• The korean journal of orthodontics
• /
• v.42 no.1
• /
• pp.47-54
• /
• 2012

Objective: To determine and compare the frequency distribution of various arch shapes in ethnic Malays and Malaysian Aborigines in Peninsular Malaysia and to investigate the morphological differences of arch form between these two ethnic groups. Methods: We examined 120 ethnic Malay study models (60 maxillary, 60 mandibular) and 129 Malaysian Aboriginal study models (66 maxillary, 63 mandibular). We marked 18 buccal tips and incisor line angles on each model, and digitized them using 2-dimensional coordinate system. Dental arches were classified as square, ovoid, or tapered by printing the scanned images and superimposing Orthoform arch templates on them. Results: The most common maxillary arch shape in both ethnic groups was ovoid, as was the most common mandibular arch shape among ethnic Malay females. The rarest arch shape was square. Chi-square tests, indicated that only the distribution of the mandibular arch shape was significantly different between groups (p = 0.040). However, when compared using independent t-tests, there was no difference in the mean value of arch width between groups. Arch shape distribution was not different between genders of either ethnic group, except for the mandibular arch of ethnic Malays. Conclusions: Ethnic Malays and Malaysian Aborigines have similar dental arch dimensions and shapes.

• Korean Journal of Agricultural Science
• /
• v.38 no.3
• /
• pp.493-504
• /
• 2011

This study was carried out to safety evaluation, the practical application and improvement of design method of the agricultural reservoir due to raising embankments. Also, it was to compare and analyze the pore water pressure (PWP), seepage (leakage) quantity and piping phenomenon according to high water table and rapid drawdown. The seepage analysis by finite element analysis was used for steady state and transient condition. The pore water pressure distribution for steady state and transient condition showed positive(+) PWP on the upstream slope, it was gradually changed negative(-) PWP on the downstream slope. The PWP in the core ranged from 100 ~ -33 kPa, the seepage line in the incline-type core suddenly decreased towards the lower levels from the higher levels. The PWP according to rapid drawdown is remained in the vicinity of the upstream slope, therefore, it is investigated to be in an unstable state by the slope stability analysis. The PWP after raising embankments showed smaller than in the before raising embankments. It was likely to be the piping phenomenon because the gradients in the before raising embankments showed largely at downstream slope, and the stability for piping in the after raising embankments increased stable state. The seepage quantity per 1 day and the leakage per 100m for the steady state and transient condition appeared to be safe against the piping. It reduced slightly regardless of the transient condition before the raising embankments and it decreased largely about 2.4 times in the early days after the raising embankments.

• Korean Journal of Applied Biomechanics
• /
• v.28 no.3
• /
• pp.181-185
• /
• 2018

Objective: The purpose of this study was to investigate the effect of types of drive-in initial steps in basketball on technical factors, to provide basic information for the enhancement of basketball skill. Method: Ten men (age: $24.70{\pm}2.26years$; height: $181.00{\pm}5.72cm$; weight: $75.70{\pm}8.23kg$; career length: $10.00{\pm}3.59years$), each with a career length of over five years and no history of injury to the lower extremities within the prior six months, participated in this study. They were asked to perform four types of drive-in movements at $35{\sim}60^{\circ}$, wearing their own shoes, after running from a start line 5 m away and catching a basketball passed by an expert passer. The drive-in movements were measured by eight infrared cameras (Oqus 300, Qualisys, Sweden). Collected raw data were used to calculate total initial step time, displacement, velocity, center of mass (COM) height, and COM velocity. Results: Total initial step displacement and velocity of cross drive-ins (JC, SC) were greater than that of direct drive-ins (JD, SD; p < .05). COM velocity of cross drive-ins (JC, SC) was also greater than that of direct drive-ins (JD, SD; p < .05). Conclusion: Our results indicated that cross drive-ins, regardless of stop step type, are more effective than direct drive-ins. This is because cross drive-ins are technically bold due to less influence from walking violations and double dribble rules in basketball. However, using one-sided movement is too difficult to play in competitive game; therefore, basketball players should develop the ability to choose appropriate movement frequency.

• Interdisciplinary Bio Central
• /
• v.3 no.2
• /
• pp.7.1-7.6
• /
• 2011

Background: Published manuscripts are the main source of biological knowledge. Since the manual examination is almost impossible due to the huge volume of literature data (approximately 19 million abstracts in PubMed), intelligent text mining systems are of great utility for knowledge discovery. However, most of current text mining tools have limited applicability because of i) providing abstract-based search rather than sentence-based search, ii) improper use or lack of ontology terms, iii) the design to be used for specific subjects, or iv) slow response time that hampers web services and real time applications. Results: We introduce an advanced text mining system called PubMine that supports intelligent knowledge discovery based on diverse bio-ontologies. PubMine improves query accuracy and flexibility with advanced search capabilities of fuzzy search, wildcard search, proximity search, range search, and the Boolean combinations. Furthermore, PubMine allows users to extract multi-dimensional relationships between genes, diseases, and chemical compounds by using OLAP (On-Line Analytical Processing) techniques. The HUGO gene symbols and the MeSH ontology for diseases, chemical compounds, and anatomy have been included in the current version of PubMine, which is freely available at http://pubmine.kobic.re.kr. Conclusions: PubMine is a unique bio-text mining system that provides flexible searches and analysis of biological entity relationships. We believe that PubMine would serve as a key bioinformatics utility due to its rapid response to enable web services for community and to the flexibility to accommodate general ontology.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.10
• /
• pp.5131-5136
• /
• 2012

Cancer is one of the major health problems worldwide and its current treatments have a number of undesired adverse side effects. Natural compounds may reduce these. Currently, a few plant products are being used to treat cancer. In this study, goniothalamin, a natural occurring styryl-lactone extracted from Goniothalamus macrophyllus, was investigated for cytotoxic properties against cervical cancer (HeLa), breast carcinoma (MCF-7) and colon cancer (HT29) cells as well as normal mouse fibroblast (3T3) using MTT assay. Fluorescence microscopy showed that GTN is able to induce apoptosis in HeLa cells in a time dependent manner. Flow cytometry further revealed HeLa cells treated with GTN to be arrested in the S phase. Phosphatidyl serine properties present during apoptosis enable early detection of the apoptosis in the cells. Using annexin V/PI double staining it could be shown that GTN induces early apoptosis on HeLa cells after 24, 48 and 72 h. It could be concluded that goniothalamin showing a promising cytotoxicity effect against several cancer cell lines including cervical cancer cells (HeLa) with apoptosis as the mode of cell death induced on HeLa cells by Goniothalamin was.

• The Journal of the Korea Contents Association
• /
• v.7 no.11
• /
• pp.248-257
• /
• 2007

With the advance of information technology, e-learning is widely used. However, due to the lack of human computer interaction, e-mentoring or blended learning are adopted to complement the drawbacks of e-learning these days. One of the common purposes for adopting these tools is to enhance the interaction level by using bbs or blogs based on e-communities. If the cooperative learning contents management tools that share learners' knowledge in e-learning are provided, interactivity and educational effects can be enhanced. In this paper, a tree-based learning contents construction tool and a community-based cooperative learning contents construction tools that can share the learners' knowledge are proposed. Also, we analyze the influencing factors to the learners by using the proposed tools.

• Korean Journal of Clinical Pharmacy
• /
• v.18 no.1
• /
• pp.50-59
• /
• 2008

Objective: The aim for this article was to evaluate and to clarify the current opinions of the registered pharmacists concerning their recognition and adoption rates about introducing the preceptorship into the clinical pharmacy internship and clerkship. Methods: A 25-question-questionnaire was developed and pilot tested. For 40 days of survey by both on-line and on site, 90 over 240 (37.5%) registered pharmacists responded and the data were analyzed with comparison to the groups working in community and hospital pharmacies. Results: The overall answers were affirmative and the respondents were very interested in the application of the clinical preceptorship to the pharmacy educational and to their clinical settings. Moreover, the qualification level and the implementation methods were proposed in detail. Conclusion: Although ninety pharmacists showed their views differently, most of the respondents regarded the preceptorship as an adequate training system for the pharmacy students as well as junior pharmacists at the time of initiation of the new 6-year pharmacy education system in Korea.

• Journal of Agricultural Extension & Community Development
• /
• v.20 no.1
• /
• pp.41-69
• /
• 2013

The analytical result indicates that their sociological variables including education background, age and marital status, and job satisfaction factors including employment term, job title, compensation, organization, promotion, colleague, job transfer have a significant impact on the quality of their life. This means that their job satisfaction affects the quality of life. In other words, it is necessary to create an environment which can offset their complaints about job environment and conditions and furthermore, generate a sense of pride and a rewarding experience. The study suggests transparent, fair HR system and continuous training and management in consideration of employees' qualification, experience and interest to boost a sense of pride and social recognition and increase the level of job satisfaction as a result. In line with this approach, their dedication to bringing positive changes in local communities is also essential.

• Journal of the Economic Geographical Society of Korea
• /
• v.11 no.3
• /
• pp.334-349
• /
• 2008

In this study, the network formation process of personal actors in industries for the elderly was analyzed. This process is applied to the knowledge creation model of the SECI (Nonaka-Takeuchi learning cycle), that is socialization, externalization, combination, internalization. There are some kinds of opportunities to interact in these industries in the forms of field survey teams to overseas, some seminars and symposiums, many kinds of meetings, education and training programs, trade fairs and on-line forums. These palces(ba) - originating ba, interacting ba, cyber ba, exercising ba - played great roles in the formation of personal actor networks. Personal actors had opportunities to interconnect with distant actors through those places(ba). In the spatial perspective, personal actors could make face-to-face contact and build trust through temporary geographical proximity or temporary clusters with the help of personal mobility. Relations in the virtual spaces such as the Internet community did much toward building personal networks.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.29 no.3
• /
• pp.273-280
• /
• 2015

In this study, we used the mixture made from the Rice bran 45 ㎏, Dendropanax 5 ㎏, the sugar of the 10% of the total weight, and the enzyme of the 0.1% of the total weight. After the mixture were fermented for 90 days under 20 $^{\circ}C$, we measured the cell viability and the inhibition rate of the melanin biosynthesis, the activity of tyrosinase and superoxide dismutase (SOD) in malignant melanoma, B16F10 cells, in order to survey the whitening effect and the mechanism of the effects on the sample. As a result, the samples significantly suppressed the cell viability of B16F10 in more than 500 ${{\mu}g}$/㎖ and significantly inhibited the generation of melanin induced by ${\alpha}$-MSH in more than 1,000 ${{\mu}g}$/㎖. Sample decreased the activity of tyrosinase while increased the activity of SOD in dose dependent manner. Therefore, we considered that the fermentation extract made from a Rice bran and Dendropanax will be able to produce high value-added products, if used as a commercial.