• 한국치위생학회지
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• 제18권6호
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• pp.921-932
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• 2018

Objectives: The aim of this study was to investigate the number of existing permanent teeth and the denture usage status in elderly adults aged 65 years and above living in metropolitan cities and to confirm the degree of oral health inequality caused by the differences in oral conditions in each metropolitan city using the Lorenz curve and the Gini coefficient. Methods: The raw data for the analysis were obtained from the dataset of the sixth Korea National Health and Nutrition Examination Survey conducted between 2013 and 2015. The subjects included 1,764 people who underwent oral examination and answered questions. The complex samples general linear model was used to analyze the number of existing permanent teeth adjusted for age and monthly household income. The proportion of edentulousness and the denture status was analyzed using complex samples crosstabs. Results: The number of existing permanent teeth in the elderly adults aged 65 years and above was lowest in Ulsan (15.41) and highest in Gwangju (20.44). The proportion of edentulousness was highest in Busan (14.5%) and lowest in Daejeon (4.0%). With regard to the proportion of denture users, Busan had the highest tendency for denture usage (50.4%) and Gwangju had the lowest tendency (34.9) (p=0.172). The Gini's coefficient for the number of existing teeth was lowest in Busan (0.332). Oral health inequality was most severe in metropolitan cities. Conclusions: We found that oral health inequality exists among elderly adults living in the metropolitan cities of Korea using the Lorenz curve and Gini's coefficient.

• 대한치과의사협회지
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• 제19권6호통권145호
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• pp.535-540
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• 1981

In order to collect the basic data for planning school dental health programmes, the author had examined dental health conditions of 120 males and 120 females of Changgyung Primary School children in the first grade. The percentages of persons with conditions requiring immediate attention, toothbrushing times and daily frequency, df rate, df index, dt index, ft index, it index, DMF rate, DT index, MT index, FT index, IT index, DMFT index, percentages of persons with periodontal status in every of the four categories with soft deposits, calculus, intense gingivitis, and advanced periodontal involvement were calculated and evaluated. The obtained results were as follows: 1. Persons with requiring immediate attention was 7.1% of all the examined children. 2. The df rate was 88.3%, and df index was 3.4 teeth per person. And then the DMF rate was 17.1%, while DMFT index was 0.3 teeth per person. 3. As the periodontal status, the persons with soft deposits was 90.0% of children, calculus 26.3%, intense gingivitis 0.4%, and no advanced periodontal involvement. 4. Average toothbrushing frquency was 1.2 times in a day per person. But 71.5% of toothbrushing was performed before meals, while the others after meals.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권2호
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• pp.171-175
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• 2011

Implant placement on the anterior mandible is considered a common and safe surgical procedure. However, severe hemorrhage can occur if branches of the sublingual artery, which run through the lingual cortical plate of the mandible, are damaged. Excessive hemorrhage caused by injury to the sublingual artery can result in life-threatening problems such as airway obstruction. A 54-year old male patient without any generalized systemic conditions was referred due to active bleeding after implant placement in the anterior mandible. Gauze compression with surgicel and bosimin were performed and hemostasis was achieved. The patient was discharged after 3 days without any supplementary bleeding.

• Imaging Science in Dentistry
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• 제49권4호
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• pp.287-294
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• 2019

Purpose: This study was performed to analyze the clinical and imaging features of contemporary osteomyelitis(OM) and to investigate differences in these features on panoramic radiography according to patients' history of use of medication affecting bone metabolism. Materials and Methods: The records of 364 patients(241 female and 123 male, average age 66.8±14.9 years) with OM were retrospectively reviewed. Panoramic imaging features were analyzed and compared between patients with medication-related OM(m-OM) and those with conventional, medication-unrelated OM(c-OM). Results: The age of onset of OM tended to be high, with the largest number of patients experiencing onset in their 70s. The 2 most frequent presumed causes were antiresorptive medication use (44.2%) and odontogenic origin (34.6%). On panoramic radiographs, a mix of osteolysis and sclerosis was the most common lesion pattern observed (68.6%). Sequestrum, extraction socket, and periosteal new bone formation were found in 143(42.1%), 79 (23.2%), and 24 (7.1%) cases, respectively. The m-OM group exhibited sequestrum and extraction socket more frequently and displayed significantly higher mandibular cortical index values than the c-OM group. Conclusion: We observed some differences in imaging features as shown on panoramic radiography according to the history of antiresorptive medication use. This study may help elucidate the predictive imaging features of medication-related osteonecrosis of the jaw.

• 한국치위생학회지
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• 제9권3호
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• pp.306-318
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• 2009

Objectives : There were reports about the decreasing of quit-smoking ratio because of taking professional advices. This study were to investigate smoking prevalence rate of the dental hygienist study in nationwide and quit-smoking counseling activity for patients in dental clinic. Methods : The registered Korea Dental Hygienists Association Meeting in 2005 were recruited as subjects. The personal surveyed, 486(87.7%) returned completed questionnaires. Results : The smoking rate of dental hygienist is 3.1%, past smoking rate 1.4% and smoking cessation 95.5%. In smoking cessation counseling activity, only 20.8% of dental hygienist would advise to quit smoking. However, 63.8% intended to advise to quit smoking but they have no idea about quit smoking program and 15.4% had no intention of advising to quit. It is a whole consent that Smoking dental hygienist is tend to against smoking and necessary training about smoking cessation same opinion. Conclusions : Dental hygienist is more effective for health care professional to help people stop smoking, therefore dental hygienist is important for them to have through knowledge of subject and confidence in their role in smoking cessation.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제32권6호
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• pp.504-510
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• 2010

Purpose: This study was to examine the proliferation and function of the adipose tissue-derived endothelial cells according to different culture medium conditions. Materials and Methods: Adipose tissue-derived CD146 positive endothelial cells were cultured in according to different culture mediums (DMEM culture medium with or without osteogenic inductive agents and EBM-2 culture medium with or without osteogenic inductive agents). The proliferation and function of the adipose tissue-derived endothelial cells was examined in different culture medium conditions. Results: Adipose tissue-derived endothelial cells formed tube-like structures on Matrigel in EBM-2 culture medium with or without osteogenic inductive agents. However, the cells did not form tube-like structures on Matrigel in DMEM medium with or without osteogenic inductive agents. After 24 hours of culture, among the culture medium using EBM-2, the proliferation of the cells were promoted in EBM-2 medium without osteogenic inductive agents than in EBM-2 medium with osteogenic inductive agents. However, 72 hours of culture, the proliferation of the cells were promoted in EBM-2 medium with osteogenic inductive agents than in EBM-2 medium without osteogenic inductive agents. Conclusion: These results suggest that the proliferation and function of the adipose tissue-derived CD146 positive endothelial cells could be maintained in EBM-2 with osteogenic inductive agents.

• The Korean Journal of Physiology and Pharmacology
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• 제16권5호
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• pp.333-337
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• 2012

Gene expression of neuronal nitric oxide synthase (nNOS) changes in the hypothalamic paraventricular nucleus (PVN) depending on feeding conditions, which is decreased during food deprivation and restored by refeeding, and phosphorylated cAMP response element binding protein (pCREB) was suggested to play a role in its regulation. This study was conducted to examine if the fasting-induced down-regulation of the PVN-nNOS expression is restored by activation of cAMP-dependent protein kinase A (cAMP/PKA) pathway. Freely moving rats received intracerebroventricular (icv) injection of cAMP/PKA activator Sp-cAMP (40 nmol) or vehicle (sterilized saline) following 48 h of food deprivation. One hour after drug injections, rats were transcardially perfused with 4% paraformaldehyde, and the PVN tissues were processed for nNOS or pCREB immunohistochemistry. Sp-cAMP significantly increased not only nNOS but also pCREB immunoreactivities in the PVN of food deprived rats. Fastinginduced down-regulation of the PVN-nNOS was restored by 1 h after the icv Sp-cAMP. Results suggest that cAMP/PKA pathway may mediate the regulation of the PVN-nNOS expression depending on different feeding conditions.

• Journal of Microbiology and Biotechnology
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• 제31권5호
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• pp.705-709
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• 2021

Porphyromonas gingivalis (P. gingivalis) is a major bacterial pathogen that causes periodontitis, a chronic inflammatory disease of tissues around the teeth. Periodontitis is known to be related to other diseases, such as oral cancer, Alzheimer's disease, and rheumatism. Thus, a precise and sensitive test to detect P. gingivalis is necessary for the early diagnosis of periodontitis. The objective of this study was to optimize a rapid visual detection system for P. gingivalis. First, we performed a visual membrane immunoassay using 3,3',5,5'-tetramethylbenzidine (TMB; blue) and coating and detection antibodies that could bind to the host laboratory strain, ATCC 33277. Antibodies against the P. gingivalis surface adhesion molecules RgpB (arginine proteinase) and Kgp (lysine proteinase) were determined to be the most specific coating and detection antibodies, respectively. Using these two selected antibodies, the streptavidin-horseradish peroxidase (HRP) reaction was performed using a nitrocellulose membrane and visualized with a detection range of 10³-10⁵ bacterial cells/ml following incubation for 15 min. These selected conditions were applied to test other oral bacteria, and the results showed that P. gingivalis could be detected without cross-reactivity to other bacteria, including Streptococcus mutans and Escherichia fergusonii. Furthermore, three clinical strains of P. gingivalis, KCOM 2880, KCOM 2803, and KCOM 3190, were also recognized using this optimized enzyme immunoassay (EIA) system. To conclude, we established optimized conditions for P. gingivalis detection with specificity, accuracy, and sensitivity. These results could be utilized to manufacture economical and rapid detection kits for P. gingivalis.

• 대한장애인치과학회지
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• 제10권2호
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• pp.61-67
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• 2014

The aim of this study was to analyze the clinical characteristics of patients with cognitive and behavioral impairments receiving dental treatment under general anesthesia (GA-dental treatment). From August 2007 to April 2014, information was collected from 475 patients who received GA-dental treatment at the Clinic for Persons with Disabilities, Seoul National University Dental Hospital. The demographic factors (gender, age, disability, medication, GA history, residency type, caregiver, meal type, oral hygiene maintenance, and cooperation level) and dental status (operating duration, DMFT, malocclusion, periodontal disease, tooth defect, and treatment protocol) of the patients were evaluated. DMFT and malocclusion levels were compared among the patients with ANOVA and Sheffe's post-hoc test, and chi-square test, respectively. The correlation between the demographic characteristics and dental status of the patients were analyzed with the Pearson's correction test. The mean age of the patients was 27.1 (7 - 83) years and they had intellectual disabilities (55.4%), developmental disorders (17.9%), brain disorders (16.6%), neurocognitive disorders (4.6%), or others (5.5%). The mean DMFT (DT) was 8.6 (5.2) with a significant difference among the disability types (p<0.05). The incidence of malocclusion was higher in patients with intellectual disabilities and brain disorders than in the other types (p<0.05). The operation time ($191.4{\pm}91.2min$) was correlated with decayed or endodontically-treated teeth (p<0.05). Special needs patients requiring GA-dental treatment showed unfavorable oral conditions. Dental practitioners experience time restrictions and additional costs under a GA setting. Treatment planning and decision-making can be efficiently facilitated by evaluating the clinical characteristics of the patients.

• Nutrition Research and Practice
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• 제14권2호
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• pp.143-151
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• 2020

BACKGROUND/OBJECTIVES: The nutrition of the elderly depends on various factors. Oral health, especially oral dryness, can be an important risk factor. In this study, we attempted to determine whether dry mouth is associated with compromised nutrient intakes. SUBJECTS/METHODS: A total of 120 participants aged 65-86 yrs (mean age: 69 ± 1 y) were included in this study. Demographic and health-related characteristics, living status, meals, number of medications, medical conditions, chewing ability, and quality of life, the Oral Health Impact Profile (the OHIP-14) were assessed. We performed one day 24-hr recall assessment for nutrient analyses. The differences of the means between the dry-mouth and non-dry-mouth groups were analyzed. Elderly subjects with xerostomia-induced dry mouth were classified as those who reported at least one dryness symptom on a questionnaire. RESULTS: A significant difference in population distribution was observed among the elderly who took medications for hypertension, diabetes and osteoporosis and was significantly higher in the dry-mouth group (70.2%) than in the non-dry-mouth group (44.4%) (P = 0.005). Compared with the non-dry-mouth group (50.8%), a significantly higher proportion (73.7%) of participants in the dry-mouth group took multiple medicines (≥ 4 medications) (P = 0.019). The intakes of vegetable fat, vitamin E, folate and water in the dry-mouth group were lower than in the non-dry-mouth group. The intakes of fluoride and ω-3 fatty acids were significantly lower in the dry-mouth group than in the non-dry-mouth group. CONCLUSION: The participants in the dry-mouth group exhibited low nutrient and water intakes. It is recommended that the elderly with dry mouth should drink sufficient water and receive targeted and specific nutritional guidance to prevent malnutrition.