• 한국정보통신학회논문지
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• 제20권6호
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• pp.1183-1188
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• 2016

키넥트 센서 버전 2는 컴퓨터 비전과 엑스 박스와 같은 엔유아이 인터페이스로 마이크로소프트에서 출시한 카메라의 일종이다. 이는 높은 프레임 속도로 컬러 영상과 깊이 영상, 오디오 입력 및 스켈레톤 데이터를 취득 할 수 있다. 이러한 다양한 타입의 데이터 정보를 제공해 주기 때문에 이것은 다른 범위의 연구자들을 위한 리소스가 된다. 본 논문에서는 깊이 이미지를 사용하여 우리는 키넥트 범위내에서 특정 영역을 감시하는 시스템을 제시한다. 타켓 영역은 깊이의 최소, 최대 값의 크기에 따라서 그 공간을 모니터링 할 수 있다. 컴퓨터 비전 라이브러리 (Emgu CV)를 사용해서 만약 어떤 오브젝트가 타겟 영역에서 검출된다면 그것을 추적하고 키넥트 카메라는 RGB 이미지를 데이터베이스 서버에 전송한다. 따라서 안드로이드 플랫폼 기반 모바일 애플리케이션을 통해 키넥트 타켓 지역에서 수상한 움직임이 감지되었음을 사용자에게 통지하고 그 장면의 RGB 영상을 표시하기 위해 개발되었다. 사용자는 모니터링 영역 또는 제한 구역과 관련된 다른 경우에서 가치 있는 물건의 대해 최선의 방법으로 반응하고 실시간 통지를 얻는다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2499-2506
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• 2016

Background: Gastric cancer (GC) is the second leading cause of cancer-related death worldwide. Several environmental, genetic and epigenetic factors have been suggested to have a role in GC development. Epigenetic mechanisms like histone changes and promoter hyper-methylation are now being increasingly studied. Associations between methylation of many gene promoters with the risk of gastric cancer have been investigated worldwide. Such aberrant methylation may result in silencing of specific genes related to cell cycling, cell adhesion, apoptosis and DNA repair. Thus this molecular mechanism might have a key role in proliferation and migration of cancerous cells. Materials and Methods: In this review article we included studies conducted on DNA methylation and gastric cancer in Iranian populations. Using Science direct, Pubmed/PMC, Springer, Wiley online library and SciELO databases, all published data until 31 January 2016 were gathered. We also searched Science direct data base for similar investigations around the world to make a comparison between Iran and other countries. Results: By searching these databases, we found that the association between methylation of seven gene promoters and gastric cancer had been studied in Iran until 31 January 2016. These genes were p16, hLMH1, E-cadherin, CTLA4, $THR{\beta}$, mir9 and APC. Searching in science direct database also showed that 92 articles had been published around the world till January 2016. Our investigation revealed that despite the importance of GC and its high prevalence in Iran, the methylation status of only a few gene promoters has been studied so far. More studies with higher sample numbers are needed to reveal the relation of methylation status of gene promoters to gastric cancer in Iran. Conclusions: Further studies will be helpful in identifying associations of DNA methylation in candidate genes with gastric cancer risk in Iranian populations.

• Clinical and Experimental Pediatrics
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• 제63권3호
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• pp.79-87
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• 2020

Inherited platelet disorders (IPDs), which manifest as primary hemostasis defects, often underlie abnormal bleeding and a family history of thrombocytopenia, bone marrow failure, hematologic malignancies, undefined mucocutaneous bleeding disorder, or congenital bony defects. Wide heterogeneity in IPD types with regard to the presence or absence of thrombocytopenia, platelet dysfunction, bone marrow failure, and dysmegakaryopoiesis is observed in patients. The individual processes involved in platelet production and hemostasis are genetically controlled; to date, mutations of more than 50 genes involved in various platelet biogenesis steps have been implicated in IPDs. Representative IPDs resulting from defects in specific pathways, such as thrombopoietin/MPL signaling; transcriptional regulation; granule formation, trafficking, and secretion; proplatelet formation; cytoskeleton regulation; and transmembrane glycoprotein signaling are reviewed, and the underlying gene mutations are discussed based on the National Center for Biotechnology Information database and Online Mendelian Inheritance in Man accession number. Further, the status and prevalence of genetically confirmed IPDs in Korea are explored based on searches of the PubMed and KoreaMed databases. IPDs are congenital bleeding disorders that can be dangerous due to unexpected bleeding and require genetic counseling for family members and descendants. Therefore, the pediatrician should be suspicious and aware of IPDs and perform the appropriate tests if the patient has unexpected bleeding. However, all IPDs are extremely rare; thus, the domestic incidences of IPDs are unclear and their diagnosis is difficult. Diagnostic confirmation or differential diagnoses of IPDs are challenging, time-consuming, and expensive, and patients are frequently misdiagnosed. Comprehensive molecular characterization and classification of these disorders should enable accurate and precise diagnosis and facilitate improved patient management.

• 정보기술과데이타베이스저널
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• 제7권2호
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• pp.87-100
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• 2000

전통적 오프라인 비즈니스에 비하여 e-Business의 특징 중 하나는 고객충성도 개념이 급격한 변화를 겪고 있다는 점이다. 본 연구는 e-Business의 핵심 기반인 정보시스템의 품질이 고객충성도에 어떠한 영향을 미치는지를 분석하였다. 즉, 정보시스템 품질을 시스템 품질, 정보 컨텐츠 품질, 서비스 품질 3개 독립변수로 설정하고, 이러한 변수들이 종속변수인 고객충성도에 미치는 영향을 실증적으로 검증하였다. e-Business 중 가장 활성화되고 있는 사이버증권 분야를 조사대상으로 하였으며, 온라인 설문조사와 방문조사에 의하여 8,265명에 달하는 사이버 고객 데이터가 수집되었다. 데이터 분석 결과, 3개 독립변수 모두가 고객충성 도에 긍정적인 영향을 미치는 것으로 나타났으며, 그 중에서 시스템 품질이 가장 큰 영향력을 지니고 있는 것으로 분석되었다.

• Asian review of World Histories
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• 제4권1호
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• pp.3-34
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• 2016

This introduction is both a statement of a research problem and an account of the first research results for its solution. As more historical databases come online and overlap in coverage, we need to discuss the two main issues that prevent 'big' results from emerging so far. Firstly, historical data are seen by computer science people as unstructured, that is, historical records cannot be easily decomposed into unambiguous fields, like in population (birth and death records) and taxation data. Secondly, machine-learning tools developed for structured data cannot be applied as they are for historical research. We propose a complex network, narrative-driven approach to mining historical databases. In such a time-integrated network obtained by overlaying records from historical databases, the nodes are actors, while thelinks are actions. In the case study that we present (the world as seen from Venice, 1205-1533), the actors are governments, while the actions are limited to war, trade, and treaty to keep the case study tractable. We then identify key periods, key events, and hence key actors, key locations through a time-resolved examination of the actions. This tool allows historians to deal with historical data issues (e.g., source provenance identification, event validation, trade-conflict-diplomacy relationships, etc.). On a higher level, this automatic extraction of key narratives from a historical database allows historians to formulate hypotheses on the courses of history, and also allow them to test these hypotheses in other actions or in additional data sets. Our vision is that this narrative-driven analysis of historical data can lead to the development of multiple scale agent-based models, which can be simulated on a computer to generate ensembles of counterfactual histories that would deepen our understanding of how our actual history developed the way it did. The generation of such narratives, automatically and in a scalable way, will revolutionize the practice of history as a discipline, because historical knowledge, that is the treasure of human experiences (i.e. the heritage of the world), will become what might be inherited by machine learning algorithms and used in smart cities to highlight and explain present ties and illustrate potential future scenarios and visionarios.

• ALGAE
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• 제35권3호
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• pp.293-301
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• 2020

The applications of DNA barcoding have a wide range of uses, such as in taxonomic studies to help elucidate cryptic species and phylogenetic relationships and analyzing environmental samples for biodiversity monitoring and conservation assessments of species. After obtaining the DNA barcode sequences, sequence similarity-based homology analysis is commonly used. This means that the obtained barcode sequences are compared to the DNA barcode reference databases. This bioinformatic analysis necessarily implies that the overall quantity and quality of the reference databases must be stringently monitored to not have an adverse impact on the accuracy of species identification. With the development of next-generation sequencing techniques, a noticeably large number of DNA barcode sequences have been produced and are stored in online databases, but their degree of validity, accuracy, and reliability have not been extensively investigated. In this study, we investigated the extent to which the amount and types of erroneous barcode sequences were deposited in publicly accessible databases. Over 4.1 million sequences were investigated in three largescale DNA barcode databases (NCBI GenBank, Barcode of Life Data System [BOLD], and Protist Ribosomal Reference database [PR2]) for four major DNA barcodes (cytochrome c oxidase subunit 1 [COI], internal transcribed spacer [ITS], ribulose bisphosphate carboxylase large chain [rbcL], and 18S ribosomal RNA [18S rRNA]); approximately 2% of erroneous barcode sequences were found and their taxonomic distributions were uneven. Consequently, our present findings provide compelling evidence of data quality problems along with insufficient and unreliable annotation of taxonomic data in DNA barcode databases. Therefore, we suggest that if ambiguous taxa are presented during barcoding analysis, further validation with other DNA barcode loci or morphological characters should be mandated.

• Journal of Korean Neurosurgical Society
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• 제61권4호
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• pp.467-473
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• 2018

Objective : The aim of this study was to determine outcome of ischemic stroke patients in the anterior circulation treated with endovascular treatment (EVT) with intravenous thrombolysis (IVT) versus EVT alone group. Methods : A systemic literature review was performed using online database from January 2004 to January 2017. Primary outcomes were successful recanalization seen on finial angiography and good outcome at three months. Secondary outcomes were mortality and the development of symptomatic intracranial hemorrhage (S-ICH) after the procedure. A fixed effect model was used when heterogeneity was less than 50%. Egger's regression test was used to assess publication bias. Results : Five studies were included for final analysis. Between EVT with IVT and EVT alone group, successful recanalization (odds ratio [OR] 1.467, p=0.216), good clinical outcome at three months (OR 1.199, p=0.385), mortality (OR 0.776, p=0.371), and S-ICH (OR 1.820, p=0.280) did not differ significantly. Egger's regression intercept with 95% confidence interval (CI) was 1.99 (95% CI -2.91 to 6.89) in successful recanalization and -0.27 (95% CI -6.35 to 5.80) in good clinical outcome, respectively. Conclusion : The two treatment modalities, EVT with IVT and EVT alone, could be comparable in treating acute anterior circulation stroke. Studies to find specific beneficiary group for EVT alone, without primary IVT, are needed further.

• 한국도서관정보학회지
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• 제21권
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• pp.253-289
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• 1994

The purpose of this study is about the search pattern of LINNET (Library Information Network System) OPAC users by transaction log, maintained by POSTECH(Pohang University of Science and Technology) Central Library, to provide feedback information of OPAC system design. The results of this study are as follows. First, for the period of this analysis, there were totally 11, 218 log-ins, 40, 627 transaction logs and 3.62 retrievals per a log-in. Title keyword was the most frequently used, but accession number, bibliographic control number or call number was very infrequently used. Second, 47.02% of OPAC, searches resulted in zero retrievals. Bibliographic control number was the least successful search. User displayed 2.01% full information and 64.27% local information per full information. Third, special or advanced retrieval features are very infrequently used. Only 22.67% of the searches used right truncation and 0.71% used the qualifier. Only 1 boolean operator was used in every 22 retrievals. The most frequently used operator is 'and (&)' with title keywords. But 'bibliographical control number (N) and accessionnumber (R) are not used at all with any operators. The causes of search failure are as follows. 1. The item was not used in the database. (15, 764 times : 79.42%). 2. The wrong search key was used. (3, 761 times : 18.95%) 3. The senseless string (garbage) was entered. (324 times : 1.63%) On the basis of these results, some recommendations are suggested to improve the search success rate as follows. First, a n.0, ppropriate user education and online help function let users retrieve LINNET OPAC more efficiently. Second, several corrections of retrieval software will decrease the search failure rate. Third, system offers right truncation by default to every search term. This methods will increase success rate but should considered carefully. By a n.0, pplying this method, the number of hit can be overnumbered, and system overhead can be occurred. Fourth, system offers special boolean operator by default to every keyword retrieval when user enters more than two words at a time. Fifth, system assists searchers to overcome the wrong typing of selecting key by automatic korean/english mode change.

• 한국도서관정보학회지
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• 제43권4호
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• pp.69-88
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• 2012

본 연구는 부산시 공공도서관의 운영현황 분석을 통한 향후 발전방향을 도모하기 위한 것이다. 연구결과, 첫째, 일반적 이용현황은 대부분 소설대출이나 개인공부를 목적으로 방문하고, 도서관관련 정보나 행사는 오프라인을 통한 검색이 이루어지고 있었다. 둘째, 온라인서비스사용기간이나 웹사이트 방문빈도는 낮았으나, 컴퓨터 설치확대와 홈엑세스가 가능하도록 하는 온라인DB의 기술개선을 요구하였다. 셋째, 공공도서관에 대한 지역사회의 서비스중요성은 매우 중요하게 인식하고 있었다. 도서관 운영지표 중 지역서비스의 중요성(m=3.86)은 높게 나타났다. 그러나 참고데스크(m=2.87), 체크아웃데스크(m=2.41), 컴퓨터가용성(m=2.47) 및 최신자료유용성(m=2.64)에서는 평균값이 3.0에 미치지 못한 것으로 나타남으로써 공공도서관의 운영정책이 실질이용자의 요구사항을 제대로 반영하지 못한 것으로 나타났다.

• 한국정보과학회논문지:소프트웨어및응용
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• 제31권6호
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• pp.808-816
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• 2004

본 논문에서는 다중 특징 결합과 유사도 공간을 이용한 실제적인 온라인 얼굴 검증 시스템을 구현하는 방법을 제안한다. 얼굴 검증에서의 주요 쟁점은 다양한 얼굴 형상 변화의 처리이다. 이러한 변화는 단지 한가지 특징만으로는 해결되기 어렵다. 따라서 얼굴 형상에 있어서의 다양한 변화를 처리하기 위해서 상호보완적인 특징들의 결합이 필요하다. 이러한 관점에서 우리는 다중 주성분 분석과 에지 분포에 기반 한 특징 추출 방법을 제안한다. 이러한 특징들은 다수의 간단한 유사도 측정 방법들로 형성된 새로운 intra-person/extra-person 유사도 공간으로 사상되고, 최종적으로 Support Vector Machine에 의해 평가된다. 실제적인 대용량 데이터 베이스로 실험한 결과, equal error rate 0.029의 결과를 나타내었고, 이는 많은 실제 응용제품에도 충분히 팩용 가능한 수준이다.