• Title/Summary/Keyword: Operating optimization

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Selection and optimization of nutritional risk screening tools for esophageal cancer patients in China

  • Dong, Wen;Liu, Xiguang;Zhu, Shunfang;Lu, Di;Cai, Kaican;Cai, Ruijun;Li, Qing;Zeng, Jingjing;Li, Mei
    • Nutrition Research and Practice
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    • v.14 no.1
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    • pp.20-24
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    • 2020
  • BACKGROUND/OBJECTIVES: Malnutrition has multiple impacts on surgical success, postoperative complications, duration of hospital stay, and costs, particularly for cancer patients. There are various nutrition risk screening tools available for clinical use. Herein, we aim to determine the most appropriate nutritional risk screening system for esophageal cancer (EC) patients in China. SUBJECTS/METHODS: In total, 138 EC patients were enrolled in this study and evaluated by experienced nurses using three different nutritional screening tools, the Nutrition Risk Screening 2002 tool (NRS2002), the Patient-generated Subjective Globe Assessment (PG-SGA), and the Nutrition Risk Index (NRI).We compared sensitivity, specificity, positive and negative likelihood ratios, and Youden index generated by each of the three screening tools. Finally, cut-off points for all three tools were re-defined to optimize and validate the best nutritional risk screening tool for assessing EC patients. RESULTS: Our data suggested that all three screening tools were 100% sensitive for EC patients, while the specificities were 44.4%, 2.96%, and 59.26% for NRS 2002, PG-SGA, and NRI, respectively. NRI had a higher positive likelihood ratio as well as a higher area under the receiver operating characteristic curve compared to those of NRS 2002 and PG-SGA; although, all three tools had null negative likelihood ratios. After adjusting the cut-off points, the specificity and accuracy for all tools were significantly improved, however, the NRI remained the most appropriate nutritional risk screening system for EC patients. CONCLUSIONS: The NRI is the most suitable (highest sensitivity and accuracy) nutritional risk screening tool for EC patients. The performance of the NRI can be significantly improved if the cut-off point is modified according to the results obtained using MedCalc software.

Optimization of Electrolysis Using Sacrificial Electrode for the Treatment of Electroless Nickel Plating Wastewater (희생전극을 이용한 무전해 니켈 도금 폐수의 전기분해처리 최적화)

  • Kim, Young-Shin;Jeon, Byeong-Han;Cho, Soon-Haing
    • Journal of Korean Society of Environmental Engineers
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    • v.37 no.4
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    • pp.204-209
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    • 2015
  • The effluent limit of nickel from electroplating wastewater has been strengthened from 5 mg/L to 3 mg/L from 2014. However, currently applied treatment process for nickel plating wastewater is unable to meet the effluent limit, most of the treatment concept conducted by treatment plant is dilution with other metal bearing wastewater. This can cause very significant impact to the environment of nickel contamination. With this connection, the feasibility test has been conducted with the use of electrolysis by using sacrificial electrodes. Experiments were conducted in synthetic and electroless nickel plating wastewater. Optimal condition of current density, pH were derived from the synthetic wastewater. It was found that the removal efficiency of nickel exceeded 94% at the operation condition of at pH 9 and the current density of $1{\sim}2mA/cm^2$. At this conditions, the iron sludge was generated very low amount. However, it was unsuccessful to meet the effluent limit by applying these treatment conditions to the real electroplating wastewater. This can be explained due to the matrix effect of other metals and anions contained real electroplating wastewater. From the result of further study, the optimal conditions for the real wastewater treatment were found out to be at pH 9, current density $6{\sim}7mA/cm^2$, for 5 minutes of operating time. At these conditions, 88% removal of nickel was achieved, which results the residual nickel concentration was below 3 mg/L.

OPTIMAL TRAJECTORY CORRECTION MANEUVER DESIGN USING THE B-PLANE TARGETING METHOD FOR FUTURE KOREAN MARS MISSIONS (B-평면 조준법을 이용한 화성 탐사선의 궤적 보정을 위한 최적의 기동 설계)

  • Song, Young-Joo;Park, Eun-Seo;Yoo, Sung-Moon;Park, Sang-Young;Choi, Kyu-Hong;Yoon, Jae-Cheol;Yim, Jo-Ryeong;Choi, Joon-Min;Kim, Byung-Kyo
    • Journal of Astronomy and Space Sciences
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    • v.22 no.4
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    • pp.451-462
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    • 2005
  • Optimal Trajectory Correction Maneuver (TCM) design algorithm has been developed using the B-plane targeting method for future Korean Mars missions. For every-mission phase, trajectory informations can also be obtained using this developed algorithms which are essential to design optimal TCM strategy. The information were computed under minimum requiring perturbations to design Mars missions. Spacecraft can not be reached at designed aim point because of unexpected trajectory errors, caused by many perturbations and errors due to operating impulsive maneuvers during the cruising phase of missions. To maintain spacecraft's appropriate trajectory and deliver it to the designed aim point, B-plane targeting techniques are needed. A software NPSOL is used to solve this optimization problem, with the performance index of minimizing total amount of TCM's magnitude. And also executing time of maneuvers on be controlled for the user defined maneuver number $(1\~5)$ of TCMs. The constraints, the Mars arrival B-plane boundary conditions, are formulated for the problem. Results of this work show the ability to design and analyze overall Mars missions, from the Earth launch phase to Mars arrival phase including capture orbit status for future Korean Mars missions

Optimization Strategies for Amine Regeneration Process with Heat-Stable Salt Removal Unit (열 안정성 염 제거장치를 고려한 아민 재생 공정 최적화 전략)

  • Lee, Jesung;Lim, Jonghun;Cho, Hyungtae;Kim, Junghwan
    • Applied Chemistry for Engineering
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    • v.31 no.5
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    • pp.575-580
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    • 2020
  • In this study, we simulated an amine regeneration process with heat-stable salts removal unit. We derived the optimal operating conditions considering the flow rate of waste, the removal rate of heat-stable salts, and the loss rate of MDEA (methyl diethanolamine). In the amine regeneration process that absorbs and removes acid gas, heat-stable salt impairs the absorption efficiency of process equipment and amine solution. An ion exchange resin method is to remove heat-stable salts through neutralization by using a strong base solution such as NaOH. The acid gas removal process was established using the Radfrac model, and the equilibrium constant of the reaction was calculated using Gibbs free energy. The removed amine solution is separated and flows to the heat-stable salts remover which is modeled by using the Rstoic model with neutralization reaction. Actual operation data and simulation results were compared and verified, and also a case study was conducted by adjusting the inflow mass of removal unit followed by suggesting optimal conditions.

Measurement of Plasma Parameters (Te and Ne) and Reactive Oxygen Species in Nonthermal Bioplasma Operating at Atmospheric Pressure

  • Choi, Eun Ha;Kim, Yong Hee;Kwon, Gi Chung;Choi, Jin Joo;Cho, Guang Sup;Uhm, Han Sup;Kim, Doyoung;Han, Yong Gyu;Suanpoot, Pradoong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.141-141
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    • 2013
  • We have generated the needle-typed nonthermal plasma jet by using an Ar gas flow at atmospheric pressure. Diagnostics of electron temperature anddensity is critical factors in optimization of the atmospheric plasma jet source in accordance with the gas flow rate. We have investigated the electron temperature and density of plasma jet by selecting the four metastable Ar emission lines based on the atmospheric collisional radiative model and radial profile characteristics of current density, respectively. The averaged electron temperature and electron density for this plasma jet are found to be ~1.6 eV and ~$3.2{\times}10^{12}cm^{-3}$, respectively, in this experiment. The densities of OH radical species inside the various bio-solutions are found to be higher by about 4~9 times than those on the surface when the argon bioplasma jet has been bombarded onto the bio-solution surface. The densities of the OH radicalspecies inside the DI water, DMEM, and PBS are measured to be about $4.3{\times}10^{16}cm^{-3}$, $2.2{\times}10^{16}cm^{-3}$, and $2.1{\times}10^{16}cm^{-3}$, respectively, at 2 mm downstream from the surface under optimized Ar gas flow 250 sccm.

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Nonlinearity Compensation of Electroabsorption Modulator by using Semiconductor Optical Amplifier (반도체 광증폭기를 이용한 전계흡수 광변조기 비선형성 보상)

  • Lee, Chang-Hyeon;Son, Seong-Il;Han, Sang-Guk
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.5
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    • pp.23-30
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    • 2000
  • To compensate the nonlinearity of electroabsorption modulator(EAM) resulting from its near exponential transfer function, a semiconductor optical amplifier(SOA) that has a log transfer function is used. Since the transfer function of SOA is inverse to that of EAM, the intermodulation distortion(IMD) of EAM can be reduced by cascading SOA to EAM. Also, the RF gain can be increased by the optical gain of SOA. For these reasons, spurious free dynamic range(SFDR) of EAM is enhanced by connecting SOA to EAM in series and operating in gain salutation region. To improve the nonlinearity compensation of EAM, the increased gain of SOA is required and the slope of gain saturation, the ratio of gain to input SOA power, needs to be steep. However, signal spontaneous beat noise that is the dominant system noise increases in proportion to the gain such that the SFDR of EAM is reduced. The higher the gain of SOA is, the more ASE is increased. Thus the noise level of system is increased and the following SFDR of EAM is decreased. The slope of gain saturation region and ASE of have trade-off relation and the optimization is achieved at 8㏈ optical gain. 9㏈ enhancement of SFDR of EAM is obtained. This scheme is easy to embody the linear EAM and the integration with three components (DFB-LD, EAM and SOA) offers many merits, such as low insertion loss, low chirping and low polarization sensitivity.

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Optimization for Phosphorus Remove by Loess Ball Using Chromobacterium (Chromobacterium을 이용한 황토볼에 의한 인산 제거를 위한 최적화)

  • Choi Du Bok;Lee Choon-Boem;Cha Wol-Suk
    • Journal of Life Science
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    • v.15 no.4 s.71
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    • pp.584-589
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    • 2005
  • To investigate factors affecting the removal of phosphorus from the practical wastewater in the F-STEP PROCESS using a loess ball and Chromobacterium WS 2-14, first, the loess ball size and calcining temperature, initial pH, initial phosphorus concentration, working temperature, and aeration were studied. A $2\~4mm$ of loess ball made at $960^{\circ}C$ of calcining temperature was the most suitable one for the removal of phosphorus. When the initial pH was increased from 3.0 to 6.0, the removal efficiency of phosphorus was increased. Especially, at 6.0 of initial pH, the maximum removal efficiency of phosphorus was $88.7\%$. The maximum removal efficiency of phosphorous was gained, 1.8mg/h when the initial concentration of phosphorous was 5.0mg/1. When the operating temperature was $30^{\circ}C$, the maximum removal efficiency of phosphorus was obtained. In the case of aeration, when it was increased from 0.5 to 5.0L/min, the removal efficiency of phosphorus was increased. On the other hand, above 7.0 L/min, the removal efficiency of phosphorus did not increased. Using the optimum operation conditions, pilot tests for the effective removal efficiency of phosphorus were carried out for 65 days. The average removal efficiency of phosphorus was $92.0\%$. The average removal efficiency of COD, BOD, and SS were 77.1, 74.2, and $86.4\%$, respectively. from the results, it can be concluded that F-STEP PROCESS using loess ball might be useful process for phosphorus removal.

Optimization of Supercritical Fluid Extraction of Tocotrienol from Grape Seed (초임계유체 추출을 이용한 포도씨 tocotrienol 추출조건 최적화)

  • Kim, Kyeong-Mi;Woo, Koan Sik;Hwang, In-Guk;Lee, Youn-Ri;Lee, Jun-Soo;Jeong, Heon-Sang
    • Korean Journal of Food Science and Technology
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    • v.41 no.1
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    • pp.37-41
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    • 2009
  • In this study, supercritical carbon dioxide extraction (SFE) was utilized for the extraction of tocotrienol from grape seeds. The optimal conditions for vitamin E and tocotrienol extraction were determined via response surface methodology (RSM). Central composite design was utilized to assess the effects of oven temperature (30-$50^{\circ}C$, X1), operating pressure (17-25 MPa, X2), and extraction time (1-5 hr, X3) of supercritical fluid extraction. Vitamin E and tocotrienol contents were 8.65 mg/100 g and 7.88 mg/100 g at $40^{\circ}C$, 20MPa and 5 hr, respectively. The predicted extraction condition was validated via actual experimentation. The predicted extraction conditions were $40^{\circ}C$, 3.8 hr, and 20.7MPa. The vitamin E and tocotrienol contents under these conditions were 8.20 mg/100 g and 7.42 mg/100 g, respectively. The vitamin E and tocotrienol contents of solvent extraction with hexane were 8.18 mg/100 g and 7.24 mg/100 g, respectively.

Bioleaching of Heavy Metals from Shooting Range Soil Using a Sulfur-Oxidizing Bacteria Acidithiobacillus thiooxidans (황산화균 Acidithiobacillus thiooxidans를 이용한 사격장 토양 내 중금속 용출)

  • Han, Hyeop-Jo;Lee, Jong-Un;Ko, Myoung-Soo;Choi, Nag-Choul;Kwon, Young-Ho;Kim, Byeong-Kyu;Chon, Hyo-Taek
    • Economic and Environmental Geology
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    • v.42 no.5
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    • pp.457-469
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    • 2009
  • Applicability of bioleaching techniques using a sulfur-oxidizing bacteria, Acidithiobacillus thiooxidans, for remediation of shooting range soil contaminated with toxic heavy metals was investigated. The effects of sulfur concentration, the amount of bacterial inoculum and operation temperature on the efficiency of heavy metal solubilization were examined as well. As sulfur concentration and the amount of bacterial inoculum increased, the solubilization efficiency slightly increased; however, significant decrease of heavy metal extraction was observed with no addition of sulfur or bacterial inoculum. Bacteria solubilized the higher amount of heavy metals at $26^{\circ}C$ than $4^{\circ}C$. Lead showed the highest removal amount from the contaminated soil but the lowest removal efficiency when compared with Zn, Cu and Cr. It was likely due to formation of insoluble $PbSO_{4(s)}$ as precipitate or colloidal suspension. Sequential extraction of the microbially treated soil revealed that the proportion of readily extractable phases of Zn, Cu and Cr increased by bacterial leaching, and thus additional treatment or optimization of operation conditions such as leaching time were required for safe reuse of the soil. Bioleaching appeared to be a useful strategy for remediation of shooting range soil contaminated with heavy metals, and various operating conditions including concentration of sulfur input, inoculum volume of bacteria, and operation temperature exerted significant influence on bioleaching efficiency.

Optimal Method of Radon Analysis in Groundwater using Ultra Low-Level Liquid Scintillation Counter (극 저준위 액체섬광계수기를 이용한 지하수 중 라돈($^{222}Rn$) 측정법 연구)

  • Kim Yong-Je;Cho Soo-Young;Yoon Yoon-Yeol;Lee Kil-Yong
    • Journal of Soil and Groundwater Environment
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    • v.11 no.5
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    • pp.59-66
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    • 2006
  • Optimal method of radon analysis in groundwater was studied using ultra low-level liquid scintillation counter (ULLLSC) which is well known as an analytical instrument for analyzing the alpha and beta radionuclides in environmental materials. Optimization of pulse shape analyzer (PSA) in operating the LSC was performed with $^{241}Am\;and\;^{90}Sr/^{90}Y$ as well as $^{226}Ra$ Also, the chemical quenching of scintillation generation and the color quenching of the generated photon to photomultiplier tubes (PMT) were determined their effects not only to decrease the analytical efficiency but also to change the optimal PSA level and background due to high ion contents of groundwaters. The optimal PSA level was shown in the range of 90 to 110 with less than 5% error. The effects of high ion contents in groundwater for the analytical efficiency show within 10% error from the different ion contents. The chloroform as a quenching agent was used to determine the analytical efficiency with the different amount, showing that the efficiency decreases 20% using the 2% of chloroform.