• 제목/요약/키워드: On Resistance

검색결과 21,498건 처리시간 0.05초

돼지유래 Salmonella Schwarzengrund의 약제내성 유전자에 관한 연구 (Investigation on antimicrobial resistance genes of Salmonella Schwarzengrund isolated from pigs)

  • 이우원;김상현;이승미;이강록;이기흔;김용환
    • 한국동물위생학회지
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    • 제35권1호
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    • pp.1-8
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    • 2012
  • To detect the virulence genes (invA and spvC) and antimicrobial resistance genes, polymerase chain reaction (PCR) was carried out using total 67 strains of S. Schwarzengrund isolated from pigs. As results, invA was detected from all 67 strains of S. Schwarzengrund, however, spvC was not at all. All 12 strains with ampicillin resistance, 15 strains with chloramphenicol resistance, 9 strains with kanamycin resistance, 1 strain with sulfamethoxazole/trimethoprim resistance, and 66 (98.5%) of 67 strains with tetracycline resistance carried TEM (${\beta}$-lactamase $bla_{TEM}$), cmlA (nonenzymatic chloramphenicol resistance), aphA1-Iab (aminoglycoside phosphotransferase), sulII (dihydropteroate synthase), and tetA (class A tetracycline resistance), respectively. All 63 strains with streptomycin resistance carried 3 aminoglycoside resistance genes, including aadA (aminoglycoside adenyltransferase), strA, and strB (streptomycin phosphotransferase). With respect to prevalence of antibiotic resistance genes occurred in S. Schwarzengrund, genes for strB (46.0%); strA and strB (30.2%); aadA, strA, and strB (9.5%); strA (7.9%); aadA and strB (3.2%); and aadA (3.2%) were detected by PCR.

서해안 수산생물에서 분리한 대장균(Escherichia coli)의 항생제 내성 및 다제 내성 양상 비교 (Comparison of Antimicrobial Resistance and Multi-Drug Resistance Patterns of Escherichia coli Isolated from Aquatic Organisms Off the West Coast of South Korea)

  • 정연겸;박보미;김민주;박진일;정연중;오은경
    • 한국수산과학회지
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    • 제54권4호
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    • pp.388-396
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    • 2021
  • Antimicrobial resistance patterns of Escherichia coli were investigated. Strains were isolated from 310 shellfish, 36 crustaceans, and 12 fish collected off the West Coast of Korea from April 2019 to October 2020. Two hundred and ninety-five E. coli strains were isolated from shellfish, 100 from crustaceans, and 54 from fish. Strains isolated from shellfish showed the highest resistance to ampicillin (27.5%), whereas those from crustaceans were resistant to sulfisoxazole (30.0%) and those from fish were resistant to ampicillin (59.3%) and sulfisoxazole (59.3%). Ceftazidime resistance was observed in strains isolated from short neck and hard clams, whereas gentamicin resistance was observed in strains from fish. Multi-drug resistance was observed in 56 strains (48.7%) isolated from shellfish, 11 (28.2%) from crustaceans and 27 (73.0%) from fish. Depending on the source of isolation, the strains showed specific antimicrobial resistance tendency. Strains isolated from shellfish showed 12 different multi-drug resistance patterns, whereas those from crustaceans showed high resistance (59%) to a single antimicrobial agent and those from fish showed a broad trend of multi-drug resistance to more than eight antimicrobials.

마케팅관리자들이 어떻게 혁신에 대한 소비자저항을 극복할 수 있는가? - 혁신에 대한 소비자의 개인적 사회적 저항의 근원 탐색 - (How Can Marketers Overcome Consumer Resistance to Innovations? - The Investigation of Psychological and Social Origins of Consumer Resistance to Innovations -)

  • Bagozzi, Richard P.;Lee, Kyu-Hyun
    • 마케팅과학연구
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    • 제15권3호
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    • pp.211-231
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    • 2005
  • 마케팅관리자들이 글로벌 시장에 혁신을 성공적으로 진출시키기 위해서는 개인적 저항과 집단 저항에 대하여 이해하는 것이 중요하다. 우리가 제한하기로는 소비자들은 개인으로서, 집단의 한 구성원으로서 혁신에 저항하며, 의사결정의 다른 단계에 다른 방법으로 저항한다. 개인적인 저항은 초기저항(initial resistance)의 형태에서 시작하여 급박한 저항(emergent resistance)으로 발전하고 최종적으로는 늦은 저항(belated resistance)으로 발전한다. 또한, 개인의 도덕적 기준이 혁신수용 의사결정에 영향을 미칠 수 있다. 때때로 개인적 저항은 집단저항에 의해서 수반되거나 집단저항으로 진화한다. 우리는 혁신에 대한 소비자저항을 개인에 대하여, 개인이 속한 집단에 대하여, 다른 개인과 집단에 대하여 작용하는 사회정체감의 결과로서 생각하는 체계를 제시한다. 어떤 집단 구성원인 소비자들은 사회비교과정을 통하여 자아존중감을 증가시킨다. 소비자들이 어떤 집단에 대하여 강한 정체감을 가지고 결속하면 할수록, 내부집단 결속력과 외부집단 배타성이 더 많이 나타난다. 외부 집단 배타성은 집단 구성원들에게 외부 집단과 관련된 제품과 서비스에 대하여 강한 저항을 나타낸다. 개인적인 저항과 집단 저항은 마케팅관리자들을 위협하고 성과를 침해한다. 혁신에 대한 저항의 존재를 고려하고, 극복하려는 전략을 추구함으로써 마케팅관리자들은 이러한 위협을 새로운 기회로 전환시킬 수 있다. 소비자저항에 대한 이해는 혁신의 소비자수용에 대한 연구를 보완하고, 소비자행동의 보편적인 모형을 개발하는 데 도움이 될 수 있다.

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검증용 정재하시험을 이용한 타입강관말뚝의 저항계수 보정 (Local Resistance Factor Update of Driven Steel Pipe Piles Using Proof Pile Load Test Results)

  • 박재현;김동욱;정충기;김성렬
    • 대한토목학회논문집
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    • 제31권6C호
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    • pp.259-266
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    • 2011
  • 기초구조물의 신뢰성 있는 저항계수 산정을 위해서는 충분한 양의 재하시험 결과에 근거한 저항의 분포특성 분석이 선행되어야 한다. 본 연구에서는 베이지안 이론에 근거하여 검증용 정재하시험 결과를 저항의 분포특성 분석에 반영할 수 있는 개선된 해석법을 제안하였고, 이를 통해 기 제안된 국내 타입강관말뚝의 저항계수를 갱신하였다. 측정 지지력이 확인된 정재하시험 결과를 이용하여 저항의 사전 분포특성을 산정하고, 검증용 정재하시험 결과를 우도정보로 고려하여 저항의 사후 분포특성을 평가하였다. 갱신된 저항의 사후 분포특성을 이용하여 일차신뢰도법에 의해 저항계수를 산정하였다. 총 5회의 검증용 재하시험 결과를 반영할 경우, 갱신된 저항계수는 목표신뢰도지수 2.33, 3.0에 대하여 각각 0.27-0.96, 0.19-0.68의 범위를 나타내었다. 본 연구에서 제시된 해석법을 통해 양질의 측정지지력 데이터가 부족하여 신뢰성 있는 저항계수를 산정하기 어려운 경우 현장 검증시험 결과를 반영한 저항계수의 보정이 가능함을 확인하였다.

저항운동 프로그램이 제 2형 당뇨병 노인의 자가간호, 스트레스 및 당화혈색소에 미치는 효과 (The Effects of Resistance Exercise Program for Elders with Type 2 Diabetes on the Self Care, Stress and HbA1c)

  • 이선우;신성례
    • 성인간호학회지
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    • 제20권3호
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    • pp.431-442
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    • 2008
  • Purpose: The purpose of this study was to examine the effects of resistance exercise program for elders with type 2 Diabetes on the self care, stress and HbA1c. Methods: Thirty three elders with type 2 Diabetes(18 experimental and 15 control subjects) were selected conveniently among the aged who had been enrolled in a community senior center. The subjects in experimental group participated in a resistance exercise program for 8 weeks. Data were analyzed using the SPSS/Win 12.0. Results: The resistance exercise program showed a statistical difference in self care(t=-4.39, p=.000) and stress(t=2.22, p=.034). However, there was not a statistical difference in HbA1c (F=.556, p=.557), but experimental group had decreased continuously in HbA1c after the program. Conclusion: The resistance exercise program improved self care and reduced the stress in the elders with type 2 Diabetes. Therefore, resistance exercise program can be applied as an effective nursing intervention to promote self care, decrease the stress and to prevent complication for the elders with type 2 Diabetes.

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Ro-Pax 선형의 천수역에서 조파저항성능 평가를 위한 수치적 연구 (A Numerical Study to Evaluate the Resistance Performance of a Ro-Pax Hull Form in Shallow Water)

  • 홍춘범;신수철;김정중;최순호
    • 대한조선학회논문집
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    • 제42권4호
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    • pp.315-321
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    • 2005
  • The effect of water depth on the wave making resistance performance is great where Froude number based on the water depth is close to one. The increase of wave making resistance due to the shallow water effect is evaluated by a numerical analysis in the present study. Three-dimensional Navier-Stokes and continuity equations are employed for the present study and the equations are discretized by finite difference method. The interface between water and air is determined by the level set method. In order to validate the numerical method, the change of resistance performance for Wigley hull according to the water depth is evaluated and the computed resistance coefficient is compared with measured one. The present numerical method is applied for the simulation of wave phenomena around a Ro-Pax hull form and the computed results are discussed in the resistance performance point of view.

중방식도료의 내식성에 관한 전기화학적 평가 (An Electrochemical Evaluation on the Corrosion Resistance of Heavy Anticorrosive Paint)

  • 성호진;김진경;이명훈;김기준;문경만
    • Journal of Advanced Marine Engineering and Technology
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    • 제29권5호
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    • pp.519-525
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    • 2005
  • An electrochemical evaluation on the corrosion resistance for heavy anticorrosive paint(DFT:25um) was carried out for 5 kinds of heavy anticorrosive paints such as high solid epoxy(HE), solvent free epoxy(SE). tar epoxy(TE), phenol epoxy(PE). and ceramic epoxy(CE). Corrosion current densities obtained by Tafel extrapolation method from anodic and cathodic polarization curves didn't correspond with the values obtained by AC impedance measurement, however, the values of polarization resistance obtained from the cyclic voltammogram showed a good tendency corresponding well with the values of AC impedance measurement. Futhermore there was a good correlation against the corrosion resistance evaluation between passivity current density of the anodic polarization curve and diffusion limiting current density of the cathodic polarization curve. And corrosion resistance increased with corrosion potential shifting to noble direction. From the results discussed above. HE and CE had a relatively good corrosion resistance than other heavy anticorrosive paints.

정규화법을 이용한 원전배관 용접부의 동하중 파괴저항시험 (Dynamic Fracture Testing of Welding part of Nuclear Piping by Using Normalization Method)

  • 허용;조성근;박재실;석창성
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 추계학술대회
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    • pp.262-267
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    • 2004
  • The unloading compliance method is the most commonly used method to evaluate the fracture resistance characteristics of a material. In dynamic loading condition, the direct current potential drop(DCPD) method has been used because the unloading compliance method can not be applied due to the discontinuity of loading. However, even in the dynamic test using DCPD method, there is a problem that the voltage drops sharply on the initiation of crack. For the reason metioned above, the normalization method was suggested on ASTM E 1820 which is revised recently, as a new method to evaluate the dynamic fracture resistance characteristic. The nomalization method can be used to obtain a fracture resistance curve directly from a load-load line displacement. In this study, we obtained two fracture resistance curves from static test of welding part of nuclear piping both by unloading compliance and nomalization method. The two curves were almost same each other, so the adaptability of the nomalization method has been proved. We conducted a dynamic fracture resistance test for the same material. The fracture resistance curve from the dynamic test was obtained by normalization method and compared to that of the static test result.

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올레인산 및 프로필렌글리콜이 피부의 전기적 성질에 미치는 영향 (The Effect of Oleic Acid and Propylene Glycol on the Electrical Properties of Skin)

  • 오승열
    • Journal of Pharmaceutical Investigation
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    • 제24권4호
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    • pp.281-287
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    • 1994
  • The effects of oleic acid, propylene glycol and 5% (w/w) oleic acid in propylene glycol on the electrical properties of hairless mouse skin were studied and the results were compared. The complex electrical impedance was measured as a function of frequency, and resistance and capacitance were determined from the Nyquist plot. Immediately after the treatment with oleic acid, resistance was 145% of the pretreatment value. However it decreased with time and, after 20 hours, it was about 25% of its pretreatment value. Capacitance increased; immediately after the treatment, it was about 125% of pretreatment value and it seemed to increase slowly with time. When the skin was treated with propylene glycol, resistance decreased about 5O% and capacitance increased about 65%. Similar results were observed when the skin was treated with 5% (w/w) oleic acid in propylene glycol, except that the magnitude of resistance drop was much larger. Oleic acid acted synergistically with propylene glycol. Together with the flux data in the literature, the results obtained in this work indicate that electrical resistance is closely related to the permeability of drug molecules through the skin. The results are discussed in terms of the mechanism of action of these penetration enhancers. Overall, this work provided further mechanistic insight into the role of SC lipids in skin resistance and capacitance.

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2205 2상 스테인리스강의 내식성에 미치는 텅스텐 치환의 영향 (Effect of Tungsten-Substitution on the Corrosion Resistance of 2205 Duplex Stainless Steel)

  • 김기엽;안용식;정병호
    • Journal of Advanced Marine Engineering and Technology
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    • 제27권6호
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    • pp.704-713
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    • 2003
  • The effect of partial substitution of tungsten for molybdenum on the microstructure and corrosion resistance in 22Cr-5Ni-3Mo duplex stainless steel(DSS) aging heat treated in a temperature range of 600~$1000^{\circ}C$ has been investigated. Electrochemical tests were carried out for the evaluation of corrosion resistance. Aging treatment had hardly influenced the general corrosion resistance. With the increase of aging time, the pitting corrosion resistance of the DSS had decreased, After aging for 2min at 700~$900^{\circ}C$, the pitting potential of the 3Mo steel decreased remarkably, while that of the W-substituted steel hardly changed. During aging. the intermetallic $\sigma$ and secondary austenite ($\gamma_2$) phases were precipitated. and the pitting corrosion and intergranular corrosion resistance were significantly decreased after aging at 700~$750^{\circ}C$ for 10 h, which could be caused by the $\gamma_2$ formation. The ${\gamma}$$_2$ phase could affect the depletion of molybdenum and chromium in the $\gamma_2/\alpha and \gamma_2/\sigma$ boundaries.