• Journal of Genetic Medicine
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• 제10권2호
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• pp.81-87
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• 2013

Pseudohypoaldosteronism (PHA), a rare syndrome of systemic or renal mineralocorticoid resistance, is clinically characterized by hyperkalemia, metabolic acidosis, and elevated plasma aldosterone levels with either renal salt wasting or hypertension. PHA is a heterogeneous disorder both clinically and genetically and can be divided into three subgroups; PHA type 1 (PHA1), type 2 (PHA2) and type 3 (PHA3). PHA1 and PHA2 are genetic disorders, and PHA3 is a secondary disease of transient mineralocorticoid resistance mostly associated with urinary tract infections and obstructive uropathies. PHA1 includes two different forms with different severity of the disease and phenotype: a systemic type of disease with autosomal recessive inheritance (caused by mutations of the amiloride-sensitive epithelial sodium channel, ENaC) and a renal form with autosomal dominant inheritance (caused by mutations of the mineralocorticoid receptor, MR). In the kidneys, the distal nephron takes charge of the fine regulation of water absorption and ion handling under the control of aldosterone. Two major intracellular actors necessary for the action of aldosterone are the MR and the ENaC. Impairment of the intracellular aldosterone signal transduction pathway results in resistance to the action of mineralocorticoids, which leads to PHA. Herein, ion handling the distal nephron and the clinico-genetic findings of PHA are reviewed with special emphasis on PHA type 1.

• Journal of Gastric Cancer
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• 제19권4호
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• pp.473-483
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• 2019

Surgical therapy for adenocarcinoma of the esophagogastric junction II requires distal esophagectomy, in which a transhiatal management of the lower esophagus is critical. The 'dorsal track control' (DTC) maneuver presented here facilitates the atraumatic handling of the distal esophagus, in preparation for a circular-stapled esophagojejunostomy. It is based on a ventral semicircular incision in the distal esophagus, with an intact dorsal wall for traction control of the esophagus. The maneuver facilitates the proper placement of the purse-string suture, up to its tying (around the anvil), thus minimizing the manipulation of the remaining esophagus. Furthermore, the dorsally-exposed inner wall surface of the ventrally-opened esophagus serves as a guiding chute that eases anvil insertion into the esophageal lumen. We performed this novel technique in 21 cases, enabling a safe anastomosis up to 10 cm proximal to the Z-line. No anastomotic insufficiency was observed. The DTC technique improves high transhiatal esophagojejunostomy.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 동계학술발표대회 논문집
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• pp.487-492
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• 2008

The cooling of data centers has emerged as a significant challenge as the density of IT server increases. Server installations, along with the shrinking physical size of servers and storage systems, has resulted in high power density and high heat density. The introduction of high density enclosures into a data center creates the potential for "hot spots" within the room that the cooling system may not be able to address, since traditional designs assume relatively uniform cooling patterns within a data center. The cooling system for data center consists of a CRAC or CRAH unit and the associated air distribution system. It is the configuration of the distribution system that primarily distinguishes the different types of data center cooling systems, this is the main subject of this paper.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.670-674
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• 2005

$D^*$ criterion is defined as a reference of the handling quality and ride comfortableness for lateral-directional automobile motion. However it is generally difficult to obtain the satisfied handling quality and ride comfortableness based on $D^*$ criterion by conventional two wheel steering system. In this study, a design method of model matching control system is proposed to obtain the satisfied $D^*$ response of 4 Wheel Steering.

• Korean Journal of Chemical Engineering
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• 제36권3호
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• pp.356-367
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• 2019

This work presents an advanced and systematic approach to analytically design the optimal parameters of a two parameter second-order internal model control (IMC) filter that satisfies operational constraints on the output process, the manipulated variable as well as rate of change of the manipulated variable, for a first-order plus dead time (FOPDT) process. The IMC parameters are designed to minimize a control objective function composed of the weighted sum of the error between the process variable and the set point, and the rate of change of the manipulated variable, and to satisfy the desired constraints. The feasible region of the constrained IMC control parameters was graphically analyzed, as the process parameters and the constraints varied. The resulting constrained IMC control parameters were also used to find the corresponding industrial proportional-integral controller parameters of a Smith predictor structure.

• 한국가스학회:학술대회논문집
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• 한국가스학회 1997년도 추계학술발표회 논문집
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• pp.33-38
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• 1997

Demand of the clean and convenient natural gas has continuously increased with recognizing of the environment problem since liquefied natural gas was introduced in Korea. Clean fuel natural gas was supplied to each city through high tensile strength pipeline connected by welding. Grades of pipeline were divided into the high and middle pressure according to supply pressure. Pipeline was welded mainly SMA welding process due to its easy handling, the other welding process was adopted according to the constructing condition. We were examined on the microstructure variation and mechanical properties of weld metal for high pressure pipeline, API 5L X-42.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2006년도 하계학술발표대회 논문집
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• pp.807-813
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• 2006

The objective of this study is to develop a rule-based fault detection algorithm and an experimental verification using an artificial air handling unit. To develop an analytical algorithm which precisely detects a tendency of faulty component, energy equations at each control volume of AHU were applied. An experimental verification was conducted on the HVAC simulator. The rule based FDD algorithm isolated a faulted sensor from HVAC components in summer and winter conditions.

• 한국보육지원학회지
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• 제8권4호
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• pp.185-206
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• 2012

본 연구의 목적은 어린이집 주임교사가 지각한 갈등관리 유형과 조직효과성을 알아보고, 어린이집 주임교사의 갈등관리 유형과 조직효과성과의 관계를 규명하는 것이다. 이를 위해 부산 및 경남지역에 소재한 어린이집 164곳에 근무하는 주임교사 194명을 대상으로 설문조사를 실시하였다. 연구결과, 주임교사들은 원장에 대해서는 배려적 유형을, 동료교사에 대해서는 통합적 유형을 가장 많이 사용했으며, 지배적 유형과 회피적 유형을 가장 적게 사용하는 것으로 나타났다. 주임교사가 지각하는 어린이집 조직효과성의 수준은 보통 이상이었으며, 주임교사의 연령, 학력, 경력, 시설유형 등 배경변인에 따라 갈등관리 유형 및 조직 효과성에 부분적인 차이가 있는 것으로 나타났다. 마지막으로 어린이집의 조직효과성은 주임교사의 갈등관리 유형 중 통합형과 지배형, 타협형과 정적인 상관관계가 있었으며 회피형과는 부적인 상관관계가 있는 것으로 나타났다. 어린이집의 조직효과성에 가장 영향을 미치는 주임교사의 갈등관리 유형은 원장에 대해서는 회피형이었으며, 동료교사에 대해서는 통합형인 것으로 나타났다.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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• pp.1459-1462
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• 2008

In this paper we describe solutions to address critical challenges in direct fabrication of amorphous silicon thin film transistor (TFTs) arrays for active matrix flexible displays. For all flexible substrates a manufacturable handling protocol in automated display-scale equipment is required. For metal foil substrates the principal challenges are planarization and electrical isolation, and management of stress (CTE mismatch) during TFT fabrication. For plastic substrates the principal challenge is dimensional instability management.

• 한국항해항만학회지
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• 제29권1호
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• pp.1-7
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• 2005

항만을 출입항하는 선박의 통항 안전을 확보하기 위해서는 방파제와 같은 항만 시설물의 설계 또는 배치시에는 우선적으로 선박의 조종 성능을 감안하여 교통 흐름이 원활하도록 적정한 항로를 지정하여야 한다. 이 연구에서는 부산항 및 감천항 입항을 위해 방파제 인접 항로에서 일정 침로로 접근하는 컨테이너 선박이 외력인 바람, 조류, 파랑에 의해 선체에 발생하는 횡압류 및 회두 현상을 정량적으로 분석하여, 선속에 따라 외력을 상쇄하기 위해 취해야 할 대응타각을 산출한다. 또한 향후 방파제 설계 및 배치시 고려해야 될 외력하의 선박의 조종 성능요소를 제안함과 동시에 방파제의 설계와 항로 배치와의 관계에 대하여 고찰한다.