the area under the receiver operating characteristic curve (AUROC). Results: In total, 27,764 patients were analyzed. In the multivariate logistic regression analysis of the qSOFA, the adjusted odds ratios with 95% confidence interval (CI) for mortality relative to a qSOFA score of 0 were 27.82 (13.63-56.79) for a qSOFA score of 1, 373.31 (183.47-759.57) for a qSOFA score of 2, and 494.07 (143.75-1698.15) for a qSOFA score of 3. In the receiver operating characteristic (ROC) curve analysis for the qSOFA, mEWS, ISS, and RTS in predicting the outcomes, for mortality, the AUROC for the qSOFA (AUROC [95% CI]; 0.912 [0.871-0.952]) was significantly greater than those for the ISS (0.700 [0.608-0.793]) and RTS (0.160 [0.108-0.211]). Conclusions: The qSOFA was useful for predicting the prognosis of trauma patients evaluated in the ED.

• Journal of Pharmaceutical Investigation
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• 제40권spc호
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• pp.19-31
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• 2010

Orally administrated drugs permeate the biological membrane by various transport mechanisms. The oral absorption potential is closely related to the physicochemical properties of the drug and interaction with the physiological factors surrounding the site of absorption. Assessment of the drug membrane permeability is an integral part of the early stage drug developmental process. Appropriate selection of the permeability screening method at the right stage of drug development process is important in achieving successful developmental outcomes. This review aims at introducing currently available in vitro and in vivo screening methods for the membrane permeability assessment.

• Structural Engineering and Mechanics
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• 제41권1호
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• pp.83-94
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• 2012

Assessment of a monumental concrete arch bridge with a total length of 210 meters having three major spans of 30 meters and a height of 65 meters, which is located in an earthquake-prone region in southern part of the country is presented in this study. Three-dimensional finite element model of the bridge was generated using a commercially available general finite element analysis software and based on the outcomes of a series of in-depth acceleration measurements that were conducted on-site, the model was refined. By using the structural parameters obtained from the dynamic and the static tests, calibrated model of the bridge structure was obtained and this model was used for necessary calculations regarding structural assessment and evaluation.

• Earthquakes and Structures
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• 제16권4호
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• pp.375-389
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• 2019

During earthquakes, the performance of structures needs to be evaluated, which provides guidance for selecting suitable retrofitting schemes. The purpose of this paper is to accomplish seismic assessment of a simple steel residential building. Once the responses of the system are determined, the scope of the study extends to evaluate selected retrofitting strategies that are intended to rehabilitate the flaws of the structure under prescribed ground motions with high probability of occurrence at the site. After implementing the retrofits, seismic assessment of the upgraded structure is carried out to check if the remediation at various seismic performance levels is acquired or not. Outcomes obtained from retrofitted scenarios are compared to the results obtained from the initial un-retrofitted configuration of the structure. This paper presents the process for optimal selection of rehabilitation solutions considering the cost of implementation, downtime and disruption to property owners while improving the seismic performance level of the structure.

• 한국전자통신학회논문지
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• 제11권8호
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• pp.817-826
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• 2016

생활공간에서 안전을 확보하는 것은 중요하다. 본 연구에서는 기존의 지역별 시간별 사건발생 빈도 기반의 위험 알림 서비스에서 더 확장된 위험도 산출 방안을 제안한다. 시간외에도 생활공간의 조도, 유동인구 뿐 아니라 개인의 상태까지 위험도 산출에 포함하였다. 기존의 확률기반 증거이론은 상황과 관련있는 요소의 수가 증가할 때, 계산량은 급증하는 문제가 있는데 이를 피하기 위하여 퍼지이론을 도입하여 확장성을 확보할 수 있었다. 제안한 산출 방안으로 위험도를 산출한 계산 결과가 언어적 형용 표현까지 가능함을 볼 수 있었다.

• 환경영향평가
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• 제1권1호
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• pp.41-50
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• 1992

To prevent unwanted visual impacts of proposed projects before they are actually built, Visual Impact Assessment(VIA) is conducted in current landscape planning and management process. The application of VIA to actual projects raises some important questions: "What views will the project affect?" "What tools and techniques are effective for predicting and portraying future landscape conditions?" "Who should determine the value of the impacts?" and "How can the impacts be measured?" Types and levels of visual impacts should be decided through analyzing both the existing landscape and the proposed project. Computer-based visual simulations will play a pivotal role as effective prediction and communication tools. With professionals' assistance, the public participation in the VIA process will produce meaningful solutions for planning and managing the future landscape. Also, the use of a proper response format and sensitive assessment criteria in measuring the public's opinion will enrich outcomes of the assessment. Based on the methodological framework, the case study briefly explains an application of VIA to an actual project.

• 대한원격탐사학회지
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• 제40권3호
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• pp.243-255
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• 2024

This study compares Static Terrestrial Laser Scanning (STLS)with the conventional Total Station (TS) method for the geometric assessment of cylindrical storage tanks. With the crucial need for maintaining tank integrity in the oil and gas industry, STLS and TS methods are evaluated for their efficacy in assessing tank deformations. Using STLS and TS, the roundness and verticality of two cylindrical tanks were examined. A deformation analysis based on American Petroleum Institute (API) standards was then provided. Key objectives included comparing the two methods according to API standards, evaluating the workflow for STLS point cloud processing, and presenting the pros and cons of the STLS method for tank geometric assessment. The study found that STLS, with its detailed and high-resolution data acquisition, offers a substantial advantage in having a comprehensive structural assessment over TS. However, STLS requires more processing time and prior knowledge about the data to tune certain parameters and achieve accurate assessment. The project outcomes intend to enhance industry professionals' understanding of applying STLS and TS to tank assessments, helping them choose the best method for their specific requirements.

• 한국초등과학교육학회지:초등과학교육
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• 제38권4호
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• pp.439-452
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• 2019

This study aims to compare self- and peer-assessments of science-gifted elementary students' scientific creativity. A science-gifted program on the Pascal's principle was implemented to 40 fifth-graders in the Science-Gifted Education Center for two weeks. After that, students presented their results from a scientific creativity task using the principle in class. The task was to devise a new and useful tool using the principle, and it included the students' self-assessment about their idea. During presentation, students were asked to assess the works of peers and write down the reasons that they gave the scores they gave. Shortly, student self- and peer-assessments about students' scientific creativity outcomes were compared. Based on two essential components of creativity, ideas that satisfy both originality and usefulness can be counted as scientifically creative. The main results of this study are as follows: First, the average scores of student self- and peer-assessments were 71.5 and 61.9. Second, the standard deviations of student self- and peer-assessments were 14.47 and 5.79. Third, among scientific creativity, originality, usefulness scores, only originality had a significant correlation between student self- and peer-assessment (r=.42). Fourth, the students were categorized into four groups according to the levels of their scores by student self- and peer-assessment. And the frequencies of peer-assessment group had a significant difference at p<0.05 level, according to self-assessment group (Chi Square=4.0000, df=1, p=0.0455). Fifth, through a case study by group, the results suggesting that self-assessment could be affected by the students' self-efficacy and perfectionism and such effect could also influence peer-assessment have been found. The result showed that how the student self- and peer-assessment of scientific creativity are different and what the students' thoughts on the evaluation of scientific creativity are. The findings suggested that there are several things to consider for the educators to make efforts to construct consistent assessment methods for scientific creativity.