• Title/Summary/Keyword: Optimum efficiency

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Development of Porous Cellulose-Hydrogel System for Enhanced Transdermal Delivery of Quercetin and Rutin (Quercetin과 Rutin의 피부 흡수 증진을 위한 셀룰로오스 다공성 하이드로젤 제형 개발)

  • Lee, Min Hye;Kim, Su Ji;Park, Soo Nam
    • Polymer(Korea)
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    • v.37 no.3
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    • pp.347-355
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    • 2013
  • In this study, the porous cellulose hydrogel as a carrier to enhance the skin delivery of quercetin and its glycoside, rutin known as flavonoid antioxidants was prepared and its properties were investigated. The optimum cellulose hydrogel for quercetin and rutin was made by the reaction of 2 wt% cellulose with 12% ECH. In the release test of the hydrogel containing the flavonoids, the release of quercetin was diffusion-controlled at $10{\sim}500{\mu}M$, but rutin was released by the erosion of hydrogel system at $10{\sim}50{\mu}M$. Both the encapsulation efficiency and release amount of rutin in hydrogel were higher than quercetin. However, in skin permeation experiment using Franz diffusion cell, quercetin showed higher skin permeation capacity than rutin. The hydrogel containing flavonoids showed remarkable transdermal permeation than the control group. These results suggest that porous cellulose hydrogel is potential drug delivery system to enhance transdermal permeation of water-insoluble flavonoid antioxidants.

Contribution of Soil Pysico-chemical Properties to Fruit Quality of 'Campbell Early' Grapes in the Vineyards (포도 '캠벨얼리' 품질에 미치는 토양이화학성의 상대적 기여도)

  • Kim, Seung-Heui;Choi, In-Myung;Yun, Seok-Kyu;Cho, Jung-Gun;Lim, Tae-Jun;Yun, Hae-Keun
    • Korean Journal of Soil Science and Fertilizer
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    • v.42 no.3
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    • pp.187-191
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    • 2009
  • 'Campbell Early', a major grape cultivar, occupies more than 70% of cultivated vineyard areas, however, recommendable standard management system of soil environmental conditions has not been developed yet in Korea. The consideration for the correlation between fruit quality and soil condition in the vineyard is required in the efficient management system of soil. This study was carried out to investigate the optimum soil environmental conditions for 'Campbell Early' grape production with high quality. The results from analyses of correlation between them were used to develop soil management guideline for promoting efficiency in grape production. Soil properties were analyzed from 120 vineyards in Hawsung, Sangju, Yeongdong, Gimcheon, Yeongju, and Yeongwol, major grape production regions. Because there is neither coloring disorder nor delayed coloration in grape production of 'Campbell Early', relative contribution of soil hardness and solid phase to fruit quality and fruit weight was analyzed. Among the soil properties, while cation and soil hardness affected sugar content at the level of 39.3% and 36.8%, respectively, saturated hydraulic conductivity, solid phase, and cation exchange capacity (CEC) showed relatively low contribution to sugar content in the vineyard. The sugar content in grapes was influenced more critically by the chemical properties than the physical ones in the soil of vineyards. While soil hardness and solid phase affected grape weight at the level of 27.8% and 26.0%, respectively, phosphate content, organic matter content, and cation showed low contribution to grape weight. Grape guality such as sugar content and grape weight was affected highly by cation and organic matters. Therefore, cation and organic matter content of soil contributed to fruit quality at the level of 33.8% and 15.5%, respectively, in the vineyard.

Establishment of Callus Induction and Plant Regeneration System from Mature Seeds of Miscanthus sinensis (억새(Miscanthus sinensis) 성숙 종자로부터의 캘러스 유도 및 식물체 재분화 체계 확립)

  • Cho, Joon-Hyeong;Byeon, Ji-Hui
    • Korean Journal of Plant Resources
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    • v.24 no.5
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    • pp.628-635
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    • 2011
  • This study was conducted to establish the tissue culture system for Korean domestic Miscanthus sinensis, which is used in various purposes such as forage, and bio-energy resources. With the mature seed of Miscanthus, optimum concentrations of plant growth regulators were identified for an efficient callus induction and regeneration. Among the treatments of 1~10 $mg{\cdot}L^{-1}$ 2,4-D, IBA, or NAA, callus induction rate was highest (85.3%) on MS medium containing 5 $mg{\cdot}L^{-1}$ 2,4-D. Under the condition, the callus were efficiently induced and proliferated with comparably lower frequencies of callus browning. In shoot regeneration, the treatment of NAA combined with BAP seemed to contribute more efficient conditions to shoot regeneration than those of NAA with Kinetin or 2-iP. Especially, regeneration efficiency and number of regenerated plants were 83.7% and 5.5 in 3 $mg{\cdot}L^{-1}$ NAA with 5 $mg{\cdot}L^{-1}$ BAP, respectively, which were higher frequencies than those in NAA with Kinetin or 2-iP. In results, 5 $mg{\cdot}L^{-1}$ 2,4-D and 3 $mg{\cdot}L^{-1}$ NAA combined with 5 $mg{\cdot}L^{-1}$ BAP were efficient for embryogenic callus induction and regeneration of Miscanthus. This system would be useful for mass-propagation and developing new cultivars via tissue culture of Miscanthus sinensis.

Development of a Bioscrubber for Treatment of VOC Emissions from Contaminated Soil with Hydrocarbons (유류오염토양으로부터 발생하는 VOC가스처리를 위한 바이오스크러버 개발)

  • 장윤영;황경엽;곽재호;최대기
    • Journal of Korea Soil Environment Society
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    • v.2 no.1
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    • pp.83-90
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    • 1997
  • Aiming at the treatment of large volumes of gas with a low concentration of poorly water soluble VOC(Volatile Organic Compound), a new system is proposed: the combination absorption tower/bioreactor. In the scrubber part of the bioscrubbing system, the contaminating compounds are absorbed in a aqueous phase. The contaminated scrubbing liquid is transported to the bioreactor, where the compounds are biodegraded by aerobic microorganisms (mainly to carbon dioxide, water, and biomass). In this study, separation of a volatile organic compound(VOC) out of a waste gas stream has been carried out using a re-cyclable high boiling point extrant(HBE). The liquid stream containing a high boiling point entrant(HBE) scrubs the gas stream in a direct gas-liquid countercurrent contacting operation in a packed tower for the removal of said component from the gaseous stream. A packed-bed column using Pall Ring was set up in order to simulate practical conditions for the scrubbing tower. The liquid stream transported to the bioreactor is recovered and recycled to the scrubber. The model gas, which contained 400 mg/$\textrm{m}^3$ of toluene, at a rate of 100 L/min, flowed into the packed column where the scrubbing liquid trickled over the packing in countercurrent to the rising gas at 10~15L/min. The bioscrubber designed for large volume air streams containing VOCs showed removal efficiency up to 80% in an optimum operating conditions during the tests fer removing toluene from an air stream by scrubbing the air stream with HBE.

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Uranyl Peroxide Compound Preparation from the Filtrate for Nuclear Fuel Powder Production Process (핵연료분말 제조공정 여액으로부터 Uranyl-peroxide 화합물의 제조)

  • Jeong, Kyung-Chai;Kim, Tae-Joon;Choi, Jong-Hyun;Park, Jin-Ho;Hwang, Seong-Tae
    • Applied Chemistry for Engineering
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    • v.8 no.3
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    • pp.430-437
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    • 1997
  • Uranyl-peroxide compound was prepared by the reaction of excess hydrogen peroxide solution and trace uranium in filtrate from nuclear fuel conversion plant. The $CO_3{^{2-}}$ in filtrate was removed first by heating more than $98^{\circ}C$, because uranyl-peroxide compound could not be precipitated by $CO_3{^{2-}}$ remaining in filtrate. The optimum condition for uranyl-peroxide compound was ageing for 1 hr after controling the pH with $NH_3$ gas and adding the excess $H_2O_2$ of 10ml/lit.-filtrate. Uranium concentration in the filtrate was appeared to 3 ppm after the precipitation of uranyl-peroxide compound, and the chemical composition of this compound was analyzed to $UO_4{\cdot}2NH_4F$ with FT-IR, X-ray diffractometry, TG and chemical analysis. Also, this fine particle, about $1{\sim}2{\mu}m$, could be grown up to $4{\mu}m$ at pH 9.5 and $60^{\circ}C$. The separation efficiency of precipitate from mother liquor was increased with increase of pH and reaction temperature. Otherwise, the crystal form of this particle showed octahedral by SEM and XRD, and $U_3O_8$ powder was obtained by thermal decomposition at $650^{\circ}C$ in air atmosphere.

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Pozzolanicity of Calcined Sewage Sludge with Calcination and Fineness Conditions (소성조건 및 분말도에 따른 소성하수슬러지(CSS)의 포졸란 특성)

  • So, Hyoung-Seok;So, Seung-Young;Khulgadai, Janchivdorj;Kang, Jae-Hong;Lee, Min-Hi
    • Journal of the Korea Concrete Institute
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    • v.27 no.1
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    • pp.65-73
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    • 2015
  • This study discussed the pozzolanic properties of calcined sewage sludge (CSS) according to calcination and fineness conditions. The chemical and mineralogical analysis of CSS according to calcination temperature and time were carried out and compared with that of the existing pozzolanic materials such as fly-ash, blast furnance slag and meta-kaolin. Various mortars were made by mixing those CSS and $Ca(OH)_2$ (1:1 wt. %), and their compressive strength and hydrates according to experimental factors such as fineness of CSS and curing age were also investigated in detail. The results show clearly the potentiality of calcined sewage sludge (CSS) as an admixture materials in concrete, but the CSS should be controlled by calcination temperature and time, and fineness etc. In this experimental condition, the calcination temperature of $800^{\circ}C$, calcination time of 2 hours and fineness of $5,000cm^2/g$ were optimum conditions in consideration of the mechanical properties and economic efficiency of CSS. The compressive strength of CSS mortars was higher than that of fly-ash mortars and blast furnace slag mortars, especially at the early ages. Then, the utilization of CSS in construction fields was greatly expected.

Characteristics of Strength Development of Ultra-High Performance Concrete according to Curing Condition (초고성능 콘크리트의 양생 조건에 따른 강도 발현 특성)

  • Park, Jong-Sup;Kim, Young-Jin;Cho, Jeong-Rae;Jeon, Se-Jin
    • Journal of the Korea Concrete Institute
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    • v.25 no.3
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    • pp.295-304
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    • 2013
  • Ultra-High Performance Concrete (UHPC) has recently been one of the most active research fields in Korea as well as in foreign countries, because it can contribute to a longer life and economic efficiency of structures. Although precast-type UHPC fabricated in a factory is preferable in terms of quality control and reduction of construction period, there exist, even in the precast structure, some parts that need to be cast in-place such as the joints between precast segments. In the cast-in-place UHPC, however, it is probable that an optimum curing condition can hardly be realized in contrast to the factory production. In this study, therefore, the trend of compressive strength development of UHPC was experimentally investigated by assuming various inferior curing conditions that may be anticipated at a construction site. Concrete specimens were fabricated and cured under different conditions with the variables such as curing temperature, delay time before the initiation of curing, duration of curing time and moisture condition. The strengths were compared with those of the specimens cured by standard high temperature steam. Through the analysis of the test results, some minimum requirements for curing have been proposed that are required when the UHPC is cast in-place. It is expected, through this study, that practical use of UHPC in construction sites can be increased.

The Post Annealing Effect of Organic Thin Film Solar Cells with P3HT:PCBM Active Layer (P3HT:PCBM 활성층을 갖는 유기 박막태양전지의 후속 열처리 효과)

  • Jang, Seong-Kyu;Gong, Su-Cheol;Chang, Ho-Jung
    • Journal of the Microelectronics and Packaging Society
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    • v.17 no.2
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    • pp.63-67
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    • 2010
  • The organic solar cells with Glass/ITO/PEDOT:PSS/P3HT:PCBM/Al structure were fabricated using regioregular poly (3-hexylthiophene) (P3HT) polymer:(6,6)- phenyl $C_{61}$-butyric acid methyl ester (PCBM) fullerene polymer as the bulk hetero-junction layer. The P3HT and PCBM as the electron donor and acceptor materials were spin casted on the indium tin oxide (ITO) coated glass substrates. The optimum mixing concentration ratio of photovoltaic layer was found to be P3HT:PCBM = 4:4 in wt%, indicating that the short circuit current density ($J_{SC}$), open circuit voltage ($V_{OC}$), fill factor (FF) and power conversion efficiency (PCE) values were about 4.7 $mA/cm^2$, 0.48 V, 43.1% and 0.97%, respectively. To investigate the effects of the post annealing treatment, as prepared organic solar cells were post annealed at the treatment time range from 5min to 20min at $150^{\circ}C$. $J_{SC}$ and $V_{OC}$ increased with increasing the post annealing time from 5min to 15min, which may be originated from the improvement of the light absorption coefficient of P3HT and improved ohmic contact between photo voltaic layer and Al electrode. The maximum $J_{SC},\;V_{OC}$, FF and PCE values of organic solar cell, which was post annealed for 15min at $150^{\circ}C$, were found to be about 7.8 $mA/cm^2$, 0.55 V, 47% and 2.0%, respectively.

Bearing Capacity Reinforcing Effect of Forest Road Surface by Construction of Sub-base using Geosynthetics (토목섬유 활용 노반 조성을 통한 임도 노면지지력 강화효과 분석)

  • Hwang, Jin-Seong;Ji, Byoung-Yun;Lee, Kwan-Hee;Kweon, Hyeong-Keun;Kim, Myung-Hwan
    • Journal of Korean Society of Forest Science
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    • v.107 no.2
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    • pp.166-173
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    • 2018
  • This study was carried out to establish the standard of sub-base facility which can strengthen road surface bearing capacity for smooth passage of logging trucks in forest road as the size of the logging truck has been increased in order to improve the efficiency of timber transportation. The results of reinforcement effect analysis of the surface bearing capacity by the thickness of sub-base prepared with the optimum aggregate mix ratio using geosynthetics for forest road on the soft ground in the Forest Technology and Management Research Center are as follows. The surface bearing capacity of CBR exceeding 15% was found to be sufficient when the sub-base was constructed over 0.2 m depth of laying gravels with installation of geosynthetics after digging out subsoil. However, there is no significant difference in reinforcement effect of surface bearing capacity by types of geosynthetics. And, it was found that the surface bearing capacity was insufficient in the installation of sub-base. Therefore, in the case of soft ground, It is possible to secure the reinforcement of the surface bearing capacity for the smooth passage of heavy logging trucks by sub-base, that was constructed over 0.2 m depth of laying gravels with installation of geosynthetics after digging out subsoil.

Practical Virtual Compensator Design with Dynamic Multi-Leaf Collimator(dMLC) from Iso-Dose Distribution

  • Song, Ju-Young;Suh, Tae-Suk;Lee, Hyung-Koo;Choe, Bo-Young;Ahn, Seung-Do;Park, Eun-Kyung;Kim, Jong-Hoon;Lee, Sang-Wook;Yi, Byong-Yong
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.129-132
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    • 2002
  • The practical virtual compensator, which uses a dynamic multi-leaf collimator (dMLC) and three-dimensional radiation therapy planning (3D RTP) system, was designed. And the feasibility study of the virtual compensator was done to verify that the virtual compensator acts a role as the replacement of the physical compensator. Design procedure consists of three steps. The first step is to generate the isodose distributions from the 3D RTP system (Render Plan, Elekta). Then isodose line pattern was used as the compensator pattern. Pre-determined compensating ratio was applied to generate the fluence map for the compensator design. The second step is to generate the leaf sequence file with Ma's algorithm in the respect of optimum MU-efficiency. All the procedure was done with home-made software. The last step is the QA procedure which performs the comparison of the dose distributions which are produced from the irradiation with the virtual compensator and from the calculation by 3D RTP. In this study, a phantom was fabricated for the verification of properness of the designed compensator. It is consisted of the styrofoam part which mimics irregular shaped contour or the missing tissues and the mini water phantom. Inhomogeneous dose distribution due to the styrofoam missing tissue could be calculated with the RTP system. The film dosimetry in the phantom with and without the compensator showed significant improvement of the dose distributions. The virtual compensator designed in this study was proved to be a replacement of the physical compensator in the practical point of view.

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