• Title/Summary/Keyword: Optimization of Operation Conditions

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Production of Alkaline Protease by Entrapped Bacillus licheniformis Cells in Repeated Batch Process

  • Mashhadi-Karim, Mohammad;Azin, Mehrdad;Gargari, Seyyed Latif Mousavi
    • Journal of Microbiology and Biotechnology
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    • v.21 no.12
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    • pp.1250-1256
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    • 2011
  • In this study, Bacillus licheniformis cells were immobilized by entrapment in calcium alginate beads and were used for production of alkaline protease by repeated batch process. In order to increase the stability of the beads, the immobilization procedure was optimized by statistical full factorial method, by which three factors including alginate type, calcium chloride concentration, and agitation speed were studied. Optimization of the enzyme production medium, by the Taguchi method, was also studied. The obtained results showed that optimization of the cell immobilization procedure and medium constituents significantly enhanced the production of alkaline protease. In comparison with the free-cell culture in pre-optimized medium, about 7.3-fold higher productivity was resulted after optimization of the overall procedure. Repeated batch mode of operation, using optimized conditions, resulted in continuous production of the alkaline protease for 13 batches in 19 days.

Development of an Efficient Operation Method for PCB Assembly Line with 3 Gantry-Type Machines (3대의 갠트리 기계로 구성된 PCB조립라인의 최적운영 방안 연구)

  • Moon, Gee-Ju;Jeon, Moon-Gil
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.33 no.4
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    • pp.138-144
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    • 2010
  • This research deals with multiple Gantry-type assembly machines for the optimization of PCB assembly line. The automated assembly machine has 6 nozzles which can linearly move the X axis and the Y axis different from the turret type assembly machine. Each machine is optimized while considering the whole line balancing of three machines in assembly process simultaneously. Simulation models are developed using AutoMod for comparison study with single machine operation cases under various conditions such as types and total number of components to evaluate the proposed method.

Development of Three Phase Optimal Power Flow for Distributed Generation Systems (분산전원계통을 위한 3상 최적조류계산 프로그램 개발)

  • Song, Hwa-Chang;Cho, Sung-Koo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.5
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    • pp.882-889
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    • 2010
  • This paper presents a method of finding the optimal operating point minimizing a given objective function with 3 phase power flow equations and operational constraints, called 3 phase optimal power flow (3POPF). 3 phase optimal power flow can provide operation and control strategies for the distribution systems with distributed generation assets, which might be frequently in unbalanced conditions assuming that high penetration rate of renewable energy sources in the systems. As the solution technique for 3POPF, this paper adopts a simulation-based method of particle swarm optimization (PSO). In the PSO based 3POPF, a utility function needs to be defined for evaluation of the degree in operational improvement of each particle's current position. To evaluate the utility function, in this paper, NR-based 3 phase power flow algorithm was developed which can deal with looped distributed generation systems. In this paper, illustrative examples with a 5-bus and a modified IEEE 37-bus test systems are given.

A Study on the Determination of the Oil Gap in the Hydrostatic Spindle System for a Crank Shaft Grinding Machine (크랭크 샤프트 연삭기용 유정압 스핀들의 유막 간격 선정에 관한 연구)

  • Park, Dong-Keun;Choi, Chi-Hyuk;Lee, In-Jae;Lee, Choon-Man
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.4
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    • pp.410-415
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    • 2011
  • A cylindrical type of self-controlled restrictor is designed for hydrostatic bearing of crank shaft for a grinding wheel spindle. The effect of operation parameters, clearance between spindle and housing on bearing stiffness are analyzed to determine the optimum conditions of operation parameters. The lowest values of the supply pressure and the loads by the theoretical and experimental results assuming oil film thickness and shape of pocket are compared.

Assessment and Optimization of Granular Activated Carbon (GAC) Process in Water Treatment Process (입상활성탄 공정의 진단 및 효율적 운영방안: D 정수장을 중심으로)

  • Kim, Seong Su;Lee, Kyung Hyuk
    • Journal of Korean Society of Water and Wastewater
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    • v.19 no.6
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    • pp.781-790
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    • 2005
  • Granular Activated Carbon(GAC) is widely used in drinking water treatment. Many of the problems occurring in the GAC process are associated with the operation goal and performance. The purpose of this study were to evaluate the design, operation, and performance of granular activated carbon process in D water treatment plant. The optimal operation conditions of GAC process such as backwashing condition, granular activated carbon replacement time were discussed. The design, operation and performance of GAC process is influenced by their raw water characteristics and placement within the treatment process sequence. A critical analysis of plants experience and the information from the literature identifies the effectiveness of GAC process and indicates where modifications in design and operation could lead to improved performance. It would be useful to evaluate and optimize the GAC process in other treatment plant.

Optimization of Process Variables for the Soda Pulping of Carpolobia Lutea (Polygalaceae) G. Don

  • Ogunsile, B.O.;Uba, F.I.
    • Journal of the Korean Chemical Society
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    • v.56 no.2
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    • pp.257-263
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    • 2012
  • The selection of suitable delignification conditions and optimization of process variables is crucial to the successful operation of chemical pulping processes. Soda pulping of Carpolobia lutea was investigated, as an alternative raw material for pulp and paper production. The process was optimized under the influence of three operational variables, namely, temperature, time and concentration of cooking liquor. Equations derived using a second - order polynomial design predicted the pulp yield and lignin dissolution with errors less than 8% and 11% respectively. The maximum variations in the pulp yield using a second order factorial design was caused by changes in both time and alkali concentration. Optimum pulp yield of 43.87% was obtained at low values of the process variables. The selectivity of lignin dissolution was independent of the working conditions, allowing quantitative estimations to be established between the pulp yield and residual lignin content within the range studied.

Experimental Analysis for Optimization of PEM Fuel Cell Dead-end Operation (고분자전해질 연료전지 Dead-end 운전 최적화에 대한 실험적인 연구)

  • Lee, Bonggu;Sohn, Young-Jun
    • Transactions of the Korean hydrogen and new energy society
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    • v.26 no.2
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    • pp.136-147
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    • 2015
  • Dead-ended operation of Proton Exchange Membrane Fuel Cell(PEMFC) provides the simplification of fuel cell systems to reduce fuel consumption and weight of fuel cell. However, the water accumulation within the channel prohibits a uniform supply of fuel. Optimization of the purge strategy is required to increase the fuel cell efficiency since fuel and water are removed during the purge process. In this study, we investigated the average voltage output which depends on two interrelated conditions, namely, the supply gas pressure, purging valve open time. In addition, flow visualization was performed to better understand the water build-up on the anode side and cathode side of PEMFC in terms of a variety of the current density. We analyzed the correlation between the purge condition and water flooding.

OPTIMUM STORAGE REALLOCATION AND GATE OPERATION IN MULTIPURPOSE RESERVOIRS

  • Hamid Moradkhani
    • Water Engineering Research
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    • v.3 no.1
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    • pp.57-62
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    • 2002
  • This research is intended to integrate long-term operation rules and real time operation policy for conservation & flood control in a reservoir. The familiar Yield model has been modified and used to provide long-term rule curves. The model employs linear programming technique under given physical conditions, i.e., total capacity, dead storage, spillways, outlet capacity and their respective elevations to find required and desired minimum storage fur different demands. To investigate the system behavior resulting from the above-mentioned operating policy, i.e., the rule curves, the simulation model was used. Results of the simulation model show that the results of the optimization model are indeed valid. After confirmation of the above mentioned rule curves by the simulation models, gate operation procedure was merged with the long term operation rules to determine the optimum reservoir operating policy. In the gate operation procedure, operating policy in downstream flood plain, i.e., determination of damaging and non-damaging discharges in flood plain, peak floods, which could be routed by reservoir, are determined. Also outflow hydrograph and variations of water surface levels for two known hydrographs are determined. To examine efficiency of the above-mentioned models and their ability in determining the optimum operation policy, Esteghlal reservoir in Iran was analyzed as a case study. A numerical model fur the solution of two-dimensional dam break problems using fractional step method is developed on unstructured grid. The model is based on second-order Weighted Averaged Flux(WAF) scheme with HLLC approximate Riemann solver. To control the nonphysical oscillations associated with second-order accuracy, TVD scheme with SUPERBEE limiter is used. The developed model is verified by comparing the computational solutions with analytic solutions in idealized test cases. Very good agreements have been achieved in the verifications.

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Bayesian Optimization Analysis of Containment-Venting Operation in a Boiling Water Reactor Severe Accident

  • Zheng, Xiaoyu;Ishikawa, Jun;Sugiyama, Tomoyuki;Maruyama, Yu
    • Nuclear Engineering and Technology
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    • v.49 no.2
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    • pp.434-441
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    • 2017
  • Containment venting is one of several essential measures to protect the integrity of the final barrier of a nuclear reactor during severe accidents, by which the uncontrollable release of fission products can be avoided. The authors seek to develop an optimization approach to venting operations, from a simulation-based perspective, using an integrated severe accident code, THALES2/KICHE. The effectiveness of the containment-venting strategies needs to be verified via numerical simulations based on various settings of the venting conditions. The number of iterations, however, needs to be controlled to avoid cumbersome computational burden of integrated codes. Bayesian optimization is an efficient global optimization approach. By using a Gaussian process regression, a surrogate model of the "black-box" code is constructed. It can be updated simultaneously whenever new simulation results are acquired. With predictions via the surrogate model, upcoming locations of the most probable optimum can be revealed. The sampling procedure is adaptive. Compared with the case of pure random searches, the number of code queries is largely reduced for the optimum finding. One typical severe accident scenario of a boiling water reactor is chosen as an example. The research demonstrates the applicability of the Bayesian optimization approach to the design and establishment of containment-venting strategies during severe accidents.

Hydrodynamic Design of Thrust Ring Pump for Large Hydro Turbine Generator Units

  • Lai, Xide;Zhang, Xiang;Chen, Xiaoming;Yang, Shifu
    • International Journal of Fluid Machinery and Systems
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    • v.8 no.1
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    • pp.46-54
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    • 2015
  • Thrust-ring-pump is a kind of extreme-low specific speed centrifugal pump with special structure as numerous restrictions from thrust bearing and operation conditions of hydro-generator units. Because the oil circulatory and cooling system with thrust-ring-pump has a lot of advantages in maintenance and compactness in structure, it has widely been used in large and medium-sized hydro-generator units. Since the diameter and the speed of the thrust ring is limited by the generator set, the matching relationship between the flow passage inside the thrust ring (equivalent to impeller) and oil bath (equivalent to volute) has great influence on hydrodynamic performance of thrust-ring-pump. On another hand, the head and flow rate are varying with the operation conditions of hydro-generator units and the oil circulatory and cooling system. As so far, the empirical calculation method is employed during the actual engineering design, in order to guarantee the operating performance of the oil circulatory and cooling system with thrust-ring-pump at different conditions, a collaborative hydrodynamic design and optimization is purposed in this paper. Firstly, the head and flow rate at different conditions are decided by 1D flow numerical simulation of the oil circulatory and cooling system. Secondly, the flow passages of thrust-ring-pump are empirically designed under the restrictions of diameter and the speed of the thrust ring according to the head and flow rate from the simulation. Thirdly, the flow passage geometry matching optimization between thrust ring and oil bath is implemented by means of 3D flow simulation and performance prediction. Then, the pumps and the oil circulatory and cooling system are collaborative hydrodynamic optimized with predicted head-flow rate curve and the efficiency-flow rate curve of thrust-ring-pump. The presented methodology has been adopted by DFEM in design process of thrust-ring-pump and it shown can effectively improve the performance of whole system.