• 융합보안논문지
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• 제10권2호
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• pp.27-35
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• 2010

임베디드 리눅스 시스템을 이용하여 OSGi 기반 원격 번들제어 서비스 및 방문자 확인을 위한 웹 카메라 제어를 통한 방문자의 신원을 확인할 수 있는 응용 시스템을 설계 및 구현하였다. 구현된 시스템은 임베디드 시스템에 리눅스와 자바를 포팅하여 오픈 Oscar 프레임워크를 설계하였고, 근거리 통신망을 통해 웹 카메라를 제어할 수 있도록 구현하였다. 또한, 구현 시스템에서 시리얼은 RFID 리더기의 데이터를 수신받아 원격지에서 웹을 통해 방문자의 정보를 확인할 수 있으며, 댁내에서는 무선으로 인터넷을 할 수 있는 시스템을 설계하였다. 본 논문에서는 기본적으로 각 장치의 관리 및 모니터링을 구현할 때 OSGi 기반의 통합된 서비스 제공을 통해 효율적인 홈네트워크 시스템 개발 및 다양한 응용 서비스의 개발 기간을 단축할 수 있음을 알 수 있었다.

• 한국전자통신학회논문지
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• 제5권1호
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• pp.74-80
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• 2010

임베디드 리눅스 시스템을 이용하여 OSGi 기반 원격 번들제어 서비스 및 방문자 확인을 위한 웹 카메라 제어를 통한 방문자의 신원을 확인할 수 있는 응용 시스템을 설계 및 구현하였다. 구현된 시스템은 임베디드 시스템에 리눅스와 자바를 포팅하여 오픈 Oscar 프레임워크를 설계하였고, 근거리 통신망을 통해 웹 카메라를 제어할 수 있도록 구현하였다. 또한, 구현 시스템에서 시리얼은 RFID 리더기의 데이터를 수신받아 원격지에서 웹을 통해 방문자의 정보를 확인할 수 있으며, 댁내에서는 무선으로 인터넷을 할 수 있는 시스템을 설계하였다. 본 논문에서는 기본적으로 각 장치의 관리 및 모니터링을 구현할 때 OSGi 기반의 통합된 서비스 제공을 통해 효율적인 홈네트워크 시스템 개발 및 다양한 응용 서비스의 개발 기간을 단축할 수 있음을 알 수 있었다.

• 한국임상수의학회지
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• 제22권2호
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• pp.160-162
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• 2005

Dead oscars (Astronotus ocellatus) were presented for necropsy in January, 2005. Oscars, which had been reared densely, were dead in large quantities. At necropsy, they were severely infected by Dactylogyrus spp. We requested for the oscar samples which had been raised in the same water tank. Two of them were sacrificed and necropsied. At the microscopic examination, we verified dactylogyrosis of oscars. The other oscars were treated by praziquantel. Treatment was started with a dosage of 2.5 mg/L. From a second day, we treated 5.0 mg/L every two days during 4 days. At sixth day, No Dactylogyrus flukes were found but only larvae were existed. After 2 weeks without additional medication, both Dactylogyrus flukes and larvae were eliminated.

• 천문학회보
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• 제44권1호
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• pp.69.3-69.3
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• 2019

The CHIMPS2 survey is to extend the JCMT HARP $^{13}CO/C^{18}O$ J=3-2 Inner Milky-Way Plane Survey (CHIMPS) and the ${12}^CO$ J=3-2 survey (COHRS) into the inner Galactic Plane, the Central Molecular Zone (CMZ), and a section of the Outer Plane. When combined with the complementary $^{12}CO/^{13}CO/C^{18}O$ J=1-0 survey at the Nobeyama 45m (FUGIN) at matching 15" resolution and sensitivity, and other current CO surveys, the results will provide a complete set of transition data with which to calculate accurate column densities, gas temperatures and turbulent Mach numbers. These will be used to: analyze molecular cloud properties across a range of Galactic environments; map the star-formation efficiency (SFE) and dense-gas mass fraction (DGMF) in molecular gas as a function of position in the Galaxy and its relation to the nature of the turbulence within molecular clouds; determine Galactic structure as traced by molecular gas and star formation; constrain cloud-formation models; study the relationship of filaments to star formation; test current models of the gas kinematics and stability in the Galactic center region and the flow of gas from the disc. It will also provide an invaluable legacy data set for JCMT that will not be superseded for several decades. In this poster, we will present the current status of the CHIMPS2.

• BMB Reports
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• 제56권10호
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• pp.551-556
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• 2023

Ginsenosides, among the most active components of ginseng, exhibit several therapeutic effects against cancer, diabetes, and other metabolic diseases. However, the molecular mechanism underlying the anti-osteoporotic activity of ginsenoside Rg2, a major ginsenoside, has not been clearly elucidated. This study aimed to determine the effects of ginsenoside Rg2 on receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation. Results indicate that ginsenoside Rg2 inhibits RANKL-induced osteoclast differentiation of bone marrow macrophages (BMMs) without cytotoxicity. Pretreatment with ginsenoside Rg2 significantly reduced the RANKL-induced gene expression of c-fos and nuclear factor of activated T-cells (Nfatc1), as well as osteoclast-specific markers tartrate-resistant acid phosphatase (TRAP, Acp5) and osteoclast-associated receptor (Oscar). Moreover, RANKL-induced phosphorylation of mitogen-activated protein kinases (MAPKs) was decreased by ginsenoside Rg2 in BMM. Therefore, we suggest that ginsenoside Rg2 suppresses RANKL-induced osteoclast differentiation through the regulation of MAPK signaling-mediated osteoclast markers and could be developed as a therapeutic drug for the prevention and treatment of osteoporosis.

• Archives of Plastic Surgery
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• 제48권2호
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• pp.239-240
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• 2021

• 수완나부미
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• 제10권2호
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• pp.143-153
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• 2018

The paper comments on the contribution of Oscar Salemink on his personal intellectual journal from Vietnam to Europe and back again. This then leads to the contemplation of the construction of Southeast Asia as a "place" or "locality", early preoccupations within the region of the national dimension. And more recent developments in universities in Singapore, examining the continuing perceptions of Southeast Asia as a region and Singapore as its "gateway", and the increasing interest in "connectivities" and transnational relations between the region and other parts of Asia and the wider world.

• Molecules and Cells
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• 제28권3호
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• pp.201-207
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• 2009

Silibinin is a polyphenolic flavonoid compound isolated from milk thistle (Silybum marianum), with known hepatoprotective, anticarcinogenic, and antioxidant effects. Herein, we show that silibinin inhibits receptor activator of $NF-{\kappa}B$ ligand (RANKL)-induced osteoclastogenesis from RAW264.7 cells as well as from bone marrow-derived monocyte/macrophage cells in a dose-dependent manner. Silibinin has no effect on the expression of RANKL or the soluble RANKL decoy receptor osteoprotegerin (OPG) in osteoblasts. However, we demonstrate that silibinin can block the activation of $NF-{\kappa}B$, c-Jun N-terminal kinase (JNK), p38 mitogen-activated protein (MAP) kinase, and extracellular signal-regulated kinase (ERK) in osteoclast precursors in response to RANKL. Furthermore, silibinin attenuates the induction of nuclear factor of activated T cells (NFAT) c1 and osteoclast-associated receptor (OSCAR) expression during RANKL-induced osteoclastogenesis. We demonstrate that silibinin can inhibit $TNF-{\alpha}$-induced osteoclastogenesis as well as the expression of NFATc1 and OSCAR. Taken together, our results indicate that silibinin has the potential to inhibit osteoclast formation by attenuating the downstream signaling cascades associated with RANKL and $TNF-{\alpha}$.

• 대한한방부인과학회지
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• 제27권2호
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• pp.59-70
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• 2014

Purpose: This study was conducted to evaluate the inhibitory effect of ursolic acid from Prunella vulgaris on osteoclast differentiation. Methods: MTT-assay was performed to estimate cytotoxicity of ursolic acid from Prunella vulgaris in BMMs stimulated with M-CSF. TRAP staining, TRAP activity and Real-time PCR were performed to know the inhibitory effect on osteoclast differentiation. Actin ring formation were analysed to observe the effect of ursolic acid from Prunella vulgaris. Results: Ursolic acid from Prunella vulgaris has no cytotoxicity at the concentration of $1{\mu}g/ml$ or lower. Ursolic acid decreased the number of TRAP positive cells and the expression of NFATc1 gene, c-Fos gene, TRAP and OSCAR in BMMs stimulated with RANKL. Ursolic acid restrained the formation of actin ring. Ursolic acid inhibited NF-${\kappa}B$ activity by inducing degradation of p-$IkB{\alpha}$. Conclusions: Ursolic acid from Prunella vulgaris has the inhibitory effect of osteoclast differentiation and bone resorption. Futher studies are needed to treat osteoporosis by usolic acid from Prunella vulgaris.

• 대한한방부인과학회지
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• 제25권2호
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• pp.1-11
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• 2012

Objectives: This study was conducted to evaluate the inhibitory effect of Melia Fructus extract on osteoclast differentiation. Methods: MTT-assay was performed to estimate cytotoxicity of Melia Fructus extract in BMMs stimulated with M-CSF. TRAP staining, TRAP activity and Real-time PCR were performed to know the inhibitory effect on osteoclast differentiation. Actin ring formation were analysed to observe the effect of Melia Fructus extract. Results: Melia Fructus extract decreased the number of TRAP positive cells and the expression of NFATc1 gene, c-Fos gene, TRAP and OSCAR in BMMs stimulated with RANKL. Melia Fructus extract has no cytotoxicity at the concentration used in this study. Melia Fructus extract restrained the formation of actin ring. Melia Fructus inhibited NF-${\kappa}B$ activity by inducing degradation of p-$IkB{\alpha}$. Conclusions: Melia Fructus has the inhibitory effect of osteocalst differentiation and bone resorption. Further studies are needed to treat osteoporosis by herbal medicine containing Melia Fructus.