• The Journal of Internal Korean Medicine
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• v.43 no.2
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• pp.152-158
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• 2022

Objective: This study addresses a case of fibromyalgia with insomnia and dry mouth. Methods: A patient diagnosed with fibromyalgia was treated with Korean medicine including herbal therapy with Guibiondam-tang-gagam, acupuncture, pharmacopuncture, moxibustion, and chuna for 16 days. To evaluate the therapeutic effects, sleeping hours, time taken to fall asleep, and surprise on waking were assessed, and a numeric rating scale (NRS) was used to monitor dry mouth. Results: After treatment, the patient's sleeping hours increased, time taken to fall asleep decreased, and the patient woke up surprised less often. The NRS score for dry mouth also decreased. Conclusion: These results suggest that Korean medicine therapies with Guibiondam-tang-gagam have a beneficial effect on insomnia and dry mouth as additional symptoms of fibromyalgia.

• Korean Journal of Oriental Medicine
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• v.13 no.3
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• pp.151-156
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• 2007

Sagunja-tang(Sijunzi-tang) has been traditionally prescribed as a restorative. The present study was undertaken to determine the possible toxic effects of Sagunja-tang on SD rats. In this study, we investigated the subacute toxicity of water-extracted Sagunja-tang(Sijunzi-tang) on SD rats. Twenty rats were orally adiministered Sagunja-tang for 28 days at a dose of 0 mg/kg(control group) or 1500mg/kg(treated group), respectively. All of subjects was survived. No significant difference in abnormal clinical signs, related to hematological values, serum biochemical values, water and feed intake, coagulation time, autopsy analysis, organ weight, tissue microscopically, funduscopy, urine intake and urinalysis, was detected. Compared with the control group, we could not find any subacute toxic alteration in treated group (1500mg/kg) for 28 days. This result suggests that Sagunja-tang(Sijunzi-tang). a herbal medicine prescription, is a safe prescription to body.

• The Journal of Korean Medicine
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• v.31 no.2
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• pp.167-176
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• 2010

Objectives: The purpose of this study was to report the effect of Kamitongkyung-tang on adenomyosis. Methods: Three women who were diagnosed with adenomyosis were enrolled in this study. They were supposed to have blood aggregation, so received oriental treatments to decrease blood aggregation and promote blood flow. They took Kamitongkyung-tang internally 3 times a day and were taken acupuncture therapy 3 times a week during about 3 months. Results: The most common symptoms of adenomyosis were menorrhagia and dysmenorrhea. After the treatment, symptoms of adenomyosis decreased and ultrasonography showed good results. Conclusion: These clinical cases indicated that Kamitongkyung-tang was effective in the treatment of adenomyosis. More clinical data and studies are needed about the treatment of adenomyosis.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.15 no.2
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• pp.169-174
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• 2011

Objectives: Seven Emotions consist of Joy(喜), Anger(怒), Anxiety(憂), Thought(思), Sorrow(悲), Fear(恐), Fright(驚). If Seven Emotions are excessive, their extreme mental stimulations cause physical illness. The aim of the research is to make a proposal on the concept of Seven Emotions by a statistical comparison between guibi-tang questionnaire and health related questionnaires. Methods: We studied the similarities among three factors of guibi-tang questionnaire and three health related questionnaires(subjective symptoms of fatigue test, beck depression inventory, state-trait anxiety inventory, etc.) using multidimensional scaling. Results and Conclusions: 1. Physical-Emotion Dimension and Chronic-Acute Dimension were labelled in two-dimensional solution. 2. Seven Emotions and Fatigue have a high correlation. 3. Seven Emotions and Trait-Anxiety have a high correlation.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.2
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• pp.114-129
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• 2023

Objectives: This case report aims to report the clinical effectiveness of the combination treatment of Korean medicine on abnormal uterine bleeding. Methods: The patients who diagnosed with abnormal uterine bleeding complained of menometrorrhagia, dizziness, lower abdomen pain and general weakness. They received combination treatment of Korean medicine during hospitalization. The treatments included Guibi-tang-gamibang, acupuncture, moxibustion and pharmaco-acupuncture. Results: After the treatment, abnormal uterine bleeding stopped and the clinical symptoms such as dizziness, lower abdomen pain and general weakness were improved. Conclusions: This case report shows that the combination treatment of Korean medicine with Guibi-tang-gamibang may be effective for treating abnormal uterine bleeding.

• Journal of Acupuncture Research
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• v.18 no.1
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• pp.29-39
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• 2001

Purpose : It has been reported that Oyo-Tang has an effect on allergic asthma clinically. In order to investigate the herbal acupuncture solution of the Oyo-Tang on allergic asthma, the Oyo-Tang herbal-acupuncture(OTHA) was applied on BL13 and ST36 of allergic asthma model of the rats. Methods : Then the concentration of serum IgE and the ratio of CD4+ and CD8+ T-cells in peripheral blood were measured and compared with control group. Results : The results obtained as follows; 1. The concentration of serum IgE was decreased significantly in both of the OTHA on BL13 group and on ST36 group as compared to control group. 2. The ratio of CD4+ and CD8+ T-cells in peripheral blood was not different statistically between the normal, the control, the OTHA on BL13 and the OTHA on ST36 group.

• The Journal of Internal Korean Medicine
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• v.23 no.2
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• pp.298-305
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• 2002

These cases were performed on the bases of clinical consideration about patients who had Methicillin-Resistant Staphylococcus aureus(MRSA) infection. One patient was a 67-years-old women who had sequela of inter cranial hemorrhage & inter ventricular hemorrhage, hypertention, urinary tract infection and pneumonia. Clinical symptoms were intermittent fever, sputum, Lt. side hemiparesis and dysphagia. She was chronic, repeated infection state. It could be regarded as "unpreparedness of the spirit which animates and controls the universe; 正氣虛", the oriental term which indicates a condition of chronic disease or general weakness. According to the oriental medicine principle, oriental medicine was taken such as Wunggunza-tang(六君子湯) and the patient had taken a turn for the better. After 3 months, MRSA infection diappeared. The other patient was a 43-years-old women who had Both brain stem infarction, Lt. cerebellar infarction, hypercholesterolemia, urinary tract infection and pneumonia, Clinical symptoms were quadriplegia, dysphagia(levin tube insert state), aphasia, respiration disorder(tracheostomy cannular keep state) and sputum. She was chronic, repeated infection state. It could be regarded as "unpreparedness of spleen energy, unpreparedness of both energy and blood; 脾氣虛, 氣血兩虛", the oriental term which indicates a condition of chronic disease or immunodeficiency. According to the oriental medicine principle, oriental medicine was taken such as Bojungyggi-tang(補中益氣湯), Palmul-tang(八物湯) and the patient had taken a turn for the better. After I month, MRSA was turned into Escherichia coli.

• The Journal of Internal Korean Medicine
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• v.38 no.6
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• pp.1085-1095
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• 2017

Objectives: The purpose of this study was to investigate the efficacy of Lijin-tang-gamibang on refractory gastroesophageal reflux disease (GERD). Methods: This before-and-after study compared the first medical examination and examination at the end of medical treatment. Twelve refractory GERD patients who visited the Department of Digestive Diseases of Kyung Hee University Korean Medicine Hospital from August 14th, 2017 to October 14th, 2017, were treated with Lijin-tang-gamibang for four consecutive weeks. The clinical characteristics of refractory GERD and the efficacy of herbal medical treatment was assessed by questionnaires, the Nepean Dyspepsia Index-Korean version (NDI-K), the Korean Gastrointestinal Symptom Rating Scale (KGSRS), the Numerical Rating Scale (NRS), the Korean version of the Perceived Stress Scale (KPSS-10), the Qi Stagnation Questionnaire (QSQ), the Spleen Qi Deficiency Questionnaire (SQDQ), and the Patient Global Impression of Change (PGIC). Prolonged effects were reported upon the follow-up telephone survey two weeks after treatment. Results: After treatment with the herbal medicine Lijin-tang-gamibang, the clinical characteristics of 12 refractory GERD patients were improved, especially in terms of the most common symptoms of acid regurgitation and heartburn. Each symptom score of NDI-K, KGSRS, NRS, SQDQ, and PGIC showed significant advances. Prolonged effects were reported in NDI-K, NRS and PGIC questionnaires two weeks after treatment. Conclusions: These results suggest that Lijin-tang-gamibang is an effective treatment for refractory GERD.

• Journal of Oriental Neuropsychiatry
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• v.21 no.4
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• pp.137-149
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• 2010

Objectives : The aim of this study was to describe the clinical aspects in dementia outpatients who visited oriental neuropsychiatry clinic and to analyze the efficacy of herbal medicine. Methods: We analysed medical records of dementia outpatients who visited oriental neuropsychiatry clinic of K medical center from August. 2000 to July, 2010 and matched our criteria. Results: Ninety-two subjects were selected for analysis and consisted of 77.3% dementia of Alzheimer type. 13.0% vascular dementia. and 9.8% mixed type of dementia. Herbal medicine prescribed mainly were Jowjseungchung-tang(Tiaowejshengqing-tang). Kunneo-tang(Jjannao-tang) and Chenwangbosim-dan(Tianwangbuxin-dan) for dementia of Alzheimer type, and Sunghyangjungki-san(Xjngxjangzhengqi-san) and Upung-dan (Yufeng-dan) for vascular dementia. Scores of K-DRS were not changed for some subs cales and decreased but less than natural decline of Alzheimer disease. Score on the Memory subscale in group of Kunneo-tang(Jjannao-tang) increased significantly. Conclusions : These results suggest that the herbal medicine may be effective for dementia. More prospective studies are needed to assess the efficacy and prognosis of herbal medicine for dementia. Clinical guideline is needed for systematic data accumulation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.1055-1059
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• 2002

Liuweidihuang-tang has been traditionally used for the treatment of delayed mental and physical development in children, complications of diabetes. and glomerulonephritis. In the present study, the effect of Liuweidihuang-tang on cell proliferation in the dentate gyrus of alcohol-intoxicated Sprague-Dawley rats was investigated via 5-bromo-2' -deoxyuridine (BrdU) immunohistochemistry. Alcohol administration was shown to decrease the number of BrdU-positive cells in the dentate gyrus, while Liuweidihuang-tang treatment increased new cell formation in the dentate gyrus under normal conditions and alcohol intoxication. It was thus demonstrated that aqueous extract of Liuweidihuang-tang exerts a protective effect against alcohol-induced decrease in new cell formation.