• 제목/요약/키워드: One-pot reaction

검색결과 157건 처리시간 0.023초

A Simple and Efficient One-Pot Three-Component Synthesis of Propargylamines Using Bismuth (III) Chloride

  • Teimouri, Abbas;Chermahini, Alireza Najafi;Narimani, M.
    • Bulletin of the Korean Chemical Society
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    • 제33권5호
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    • pp.1556-1560
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    • 2012
  • A simple highly versatile and efficient method has been developed for the three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in the presence of a catalytic amount of $BiCl_3$. The advantages of methods are high yield, mild reaction conditions, no environmental pollution and easy work up procedure.

Retention of Configuration; Mechanism Studies on the Reaction of Chlorosulfonyl Isocyanate with Ethers

  • Kim, Ji-Duck;Jung, Young-Hoon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.242.2-243
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    • 2003
  • We have developed the novel one-pot synthetic method for regioselective N-protected amines, carbamates as a protective group of amines, through the reaction of various ethers with chlorosulfonyl isocyanate (CSJ). This synthetic method provides a simple and convenient alternative for the formation of carbamates, such as -NHMoc, -NHPoc. -NHCbz, -NHPnz, -NHTroc and -NHAloc, by varying the alkyl moiety of ethers. (omitted)

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Magnesium Bistrifluoromethanesulfonimide Catalyzed Three-component Synthesis of Protected Homoallylic Amines

  • Wang, Hongshe;Zeng, June
    • Bulletin of the Korean Chemical Society
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    • 제32권7호
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    • pp.2203-2206
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    • 2011
  • A mild and efficient procedure has been developed for the one-pot, three-component reaction of aldehydes, benzyl carbamate and allyltrimethylsilane in the presence of 3 mol % of magnesium bistrifluoromethanesulfonimide at room temperature to afford the corresponding protected homoallylic amines in high yields.