• 한국운동역학회지
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• 제21권2호
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• pp.223-230
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• 2011

The purpose of this study was to analysis the effect of form and hardness of outsoles on the motion of the lower extremity joints and on foot pressure during gait. The subjects were 15 women(mean age, $48.5{\pm}2.4$ years), who had no serious musculoskeletal, coordination, balance or joint/ligament problems within 1 year prior to the study. The pelvic tilt, joint angles at the lower extremities and the vertical ground reaction force(GRF) were compared during gait with 3 types of shoes (A, B, C) by using one-way repeated ANOVA(p<.05). During gait, the peak tilt angle and the range of motion(ROM) of the ankle and knee joints were found to be significantly different among the 3 types of shoes. The type C shoes showed a significantly lower mean second maximum vertical GRF than types A and B. The curved outsoles of type C shoes, which had a form and hardness different from those of A and B, was designed strategically for walking shoes to provide stability to the Additionally, type C induced the dispersion of eccentric pressure and made the center of pressure roll over to the center line of the foot.

• Journal of Microbiology and Biotechnology
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• 제27권1호
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• pp.49-56
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• 2017

In the human airway, mucus exists to protect the respiratory system as a primary barrier of the innate immune system. However, hyperexpressed mucus limits airflow, resulting in a decrease of lung function. Among more than 20 mucin family members, MUC5AC and MUC5B are major glycoproteins in human airway mucus. The epidermal growth factor receptor (EGFR) signaling pathway is one of the mechanisms of these mucins expression and specificity protein-1 (Sp1) transcription factor is the downstream signal of this pathway, playing pivotal roles in mucin expression. Even though there are some drugs for treating mucus hypersecretion, no drug has proven effects on humans. We found that the flavonoid tilianin regulated MUC5AC expression and also inhibited Sp1 phosphorylation. In this study, we investigated how tilianin would modulate EGFR signaling and regulate mucin production. In conclusion, tilianin inhibited MUC5AC expression mediated via modulating the EGFR-MEK-ERK-Sp1 signaling pathway in NCI-H292 human airway epithelial cells. This study may provide the basis for the novel treatment of mucus hypersecretion.

• 한국콘텐츠학회논문지
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• 제9권10호
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• pp.176-185
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• 2009

본 연구는 골밀도검사를 받은 폐경 후 여성들을 대상으로 신체특징을 조사한 다음 혈압측정과 혈액검사를 실시하였으며, 총 653명을 대상으로 하였다. 통계 분석은 SPSS for Windows 프로그램(version 12.0)을 사용하였고, ANOVA 및 카이제곱으로 관련성을 비교분석하였으며, 변인 예측을 위해 선형회귀분석방법을 실시하여 다음과 같은 결론을 얻었다. 골밀도와 심혈관위험인자 중 신장, 체중, 체질량지수는 T-score와 유의한 양의 관계가 나타났고 (p<0.001), 연령, 수축기혈압, 이완기혈압, 총콜레스테롤, 고밀도지단백콜레스테롤, 중성지방, 혈당에서 T-score와 유의한 음의 관계가 있는 것으로 나타났으며(p<0.001), 골밀도에 가장 큰 영향을 미치는 변인은 체중(18.7%)으로 나타났다. 골밀도와 심혈관위험인자의 관계는 모두에서 유의한 관련성이 나타났다. 따라서 인구의 노령화와 함께 여성들에게서 골다공증 문제가 더욱 중요시되고 있는 추세이므로 골다공증의 발생기전을 규명하고 효율적인 예방 전략을 수립하기 위한 체계적인 연구의 시도가 계속되어야 할 것으로 사료된다.

• 디지털콘텐츠학회 논문지
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• 제18권7호
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• pp.1303-1312
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• 2017

이데올로기들은 영화를 구성하는 다양한 요소들에 의해 표출된다. 그 중 하나가 의상이다. 본 연구는 웨스 앤더슨의 영화 작품속 의상에 표출된 유니폼의 조형적 특징과 이미지의 분석에 연구의 목적을 두고 있다. 이를 위해 논자는 2010년 이후에 제작된 웨스 앤더슨의 작품들 중 <문라이즈 킹덤>(2012), <그랜드 부다페스트 호텔>(2014)의 두 편을 연구 대상으로 선정하였다. 본 연구를 통해 유니폼과 이데올로기 양자간의 인과성과 그것이 갖는 상징적 의미를 파악할 수 있었다. 영화에 등장한 유니폼은 인물들의 직업이나 역할을 드러내기 위한 목적에서 나아가 소속감, 독립성, 권위, 사명감, 정체성과 동일체성, 자부심 등을 표출하고 있는데, 이 중 두 영화에 공통적으로 나타난 가치는 소속감, 독립성과 권위, 사명감 등이다.

• Journal of Chest Surgery
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• 제28권6호
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• pp.533-541
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• 1995

We recently developed a new model of moving actuator type totally implantable artificial heart[TIAH , based on the reverse position of the aortic and pulmonary conduits. This concept was proposed by one of surgeons in our team[Joon-Ryang Rho, M.D. to facilitate anatomical fitting of TIAHs. The moving actuator type electromechanical TIAH consisted of the left and right blood sacs, and the moving actuator including a motor. The inverted umbrella type polyurethane valves were used in the blood pumps. The aortic conduit was positioned anterior to the pulmonary conduit, which was the opposite relation to the conventional configuration of other total artificial hearts. We also adapted slip-in connectors for the aortic and pulmonary conduits. Two sheep , weighing 60-69 kg, were used for implantation. After small cervical incision and trans-sternal bilateral thoracotomy, cardiopulmonary bypass [CPB was administered using an American Optical 5-head pump and a membrane oxygenator[Univox-IC, Bentley . The anterior and posterior vena cavae were drained separately for venous return. An arterial return cannula was inserted into the right common carotid artery. During CPB, almost all of the ventricular myocardium was excised down to the atrioventricular groove and the artificial heart was implanted. We achieved 3-day survival in the first sheep and 2-day survival in the second. The day after operation the first sheep was successfully extubated and the second sheep was weaned from a respirator with good condition. After extubation, the first sheep walked around in the cage and fed herself. Serial laboratory and hemodynamic examinations were done during the experiments. In both sheep, pulmonary dysfunction was gradually developed, which was accompanied by acute renal failure. The animals were sacrificed and autopsy was done. Unexpected pregnnacy was incidentally found in both sheep. To our knowledge this is the first report of significant survival cases in the orthotopic implantation of electric TIAH using sheep.

• 한국전자통신학회논문지
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• 제6권2호
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• pp.256-261
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• 2011

본 논문에서는 친환경 하이브리드 자동차의 핵심부품중 배터리 전압을 모니터하는 CVM(Cell Voltage Monitoring) 동작에서 모니터링된 배터리 전압을 디지털 데이터로 변환시키는 A/D (Analog to Digital) 컨버터의 설계 및 제작결과를 소개한다. CVM에 적정한 A/D컨버터는 중속동작 및 고분해능의 동작이 필요하여, SAR(Successive Approximate Register) typed A/D 컨버터 사용을 제안하였고, Magna 0.6um 40V 공정을 이용하여 10bits 분해능을 갖도록 설계 및 제작하였으며, 측정결과 FSR(Full Scale Range) 5V 전구간에서 ${\pm}1$ LSB Accuracy의 선형성을 확보하여, CVM 구현에 유용함을 나타내었다.

• 천문학회보
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• 제41권2호
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• pp.47.1-47.1
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• 2016

We present a preliminary result of search for CO molecular outflows toward a sample of 68 candidate Very Low Luminosity Objects (VeLLOs; Lint ${\leq}0.1L_{\odot}$) to help to understand their physical properties. The sources have been identified using the data at IR to radio wavelengths by M. Kim et al. 2016 toward nearby star-forming regions in the Gould belt. These sources were observed in rotational transitions 2-1 and 3-2 of $^{12}CO$, $^{13}CO$, and $C^{18}O$ molecules with SRAO, CSO, JCMT, and ASTE telescopes. In the beginning of our survey we made a single pointing observation in $^{12}CO$ 2-1 or 3-2 lines for our sample, identifying 53 sources as potential outflow candidates from their line wing features. We made full or partial mapping observations for these candidates with the same lines, finding 33 sources with bipolar or one-sided outflow features. Out of these 33 sources, 6 VeLLOs are previously known sources to have their outflows and 27 VeLLOs are found to be new outflow sources identified from this study. We estimated outflow properties with corrections for excitation temperature, optical depth, and inclination. Their outflow forces range from $8.7{\times}10^{-10}$ to $6.0{\times}10^{-5}M_{\odot}\;km\;s^{-1}yr^{-1}$ with a median value of $3.6{\times}10^{-7}M_{\odot}\;km\;s^{-1}yr^{-1}$, indicating that most of the VeLLOs are less powerful than those for protostars. Their accretion luminosities vary from $9.7{\times}10^{-9}$ to $166L_{\odot}$ with a median value of $0.004L_{\odot}$, implying that most VeLLOs have larger ratios of the accretion luminosity to the internal luminosity but a significant number of VeLLOs have smaller ratios. This result suggests that many of the VeLLOs can be explained with episodic accretion but a significant number of VeLLOs cannot.

• Asia pacific journal of information systems
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• 제16권4호
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• pp.49-70
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• 2006

In recent, Open markets are booming up rapidly. Open markets are one of the online marketplaces which mainly concentrated on spot transactions of commodities, and are differentiated from integrated internet shopping stores with market participants, trading rules and so on. This study investigated on factors affecting satisfaction with and preference on open markets by comparing open markets with integrated internet shopping stores, and aimed to figure out the reasons why open markets are growing up so rapidly and to forecast the future of open markets. To investigate the factors affecting buyers' satisfaction with and preference on internet shopping channel. I extracted several factors through literature reviews. The factors include the pros (cost saving and time saving), the cons (security concerns and privacy concerns), and decision making support suggested by Simon's research as well. Then, I constructed research model and related research hypotheses. To verify research hypotheses, I conducted field survey targeting on online buyers and analyzed research data using structural equation model. According to data analysis result, open markets have competitive advantages over integrated internet shopping stores with respect to cost saving, time saving, and decision making support. However, online buyers are still concerning privacy issues within open markets. In summary, buyers are considering that open markets are cheaper, faster, and more efficient internet shopping channel, compared with integrated internet shopping stores. However, open markets are required to dedicate to lessen buyers' privacy concerns to rebirth as more satisfying and preferable internet shopping channel and to prosper in the future.

• 생명과학회지
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• 제15권1호
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• pp.94-99
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• 2005

충청남도 목천과 충청북도 오창 근교의 토양으로부터 망간을 산화하는 64 집락을 분리하고 이 중 망간 산화능이 가장 우수한 한 균주를 최종 선별하여 생리, 생화학적 특성을 조사하고, 16S rRNA 염기 서열분석 등을 통하여 동정한 결과 최종 선별된 균주는 Aeromonas sp. MN44로 확인되었다. 최종 선별된 Aeromenas sp. MN44는 lactose를 제외한 여러 당들은 이용하지 못하였으며, 중금속내성은 lithium과 manganese에 대해서는 mg/ml 단위의 높은 농도까지 중금속 내성을 가지고 있었지만 cadmium에는 전혀 내성을 나타내지 않았다. 또 kanamycin, chloramphenicol, ampicillin, tetracycline, spectinomycin등 조사한 모든 항생제에 대해 전혀 내성을 갖지 않았다. Aeromonas sp. MN44가 생성하는 망간산화물질의 최적 pH는 pH 7.4로 확인되었으며, 이 균이 생성하는 망간 산화 factor는 proteinase K와 가열처리에 의해 저해되는 단백질이고, ammonium sulfate 침전과 ion exchange chromatography 그리고 gel filtration의 단계를 통해 부분 정제한 망간 산화 factor의 분자량은 약 113 kDa로 확인되었다.

• 한국식품과학회지
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• 제25권6호
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• pp.643-648
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• 1993

표준온도 상당시간을 이용하여 규칙적인 온도변화 조건에서 식품의 품질변화를 간편하게 예측하는 근사식의 유효성을 밝히기 위하여, 비등온 가속조건 및 상온저장 조건에서 Sucrose 가수분해속도를 측정한 설험자료로 비교, 분석을 분석하였다. 정속가열 (定速加熱) 가속(加速)실험을 통해 구한 sucrose의 가수분해 반응은 1차 반응이고, 활성화에너지는 25.84kcal/mol이었으며, 반응속도상수는 pH가 감소함에 따라 직선적으로 증가하였다. 하루 동안의 온도변화를 sine wave 형태 온도변화로 가정하고 하루 동안에 일어난 품질변화를 표준온도 $T_{ref}$에서 몇일 동안에 일어난 변화에 상당하는가를 의미하는 표준온도 상당시간 $T_{eq.i}$를 이용하여 품질변화를 근사적으로 간단히 예측하는 방법을 제안하였다. Sucrose 액체 모델 시스템을 sine wave 형태의 규칙적인 온도변화 조건에서의 가속 가수분해실험 결과와 $T_{eq.i}$를 이용하여 품질변화를 computer simulation한 결과, 실험값과 예측값과의 상관계수는 0.99로서 잘 일치하였으므로 표준온도상당시간을 이용한 예측 모델의 유효함을 확인하였다. 뿐만 아니라 sucrose 모델 시스템을 실제 상온 저장한 실험결과와 계절적 온도변화를 computer simulation하여 예측한 값과는 상관계수가 0.92로서 잘 일치하였다.