• Asian-Australasian Journal of Animal Sciences
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• 제17권11호
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• pp.1608-1614
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• 2004

This study was performed to evaluate the accuracy, validation and applicability of UV spectrophotometer (UV), Ion Chromatography (IC), and Detector tube (DT) methods for measuring ammonia (NH3) concentration in a swine confinement house and swine slurry storage tank. The mean values of $NH_{3}$ emitted from the house and slurry were 5.333 ppm and 42.192 ppm for the IC method; 4.13 ppm and 36.29 ppm for the Detector tube; and 5.417 ppm and 34.193 ppm for the UV method. The accuracy and the correlation of an ammonia level analyzed by the IC method compared to the UV method were 98% and 0.998($R^{2}$) in the swine confinement house and 94% and 0.997($R^{2}$) in the swine slurry storage tank. On the other hand, those of ammonia level measured by the Detector tube compared to the UV method were 77% and 0.957($R^{2}$) in the swine confinement house and 82% and 0.941($R^{2}$) in the swine slurry storage tank. This indicated that the accuracy and the correlation of the IC method compared to the UV method were higher than those of the Detector tube method compared to the UV method. Therefore, it was concluded that the IC method was more accurate in measuring ammonia concentration in a swine house and a swine slurry storage tank. The Detector tube method should not be applied to the swine slurry storage tank in which ammonia concentration is generally higher than 30 ppm because low accuracy is caused by a gross space between scales inscribed in the Detector tube.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.8923-8929
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• 2014

Background: Increasing evidence suggests that stromal monocarboxylate transporter 4 (MCT4) and carbonic anhydrase IX (CA IX) may play key roles in tumor development. However, their clinical value remains largely unexplored in gastric cancer (GC). The present study aimed to determine clinicopathological significance and prognostic values of stromal MCT4 and CA IX in GC. Materials and Methods: Specimens from 143 GC patients were immunohistochemically stained using polyclonal anti-MCT4 and anti-CA IX antibodies. Expression was correlated with patient clinicopathologic characteristics and survival data. Results: High stromal MCT4 expression was detected in 72 of 143 (50.3%) GCs and high CA IX in 74 (51.7%). Both high stromal MCT4 and CA IX were correlated with advanced TNM stage (p=0.000; p=0.000). High CA IX expression was positively related to depth of invasion (p=0.022) and positive lymph nodes (p=0.002) as well. Survival analysis indicated high expression of stromal MCT4 to be an independent factor in predicting poor overall survival (OS) (HR and 95%CI=1.962, 1.032-3.729, p=0.040) and disease free survival (DFS) (HR and 95%CI=2.081, 1.158-3.741, p=0.014) of GC patients. However, high CA IX expression exhibited no significant predictive value. Conclusions: These findings suggest that high expression of stromal MCT4 and CA IX proteins is significantly correlated with GC progression. High stromal MCT4 heralds worse outcome of GC patient, suggesting a novel candidate prognostic marker and therapeutic target.

• 센서학회지
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• 제26권5호
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• pp.314-323
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• 2017

Indicators to quantitatively evaluate the body function may help to optimize the effectiveness of rehabilitation therapy for stroke patients. In this study, we analyzed the body composition in the paretic and nonparetic regions of stroke patients with hemiplegia caused by cerebral hemorrhage (7 cases) and cerebral infarction (13 cases) using multifrequency bioelectrical impedance. Specifically, we considered fat mass (FM), fat-free mass (FFM), FFMI index (FFMI), FM/FFM relation, body cell mass (BCM), basal metabolic rate (BMR), and BMR/FFM relation to evaluate the bodily function in the paretic and nonparetic regions. These values showed considerable differences according to grades determined by the stroke causes and the paralysis status. In the paretic regions, the FFM, FFMI, BCM, and BMR were low and the FM was high. In contrast, the nonparetic regions showed a high FFM and low FM. Furthermore, the paretic and nonparetic regions of all patients suitably fit a linear relation (slope: 22.17 kcal/day/kg) between BMR and FFM. Therefore, bio-electrical impedance measurements can be very useful to quantitatively assess paretic and nonparetic regions in hemiplegic stroke patients.

• 한국전문물리치료학회지
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• 제15권1호
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• pp.46-53
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• 2008

The aim of the present study was to determine the effect of proprioceptive neuromuscular facilitation (PNF) leg patterns on the muscle activation of neck flexors. Twenty healthy subjects participated in this study. Each subject performed bilateral asymmetrical PNF leg patterns against manual resistance under four conditions: through the full range of motion toward the right side, left side, and the end range in the right side, left side. Electromyographic (EMG) data was collected from the sternocleidomastoid (SCM) muscles as neck flexors. The root mean square (RMS) value of the SCM was measured and normalized from maximal EMG activity of the SCM. The data were analyzed using the paired t-test and repeated analysis of variance (ANOV A) was used to compare the statistical significance. The results of this study are summarized as follows: Firstly, the RMS values of SCM were significantly higher in all four PNF leg patterns than in the resting condition (p<.05). Secondly, there was no significant difference in muscle activation according to the direction of PNF leg patterns (p>.05). Thirdly, there was no significant difference in muscle activation according to the point of range of the motion of leg patterns (p>.05). It is suggested that PNF bilateral asymmetrical leg patterns have a considerable effect on muscle activation of the SCM, regardless of the range of motion and direction of PNF bilateral asymmetrical leg patterns.

• 대한안전경영과학회지
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• 제12권4호
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• pp.67-72
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• 2010

This study was done to provide basic data on the safety of professionals in medical imaging system by measuring the electromagnetic waves generated in the medical imaging system being used in medical organization. The studied medical imaging systems were general X-ray system, computed tomography(CT), ultrasonographic(USG) system, magnetic resonance imaging(MRI), PET-CT and fluoroscopic(R/F) system, and through these devices, electric field and magnetic field were measured and analyzed. As a result of the analysis, the measured values classified by the medical organizations were not much significant, but in the measurement by the medical imaging systems, there were high hazard elements in the sequential order of electric field PET-CT($17.7{\pm}22.9$)v/m, CT($10.3{\pm}8.7$)v/m, general X-ray system($8.8{\pm}8.8$)v/m, magnetic field general X-ray system($5.06{\pm}8.26$)mG, CT($2.71{\pm}4.53$)mG and PET-CT($0.74{\pm}0.34$)mG, the systems that adopted X-ray as main ray source, and the more aged the medical imaging systems, the greater the effects of electro-magnetic waves($10.6{\pm}15.93v/m$ for 5 years or more, $6.14{\pm}5.60v/m$ for 5 years or less). The effects of electromagnetic waves on medical imaging systems or facilities were not much when the notification of ministry of knowledge economy is considered, but in the overall perspective considering all the equipments and facility of the medical organization, such effects were significant. It is determined that sustainable safety managements of electric field and magnetic field must be done during process from medical imaging system installation to maintenance to rule out such factors.

• 대한안전경영과학회지
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• 제11권3호
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• pp.79-85
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• 2009

In this study, the effects of psychosocial stress (box color and precision demand) on muscle activity were evaluated in laboratory setting. Eight subjects performed sagittally symmetric lifting tasks. Box color (yellow, black), precision demand (yes, no), and box weight (5%MVC, 10%MVC, 15 %MVC) were varied and surface EMG signals from seven muscles(medial deltoid right, biceps brachii right, lateral triceps right, latissimus dorsi right, erector spinae right, external oblique right, internal oblique right) were recorded. EMG signals were band-pass filtered($10{\sim}400\;Hz$), rectified, RMS smoothed and normalized (NEMG). Analysis of variance tests were conducted on the total NEMG (TNEMG: the sum of the seven muscles' NEMGs) and on the individual muscle's NEMGs. Box color had no effect on the TNEMG and on the seven muscles activities(p>0.05). When precision demand was required at the end point of lifts, the mean NEMG showed higher values than no precision demand conditions: TNEMG (14% increase) and medial deltoid(40% increase), biceps brachii(10% increase), lateral triceps(26% increase), latissimus dorsi(25% increase) muscles. Those increases showed more conspicuous as the box weight increased in the muscles of medial deltoid, lateral triceps, and latissimus dorsi.

• 한국환경보건학회지
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• 제40권5호
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• pp.407-412
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• 2014

Objectives: The internal dose of ethyl parabens is important in order to evaluate the risk of this chemical. However, there are little PK model data for parabens to apply this. This experiment attempted PK modeling to ascertain PK values. Methods: Twenty mg/kg ethyl paraben was administered orally to Sprague-Dawley rats at the same point in time. The rats were sacrificed at times 0, 15, 30 and minutes, and 1, 2, 4, 8, 12, 24 hours after oral gavage. Blood and urine were collected and pretreated for analysis. Accuracy, precision and LOD (limit of detection) were calculated for this analysis. Ethyl paraben, detected by HPLC-MS, was applied to PK modeling using Berkeley Madonna. Results: This study showed 100.1-103.7% accuracy, 1.4-3.7% precision and a 1.0 ng/mL limit of detection. Orally administered ethyl paraben reached maximum concentration after 30 minutes of dosing in serum and urine of rats. The concentrations were 2,354 ng/mL in serum and 386,000 ng/mL in urine samples. These peak concentrations were excreted after one hour of intubation over 12 hours. For the pharmacokinetic parameters of ethyl paraben revealed using Berkeley Madonna, the absorption rate was 5.539/hour, the excretion rate was 0.048/hour, the half-life was 14.441 hours and AUC was 481,186 ng hour/mL. Conclusion: Orally administered ethyl paraben was absorbed rapidly in rats and excreted in urine. This chemical, ethyl paraben, accumulated in the body but was excreted over 12 hours after dosing.

• PNF and Movement
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• 제17권3호
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• pp.369-378
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• 2019

Purpose: This study investigated the effects of virtual reality-based task training (VRBTT) using a smart glove on upper extremity function and activity of daily living in stroke patients. Methods: Twenty-nine patients with chronic stroke disease were randomly allocated to two groups: the VRBTT group (n=14) and the control group (n=15). All patients received 30 minutes of standard occupational therapy, 5 times a week, for 8 weeks. The VRBTT group performed an additional 30 minutes of virtual reality-based rehabilitation training, 5 times a week, for 8 weeks. Results: Both groups showed significant improvements in upper extremity function, yielding an increase in FMA and K-WMFT (p<0.05). There was a more significant increase in the VRBTT group before and after interventions (p<0.05). There was no significant difference in MAS for the control group (p>0.05); however, there was a significant increase for the VRBTT group (p<0.05). In the activities of daily living, there was a significant difference in the values for K-MBI (p<0.05). In addition, both groups showed a significant increase for K-MBI and K-RNLI (p<0.05). Conclusion: This study showed that VRBTT using smart gloves can have a more positive effect on upper extremity function and activities of daily living in stroke patients than conventional intervention methods. A variety of virtual reality-based contents and glove-shaped wearable devices will help stroke patients in rehabilitation clinics recover and return to society.

• 한국전문물리치료학회지
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• 제13권1호
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• pp.54-60
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• 2006

This study aimed to compare movement patterns of shoulder joints between the right and left symmetry in stroke patients and control subjects. This study proposes use of the voluntary response index (VRI) calculated from quantitative analysis of surface electromyographic (sEMG) and motion data recorded during voluntary movement as a feeding task. The VRI is comprised of two numeric values, one derived from the total muscle activity recorded for the voluntary motor task (magnitude), and the other from the sEMG distribution across the recorded muscles with the similarity index (SI). Five stroke patients and five age-matched healthy controls were recruited. Feeding motion was performed using the provided spoon five times with rests taken on a chair in between tasks. EMG data were digitized and analyzed on the basis of the root mean square (RMS) envelope of activity. The average amplitude of responses was calculated. Responsiveness and clinically meaningful levels of discrimination between stroke patients and control for EMG magnitude and SI were determined. The similarity index of the results from two successive examinations of both sides apart for stroke patients and control subjects were .86 and .95 in motion analysis and .84 and .99 in electromyographic analysis. The SI of sEMG data and motion data was significantly correlated in stroke patients. The data suggest that SI is a sensitive program for comparing and analyzing the symmetry of muscle activity and motion in both sides. This analysis method has a clinical value in grading muscular activity and movement impairment after brain injury.

• 한국정보전자통신기술학회논문지
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• 제13권3호
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• pp.267-276
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• 2020

제조업 근로자는 근무 환경에서 반복 작업에 의한 근골격계 질환의 위험에 쉽게 노출되어 있다. 이는 신체를 반복적으로 이용하는 직업 특성상의 문제에 기인한다. 하지만 현재 감시 및 예방을 위한 모니터링 시스템이 제공되지 않아 매년 위험에 대한 근로자의 노출도가 증가하고 있다. 본 논문에서는 IMU 센서를 사용한 웨어러블 장치 제작을 통해 실제 작업 환경에서의 이러한 문제를 해결하는 방법에 대해 제시한다. 웨어러블 형태의 장치를 착용 후, 근골격계 움직임에 따른 회전 값을 받아와 데이터 분석을 통해 사용자의 움직임을 판단해낸다. 이때, 바이어스 제거와 누적 오차를 제거해 정교한 데이터 취득하여 이를 동적 임곗값 형식으로 분석하여 사용자의 회전 운동 횟수를 측정해내어 위험도를 판단한다. 본 논문에서 제안한 웨어러블 장치를 이용 팔꿈치 근골격계 질환에 대한 회전 횟수를 측정하는 웹 페이지를 통해 본 방법의 효과를 확인할 수 있었다.