• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2375-2378
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• 2015

Background: The effects of diet on epidemiology of prostate cancer are inconclusive. Therefore a hospitalbased, case-control study was conducted in a rural population of Faisalabad, Pakistan, to examine the impact of dietary factors on risk of cancer development. Materials and Methods: This study was based on 102 confirmed cases of prostate cancer and 204 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals for odds ratios to evaluate the relationship between prostate cancer and diet. Results: Consumption of red meat and fat items significantly increased the prostate cancer risk having odds ratios and 95% confidence intervals of 3.41; 1.46-7.96 and 2.45; 1.17-5.15, respectively. On the other hand, more consumption of vegetables, fluid intake and fruit significantly decreased the prostate cancer risk (odd ratios and corresponding 95% confidence intervals of 0.21; 0.10-0.44, 0.10; 0.05- 0.19 and 0.09; 0.03- 0.23, respectively. Conclusions: The present study supports the hypothesis that frequent consumption of red meat and fat items may increase prostate cancer risk while more intake of fruit, vegetables and fluid intake may protect against prostate cancer in the relatively low risk group in rural Pakistan.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10237-10240
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• 2015

Background: Prostate cancer is the third most commonly diagnosed cancer among males in Pakistan but very little is known about risk factors among the Pakistani population. Therefore a hospital-based, case-control study was carried out in Faisalabad to identify potential risk factors. Materials and Methods: This study was based on 140 prostate cancer cases and 280 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals for odds ratios to assess the relationship between prostate cancer and different risk factors. Results: Family history of prostate cancer, age, smoking, obesity, consumption of red meat and frequent use of fat items significantly increased the prostate cancer risk (odds ratios and 95% confidence intervals of: 7.32; 1.79-29.8; 16.9, 5.60-50.8; 2.47, 1.17-5.18; 5.79, 2.66-12.6; 2.71, 1.07-6.91; and 3.39, 1.47-7.83, respectively. On the other hand, more consumption of fruit, fluid intake and better lifestyle (physical activity) significantly reduced the risk of developing prostate cancer with odd ratios and corresponding 95% confidence intervals of: 0.27, 0.11-0.61; 0.05, 0.02-0.12; and 0.28, 0.13-0.58. Conclusions: The results of the present study suggested that age, family history of prostate cancer, smoking, obesity, fluid intake, frequent use of fat items, consumption of fruits and better lifestyle might be associated with prostate cancer among Pakistani males.

• Journal of Preventive Medicine and Public Health
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• 제56권4호
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• pp.368-376
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• 2023

Objectives: Recent research indicates a potential association between workplace violence and an increased risk of cardiovascular disease (CVD) in the working-age population. However, the relevant evidence in the United States is sparse. Thus, this study was conducted to explore the possible relationship between workplace violence and CVD among United States workers. Methods: We utilized cross-sectional data from the 2015 National Health Interview Survey, which included a representative sample of 18 380 workers, to investigate the associations between workplace violence and the prevalence of CVD using logistic regression. Workplace violence was determined based on self-reported threats, bullying, or harassment at work over the past 12 months, supplemented with additional information regarding frequency. CVD included all forms of heart disease and stroke. Results: A total of 1334 workers reported experiences of workplace violence, and 1336 workers were diagnosed with CVD. After adjustment for covariates, participants who reported any instance of workplace violence had significantly higher odds of having CVD (odds ratio [OR], 1.76; 95% confidence interval [CI], 1.35 to 2.30) than those who reported no such violence. Furthermore, the highest odds of CVD (OR, 1.80; 95% CI, 1.23 to 2.63) were observed among those frequently exposed to workplace violence. Even occasional exposure to workplace violence was associated with 74% excess odds of CVD. Conclusions: Our study indicates an association between workplace violence and CVD in United States workers, exhibiting a dose-response pattern.

• 디지털융복합연구
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• 제14권12호
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• pp.13-25
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• 2016

본 연구는 2012년부터 2014년까지 국민연금 임의가입자의 계약자 및 계약특성이 해약 행동에 미치는 효과를 로지스틱 회귀모형을 사용하여 분석하였다. 첫째, 남성이 여성보다 탈퇴 오즈가 낮으며 신규가입자 집단에서는 더 큰 차이를 보인다. 둘째, 연령이 증가함에 따라 탈퇴 오즈는 증가하다가 감소하는 특징을 보인다. 셋째, 예상 수익비의 증가는 탈퇴 행동을 억제하는 것으로 나타났다. 넷째, 2013년 국민연금과 기초연금 간 연계 안 발표 결과 전년도에 비해 탈퇴 오즈가 증가하였고 신규가입자 집단에서는 그 크기가 더 크게 나타났다. 다섯째, 17개 광역시 도를 기준으로 광역시 단위에 거주하는, 도시지역 가입자의 탈퇴 오즈가 낮은 것으로 나타났다. 한편, 가입기간과 기준소득 월액과 같은 계약특성의 경우, 탈퇴 오즈에 미치는 영향은 유의미하지만 크기는 작게 나타났다. 본 연구는 향후 임의가입자 유형별 관리방안에 대한 아이디어를 제시하고 특히 예상 수익비의 변화가 해약률에 미치는 영향을 예측할 수 있음을 보였다.

• 한방비만학회지
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• 제14권2호
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• pp.63-71
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• 2014

목적: 본 연구는 사상체질과 이상지질혈증의 상관관계 및 사상체질이 이상지질혈증의 위험요인이 될 수 있는가를 탐색하는 데 목적이 있다. 방법: 본 연구는 의무기록을 바탕으로 한 후향적 단면조사연구로, 2007년 5월부터 2010년 6월까지 서울 소재 경희의료원 건강증진센터에 내원한 건강검진 수진자 17,069명의 의무기록을 조사하여 사상체질진단검사 결과 및 생화학검사 결과 등이 확인된 15,250명을 대상으로 사상체질과 이상지질혈증 간의 상관관계를 조사하였다. 결과: 총 콜레스테롤과 중성지방은 체질량지수(body mass index, BMI)를 보정한 상태에서 태음인, 소양인, 소음인 등의 순서로 높았고, 고밀도 콜레스테롤은 소음인, 소양인, 태음인 순서로 높았다. 연령, 성별, BMI 등을 보정한 상태에서 '높은 중성지방'에 대한 odds ratio는 소음인에 비해 소양인이 1.716 (1.411~2.087), 태음인이 2.021 (1.650~2.475)이었으며, '높은 저밀도콜레스테롤'에 대한 odds ratio는 소음인에 비해 소양인이 1.229 (1.006~1.501)였고, '낮은 고밀도 콜레스테롤'에 대한 odds ratio는 소음인에 비해 소양인이 1.195 (1.033~1.381), 태음인이 1.414 (1.212~1.649)였다. 결론: 사상체질에 따라 일부 이상지혈증의 분포 및 odds ratio에 유의한 차이가 있었고, 이에 따라 사상체질이 이상지질혈증의 위험요인이 될 수 있는 가능성을 찾을 수 있었다.

• 보건의료산업학회지
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• 제8권3호
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• pp.137-145
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• 2014

The objective of this study was to analyze the risk of preterm birth (PTB) and low birth weight (LBW) in extramarital birth by analyzing 2008-2012 birth certificated data (2,328,719 births) from Korea Statistics. Odds ratio and 95% confidence intervals (95% CI) were calculated from logistic regression analyses to describe the associations between PTB & LBW and extramarital birth adjusted for maternal age, maternal occupation & education, infantile sex, birth order and number of child birth (singleton & multiple birth). The rate of extramarital birth was 1.8 percent and 2.1 percent in 2010-11. The incidence of LBW was 8.1 percent in extramarital birth and 5.0 percent in marital birth. The incidence of PTB in extramarital birth were 8.2 percent and 5.8 percent in marital birth. Compared with marital birth, the odds ratio (OR) for PTB were 1.48 (95% CI: 1.43-1.54) for extramarital birth. Risk of LBW was higher in extramarital birth (OR: 1.70, 95% CI: 1.64-1.76) than that of marital birth. Among mothers younger than 20 years, the odds ratio of PTB among extramarital birth, relative to married birth was 1.69 (1.49-1.91). Among unmarried mothers, those at a higher risk of LBW was aged 20-29 years (1.69: 1.59-1.79). Maternal unmarried status was associated with increased risk of PTB and LBW.

• 한국산학기술학회논문지
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• 제15권7호
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• pp.4353-4360
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• 2014

이 연구는 우리나라 노인의 구강건강 개선을 위하여 현재 저작 불편 호소와 치과 보철 필요와의 관련성을 평가하고자 하였다. 연구대상자는 제5기 1차년도 국민건강영양조사에 참여한 65세 이상 노인 1,177명을 대상으로 조사를 실시하였다. 구강검사를 통하여 상실치아와 필요 보철 상태를 파악하였으며, 구조화된 설문도구를 이용하여 사회경제요인, 구강건강 관심도, 저작능력과 발음문제를 조사하였다. 수합된 자료는 SPSS 19.0 프로그램을 사용하여 분석하였다. 우리나라 노인의 42.9%는 저작 불편을 호소하였으며, 로지스틱 회귀분석을 통하여 혼란변수를 보정한 결과 고정 보철 필요 위험비는 1.22, 부분의치 필요 위험비는 2.47, 총의치 필요 위험비는 2.06이었다. 치과보철 필요는 저작 불편 호소와 관련이 있었다. 따라서 노인을 위한 치과 보철 정책과 구강건강증진의 뒷받침이 가장 필요하다.

• Journal of Preventive Medicine and Public Health
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• 제32권4호
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• pp.427-434
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• 1999

Objectives: This study was conducted to determine, by reviewing the literature, whether treatment of Helicobacter pylori infection in patients with non-ulcer dyspepsia affects symptoms. Methods: We retrieved the literature using MEDLINE search, with nonulcer dyspepsia and Hericobacter pylori and treatment as key words, which were reported from 1984 to 1998, and manual literature search. The criteria for inclusion was as follows; 1) The paper should have confirmed nonulcer dyspepsia as case definition. 2) The paper should have peformed a randomized, blind trial. 3) Confirmation of Helicobacter pylori eradication should be done 4 weeks after treatment. 4) studies with no information on measurement of symptoms after treatment were not accepted. The percentage of patients with symptom improvement after eradication therapy for Helicobacter pylori infection was calculated. Cumulative odds ratio was compared by fixed effect model and random effect model as sensitivity and funnel plot was used to evaluate publication bias. Results: The overall effect size of symptom improvement was calculated by cumulative odds ratio. Cumulative odds ratio of random effect model was 4.16(95% CI: 1.55-11.19). Before integrating each effect sizes into common effect size, the homogeneity test was conducted and random effect model was selected(Cochran's Q=41.08 (d.f=10, p<0.001)). The heterogeneity across studies was evaluated and the different methodological aspects of studies led to differences between study results Conclusions: The results suggest that the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia results more symptom improvement. In studios that shows the opposite results there are methodological aspects explaining the heterogeneity.

• 한국도로학회논문집
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• 제13권4호
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• pp.199-209
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• 2011

교통사고발생시 사고 심각도에 영향을 미치는 요인과 그 관계를 이해하는 것은 기하구조나 환경 측면에서 교통사고 발생을 예방하고 운전자와 사고 차량의 특성을 이해하는데 도움을 준다. 본 연구에서는 계층 이항 로지스틱모형에 의해 고속도로 교통사고 심각도에 영향을 미치는 요인을 파악하고 영향변수 간 차이를 나타내는 비교위험도(odds ratio)를 도출하였다. 사고 심각도는 인명피해와 차량피해로 구분하여 사망사고모형과 차량완파사고모형을 구축하였다, 종속변수는 사망자 발생과 완파차량 발생 여부이며, 각각 사고-탑승자, 사고-차량의 2수준 계층구조를 적용하였다. 추정 결과 설명변수의 고정효과는 두 모형이 유사한 결과를 보이나 종속변수의 속성에 따라 차별화된 결과를 나타내기도 하였다. 본선과 진출입부에서의 사고가 가장 위험하며, 중앙선 침범과 통행위반, 과속 사고의 상해나 차량 파손 위험도가 높고, 충돌사고와 추돌사고, 화재 사고의 피해가 크다. 사고 심각도는 노면 상태나 시야 조건 등 외부환경에 영향을 받으나 기하구조 조건은 관련이 없다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9077-9083
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• 2014

Background: This study aimed to summarize the potential diagnostic value of serum DKK1 levels in cancer detection. Materials and Methods: Serum DKK1 was measured using enzyme-linked immunosorbent assay in a case-control study. Then we performed a meta-analysis and the pooled sensitivity, specificity, diagnostic odds ratio, and summary receiver operating characteristic (sROC) curves were used to evaluate the overall test performance. Results: Serum DKK1 levels were found to be significantly upregulated in gastric cancer as compared to controls. ROC curve analysis revealed an AUC of 0.636, indicating the test has the potential to diagnose cancer with poor accuracy. The summary estimates of the pooled sensitivity, specificity and diagnostic odds ratio in meta-analysis were 0.55 with a 95% confidence interval (CI) (0.53-0.57), 0.86 (95%CI, 0.84-0.88) and 12.25 (95%CI, 5.31-28.28), respectively. The area under the sROC was 0.85. Subgroup analysis revealed that the diagnostic accuracy of serum DKK1 in lung cancer (sensitivity: 0.69 with 95%CI, 0.66-0.74; specificity: 0.95 with 95%CI, 0.92-0.97; diagnostic odds ratio: 44.93 with 95%CI, 26.19-77.08) was significantly higher than for any other cancer. Conclusions: Serum DKK1 might be useful as a noninvasive method for confirmation of cancer diagnosis, particularly in the case of lung cancer.