• Title/Summary/Keyword: Optimal site and size

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The Optimal Shock Intensity and C-arm Total Running Time in Patients with Inferior Ureter Stones during Electromagnetic of ESWL (전자기식 체외충격파쇄석술시 하부요관 결석 환자에 대해 적합한 충격강도와 C-arm 총 가동시간)

  • Park, Jeong Kyu;Cho, Euy Hyun
    • Journal of the Korean Society of Radiology
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    • v.8 no.7
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    • pp.461-466
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    • 2014
  • The advantages and disadvantages of the various models of crushed ESWL (Extracorporeal Shock Wave Lithotripsy) and their various side effects due to pre-treatment have been reported. We look for the appropriate intensity of the shock wave in the electromagnetic ESWL treatment of patients with lower Inferior Ureter Stones and measure the total running time of C-arm saw. This study is based on the January-June 2014 launch of 65 patients of C university hospital located in Gyeongbuk, who conducted ESWL without pre-treatment. Patients are composed of 48 male and 17 female which were more common in men, while the most common age is 50s. The occurrence of lower urinary tract stones were left and they were more absent than 5mm in size in 39 of the most common. Optimal intensity is one of the suitable intensity of pain, and it is possible to switch the strength of impact to C if one appeals pain. In addition, the C-arm of the total operating time showed $241.73{\pm}30.37$ seconds, which is the size of the lower urinary tract that showed a significant difference (p <0.05). Therefore, ESWL treatment without pre-enforce treatment, the standard for the impact frequency and impact strength depending on the site of ureteral stones is required. The standard for total operating time of C-arm generated for ureteral stones is needed in order to reduce radiation exposure, and the standard for the total operating time for the criteria is needed depending on the site in order to minimize the exposure.

Experimental study on ultra-high strength concrete(130 MPa) (초고강도 콘크리트(130MPa)에 대한 실험적 연구)

  • Cho Choonhwan;Yang Dong-il
    • Journal of the Korea Institute of Construction Safety
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    • v.6 no.1
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    • pp.12-18
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    • 2024
  • High-rise, large-scale, and diversification of buildings are possible, and the reduction of concrete cross-sections reduces the weight of the structure, thereby increasing or decreasing the height of the floor, securing a large number of floors at the same height, securing a large effective space, and reducing the amount of materials, rebar, and concrete used for designating the foundation floor. In terms of site construction and quality, a low water binder ratio can reduce the occurrence of dry shrinkage and minimize bleeding on the concrete surface. It has the advantage of securing self-fulfilling properties by improving fluidity by using high-performance sensitizers, making it easier to construct the site, and shortening the mold removal period by expressing early strength of concrete. In particular, with the rapid development of concrete-related construction technology in recent years, the application of ultra-high-strength concrete with a design standard strength of 100 MPa or higher is expanding in high-rise buildings. However, although high-rise buildings with more than 120 stories have recently been ordered or scheduled in Korea, the research results of developing ultra-high-strength concrete with more than 130 MPa class considering field applicability and testing and evaluating the actual applicability in the field are insufficient. In this study, in order to confirm the applicability of ultra-high-strength concrete in the field, a preliminary experiment for the member of a reduced simulation was conducted to find the optimal mixing ratio studied through various indoor basic experiments. After that, 130 MPa-class ultra-high-strength concrete was produced in a ready-mixed concrete factory in a mock member similar to the life size, and the flow characteristics, strength characteristics, and hydration heat of concrete were experimentally studied through on-site pump pressing.

Identification and characterization of laccase genes in the Flammulina velutipes var. lupinicola genome (Flammulina velutipes var. lupinicola의 유전체 정보기반 laccase 유전자 동정 및 특성 규명)

  • Yu, Hye-Won;Park, Young-Jin
    • Journal of Mushroom
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    • v.19 no.4
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    • pp.285-293
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    • 2021
  • The purpose of this study was to identify and characterize the laccase genes of Flammulina velutipes var. lupinicola. Five laccase genes (g1934, g1937, g2415, g2539, g5858) were selected based on the copper binding site and signal peptide analysis results using the laccase gene selected from the F. velutipes var. lupinicola genome. The size of the laccase genes of F. velutipes var. lupinicola were 1,488 bp~1,662 bp. As a result of cDNA sequence analysis, 14 to 17 introns were identified in the laccase genes. The cleavage site predicted as the signal peptide of the laccase gene was found to be located between 20 bp and 34 bp from the N-terminus. In addition, separation and purification were performed to characterize the F. velutipes var. lupinicola laccases, and the optimal activity of the separated and purified proteins were analyzed by pH, temperature and time. Five bands with laccase activity were found from zymogram analysis. The optimal pH of the reaction was 5.5, the optimal temperature was found to be 40℃. Therefore, characterization of the laccase genes identified in this study should help in better understanding the biomass decomposition of F. velutipes var. lupinicola.

Definitive Closure of the Tracheoesophageal Puncture Site after Oncologic Laryngectomy: A Systematic Review and Meta-Analysis

  • Escandon, Joseph M.;Mohammad, Arbab;Mathews, Saumya;Bustos, Valeria P.;Santamaria, Eric;Ciudad, Pedro;Chen, Hung-Chi;Langstein, Howard N.;Manrique, Oscar J.
    • Archives of Plastic Surgery
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    • v.49 no.5
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    • pp.617-632
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    • 2022
  • Tracheoesophageal puncture (TEP) and voice prosthesis insertion following laryngectomy may fail to form an adequate seal. When spontaneous closure of the fistula tract does not occur after conservative measures, surgical closure is required. The purpose of this study was to summarize the available evidence on surgical methods for TEP site closure. A comprehensive search across PubMed, Web of Science, SCOPUS, and Cochrane was performed to identify studies describing surgical techniques, outcomes, and complications for TEP closure. We evaluated the rate of unsuccessful TEP closure after surgical management. A meta-analysis with a random-effect method was performed. Thirty-four studies reporting on 144 patients satisfied inclusion criteria. The overall incidence of an unsuccessful TEP surgical closure was 6% (95% confidence interval [CI] 1-13%). Subgroup analysis showed an unsuccessful TEP closure rate for silicone button of 8% (95% CI < 1-43%), 7% (95% CI < 1-34%) for dermal graft interposition, < 1% (95% CI < 1-37%) for radial forearm free flap, < 1% (95% CI < 1-52%) for ligation of the fistula, 17% (95% CI < 1-64%) for interposition of a deltopectoral flap, 9% (95% CI < 1-28%) for primary closure, and 2% (95% CI < 1-20%) for interposition of a sternocleidomastoid muscle flap. Critical assessment of the reconstructive modality should take into consideration previous history of surgery or radiotherapy. Nonirradiated fields and small defects may benefit from fistula excision and tracheal and esophageal multilayer closure. In cases of previous radiotherapy, local flaps or free tissue transfer yield high successful TEP closure rates. Depending on the defect size, sternocleidomastoid muscle flap or fasciocutaneous free flaps are optimal alternatives.

Skull Reconstruction with Custom Made Three-Dimensional Titanium Implant

  • Cho, Hyung Rok;Roh, Tae Suk;Shim, Kyu Won;Kim, Yong Oock;Lew, Dae Hyun;Yun, In Sik
    • Archives of Craniofacial Surgery
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    • v.16 no.1
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    • pp.11-16
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    • 2015
  • Background: Source material used to fill calvarial defects includes autologous bones and synthetic alternatives. While autologous bone is preferable to synthetic material, autologous reconstruction is not always feasible due to defect size, unacceptable donor-site morbidity, and other issues. Today, advanced three-dimensional (3D) printing techniques allow for fabrication of titanium implants customized to the exact need of individual patients with calvarial defects. In this report, we present three cases of calvarial reconstructions using 3D-printed porous titanium implants. Methods: From 2013 through 2014, three calvarial defects were repaired using custom-made 3D porous titanium implants. The defects were due either to traumatic subdural hematoma or to meningioma and were located in parieto-occipital, fronto-temporo-parietal, and parieto-temporal areas. The implants were prepared using individual 3D computed tomography (CT) data, Mimics software, and an electron beam melting machine. For each patient, several designs of the implant were evaluated against 3D-printed skull models. All three cases had a custom-made 3D porous titanium implant laid on the defect and rigid fixation was done with 8 mm screws. Results: The custom-made 3D implants fit each patient's skull defect precisely without any dead space. The operative site healed without any specific complications. Postoperative CTs revealed the implants to be in correct position. Conclusion: An autologous graft is not a feasible option in the reconstruction of large calvarial defects. Ideally, synthetic materials for calvarial reconstruction should be easily applicable, durable, and strong. In these aspects, a 3D titanium implant can be an optimal source material in calvarial reconstruction.

A Study on the Optimal Availability of the Government Institution Websites - Focused on the Capacity Evaluation and Management of the Main Page of the Website (행정기관 웹사이트의 최적의 가용성에 대한 연구 - 메인 화면의 용량 평가와 관리를 중심으로)

  • Moon, Hyung-Nam
    • Journal of Digital Convergence
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    • v.15 no.2
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    • pp.81-88
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    • 2017
  • I conducted a study on the capacity evaluation and management of the main homepage screen to improve the availability of government institutions. As a result of three times evaluating the size of the homepage main page of the major institutions, the capacity of the homepage of the institution was very enormous, and when there were many concurrent users, the server was easily loaded. Governmental management guidelines are needed to fundamentally solve these problems, with the periodic and ongoing homepage management of each institution. In the future, the web site management detailed checkpoints should be additionally established in the government web site installation and management guidelines, and the recommended checking items; homepage performance evaluation, lightening homepage capacity.

Treatment of fibrous dysplasia of the zygomaticomaxillary complex with radical resection and three-dimensional reconstruction with autologous calvarial bone graft

  • Ahn, Sung Jae;Hong, Jong Won;Kim, Yong Oock;Lew, Dae Hyun;Lee, Won Jai
    • Archives of Craniofacial Surgery
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    • v.19 no.3
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    • pp.200-204
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    • 2018
  • Fibrous dysplasia (FD) is a rare, benign bone disease with abnormal bone maturation and fibroblastic proliferation. Optimal treatment of zone 1 craniofacial FD is radical resection and reconstruction. To achieve of structural, aesthetic, and functional goals, we use three-dimensionally designed calvarial bone graft for reconstruction of zygomatic defect after radical resection of FD. The authors used a rapid-prototyping model for simulation surgery for radical resection and immediate reconstruction. Donor site was selected from parietal bone reflect shape, contour, and size of defect. Then radical resection of lesion and immediate reconstruction was performed as planned. Outcomes were assessed using clinical photographs and computed tomography scans. Successful reconstruction after radical resection was achieved by three-dimensional calvarial bone graft without complications. After a 12-month follow-up, sufficient bone thickness and symmetric soft tissue contour was well-maintained. By considering three-dimensional configuration of zygomaticomaxillary complex, the authors achieved satisfactory structural, aesthetic and functional outcomes without complications.

Effect of arbitrarily manipulated gap-graded granular particles on reinforcing foundation soil

  • Xin, Zhen H.;Moon, Jun H.;Kim, Li S.;Kim, Kab B.;Kim, Young U.
    • Geomechanics and Engineering
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    • v.17 no.5
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    • pp.439-444
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    • 2019
  • It is generally known that high strength soil is indicative of well-graded particle size distribution. However, there are some special cases of firm ground despite poor grade distribution, especially a specific gap-graded soil. Based on these discoveries, this study investigated the development of an additive of gap-graded soils designed to increase soil strength. This theoretical concept was used to calculate the mixed ratio required for optimal soil strength of the ground sample. The gap-graded aggregate was added according to Plato's polyhedral theory and subsequently calculated ratio and soil strength characteristics were then compared to characteristics of the original soil sample through various test results. In addition, the underground stress transfer rate was measured according to the test conditions. The test results showed that the ground settlement and stress limit thickness were reduced with the incorporation of gap-graded soil. Further field tests would confirm the reproducibility and reliability of the technology by using gap-graded soil to reinforce soft ground of a new construction site. Gap-graded soil has the potential to reduce the construction cost and time of construction compared to other reinforcing methods.

A Study on the Optimal Acquisition Site of STM Information Resources in KISTI (국내외 과학기술정보 수집규모의 최적화 연구 - 한국과학기술정보연구원을 대상으로 -)

  • 윤희윤
    • Journal of Korean Library and Information Science Society
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    • v.34 no.2
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    • pp.95-117
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    • 2003
  • In the context of the emerging knowledged-based economy, innovations and capacity of the national information system to collect disseminate, and preserve the most important information resources are becoming increasingly fundamental determinants of national prosperity and survival. It is essential that the scholarly or scientific communication system provides cost-effectiveness access to information in support of research and development in Korea. The KISTI is the first instance and last resort for access and preservation of scientific and technical information in Korea. The primary purpose of this study is to optimize an acquisition size of STM information resources for the KISTI, based on its SWOT analysis.

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Cloning and Expression of the Extracellular $\beta$-lactamase gene from streptomyces sp. SMF13 in streptomyces lividans

  • Rak, Choi-Sang;Lee, Kye-Joon
    • Korean Journal of Microbiology
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    • v.30 no.3
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    • pp.149-153
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    • 1992
  • Cloning of the gene encoding extracellular .betha.-lactamase from Streptomyces sp. SMF13 in a plasmid pIJ702 and expression of the gene in Streptomyces invidans were carried out. Optimal conditions for the formation of protoplasts of S.lividans and the regeneration of the protoplasts were evaluated. Streptomyces sp. SMF-13 was selected as a donor strain of .betha.-lactamase gene and totla DNA of the strain was partially digested with Sau3A I. DNA fragments ranged from 4kb to 10 kb were ligated to pIJ702 AT Bgl II site and then the ligated DNAs were transformed to the protoplasts of S, livivans. The transformation efficiency was $2 *10^{3}$ .$\mu$g DNA for the ligated DNA mixture. One colony among a thousand colonies regenerated showed extracellular .betha.-lactamase and the size of the inserted DNA fragment was estimated to be 3.94 kb. The .betha.-lactamase activity in the culture broth of the recombinant strain was maximum at 3 days culture to be 1.0 unit/ml.

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