• Title/Summary/Keyword: Opportunity Evaluation

Search Result 353, Processing Time 0.03 seconds

Anthocyanins: Targeting of Signaling Networks in Cancer Cells

  • Sehitoglu, Muserref Hilal;Farooqi, Ammad Ahmad;Qureshi, Muhammad Zahid;Butt, Ghazala;Aras, Aliye
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권5호
    • /
    • pp.2379-2381
    • /
    • 2014
  • It is becoming progressively more understandable that phytochemicals derived from edible plants have shown potential in modelling their interactions with their target proteins. Rapidly accumulating in-vitro and in- vivo evidence indicates that anthocyanins have anticancer activity in rodent models of cancer. More intriguingly, evaluation of bilberry anthocyanins as chemopreventive agents in twenty-five colorectal cancer patients has opened new window of opportunity in translating the findings from laboratory to clinic. Confluence of information suggests that anthocyanins treated cancer cells reveal up-regulation of tumor suppressor genes. There is a successive increase in the research-work in nutrigenomics and evidence has started to shed light on intracellular-signaling cascades as common molecular targets for anthocyanins. In this review we bring to l imelight how anthocyanins induced apoptosis in cancer cells via activation of extrinsic and intrinsic pathways.

공공부문 IT신기술 적용사업의 추진현황 평가와 정책적 시사점 (An Assessment and Policy Implication of Information Technology Convergence Programs in Korean Public Service Area)

  • 김성현
    • 한국IT서비스학회지
    • /
    • 제11권sup호
    • /
    • pp.1-16
    • /
    • 2012
  • Information technology is a useful strategic weapon that can create competitive advantage and new business opportunity by applying it in the organization' value chain. IT convergence can be understood as an attempt of industrial level IT adoption to facilitate the innovation of the industry and the birth of a new industry. This study provides the comprehensive review of the Korean government' three IT assimilation programs, ubiquitous technology diffusion program of the Ministry of Knowledge Economy, u-service program of the Ministry of Public Administration and Security, and u-Defence cooperation program of the Department of Defense. The analysis is done through the interpretation of the existing literature and the logic model. The result proposes inter-agency cooperation and building of new technology road-map in the planning stage, flexible management in the execution phase, and failure tolerant evaluation system. The proposal for developing competencies and institutional foundations for IT convergence also presented.

동적 균형상태를 중심으로 본 금강 지천의 참게자원 분석 (Applying Steady State Analysis to the Study of Mitten Crabs in Jichun, Kum River)

  • 전대욱;정회성
    • 한국시스템다이내믹스연구
    • /
    • 제11권1호
    • /
    • pp.27-57
    • /
    • 2010
  • This article deals with an ecological-economic analysis of the 'Pasture Project of Kum River', which is the farming plan of mitten crabs using Jichun, a stream of the River Kum where the natural propagation of mitten crabs are blocked because of the estuary dam constructed in 1990. Toward analyzing the ecological and economic effects of the crab releasing and harvesting activities in Jichun, a two-stage cohort model of population dynamics with cannibalistic behaviors and density restrictions in biomathematics is adopted, despite of the current infertility in Kum, considering the opportunity of establishing dam fishways in the near future. This study moreover presents a method of parameter estimation especially with assuming a steady state of the ecosystem, and performs various analyses such as the risk measurement of climate change and the economic value of such fishways.

  • PDF

경영성과평가를 위한 경제적 부가가치 활용에 관한 연구 (A Study on the Applying Economic Value Added for Evaluating Management Performance)

  • 조성훈;이상보;정민용
    • 산업경영시스템학회지
    • /
    • 제22권50호
    • /
    • pp.313-322
    • /
    • 1999
  • EVA(Economic Value Added) is a management performance evaluation tool that determines whether a business is earning more than its true cost of capital. Leading corporations like Coca-Cola, AT&T and Briggs&Stratton have set up EVA measurement systems throughout their organizations. EVA reflects opportunity cost of equity ignored in calculating accounting profit and emphasizes the efficiency of capital employed by measuring how much the manufacturing and selling activities produce the economic profit in excess of cost of gross capital. In this paper, we define the concept of EVA and present an example to show the usefulness of EVA.

  • PDF

Improving IPTV Forwarding Masechanism in IEEE 802.16j MMR Networks Based on Aggregation

  • Brahmia, Mohamed-El-Amine;Abouaissa, Abdelhafid;Lorenz, Pascal
    • ETRI Journal
    • /
    • 제35권2호
    • /
    • pp.234-244
    • /
    • 2013
  • Internet protocol television (IPTV) service depends on the network quality of service (QoS) and bandwidth of the broadband service provider. IEEE 802.16j mobile multihop relay Worldwide Interoperability for Microwave Access networks have the opportunity to offer high bandwidth capacity by introducing relay stations. However, to actually satisfy QoS requirements for offering IPTV services (HDTV, SDTV, Web TV, and mobile TV) for heterogeneous users' requests, providers must use a video server for each IPTV service type, which increases the network load, especially bandwidth consumption and forwarding time. In this paper, we present a solution for forwarding IPTV video streaming to diverse subscribers via an 802.16j broadband wireless access network. In particular, we propose a new multicast tree construction and aggregation mechanism based on the unique property of prime numbers. Performance evaluation results show that the proposed scheme reduces both bandwidth consumption and forwarding time.

농협 다문화여성대학의 교육과정에 대한 만족도 영향 요인 연구 (The impact of a positive change in life on the education satisfaction of the womens college for marriage immigrant women)

  • 양순미;한춘희;양점남
    • 농촌지도와개발
    • /
    • 제16권2호
    • /
    • pp.253-284
    • /
    • 2009
  • The purpose of this study is to examine a relative effect of the variables infecting on the education satisfaction of the Womens College for marriage immigrant women established by nonghyup to help improve the quality of life of theirs. By the hierarchical regression, a positive change in life through the education($\beta$=.28), a attitude of sustainable education participation($\beta$=.20), age ($\beta$=.21), whether or not in volunteer experience($\beta$=-.16) affected on the womens the education satisfaction significantly. But an effect of the variable of evaluation on the college education environment was not significant on it. It is conclude that the education for marriage immigrant women should be focused to enhance a adjustment capability of the women and to induce a change of life by supporting a sustainable education and a opportunity of affluent experience.

  • PDF

Prediction of Compressive Strength of Concretes Containing Silica Fume and Styrene-Butadiene Rubber (SBR) with a Mathematical Model

  • Shafieyzadeh, M.
    • International Journal of Concrete Structures and Materials
    • /
    • 제7권4호
    • /
    • pp.295-301
    • /
    • 2013
  • This paper deals with the interfacial effects of silica fume (SF) and styrene-butadiene rubber (SBR) on compressive strength of concrete. Analyzing the compressive strength results of 32 concrete mixes performed over two water-binder ratios (0.35, 0.45), four percentages replacement of SF (0, 5, 7.5, and 10 %) and four percentages of SBR (0, 5, 10, and 15 %) were investigated. The results of the experiments were showed that in 5 % of SBR, compressive strength rises slightly, but when the polymer/binder materials ratio increases, compressive strength of concrete decreases. A mathematical model based on Abrams' law has been proposed for evaluation strength of SF-SBR concretes. The proposed model provides the opportunity to predict the compressive strength based on time of curing in water (t), and water, SF and SBR to binder materials ratios that they are shown with (w/b), (s) and (p).This understanding model might serve as useful guides for commixture concrete admixtures containing of SF and SBR. The accuracy of the proposed model is investigated. Good agreements between them are observed.

조선업 협력업체의 안전관리 모델에 관한 연구 (A Study on Safety Management Model of Shipyard Industry Subcontractor)

  • 목연수;이동훈;장성록;고성석
    • 한국안전학회지
    • /
    • 제14권1호
    • /
    • pp.158-166
    • /
    • 1999
  • Due to the work characteristics of shipyard industry, subcontractors are essential and employees of them consist of 25% of the total employee. Problems of their safety management are as follows; - obscurity of safety management responsibility - flimsiness of subcontractor's safety awareness - absence of ability to develop safety techniques and to provide safety equipments - lack of opportunity of safety education The purpose of this study is modelling safety management system of shipyard industry subcontractors to reduce industrial accidents by employees of subcontractors. A phased model contained organization and work responsibility of related departments, safety management planning and evaluation system, safe work supporting system, safety education supporting system.

  • PDF

접착전단시험을 적용한 자가치료제의 접착특성 평가 (Evaluation of Bond Strength for Self-Healing Agents Using Modified Single Lap Shear Test)

  • 허광수;박희원;이종근;윤성호
    • 한국복합재료학회:학술대회논문집
    • /
    • 한국복합재료학회 2004년도 춘계학술발표대회 논문집
    • /
    • pp.266-269
    • /
    • 2004
  • In this study, bond strengths for the self-healing agents were evaluated through the modified lap shear test in order to suggest the optimal healing conditions for the repair of polymeric composites. The healing agents of DCPD, ENB, and their mixtures were activated with Grubbs' catalysts. According to the results, the mixture of DCPD and ENB gave better opportunity than DCPD only due to the rapid acivation with catalyst in view of the economic and practical use.

  • PDF

Enabling role of hybrid simulation across NEES in advancing earthquake engineering

  • Gomez, Daniel;Dyke, Shirley J.;Maghareh, Amin
    • Smart Structures and Systems
    • /
    • 제15권3호
    • /
    • pp.913-929
    • /
    • 2015
  • Hybrid simulation is increasingly being recognized as a powerful technique for laboratory testing. It offers the opportunity for global system evaluation of civil infrastructure systems subject to extreme dynamic loading, often with a significant reduction in time and cost. In this approach, a reference structure/system is partitioned into two or more substructures. The portion of the structural system designated as 'physical' or 'experimental' is tested in the laboratory, while other portions are replaced with a computational model. Many researchers have quite effectively used hybrid simulation (HS) and real-time hybrid simulation (RTHS) methods for examination and verification of existing and new design concepts and proposed structural systems or devices. This paper provides a detailed perspective of the enabling role that HS and RTHS methods have played in advancing the practice of earthquake engineering. Herein, our focus is on investigations related to earthquake engineering, those with CURATED data available in their entirety in the NEES Data Repository.