• Journal of Gifted/Talented Education
• /
• v.25 no.2
• /
• pp.217-236
• /
• 2015

The purpose of this study was to investigate factors that affected achievement of socially succeeded people, and to draw ways to improve gifted education. To do this, we interviewed 60 achievers. The interview was administrated as semi-structured deep interview about 6 areas - education, major, family and parent, personal relationship, leisure time activity, achievement and motivation of success. The results showed that achievers were active students during their school days. They thought differentiated education and student-centered lessons are important. Many achievers answered they do not have any personal mentee, and decision of majors and education should be matched with the perception of one's potential and interest. Exercises, music, and reading books were strongly suggested as leisure time activities, and the key inner factors for success were curiosity and self-confidence. Beneficiaries of gifted education perceived their experience of gifted education had a positive influence on their achievement. Based on the these results, ways to improve gifted education were discussed.

• Journal of Korea Multimedia Society
• /
• v.3 no.5
• /
• pp.526-534
• /
• 2000

There have been many researches on the 3D graphic accelerator for high speed by needs of CAD/CAM,3D modeling, virtual reality or medical image. In this paper, an SIMD processor architecture for 3D graphic accelerator is proposed in order to improve the processing time of the 3D graphics, and a parallel Phong shading algorithm is presented to estimate performance of the proposed architecture. The proposed SIMD processor architecture for 3D graphic accelerator consists of PCI local bus interface, 16 Processing Elements (PE's), and Park's multi-access memory system (NAMS) that has 17 memory modules. A serial algorithm for Phong shading is modified for the architecture and the main key is to divide a polygon into $4\times{4}$ squares. And, for processing a square, 4 PE's are regarded as a PE Grou logically. Since MAMS can support block access type with interval 1, it is possible that 4 PE Groups process a square at a time. In consequence, 16 pixels are processed simultaneously. The proposed SIMD processor architecture is simulated by CADENCE Verilog-XL that is a package for the hardware simulation. With the same simulated results as that of the serial algorithm, the speed enhancement by the parallel algorithm to the serial one is 5.68.

• Archives of Pharmacal Research
• /
• v.27 no.9
• /
• pp.961-967
• /
• 2004

The development of an antibody labeling method with $^{99m}$Tc is important for cancer imaging. Most bifunctional chelate methods for $^{99m}$Tc labeling of antibody incorporate a $^{99m}$Tc chelator through a linkage to lysine residue. In the present study, a novel site-specific $^{99m}$Tc labeling method at carbohydrate side chain in the Fc region of 2 antibodies (T101 and rabbit anti-human serum albumin antibody (RPAb)) using dihydrazinophthalazine (DHZ) which has 2 hydrazino groups was developed. The antibodies were oxidized with sodium periodate to pro-duce aldehyde on the Fc region. Then, one hydrazine group of DHZ was conjugated with an aldehyde group of antibody through the formation of a hydrazone. The other hydrazine group was used for labeling with $^{99m}$Tc. The number of conjugated DHZ was 1.7 per antibody. $^{99m}$Tc labeling efficiency was 46-85％ for T101 and 67∼87％ for RPAb. Indirect labeling with DHZ conjugated antibodies showed higher stability than direct labeling with reduced antibodies. High immunoreactivities were conserved for both indirectly and directly labeled antibodies. A biodistribution study found high blood activity related to directly labeled T1 01 at early time point as well as low liver activity due to indirectly labeled T101 at later time point. However, these findings do not affect practical use. No significantly different biodistribution was observed in the other organs. The research concluded that DHZ can be used as a site-specific bifunctional chelating agent for labeling antibody with $^{99m}$Tc. Moreover, $^{99m}$Tc labeled antibody via DHZ was found to have excellent chemical and biological properties for nuclear medicine imaging.edicine imaging.

• Korean Journal of Construction Engineering and Management
• /
• v.14 no.1
• /
• pp.124-132
• /
• 2013

An influx of the population to the city has soared due to industrialization. As times go by, cities become densely populated so Korean government started to construct a number of buildings including apartment housings. Because they have become functionally, structurally, esthetically deteriorated over the past two decades. some improvements are needed. There are mainly two ways to improve old buildings: remodeling and reconstruction. Between the two, the first one is more popular as it is less time-consuming and more eco-friendly. Demolition work comes first for both of them and it should not give negative effects since it is regarded as a CP(Critical path) in the overall process. For this reason, a thorough construction management must be done. The reality, however, demolition is managed by the construction manager's experiences and decisions. If the key factor of demolition which is the planning of manpower and machine equipment, is determined by unscientific and subjective judgments, its period and risk also will increase. In particular, eco-friendly demolition can be more risky because it's been rarely conducted. Therefore, scientific and objective ways of demolition management are needed. In this context, this paper aims at analyzing productivity in each process of demolition focusing on manpower and machinery equipment which are the main parts of demolition assuming that the demands of eco-friendly remodeling demolition projects will be increasing. At the same time, by estimating working period through the output, this paper would be helpful to set up the plans for overall project in earlier stage.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.41 no.6
• /
• pp.209-220
• /
• 2004

The main feature of H.264 standard against conventional video standards is the high coding efficiency and the network friendliness. In spite of these outstanding features, it is not easy to implement H.264 codec as a real-time system due to its high requirement of memory bandwidth and intensive computation. Although the variable block size motion compensation using multiple reference frames is one of the key coding tools to bring about its main performance gain, it demands substantial computational complexity due to SAD (Sum of Absolute Difference) calculation among all possible combinations of coding modes to find the best motion vector. For speedup of motion estimation process, therefore, this paper proposes fast algorithms for both integer-pel and fractional-pel motion search. Since many conventional fast integer-pel motion estimation algorithms are not suitable for H.264 having variable motion block sizes, we propose the motion field adaptive search using the hierarchical block structure based on the diamond search applicable to variable motion block sizes. Besides, we also propose fast fractional-pel motion search using small diamond search centered by predictive motion vector based on statistical characteristic of motion vector.

• Journal of Broadcast Engineering
• /
• v.13 no.6
• /
• pp.941-950
• /
• 2008

The quality of projector output image is influenced by the surrounding conditions such as the shape and color of screen, and environmental light. Therefore, techniques that ensure desirable image quality, regardless of such surrounding conditions, have been in demand and are being steadily developed. Among the techniques, radiometric compensation is a representative one. In general, radiometric compensation is achieved by measuring the color of the screen and environmental light based on an analysis of camera image of projector output image and then adjusting the color of projector input image in a pixel-wise manner. This process is not time-consuming for small sizes of images but the speed of the process drops linearly with respect to image size. In large sizes of images, therefore, reducing the time required for performing the process becomes a critical problem. Therefore, this paper proposes a fast radiometric compensation method. The method uses color filters for eliminating the color mixing between projector and camera because the speed of radiometric compensation depends mainly on measuring color mixing between projector and camera. By using color filters, there is no need to measure the color mixing. Through experiments, the proposed method improved the compensation speed by 44 percent while maintaining the projector output image quality. This method is expected to be a key technique for widespread use of projectors for large-scale and high-quality display.

• Molecules and Cells
• /
• v.37 no.7
• /
• pp.547-553
• /
• 2014

Glioblastoma multiforme (GBM) is one of the most common brain malignancies and has a very poor prognosis. Recent evidence suggests that the presence of cancer stem cells (CSC) in GBM and the rare CSC subpopulation that is resistant to chemotherapy may be responsible for the treatment failure and unfavorable prognosis of GBM. A garlic-derived compound, Z-ajoene, has shown a range of biological activities, including anti-proliferative effects on several cancers. Here, we demonstrated for the first time that Z-ajoene specifically inhibits the growth of the GBM CSC population. CSC sphere-forming inhibition was achieved at a concentration that did not exhibit a cytotoxic effect in regular cell culture conditions. The specificity of this inhibitory effect on the CSC population was confirmed by detecting CSC cell surface marker CD133 expression and biochemical marker ALDH activity. In addition, stem cell-related mRNA profiling and real-time PCR revealed the differential expression of CSC-specific genes, including Notch, Wnt, and Hedgehog, upon treatment with Z-ajoene. A proteomic approach, i.e., reverse-phase protein array (RPPA) and Western blot analysis, showed decreased SMAD4, p-AKT, 14.3.3 and FOXO3A expression. The protein interaction map (http://string-db.org/) of the identified molecules suggested that the AKT, ERK/p38 and $TGF{\beta}$ signaling pathways are key mediators of Z-ajoene's action, which affects the transcriptional network that includes FOXO3A. These biological and bioinformatic analyses collectively demonstrate that Z-ajoene is a potential candidate for the treatment of GBM by specifically targeting GBM CSCs. We also show how this systemic approach strengthens the identification of new therapeutic agents that target CSCs.

• The Journal of the Korea Contents Association
• /
• v.12 no.5
• /
• pp.103-112
• /
• 2012

This paper is based on the perspective that the YTN Science, a science channel in Korea which plays a key role in the popularization of science, is suffering from low viewing ratings, insufficient content, and shortage of production. First, this study employs an exploratory method to identify current status of programming and operation of the Korean science channel along with its promotional strategy. Second, it aims to conduct an analysis on the science channels, specifically some major programs, of other nations including the U.S. (Discovery Channel, National Geographic Channel), United Kingdom (BBC Knowledge), Japan (Science Channel), and China (CCTV 10), seeking the possibility to apply and combine them afterward to the Korean TV channels specialized in science. A number of implications are derived from our diagnosis of present situation and analysis of abroad cases, and this helps us suggest the content development and promotional strategies as follows: First, due to the rising need for change in the programming strategy to enhance the value of the content, it is required to rearrange the programming in terms of the target audience and the viewer lifestyle, adopt a new strategy for building up the viewers' watching habit through 'stripping', and place strategic programs in prime-time. Second, as for the specific schemes of content production and application, it is recommended to establish a dual strategy in creating the content (one for conveying knowledge, the other for delivering fun), plan and use a representative character of the program, select scientific and technological topics with more Korean backgrounds, attempt strategic ties with SNS, deepen and diversify the material for programs, and implement a strategy to boost the OSMU. Finally, with regard to the promotional strategy, a constructive proposal may include raising channel awareness through science-related events and live broadcasting, performing promotional strategies by way of expanding to printed media like magazine and book publications, and intensifying online and mobile promotional strategy.

• Geophysics and Geophysical Exploration
• /
• v.8 no.2
• /
• pp.156-162
• /
• 2005

Particularly in research related to seawater intrusion the change of fluid electrical conductivity is one of major concerns, and effective monitoring can help to optimize a water pumping performance in coastal areas. Special considerations should be given to the mounting of sensors at proper depth during the monitoring design since the vertical distribution of fluid electrical conductivity is sensitive to the characteristics of seawater intrusion zone. This tells us the multi-channel electrical conductivity monitoring is of paramount consequence. It, however, is a rare event when this approach becomes routinely available in that commonly used commercial stand-alone type sensors are very expensive and inadequate for a long term monitoring of electrical conductivity or water level due to their restricted storage and difficulty of real-time control. For this reason, we have developed a real-time monitoring system that could meet these requirements. This system is user friendly, cost-effective, and easy to control measurement parameters - sampling interval, acquisition range, and others. And this devised system has been utilized for the electrical conductivity monitoring in boreholes, Yeonggwang-gun, Korea. Monitoring has been consecutively executed for 24 hours, and the responses of electrical conductivity at some channels have been regularly increased or decreased while pumping up water. It, with well logging data implemented before/after pumping water, verifies that electrical conductivity changes in the specified depths originate from fluid movements through sand layer or permeable fractured rock. Eventually, the multi-channel electrical conductivity monitoring system makes an effective key to secure groundwater resources in coastal areas.

• Pediatric Infection and Vaccine
• /
• v.26 no.3
• /
• pp.199-205
• /
• 2019

Enteroviral infections are common in neonates. One important infection pathway is vertical transmission from an infected mother to her neonate. Here, we report the early detection and successful treatment of a vertically transmitted fulminant enteroviral infection associated with myocarditis and hepatitis. The patient had a sudden onset of high fever on the fourth day of life and developed severe, rapidly progressing symptoms of disseminated intravascular coagulopathy (DIC), hepatitis, and myocarditis accompanied by tachyarrhythmia. As it was the peak season for enteroviral infections and both the mother and the patient's 36-month-old sibling had a high fever around the time of delivery, we suspected an enteroviral infection. Thus, we initiated prompt evaluation of enteroviral infection, as well as close observation and intensive care of the neonate. We strongly recommend evaluation for the possibility of vertical enterovirus infection in neonates when the mother is suspected of having a viral infection (e.g., high fever and negative results from bacterial infectious studies) around the time of delivery and when the neonate shows some early symptoms of infectious diseases such as thrombocytopenia, DIC, hepatitis, and myocarditis. Early detection of enteroviral infections and prompt implementation of proper treatment are key to reduce the risk of complications and mortality associated with enteroviral infections in neonates.